Victorious in the War, the UFP found itself weakened militarily and straining to secure its territory. Starfleet losses were heavy, with nearly a third of its ships destroyed and casualties in the hundreds of thousands. There is an ongoing effort to rebuild. Older starships have been kept in service and new, more advanced designs are being produced. The Federation has also taken on the task of helping Cardassia recover, making the former Union little more than a Federation dependency. The real threat to piece, many believe, has shifted back to the Romulan Star Empire, of all the powers of the Alpha Quadrant the least affected by the war .
Bajor first vied for Federation membership in 2373. However, this was delayed by the impending Dominion invasion of the Alpha Quadrant. Bajor signed a nonaggression pact with the Dominion prior to the War, though some Bajorans were involved in fighting on the Federation side. Following the defeat of the Dominion, Bajor once again applied for Federation membership, which wqas granted last year (2379). The Bajoran military has been incorporated into Starfleet.
The Cardassian Union no longer exists. Cardassia Prime was devastated at the end of the Dominion War and most of the systems in the old Union, attacked by Alliance as well as Dominion forces, have broken away. In 2377, Cardassia was granted protectorate status under Federation control. It has been estimated that it will take decades before the Cardassian people are self-sufficient.
In 2373, the Cardassian Union launched a grand offensive against all of Cardassia's enemies. With their Jem'Hadar allies, the Cardassians swept the Demilitarized Zone, rapidly wiping out every Maquis colony. In the aftermath of the offensive, only small pockets of Maquis remained, isolated and completely impotent. Most of the survivors have been captured by the Federation and imprisoned. But a few remain on the run.
THE KLINGON EMPIRE
THE ROMULAN STAR EMPIRE
The emergence of the Dominion threat in 2370 led to the first thaw in relations with the Federation. Though bound by necessity, an alliance with the Federation and the Klingon Empire was less than amicable. All sides knew a struggle for dominance in the Alpha Quadrant would follow once the war ended. In the Battle of Cardassia, the Romulans suffered heavy losses and, after the Dominion's surrender, the Empire withdrew into isolation again. Open conflict with the Federation or Klingons has been delayed by the Reman military coup of 2379, leaving Romulus preoccupied with its own internal issues. However, the threat of future Romulan aggression looms large.
THE FERENGI ALLIANCE
The Ferengi maintained official neutrality during the Dominion War, though they believed their natural business interests to lie with the Alpha Quadrant powers. Since then, the Alliance has maintained its unaligned position, giving it significant economic influence in the Alpha Quadrant. Evidently, the Ferengi are taking advantage of the chaotic state of affairs in the old Cardassian Union to expand profits.
Nothing has been seen of the Borg since the return of USS Voyager in 2378 (two years ago). It is assumed that the destruction of their transwarp hub, resulting in the death of the Borg Queen and the devastation of the Unicomplex, has set back any plans they may have had to invade the Alpha/Beta quadrants. However, Starfleet remains vigilant and is continuing to integrate anti-Borg technology into new starship designs.