Scientists in the laboratory of Professor Harvey Jian-Min Hou at UMass Dartmouth are interested in elucidating the structure and function of membrane proteins including photosynthetic reaction centers and G protein-coupled receptors and developing technologies in solar fuel production and drug discovery. Four ongoing research projects are (1) Structural and Mechanistic Studies of Mn-oxo Complex and Co-based Water-splitting catalysts, (2) Molecular Mechanisms of American Cranberries Against Environmental Stress, (3) Photoacoustic Studies of Photobiological Reactions, and (4) Structure and Function of G Protein-coupled Receptors.
Research Interests
Biochemistry and Analytical Chemistry, Photosynthesis, Solar Energy Catalysis and Nanotechnology, G Protein-coupled Receptors, Cranberry Plant Biology
Representative Publications
1. Harvey J.M. Hou* (2010) Structural and Mechanistic Aspects of Mn-oxo and Co-based Compounds in Water Oxidation Catalysis and Potential Application in Solar Fuel Production, J. Integr. Plant Biol., 52, 704-711
2. Harvey J.M. Hou* and Thomas P. Sakmar* (2010) Methodology of Pulsed Photoacoustics and Its Application to Probe Photosystems and Receptors, Sensors, 10, 5642-5667
3. Harvey J.M. Hou*, Gaozhong Shen, Vladimir A. Boichenko, John H. Golbeck and David Mauzerall* (2009) Thermodynamics of charge separation of photosystem I in the menA and menB null mutants of Synechocystis sp. PCC 6803 determined by pulsed photoacoustics, Biochemistry, 48, 1829-1837
4. Harvey J.M. Hou and David Mauzerall (2006) The A- to FA/B Step in Synechocystis 6803 Photosystem I is Entropy Driven, J. Am. Chem. Soc., 128, 1580-1586
5. Elsa C. Y. Yan, Manija A. Kazmi, Ziad Ganim, Jian-Min Hou, Douhai Pan, Belinda S. W. Chang, Thomas P. Sakmar and Richard A. Mathies (2003) Counterion Switch in the Photoactivation of the G Protein-Coupled Receptor Rhodopsin, Proc. Natl. Acad. Sci. USA, 100, 9262-9267
Harvey Hou, Ph.D.
Assistant Professor
Department Chemistry and Biochemistry
UMass Dartmouth
285 Old Westport Road
N. Dartmouth, MA 02747
Tel: (508) 999-8234
Fax: (508) 999-9167
Email: hhou@umassd.edu
Lab Phone Numbers:
(508) 999-8297 (lab, II-311B)
(508) 999-8239 (lab, II-304B)
(508) 910-6676 (lab, II-326F)
(508) 999-9247 (lab, Dion-006)
