Drug Class |
Examples |
Mechanisms of Action |
Drugs Used To Alter Moods and States of Consciousness |
STIMULANTS (produce psychomotor arousal; treat attention deficit disorder
|
Sympathomimetics |
Dextroamphetamine
Methylphenidate |
Monoamine (DA & NE) agonist; increase
release; block re-uptake |
Cholinomimetics |
Nicotine
Muscarine |
Ach (acetylcholine) agonist
(high dose blocks) |
Xanthines |
Caffeine (recommended
200mg/day; one cup = 90-150mg)
Theophylline
|
Block adenosine receptors;
GABA antagonist |
Convulsants |
Strychnine |
Glycine antagonist |
DEPRESSANTS (produce sedation; treat pain, anxiety, sleep disorders)
|
Opioids |
Morphine
Ether |
Endogenous opiate agonist |
Barbiturates |
Secobarbital |
GABA agonist |
Barbiturate-like |
Meprobamate |
Similar to barbiturates |
Organic solvents |
Alcohol
Ether |
Disrupt neuronal membrane;
may facilitate GABA |
HALLUCINOGENIC (produce distorted perception)
|
NE-like (norepinephrine) |
Mescaline |
Alter 5HT activity |
5HT-like (serotonin) |
LSD |
Alter 5HT activity |
Other |
Marijuana
Anti-cholinergics, PCP |
Alter 5HT activity |
Drugs Used to Treat Psychological Disorders |
ANTIPSYCHOTICS (treat schizophrenis; also delirium and dementia)
|
Phenothiazines |
Chlorpromazine |
Block DA receptors |
Butyrophenones |
Haloperidol |
Block DA receptors |
Other |
Clozapine |
Block DA receptors |
ANTIDEPRESSANTS (treat depression and bipolar disorder)
|
Tricyclics (secondary
amines)
Tricyclics (tertiary amines) |
Nortriptyline
Imipramine
Clomipramine |
Block NE re-uptake
Block 5HT re-uptake
Block 5HT re-uptake |
Heterocyclics |
Fluoxetine |
Block NE & %HT re-uptake |