ALVIN A. HOLDER, Ph.D., MRSC, CChem
E-mail: aaholder@lamar.colostate.edu
OBJECTIVE
To obtain a tenured-track faculty position at an academic institution in order to carry out teaching and research at the undergraduate and graduate levels.
EDUCATION
05/94: Ph.D. (Inorganic Chemistry), University of the West Indies (U.W.I.), Mona Campus, Jamaica. Advisor: Professor Tara P. Dasgupta. Thesis title: "Synthesis, Characterisation, and Reactivity of some Coordinated Oxo-Molybdenum(VI) Complexes in Aqueous Solution."
07/89: B.Sc. (Special Chemistry), upper second class honors, U.W.I., Mona Campus, Jamaica.
RESEARCH INTERESTS
My area of research centers around biological and inorganic chemistry, bioinorganic and inorganic reaction mechanisms, which includes the following:
(a) Synthesis and characterization of supramolecular polypyridyl ruthenium(II)/rhodium(III) complexes for bioinorganic studies of DNA recognition and reactions by metallointercalators, followed by their uses as anti-cancer agents in photodynamic therapy.
(b) The synthesis, characterization, and biomedical uses of vanadium complexes in alleviating diabetes.
(c) The synthesis, characterization, reactivity, and biomedical uses of NOx-containing compounds.
(d) Synthesis and characterization of novel non-hydrolyzable nucleotides; also cobalt(III), chromium(III) and vanadium(IV/V) complexes. Their uses as inhibitors of the enzymatic synthesis of DNA through the use of DNA polymerase .
(e) The use of EPR {V(IV), Cu(II), and Mo(V) at ambient and liquid nitrogen temperatures}, NMR (95Mo, 13C, 1H, 51V, and 31P), and other physical means in the structural elucidation of various transition metal complexes.
RESEARCH EXPERIENCE
05/04-present: Postdoctoral Fellow, Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, U.S.A., with Professor Debbie C. Crans.
(a) Synthesis and characterization of novel non-hydrolyzable nucleotides and chromium(III) complexes, which are being tested as inhibitors of the enzymatic synthesis of DNA through the use of DNA polymerase beta.
(b) Synthesis and characterization of vanadium complexes, which are being tested as alleviators of diabetes.
(c) Characterization of transition metal complexes in aqueous solution utilizing EPR {V(IV) at ambient and liquid nitrogen temperatures}, UV/Visible, 31P, 1H, 13C, and 51V NMR spectroscopy.
(d) Supervision of undergraduate students in the research area of vanadium chemistry.
(e) Participated as a judge in an undergraduate research poster competition.
09/03-04/04: Postdoctoral Fellow, Department of Biochemistry, The Ohio State University, Columbus, Ohio 43210, U.S.A., with Professor Peng George Wang.
(a) Studied the binding of some known intercalators of DNA with the use of isothermal titration calorimetry and the quartz crystal microbalance.
(b) Studied enzymatic processes involving the enzyme, alpha-1,3-galactosyltransferase.
08/02-06/03: Research Scientist, Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, U.S.A., with Professor Karen J. Brewer.
(a) Synthesized and characterized supramolecular polypyridyl ruthenium(II)/rhodium(III) complexes, which were used in the photocleavage of pUC18 and pBluescript DNA plasmids.
(b) Utilized photochemical, fluorescence microscopy, and electrochemical techniques in the research area of DNA recognition and reactions by metallointercalators.
(c) Utilized agarose gel electrophoresis, polyacrylamide gel electrophoresis, and chromato-graphy in the separation of photocleaved DNA.
(d) Carried out experiments involving the growing of Vero cells, and the inhibition of cell growth of Vero cells in vitro with ruthenium(II) and osmium(II) complexes in aqueous solution.
(e) Supervised undergraduate students in the research area of ruthenium chemistry, the photocleavage of pUC18 and pBluescript DNA plasmids, and the inhibition of cell growth of Vero cells in vitro with ruthenium(II) and osmium(II) complexes.
08/96-08/97: Postdoctoral Fellow/Visiting Professor, Exxon Research and Engineering Company, New Jersey 08801, U.S.A., with Dr. Edward I. Stiefel.
(a) Synthesized, characterized, and studied the reactivity of nitrosyl complexes, molybdenum, rhenium, and tungsten supramolecular clusters.
(b) Application of such clusters as potential anti-friction agents.
06/95-09/95: Leverhulme Fellow, Department of Chemistry, University of Newcastle, Newcastle upon Tyne, NE1 7RU, U.K., with Professor A. Geoffrey Sykes.
(a) Synthesized, characterized, and studied the reactivity of molybdenum and tungsten supramolecular clusters (incomplete and complete cuboidal clusters) in aqueous solution.
10/90-05/94: Graduate student, U.W.I., Mona Campus, Jamaica, with Professor Tara P. Dasgupta.
(a) Synthesized some novel cobalt/chromium(III) ammine complexes, containing the molybdate(VI) oxoanion as monodentate and bidentate ligands; then characterized the complexes by UV/Visible spectroscopy, infrared spectroscopy, 95Mo NMR spectroscopy, and X-Ray Powder Diffraction.
(b) Carried out electrochemical studies on the cobalt/chromium(III) ammine complexes.
(c) Carried out kinetic studies on the formation and acid/base hydrolysis of the cobalt/chromium(III) ammine complexes using stopped-flow and conventional spectrophotometry.
(d) Carried out kinetic studies of the electron-transfer reactions between [(H3N)5CoIIIOMoVIO3]+ and (1) aqueous sulfite, (2) K4Fe(CN)6, (3) L-ascorbic acid, and (4) L-cysteine using stopped-flow and conventional spectrophotometry.
(e) Carried out EPR studies for the reaction involving [(H3N)5CoIIIOMoVIO3]+ and L-cysteine in order to detect the very reactive Mo(V) monomer.
TEACHING EXPERIENCE
05/02-06/02: Visiting Professor in Chemistry, Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, U.S.A.
(a) Lectured the course General Chemistry 1035 in the first Summer session.
08/01-05/02: Visiting Assistant Professor in Chemistry/Research Assistant Professor, The University of Toledo, College of Arts and Sciences, Department of Chemistry, Toledo, Ohio 43606, U.S.A.
(a) Lectured general chemistry courses.
(b) Supervised the general chemistry laboratory course CHEM-1150: Concepts In Chemistry Laboratory.
(c) Supervised the general chemistry laboratory course CHEM 1260: Chemistry for Life Sciences Laboratory I and II.
(d) Supervised the advanced inorganic chemistry course: CHEM 3870: Advanced Laboratory II.
(e) Lectured the graduate course: CHEM 4980/6330/8330: Special Topics in Chemistry (Spectroscopic Methods and Analysis of Spectra).
(f) Conducted recitation classes in Chemistry 1090, Chemistry 1230, and Chemistry 1240.
01/94-08/01: Temporary Assistant Lecturer in Physical Chemistry, Lecturer in Physical and Inorganic Chemistry, U.W.I., Cave Hill Campus, Barbados.
(a) Lectured several courses in analytical, inorganic, and physical chemistry.
(b) Single-handedly developed, coordinated, and lectured a bioinorganic chemistry course.
(c) Instrumental in co-developing and co-lecturing a transition metal chemistry II course.
(d) Conducted recitation classes for courses involving analytical, inorganic, and physical chemistry.
(e) Supervised laboratory courses involving analytical, inorganic, and physical chemistry.
(f) Directly supervised a Ph.D. student, two M.Phil. students, and 14 undergraduate students.
(g) Instrumental in coordinating the first chemistry seminar series.
10/93-01/94: Tutor in Chemistry, U.W.I., Mona Campus, Jamaica.
(a) Conducted recitation classes in inorganic, organic, and physical chemistry courses at the introductory and advanced levels.
(b) Supervised and graded inorganic, organic, and physical laboratories at the introductory and advanced levels.
10/90-01/94: Teaching Assistant (Demonstrator), U.W.I., Mona Campus, Jamaica.
(a) Supervised and graded inorganic, organic, and physical laboratory courses at the introductory and advanced levels.
09/89-07/91: High School Chemistry Teacher.
(a) Taught the equivalent of general chemistry at various secondary schools in Barbados and Jamaica.
STUDENTS SUPERVISED
Graduate Dissertations
10/03: Sophia C. Marshall, Ph.D. (Inorganic Chemistry), U.W.I., Cave Hill Campus, Barbados. Thesis title: "The Kinetics and Mechanism of the Decomposition of Several Vasodilators by a Bronchoconstrictor, Aqueous Sulphite."
Present Graduate Students
08/02-present: Ross F.G. Brown (M.Phil.). Thesis title: "Studies of The Interaction Between Nitric Oxide and S-Nitrosothiols with Analogues of Hydroxocobalamin In Aqueous Solution-Clues from Physiological and Physical Studies." Co-supervised by Professor Tara P. Dasgupta, U.W.I., Mona Campus, Jamaica.
08/01-present: Vince C.R. Payne (Ph.D.). Thesis title: "Synthesis, Characterisation of some Transition Metal Complexes of Dipicolinic Acid in Non-Aqueous Media." Co-supervised by Dr. Anthony M. Newton, U.W.I., Cave Hill Campus, Barbados.
08/99-present: Gabriel Harewood (Ph.D.). Thesis title: "Syntheses, Characterization, and Reactivity of Some Salicylaldimine-Based Ligands (Schiff Bases) and Corresponding Metal Complexes." Co-supervised by Professor Tara P. Dasgupta, U.W.I., Mona Campus, Jamaica.
Present Undergraduate students
05/04-present: Barbara K. Hughes and Shelly Hay, Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, U.S.A
Former Undergraduate Students, U.W.I., Cave Hill Campus, Barbados (Out of a total of 14)
00-01: Robin-Simone Rocke (U.WI., St. Augustine Campus, Trinidad and Tobago), Celina Franklin, and Ezra Maynard.
99-00: Martin Hall and Gabriel Harewood (U.W.I., Mona Campus, Jamaica).
98-99: Ross F.G. Brown (U.W.I., Mona Campus, Jamaica), Maria D. Cozier, Walter Alleyne Jnr. (U.W.I., Mona Campus, Jamaica), and Christopher O. Bovell (University of Bristol, U.K.).
97-98: Alex Waterman (University of Surrey).
95-96: Junior Welch.
94-95: Shawn Phillips (University of Newcastle, U.K.), Leslie Wellington, and Kendi Cumberbatch-King
SKILLS
(a) Excellent communicative and collaborative skills (grant proposals and publications).
(b) Extensive experience in the use of conventional and stopped-flow UV/Visible spectrophotometers, Schlenck lines, glove box, and infrared spectrometers.
(c) Extensive experience in techniques involving isothermal titration calorimetry (ITC), quartz crystal microbalance (QCM), mass spectrometry, Raman spectrometry, cyclic voltammetry, crystal growth for X-ray crystallography, syntheses and chromatographic separations under oxygen free conditions.
(d) Extensive experience in the use of biological protocols, for example, fast liquid chromatography (FPLC), electrophoresis, dialysis, equilibrium dialysis, and ultrafiltration, to name a few.
(e) Extensive experience in the isolation and purification of DNA plasmids from E. coli.
(f) Very proficient in molecular biology, fluorescence microscopy, handling of cells in vitro, photochemistry, enzymology, and many other protocols, which are all biochemically related.
(g) Synthetic inorganic chemist, utilizing various organic ligands for catalytic processes, bioinorganic/medicinal chemistry, and photodynamic therapy.
(h) Extensive experience in EPR {V(IV), Cu(II), and Mo(V) at ambient and liquid nitrogen temperatures} and NMR measurements (95Mo, 13C, 1H, 51V, and 31P) for structural elucidation of organometallic compounds.
(i) Experience in the synthesis and characterization of nucleotides, and their coordination complexes with transition metal ions.
(j) Trained at Exxon Research and Engineering Company, New Jersey 08801, in the safe use of a nitric oxide producing apparatus for the synthesis of nitrosyl complexes.
AWARDS
08/05: American Chemical Society Biological Chemistry Division Travel Award to attend the 230th American Chemical Society National Meeting, Washington, D.C., August 28-September 01, 2005.
03/03: Postdoctoral Travel Grant from Virginia Polytechnic Institute and State University to attend the 225th American Chemical Society National Meeting, New Orleans, Louisiana, March 23-27, 2003.
07/01-08/01: Recipient of an award from the Caribbean Academy of Sciences (CARISCIENCE) for research conducted at the University of the West Indies, Mona Campus, with Professor Tara P. Dasgupta.
07/00-08/00: Recipient of the American Chemical Society International Initiatives Program for collaborative visits to New York University and Wayne State University, Detroit, Michigan.
08/96-08/97: U.W.I./Inter-American Development Bank Staff Training Program Award: Postdoctoral Fellow/Visiting Professor at Exxon Research and Engineering Company, Clinton Township, New Jersey, U.S.A., with Dr. Edward I. Stiefel. US$39,000
06/95-09/95: Leverhulme Fellowship for research with Professor A. Geoffrey Sykes at the University of Newcastle, Newcastle upon Tyne, U.K.
AFFILIATIONS
1997-present: The Royal Society of Chemistry, U.K.
1997-present: The American Chemical Society.
PROFESSIONAL SERVICE
09/02: Wrote questions for a general chemistry text ("General Chemistry", 7th edition by Kenneth W. Whitten, Raymond E. Davis, Larry M. Peck, and George G. Stanley), Brooks/Cole Publishing, U.S.A.
12/99-08/01: Secretary of the University Staff Gym Committee, U.W.I., Cave Hill Campus, Barbados.
09/98-05/99: Chairman, Department of Biological and Chemical Sciences' Safety Committee, U.W.I., Cave Hill Campus, Barbados.
09/95-08/01: Chemistry Seminar Co-ordinator, Department of Biological and Chemical Sciences, U.W.I., Cave Hill Campus, Barbados.
09/95-05/96: Dean's Nominee for the Library Advisory Committee, U.W.I., Cave Hill Campus, Barbados.
03/95-present: Assistant Chief Examiner in Chemistry (the Caribbean Secondary Education Certificate) for the Caribbean Examinations Council, Barbados.
09/94: Co-developed the first undergraduate chemistry research projects in the Department of Chemistry, U.W.I., Cave Hill Campus, Barbados.
RESEARCH GRANTS
12/99-12/00: A Royal Society of Chemistry John William Thomas Jones Research Fund Grant for studies on the chemistry of rhenium complexes. US$1,800
12/98-12/99: A Royal Society of Chemistry John William Thomas Jones Research Fund Grant for studies on the chemistry of rhenium complexes. US$1,800
10/98-10/00: A Wellcome Trust International Research Development Award. Research involving the bioinorganic chemistry of purple acid phosphatase isolated from soybeans, sweet potatoes, and the porcine uterine fluids. A collaborative effort with Professor A. Geoffrey Sykes of the Department of Chemistry, University of Newcastle, Newcastle upon Tyne, NE1 7RU, U.K. US$62,000
06/98-09/98: A Wellcome Research Travel Grant. Research involving the bioinorganic chemistry of purple acid phosphatase isolated from soybeans, sweet potatoes, and the porcine uterine fluids. A collaborative effort with Professor A. Geoffrey Sykes at the Department of Chemistry, University of Newcastle, Newcastle upon Tyne, NE1 7RU, U.K. US$2,800
PUBLICATIONS
1. Holder, Alvin A.; Dasgupta, Tara P. "Synthesis, acid hydrolysis and formation of the [(H3N)5CoOMoO3]+ ion in aqueous solution." J. Chem. Soc., Dalton Trans. 1996, 2637-2643.
2. Varey, Jane E.; Lamprecht, Gert J.; Fedin, Vladimir P.; Holder, Alvin A.; Clegg, William; Elsegood, Mark R.J.; Sykes, A. Geoffrey. "Interconversion and Reactivity of Two Heterometallic Tin-Containing Cuboidal Clusters from [Mo3S4(H2O)9]4+: X-ray Structure of the Single Cube with an Mo3SnS4 Core." Inorg. Chem. 1996, 35, 5525-5530.
3. Holder, Alvin A.; Dasgupta, Tara P. "Mechanism of the Oxidation of L-Ascorbic Acid by the Molybdatopentaamminecobalt(III) Ion in Aqueous Solution." Transition Met. Chem. 1997, 22, 135-140.
4. Holder, Alvin A.; Dasgupta, Tara P.; McFarlane, William; Rees, Nicholas H.; Enemark, John H.; Pacheco, Andy; Christensen; Kenner. "Syntheses, Characterisation, Infrared and 95Mo NMR of Some Coordinated Oxo-Molybdenum(VI) Complexes." Inorg. Chim. Acta 1997, 260, 225-228.
5. Holder, Alvin A.; Dasgupta, Tara P. "Synthesis, Acid Hydrolysis and Formation of the Molybdatopentaamminechromium(III) Ion in Aqueous Solution." Inorg. Reaction Mech. 1999, 1, 177-188.
6. Holder, Alvin A.; Brown, Ross F.G.; Marshall, Sophia C.; Payne, Vince C.R.; Cozier, Maria D.; Alleyne, Walter A.; Bovell, Christopher O. "Mechanism of the oxidation of L-ascorbic acid by the bis(pyridine-2,6-dicarboxylate)cobaltate(III) ion in aqueous solution." Transition Met. Chem. 2000, 25, 605-611.
7. Holder, Alvin A.; Dasgupta, Tara P. "Kinetics and Mechanism of the Reduction of the Molybdatopentaamminecobalt(III) Ion by Aqueous Sulfite and Aqueous Potassium Hexacyanoferrate(II)." Inorg. Chim. Acta 2002, 331, 279-289.
8. Fang, Zhenglai; Swavey, Shawn; Holder, Alvin; Winkel, Brenda; Brewer, Karen J. "DNA Binding of Mixed-Metal Supramolecular Ru,Pt Complexes." Inorg. Chem. Commun. 2002, 5, 1078-1081.
9. Holder, Alvin A.; Marshall, Sophia C.; Wang, Peng George; Kwak; Chee-Hun "The Mechanism of the Decomposition of a Bronchodilator, S-Nitroso-N-acetyl-D,L-penicillamine (SNAP) by a Bronchoconstrictor, Aqueous Sulfite:- Detection of the N-nitrosohydroxylamine-N-sulfonate ion." Bull. Korean Chem. Soc. 2003, 24, 350-356.
10. Holder, Alvin A.; Swavey, Shawn; Brewer, Karen J. "Design Aspects for the Development of Mixed-Metal Supramolecular Complexes Capable of Visible Light Induced Photocleavage of DNA." Inorg. Chem. 2004, 43, 303-308.
11. Holder, Alvin A.; Stibrany, Robert T.; Bolotina, Nadejda; Hall, Martin; Payne, Vince C.R.; Kirschbaum, Kristin; Pinkerton, A. Alan; Newton Anthony M. "Synthesis and structure of [(nitrito-O,O')bis(di-2-pyridylamine)copper(II)] nitrite." J. Chem. Cryst. 2004, 34, 383-386.
12. Holder, Alvin A. "Chromium, molybdenum, and tungsten." Annu. Rep. Prog. Chem., Sect. A 2005, accepted for publication by the Royal Society of Chemistry.
13. Bakir, M.; Harewood, G.R.; Holder, Alvin; Hassan, I.; Dasgupta, T.; Maragh, P.; Singh-Wilmot, M. "Synthesis, spectroscopic and structural analysis of 5-(4-methylphenyldia-zenyl)salicylaldehyde." Acta Crystallogr. 2005, E61, o1611-o1613.
14. Wilkins, Patricia C.; Johnson, Michael D.; Holder, Alvin A.; Crans, Debbie C. "Reduction of Vanadium(V) by L-Ascorbic Acid at Low and Neutral pH: Kinetic, Mechanistic and Spectroscopic Characterization." Submitted for publication, Inorganic Chemistry.
CHAPTERS IN TEXTBOOKS
1. "NO and NO Donors" Cai, Tingwei Bill; Wang, Peng George; Holder, Alvin A. in "Nitric Oxide Donors for Pharmaceutical and Biological Applications." Wang, Peng George; Cai, Tingwei Bill, Taniguchi, Naoyuki, Eds, Wiley-VCH Verlag GmbH & Co. KgaA., Weinheim, Germany, 2005, Chapter 1, pp. 3-31.
CONFERENCE PRESENTATIONS
1. 205th Spring Meeting of the American Chemical Society, Denver, Colorado, March 28-April 2, 1993. Title: "Oxidation of L-ascorbic acid by the molybdatopentaammine-cobalt(III) ion in aqueous solution." Authors: Alvin A. Holder and Tara P. Dasgupta.
2. 11th Caribbean Conference of Chemistry and Chemical Engineering, St. Augustine, Trinidad and Tobago, March 6-10, 1995. Title: "Kinetics and Mechanism of the Acid Catalysed Hydrolysis of the molybdatopentaamminecobalt(III) ion in aqueous solution." Authors: Alvin A. Holder and Tara P. Dasgupta.
3. 4th International Congress on Chemistry/13th Caribbean Conference on Chemistry and Chemical Engineering, Havana International Conference Center, Cuba, April 16-20, 2001. Title: "The use of Tunicates as Indicators of Water Quality along the North and West Coasts of Barbados." Authors: Harold A.A. Gibbs, Maurice A. Campbell, and Alvin A. Holder.
4. 222nd American Chemical Society National Meeting, Chicago, Illinois, August 26-30, 2001. Title: "Kinetics and Mechanism of the Reaction of S-nitroso-N-acetyl-D,L-penicillamine and Aqueous Sulfite." Authors: Sophia Cheery-Ann Marshall, Alvin A. Holder, and D. Lyn H. Williams.
5. The 23rd Annual American Cancer Society, Virginia Division Seminar on Basic and Clinical Cancer Research, Jordan Hall Conference Center, University of Virginia, Charlottesville, Virginia, March 22, 2003. Title: "Supramolecular Complexes as a New Structural Motif for the Development of a Novel Class of Photodynamic Therapy Agents." Authors: Alvin A. Holder, Shawn M. Swavey, R. Lee Williams, Maria Teresa Tarrago-Trani, Brian Storrie, and Karen J. Brewer.
6. 225th American Chemical Society National Meeting, New Orleans, Louisiana, March 23-27, 2003:
(i) Title: "Mixed-metal supramolecular complexes as DNA photocleavage and photodynamic therapy agents." Authors: Karen J. Brewer, Alvin A. Holder, and Shawn M. Swavey.
(ii) Title: "Mixed-metal supramolecular complexes as photochemical molecular devices and DNA binding and photocleavage agents." Authors: Karen J. Brewer, Alvin A. Holder, R. Lee Williams, Shawn M. Swavey, and Mark Elvington.
7. 226th American Chemical Society National Meeting, New York, New York, September 7-11, 2003:
(i) Title: "Syntheses and Characterisation of Some Oxovanadium(V) Complexes Involving Salicylaldimine-Based Ligands-Attempts To Prepare Insulin Mimicking Compounds." Authors: Gabriel R. Harewood, T. P. Dasgupta, Alvin A. Holder, Xiaoping Tang, William McFarlane, Paul T. Maragh, and Donovan A. Dixon.
(ii) Title: "Syntheses and Characterisation of Some Novel Tetranuclear Copper(II) Complexes Derived From Salicylaldimine-Based Ligands." Authors: Gabriel R. Harewood, T. P. Dasgupta, Alvin A. Holder, Ishmael Hassan, Xiaoping Tang, Paul T. Maragh, Donovan A. Dixon, and Marvadeen A. Singh-Wilmot.
(iii) Title: "Photochemical Properties of Rhodium(III) Centered Triads of Ruthenium(II) and Osmium(II): Uses as Photochemical Molecular Devices and DNA Photocleavage Agents." Authors: Karen J. Brewer, Mark Elvington, Alvin A. Holder, and Shawn M. Swavey.
8. 55th Southeast Regional Meeting of the American Chemical Society, Atlanta, Georgia, November 16-19, 2003:
(i) Title: "Mixed-metal supramolecular complexes and their light activated interactions with biological targets." Authors: R. Williams, Alvin Holder, and Karen Brewer.
(ii) Title: "Supramolecular mixed-metal complexes of ruthenium(II) and rhodium(III)." Authors: Karen Brewer, Mark Elvington, Shawn Swavey, and Alvin Holder.
9. 227th American Chemical Society National Meeting, Anaheim, California, March 28-April 1, 2004:
(i) Title: "Photochemical reactivity of the MMCT states of rhodium(III) centered triads of ruthenium(II) and osmium(II): From photoinitiated electron collection to photodynamic therapy agents." Authors: Karen J. Brewer, Alvin A. Holder, Mark Elvington, and Julie Davenport.
(ii) Title: "Comparison of a series of phenanthrolinequinone thiosemicarbazone compounds." Authors: Richard A. Lawson, Richard T. Mayes, Alvin A. Holder, and Edward C. Lisic.
10. 228th American Chemical Society National Meeting, Philadelphia, Pennsylvania, August 22-26, 2004. Title: "Light induced DNA cleavage and photodynamic therapy properties of MMCT states of rhodium centered supramolecular complexes." Authors: Karen J. Brewer, Alvin A. Holder, Mark Elvington, R. Lee Williams, Jerita Dubash, and Brenda S.J, Winkel.
11. The Fourth International Symposium on Chemistry and Biological Chemistry of Vanadium, September 3-5, 2004, Szeged, Hungary. Title: "A Reinvestigation of the Ascorbic Acid Reduction of Vanadium(V)." Authors: Patricia C. Wilkins, Michael D. Johnson, Alvin A. Holder, and Debbie C. Crans.
12. 229th American Chemical Society National Meeting, San Diego, California, March 13-17, 2005:
(i) Title: "Reinvestigation of the reduction of aqueous vanadium(V) by ascorbic acid: Evidence for both inner and outer sphere pathways." Authors: Michael D. Johnson, Patricia C. Wilkins, Debbie C. Crans, and Alvin A. Holder.
(ii) Title: "An investigative study involving the interaction between the vanadyl cation and NADH in aqueous solution." Authors: Debbie C. Crans, Barbara K. Hughes, and Alvin A. Holder.
13. 47th Rocky Mountain Conference on Analytical Chemistry, Grand Hyatt Denver, Denver, Colorado, July 31-August 4, 2005. Title: "An EPR Study of Reactions of Aqueous Vanadium with NADH." Authors: Alvin A. Holder, Barbara K. Hughes, and Debbie C. Crans.
14. 230th American Chemical Society National Meeting, Washington, D.C., August 28-September 1, 2005:
(i) Title: "AEI: Reactions of Aqueous Vanadium with NADH." Authors: Alvin A. Holder, Barbara K. Hughes, and Debbie C. Crans.
(ii) Title: "The dynamic interaction of the tetrasodium salt of cobalt(II)-4,4',4'',4'''-tetrasulfophthalocyanine (CoTSPc) and its nitrosated analogue, with various S-nitrosothiols and thiols, respectively." Authors: Ross Brown, Tara P. Dasgupta, Paul T. Maragh, and Alvin A. Holder.
(iii) Title: "Syntheses and characterizations of some transition metal complexes containing 2,6-pyridinedicarboxylic acid and various amines." Authors: Vince C.R. Payne, Anthony M. Newton, Tara P. Dasgupta, Paul T. Maragh, Marvadeen A. Singh-Wilmot, Robert T. Stibrany, Kristin, Kirschbaum, Mark R.J. Elsegood, and Alvin A. Holder.
INVITED SEMINAR PRESENTATIONS
02/03: Julius Chambers Biomedical/Biotechnical Research Institute (BBRI), North Carolina Central University, 1801 Fayetteville Street, Durham, NC 27707, U.S.A. Title: "Ligand and Induced Redox Processes-The Molybdenum, Chalcogen, and Nitric Oxide Story."
03/03: Department of Chemistry, Jackson State University, P.O. Box 17910, Jackson, MS 39217, U.S.A. Title: "A Unique Induced Electron Transfer Process Involving NOX Species."
04/03: Department of Chemistry, Hampton University, Hampton, VA 23668, U.S.A. Title: "Reactivity of some Sulfur-Containing Species with NOX Compounds."
EDITORIAL REVIEWER
04/05-present: The Journal of Chemical Education.
COLLABORATIONS
Present Collaborators
(1) Professor Edward I. Stiefel (former Scientific Advisor of Exxon Research & Engineering Company, New Jersey), Department of Chemistry, Princeton University Washington Road & William Street, Princeton, New Jersey 08544, U.S.A.
(2) Professor Tara Dasgupta, Department of Chemistry, University of the West Indies, Mona Campus, Kingston 7, Jamaica.
(3) Dr. Vania Bernardes-Génisson, Faculté des Sciences Pharmaceutiques, Université Paul Sabatier, 35, chemin des Maraîchers, 31062 Toulouse Cedex 04, France.
(4) Professor Karen J. Brewer, Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, U.S.A.
(5) Professor Bruce A. Averill, Department of Chemistry, The University of Toledo, 2801 West Bancroft Street Toledo, Ohio 43606, U.S.A.
(6) Dr. Mark Elsegood, Chemistry Department, Loughborough University, Loughborough Leicestershire, LE11 3TU, U.K.
(7) Professor William McFarlane, Chemistry Department, University of Newcastle, Newcastle upon Tyne, NE1 7RU, U.K.
(8) Professor Chee-Hun Kwak, Head, Department of Chemistry, Sunchon National University, Sunchon, Chonnam, 540-742, Republic of Korea.
(9) Professor Glenn L. Millhauser, Department of Chemistry & Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, U.S.A.
Previous Collaborators
(1) Professor John H. Enemark, Department of Chemistry, University of Arizona, Tucson, Arizona 85721, U.S.A.
(2) Professor A. Geoffrey Sykes, F.R.S., Department of Chemistry, University of Newcastle, Newcastle upon Tyne, NE1 7RU, U.K.
REFERENCES
Available upon request.