DUCK AND COVER! It's Anti-Venom and Punisher vs. one of the largest, most powerful and most ruthless drug cartels on the planet. Our money's on the guys with the biggest guns...and the skulls on their chests. Zeb Wells & Paulo Siqueira deliver the senses-shattering conclusion to NEW WAYS TO LIVE!

A locked room mystery! A string of brutal murders! A missing girl! One of Peter Parker's closest friends on the brink of ruin! This looks like a job for the Amazing Spider-Sleuth... and all clues point to the sinister SANDMAN! But all of Spidey's classic villains are being reinvented as part of "THE GAUNTLET", and Sandy is no different -- so nothing is what it seems!

The Sandman has vacillated between good and evil over the years, joining the Sinister Six and the Frightful Four...as well as becoming a reserve Avenger and a member of Silver Sable's Wild Pack. But as of this issue, and forever more, he will always be known as a villain -- one of the worst in the Wall-Crawler's Rogues Gallery -- and it's all Spider-Man's fault! Find out the shocking reason why in this issue as "THE GAUNTLET" continues!

Peter Parker’s got a case of the clones…and the only man with the cure is Doctor Octopus! But if the nefarious Kaine has his way, this is one check up neither will survive!

The Gauntlet continues to close around Spider-Man in this heartbreaking story of love, loss and lust for power as the Rhino charges into Spider-Man's life, out to make a name for himself...by killing the Rhino?

MYSTERIO is back from the dead...and he's not alone! When deceased members of the Maggia crime family return from beyond the grave, the balance of power shifts in their gang war with Hammerhead and the Inner-Demons. Can Spider-Man and crime scene investigator, Carlie Cooper, solve this mystery...before it gets a little too personal?

How long can Mysterio play with Spidey's head before the web-slinger finally snaps?! The mind games keep ratcheting up as the body count goes up, down, and...into the negatives? Some bad guys just won't die and others can't stay dead! So which long-thought deceased Spider-Man character is back now?! It may only be January, but get ready for the most unbelievable Spider-Man moment of the year!

From the pages of Amazing Spider-Man! The last Jackpot died in combat alongside Spider-Man – so who is the New Jackpot putting fear into the hearts of street criminals? Why has BOOMERANG targeted her for death? And how is THE ROSE involved? Find out this January as founding Web-head Marc Guggenheim returns to the Spider-Verse alongside rising star ADRIANA MELO (MS. MARVEL) to bring the next great marvel heroine, Jackpot!

MAXIMUM CLONAGE! It’s Hoo-Ha Time as MJ goes into labor while Peter, Ben Reilly, and Kaine have a clone war for the ages...in the heart of mid-town Manhattan! Only one will walk away as the controversial crossover rockets to its mind-blowing conclusion!

Behold Mysterio...looks can be more than just deceiving – they can drive you mad. As the Master of Illusion makes his triumphant return to the pages of Amazing Spider-Man, webbed wonders FRED VAN LENTE and BARRY KITSON bring you the real story of Quentin Beck...or is it just another illusion? Then, over in THE SPECTACULAR SPIDER-GIRL, Fury the Goblin Queen has a familiar ally as the cult of the Goblin makes its last stand against May-Day Parker – and a gang war looms in New York City! Finally, as the events of The Gauntlet unfold, Mr. Negative and his forces have laid conspicuously low...and the Hammer drops hard on New York City...as HAMMERHEAD makes his move in New York’s underworld...and he may not be playing for the side you’d think...

MYSTERIO'S made his big move and a criminal empire is his for the taking! Or is that just more sleight of hand? More mobsters! More mayhem! More magic tricks! And a fight to the finish with MR. NEGATIVE versus SPIDER-MAN versus MYSTERIO! The big question is: What prize goes to the winner?

SPIDEY needs a favor from the BLACK CAT. Nothing big. He just needs her help stealing one of MR. NEGATIVE'S most valuable possessions. It's not like anything could go oh-so-horribly wrong! Also in this ish: a dark turn for CARLIE COOPER, a disturbing development for CURT CONNORS, and a malicious move by...AUNT MAY?!

As the Gauntlet rages on around him, the spotlight is on Peter Parker's original archenemy-turned-best friend, Flash Thompson. Since losing his legs in service to his country, Flash Thompson's not been deterred by his physical limitations. But even a hero can have his limits. Greg Weisman, one of the brains behind the smash TV hit Spectacular Spider-Man, teams with Luke Ross (CAPTAIN AMERICA) to bring a touching story of Flash Thompson coming to terms with his new life. Then, Fred Van Lente and Joe Quinones (WEDNESDAY COMICS) bring Spider-Man face-to-face with Morbius, The Living Vampire!

With one choice, Sarah Ehret gave up a normal life and embraced her destiny as the vigilante Jackpot. But the underworld isn’t about to go down without a fight. As Jackpot finds herself locked in combat with a resurgent WHITE RABBIT and in the crosshairs of THE ROSE, not even the wisdom and friendship of THE AMAZING SPIDER-MAN and MR. FANTASTIC will be enough to help Jackpot as BOOMERANG closes in for the kill. Be warned – someone doesn’t walk away from this fight alive. Marc Guggenheim (AMAZING SPIDER-MAN) and Adriana Melo (MS. MARVEL) bring you the defining moments of the next great Marvel hero!

See how the controversial classic SHOULD have ended, straight from the pens of the Clone Saga’s original architects, Tom DeFalco and Howard Mackie. Heroes are born, heroes die, and demons from the past return with a vengeance. Once the smoke clears only one Spider-Man will be left standing! Don’t miss the finish that answers ALL your lingering questions, Spidey fans!

Curt Connors has played a tricky role in the life of Peter Parker – at his best, he’s an ally whom even Spider-Man must keep an eye on. At his worst, he’s The Lizard – a ferocious creature with killer instincts – and Connors’ fine scientific mind to boot. Web-head Stalwarts Fred Van Lente and Barry Kitson bring you the tragic case of Curt Connors – while Zeb Wells and Xurxo Penalta gives a preview of his synapse-shattering return later this year in the pages of AMAZING SPIDER-MAN! Meanwhile, in the Spectacular Spider-Girl, a brand new era is born for Mayday Parker as she finally gets through to her clone, April – and just in time, as a Mob War EXPLODES – and Midtown High is caught in the crossfire!