You may bring in to the test a 3"x5" index card, prepared in your own handwriting, containing any information you like.

Part 1. The Science of Genetics
 

You need to know about the Human Genome Project and the National Center for Human Genome Research. In particular, you need to know, about each institution,

• when it was formed,
• why it was created,
• how it is funded,
• what its strategy is, and
• the main ethical and legal issues it investigates.

• Genes: the units of heredity
• DNA: the hereditary material, composed of sugar, phosphate, and nitrogenous bases and shaped in a double helix
• Chromosomes: the packages of genes
• Cell division: how the body grows
• DNS, RNA, Protein: the central dogma

• Autosomal dominant
• fifty percent chance for recurrence
• variable expression among family members
• reduced penetrance
• Autosomal recessive
• more common among certain ethnic groups and in the presence of genetic relatedness
• 25% chance for an affected child; 50% chance for carrier children; 25% for child without gene

• extra or missing chromosomes (e.g. Down syndrome)
• effects on mental or physical development

• a genetic disease at the cellular level
• not always inherited
• a multistep process
• characterized by immortalization, transformation of cells, and metastasis

• Alcoholism runs in families, but it is not all genetic
• Adoption study showing genetic influence
• Cloninger's division of alcoholics into Type I and Type II
• Genes influence the body's tolerance of alcohol