| Villian(s) Name | Name of Episode | Series |
|---|---|---|
| 10,000 Volt Ghost | Watt a shocking ghost | 1976 |
| 49 Miner | Mine your own business | 1969 |
| Apeman | Never Ape an Apeman | 1969 |
| Beast of Bottomless Lake | The Beast of Bottomless Lake is Awake | 1976 |
| Black Night | What a Night for a Knight | 1969 |
| Captain Clemens | The Creepy Heep from the Deep | 1976 |
| Caveman | Scooby's Night With a Frozen Fright | 1969 |
| Charlie the Robot | Foul Play in Funland | 1969 |
| Creeper | Jeepers! It's the Creeper | 1969 |
| Creepy Heap from the Deep | The Creepy Heep from the Deep | 1976 |
| Demon | A Frightened Hound Meets Demons Underground | 1976 |
| Demon Shark | There's a Demon Shark in the Foggy Dark | 1976 |
| Diabolical Disc Demon | The Diabolical Disc Demon | 1976 |
| Dr. Coffin | Harum Scarum Sanitarium | 1976 |
| Dr. Jekyll | Nowhere to Hyde | 1969 |
| Dracula | A Gaggle of Galloping Ghosts | 1969 |
| Frankenstein | A Gaggle of Galloping Ghosts | 1969 |
| Gator Ghoul | The Gator Ghoul | 1976 |
| Ghost Clown | Bedlam in the Bigtop | 1969 |
| Ghost Native Shaman | A Bum Steer for Scooby | 1976 |
| Ghost of Captain Piscato | The mystery of Diablo Doro | 1976 |
| Ghost of Finnyan MacDuff | A Highland Fling with a Monstrous Thing | 1976 |
| Ghost of Juan Diego | Don't Go Near the Fortress of Fear | 1976 |
| Ghost of King Katazuma | The Fiesta Host is an Aztec Ghost | 1976 |
| Ghost of Ramblin Ghost | The Mystery of the Rambling Ghost | 1976 |
| Ghosts of Benedict Arnold Major Andre and William Demont | Spirits of 76 | 1976 |
| Ghosts of Elias Kingston | What the Hex is going on? | 1969 |
| Ghosts of Geronimo | Decoy for a Dognapper | 1969 |
| Ghostly Gondoleer | A Menace in Venice | 1976 |
| Giant Mantis | The Creepy Creature At Vulture's Claw | 1976 |
| Headless Horseman | The Headless Horsemen of Halloween | 1976 |
| Headless Spectre | Haunted House Hangup | 1969 |
| Kelp Monster | The mystery of Diablo Doro | 1976 |
| Loch Ness Monster | A Highland Fling with a Monstrous Thing | 1976 |
| Mano Tiki Tia | A Tiki Scare is No Fair | 1969 |
| Mano Tiki Tia-Full Size | A Tiki Scare is No Fair | 1969 |
| Merlin | Scared A lot in Camelot | 1976 |
| Momba Womba | Momba Wamba and the Voodoo Hoodoo | 1976 |
| Momba Zombie | Momba Wamba and the Voodoo Hoodoo | 1976 |
| Moon Monster | Scooby's Chinese Fortune Cookie Caper | 1976 |
| Mr. Hyde | Nowhere to Hyde | 1969 |
| Mummy | Scooby Doo and a Mummy Too | 1969 |
| No-Face Zombie | The No-Faced Zombie Chase case | 1976 |
| Octopus Monster | The Mystery of Diablo Doro | 1976 |
| Old Iron Face | The Creepy Case of Old Ironface | 1976 |
| Owl Men | Watch Out! The Willawaw! | 1976 |
| Phantom of Milo Booth | Chiller Diller Movie Thriller | 1976 |
| Phantom of Vasquez Castle | Hassle in the Castle | 1969 |
| Phantom Puppeteer | The Backstage Rage | 1969 |
| Phantom Racer | Spooky Case of the Grand Prix Race | 1976 |
| Phantom Shadows | A Night of Fright is No Delight | 1969 |
| Pterodactyl | Hang in There, Scooby Doo | 1976 |
| Redbeard's Ghost | Go Away Ghost Ship | 1969 |
| Scare Pair | Mystery Mask Mix-Up | 1969 |
| Skeleton Men | A Creepy Tangle in the Bermuda Triangle | 1976 |
| Snow Beast | A Scary Night with a Snowbeast Fright | 1976 |
| Snow Ghost | That's Snow Ghost! | 1969 |
| Space Kook | Spooky Space Kook | 1969 |
| Spectre of Ebeneezer Crabb | High Rise Hair Raiser | 1976 |
| Stone Creature | The Fiesta Host is an Aztec Ghost | 1976 |
| Tanooka | A Bum Steer for Scooby | 1976 |
| Tar Monster | The Tar Monster | 1976 |
| Technicolor Phantoms (Chocolate, Vanilla & Strawberry) | The Ghost of the Bad Humor Man | 1976 |
| UFO | A Creepy Tangle in the Bermuda Triangle | 1976 |
| Vampire of skull island | Vampires and Bats and Scaredy Cats | 1976 |
| Viking | The Curse of Viking Lake | 1976 |
| Warlock Anthos & Hound | The Warlock of Wimbeldon | 1976 |
| Wax Phantom | Don't Fool With a Phantom | 1969 |
| Werewolf | Who's Afraid of the Big Bad Werewolf | 1969 |
| Willawaw | Watch Out! The Willawaw! | 1976 |
| Witch | Which Witch is Which | 1969 |
| Witch Doctor | A Tiki Scare is No Fair | 1969 |
| Witch of Salem | Two Switch a Witch | 1976 |
| Wolfman | A Gaggle of Galloping Ghosts | 1969 |
| Zen Tuo | Mystery Mask Mix-Up | 1969 |
| Zombie | Which Witch is Which | 1969 |
