The 7th Willem Wijnberg AKC CHF Cancer Fundraiser


For the Results of this Fundraiser
<click here>



The Items for this Very Special Fundraiser were created and donated by Willem Wijnberg,
a very talented artist from The Netherlands.


For the past seven years, Willem has made and donated all of the items for his AKC CHF Cancer Fundraisers.

Thank you, Willem, for your monumental work to fight cancer in our Berners.


To see more of Willem's work and past contributions to our Fundraisers to fight cancer:
<click here>





It's hard to believe that we are holding the 7th annual Willem Wijnberg AKC Canine Health Foundation Cancer Fundraiser (CHF.) Willem Wijnberg is a Dutch artist who works all year to paint Berner items for our annual fundraiser. During the 6 previous fundraisers, we have raised $105,918.04 to support cancer research and the AKC CHF has matched that money at least 1:1, giving us over $212,000 to support the research grants. THANK YOU, Willem, for your wonderful artwork and your dedication to help raise money to fight cancer. THANK YOU all for your very generous donations which helped us raiser this awesome amount! We are ready now to launch our 2009 Willem Wijnberg AKC CHF Cancer Fundraiser.

Researcher Matthew Breen (Professor of Genomics, Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University) is one of the researchers who we have supported in our previous grants. Matthew has been studying malignant histiocytosis and he sent me this note about his current research which we supported and the progress he has made in that research, plus news about a grant he will be submitting for 2010.

Histiocytic malignancies, often referred to as histiocytic sarcoma (HS) and/or malignant histiocytosis (MH) are of major health concern to a variety of breeds, including Bernese Mountain Dog and Flat coated Retriever. As part of CHF-760 Dr. Breen’s lab used sophisticated molecular cytogenetic techniques to evaluate a total of 133 cases of MH/HS from Berners and Flat coated retrievers for genome wide changes in DNA copy number. In this project they identified numerous recurrent DNA copy number that are shared between these two breeds and also aberrations thus far unique to each breed. The regions of the genome recurrently involved have been interrogated and contain several key genes that are known to be associated with the cancer process. The data in this study revealed several key findings:


  • 1) MH/HS from BMDs resident in the USA and in France have recurrent DNA copy number changes that do not differ significantly, suggesting that the strong association between breed and disease type may not be affected by the gene pool of the breed. This indicates that we may be able to consider the BMDs in USA and Europe as a single population. Importantly, as new treatments for this devastating cancer are developed, these data indicate that they likely will apply to all BMDs with MH/HS, regardless of geographic origin.
  • (2) Analysis of histiocytic malignancies from BMDs and FCRs indicates that, in general, there is a gross level of shared genetic changes suggesting that there is a strong association between genomic change and histiocytic malignancies.
  • 3) Of the five most highly recurrent regions that are aberrant in MH/HS, at least three contain genes that already are known to be associated with cancers
  • 4) This study detected numerous aberrant region of the canine genome (on seven different chromosomes) that are significantly associated with the presence of HS affecting either internal organs or just a limb. This association also separated breed (BMD ‘vs’ FCR) and so it is not possible to determine if there is a correlation between 1) breed and cytogenetic profile, or between 2) anatomical location of the MH tumors internal masses and cytogenetic profiles, since there is such a strong association between BMDs and the presence of internal masses. To resolve this we would need to investigate the cytogenetic profiles of other breeds that present with internal MH masses. Further analysis would allow us to determine if it mass location or breed that drives the cytogenetic profiles.
The next phase of this investigation (pending funding) will be to evaluate the status (expression level) of the key genes we have identified, both in affected and unaffected individuals. This will provide further information towards the development of new therapies. Also we intend to introduce additional breeds diagnosed with MH/HS to investigate if the recurrent lesions we have identified are driven by breed or by the malignancy. We anticipate that this next phase will be submitted for consideration during the 2010 call for proposals by AKC-CHF.

Another researcher who we have sponsored by our donations is Elaine Ostrander (head of cancer genetics at the US National Human Genome Research Institute – NHGRI.) Elaine sent me this note about her research on Malignant Histiocytosis earlier today:

"Our preliminary data suggests that the disease in the Bernese and the Flat Coated Retriever are primarily associated with different regions of the genome. Significant progress has been made in narrowing the region of interest for both breeds. We look forward to receiving samples from more eligible dogs.

Malignant histiocytosis (MH) is a disease of great concern for Bernese Mountain Dog (BMD) owners in both the USA and Europe. As a highly breed-specific disorder, 80% of MH cases reported in the USA are in BMDs and 1 in 5 BMDs are likely to succumb to the disease. While MH in the BMD is clearly a genetic disease, the mode of inheritance and the number of genes involved are unknown. The ongoing MH study being conducted in our laboratory attempts to identify the genes and causal mutations for MH in the BMD.

To date we have completed a genome-wide scan for MH associated genes in 240 BMDs from the United States, 140 BMDs from the Netherlands and 94 BMDs from France. By comparing results from all three populations, we have identified loci that are strongly associated with MH. We are now performing candidate gene analysis and fine mapping to search for the causal mutations within these regions that lead to this devastating disease. In parallel a very large and extremely well-characterized French Bernese Mountain Dog family is being genetically studied by the Andre Group in France. These studies provide both confirmation of existing results, as well as new insights.

In addition to the work being done with the BMD, we have conducted our first genome-wide scan in the Flat-coated Retrievers (FCR). FCRs are often diagnosed with a disease similar to MH termed histiocytic sarcoma (HS) that usually presents as a more localized histiocytic cancer. There is much discussion over the distinction between MH and HS, which clinically can be very difficult as they occur in the same constellation of breeds and are both caused by a proliferation of histiocytic cells. The FCR study may lead to the identification of additional regions that contribute to the development of histiocytic cancers. Identification of the genes involved in all histiocytic cancers will lead to more specific diagnostics and improving treatments for these diseases.

The Ostrander Lab would like to thank Berner Lovers, the Bernese Mountain Dog Club of America, the Flat-Coated Retriever Foundation, The Italian Società Italiana Bovaro del Bernese club, Swiss Mountain Dogs International Working Group; The Centre National de la Recherche Scientifique; and the AKC Canine Health Foundation for their generous support of the Malignant Histiocytosis project.

For the AKC CHF Grant Progress Report Review
<click here>

For the update on Dr. Matthew Breen's Grant #760
<click here>


YOU can make a difference. You can do it by making a donation to the 7th Annual Willem Wijnberg AKC CHF Cancer Fundraiser. With your donation you will be helping to support research by both Matthew Breen and Elaine Ostrander, and also by Catherine Andre (CRNS – University of Rennes, France) who is also studying Malignant Histiocytosis in Berners.

With your donation you will get tickets to try to win the various prizes that Willem has made.


.
Joye Neff and Nicky (and Will)
Berner Fundraiser
Mt. Lebanon,
Pittsburgh, PA


Now let's see how much money we can collect. Everyone can participate!! Show your support by sending in your check today!!



Send your U.S. check, payable to "AKC CHF"  to the address below.

Write in the memo line: Berner Lovers' DAF


Please include the following:

  • Name
  • Address
  • Phone Number
  • E-Mail Address
The number of tickets you wish to purchase for each item(s)
(PLEASE include item #s and description!)
Send to:
Joye Neff
1182 Firwood Drive
Pittsburgh, PA 15243-1825

** I can accept foreign cheques with no additional fees to convert the funds to US dollars** 
  **All foreign cheques should be made payable to: Joye M. Neff and sent to me at: Joye M. Neff 1182 Firwood Drive, Pittsburgh, PA 15243-1825.
Donations to the AKC CHF are tax deductible under current U.S. tax laws, however donors should always consult their tax advisors regarding the tax status of their charitable donations.

Please give generously knowing you have a chance to win one of these beautiful items



Challenges!


I am happy to announce that we have two new Challenges to our 7th Annual Willem Wijnberg AKC CHF Cancer Fundraiser!

Bobbie Abern has made a donation to the Cancer Fundraiser and has asked me to use her tickets as a Challenge - Anyone making a donation between $25 and $49.99 will receive 4 free Bonus Challenge Tickets! Pat Long will match these donations up to $250 with her own donation!

So, if you make a donation between $25 and $49.99 not only will you get 4 extra tickets from Bobbie, but Pat will match your donation. The AKC CHF also matches all donations, so you will be getting a double match with your donations!!

We also have two other matches for this fundraiser: Nell Ward and Jean Cheesman will give your 10 free Bonus Tickets when you make a donation of $50 to $99.99. Naor Wallach, Nancy Melone and Joan Corr will give you 30 free Bonus Tickets when you make a donation of $100 or more! !

What a bonanza!! Your donation will get you tickets for the prizes – you might even get bonus tickets AND you are helping the Berners of today and the Berners of the future.



Results!

$14,510.82 is a phenomenal amount of money to raise in 75 days! Can you believe that we actually raised $14,510.82? in our 7th Annual Willem Wijnberg AKC CHF Cancer Fundraiser. Willem works all year painting items for this fundraiser to fight cancer and his hard work and long hours have paid off by the donations received.

THANK YOU, WILLEM, for another spectacular selection of prizes for our fundraiser. You are AWESOME~!

THANK YOU, JEAN CHEESMAN, for making another fantastic website for our fundraiser. The website is a lot of work and you always make sure that the site is attractive and inviting, and helps us raise a lot of money.

THANK YOU to the following Berner Lovers who gave their tickets as Challenges and matched donations to encourage more donations: Bobbie Abern, Jean Cheesman, Joan Corr, Pat Long, Nancy Melone, Naor Wallach, and Nell Ward.



Dates are

November 5th 2009 through January 18th 2010


Tickets are

$1 each ….or

6 for $5….or
30 for $20







Item #1

First Prize!

A blank canvas.

Willem will make a painting of the dog

of the winner of this item.

Winner: Nisha Coons






Item # 2

"Wolle in the Frozen Wood"

owned by Susan Wilkinson

The first ticket drawn will win the actual painting


Then 9 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Tom McKinney

9 Prints – Winners: Annie Bell, Kay Taylor, Marsha Schaublin, Jennifer Kern, Renee Jacquire, Sue Wilkinson (2,) Barb McColgan, Debbie Sharlow









Item #3

"In the Leaves"

owned by Jo Peters

The first ticket drawn will win the actual painting


Then 7 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Jo Peters

7 Prints – Winners: Bhavya Heiny, Renee Jacquire, Annie Bell (2,) Linda Adams, Jo Peters, Stan Smith





Item #4

Painting of Nora

owned by Toby Earlichman


.The first ticket drawn will win the actual painting


Then 7 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Cookie Silvestri

7 Prints – Winners: Glenda Peirce, Toby Erlichman (2,) Cookie Silvestri, Alise Burbridge, Annie Bell, Jennifer Kern






Item #5

Painting of Sanford the BARC Dog

The first ticket drawn will win the actual painting


Then 8 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Annie Bell

8 Prints – Winners: Marsha Schaublin, Jennifer Kern, Linda Adams (2,) Georgiana Webber, Nicole O’Brien, Isa Friend, Lea Mehrkens







Item #6

Painting of Cheryl Thornton's BARC dog, Mikki


The first ticket drawn will win the actual painting

Then 8 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Cathi Dovico

8 Prints – Winners: Lisa Hawes, Janet French, Cheryl Thornton (2,) Jennifer Kern, Patty Wellinger, Annie Bell, Linda Adams






Item #7

Painting of Willes Bear the BARC dog


The first ticket drawn will win the actual painting

Then 8 additional tickets will be drawn and each winner will get a print of this painting


Winner: Jo Peters

8 Prints – Winners: Sal & Cherie Massaro, Jennifer Kern, Karen Thompson, Linda Adams, Donna Wiles, Jo Peters, Annie Bell, Patti Small & Diane Smith



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Item #8

Painting of Cassy the BARC dog


The first ticket drawn will win the actual painting

Then 8 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Tom McKinney

8 Prints – Winners: Kim Moran, Terri Babcock, Heidi Henderson, Marian Bragdon, Patti Grijalva, Jennifer Kern, Patty Wellinger, Marsha Schaublin







Item #9

Painting of Ariel and Friend,

Ariel is a BARC dog

The first ticket drawn will win the actual painting

Then 7 additional tickets will be drawn and each winner will get a print of this painting


Winner: Diane Meslinski

7 Prints – Winners: Diane Smith & Patty Small, Annie Bell, Gina Sappenfield, Jennifer Kern, Patty Wellinger, Marsha Schaublin, Sal & Cherie Massaro








Item #10

Painting of Clover
the BARC dog

The first ticket drawn will win the actual painting

Then 8 additional tickets will be drawn and each winner will get a print of this painting


Winner: Annie Bell

8 Prints – Winners: Stan Smith, Linda Adams (2,) Jennifer Kern, Pat Douglass, Annie Bell (2,) Georgiana Webber





Item #11

Painting of Delilah Muth
the BARC dog

The first ticket drawn will win the actual painting

Then 7 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Terri Babcock

7 Prints – Winners: Nancy Bard, Sal & Cherie Massaro, Coral Denis, Patty Gartmann, Dawn Flaherty, Pat Douglass, Dawn Weber







Item #12

Painting of Alexis Smith's Duke


The first ticket drawn will win the actual painting

Then 7 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Tom McKinney

7 Prints – Winners: Sheila Durfee, Alexis Smith, Janet French, Marian Bragdon, Karen Thompson, Sal & Cherie Massaro, Linda Adams






Item #13

Painting of Janice Parky's BARC dog, Halley


The first ticket drawn will win the actual painting

Then 20 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Janice Parky

20 Prints – Winners: Annie Bell, Donna Wiles, Janice Parky (2,) Julian Jess, J. Jenkin , Linda Adams (2,) Jennifer Kern, Mont Cape, Liz Caldwell, BARC Fundraiser (9)






Item #14

Painting of Cleo the
BARC dog

The first ticket drawn will win the actual painting

Then 7 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Linda Adams

7 Prints – Winners: Lisbeth Plant, Julie Greco, Jennifer Kerns, Annie Bell (2,) Marsha Schaublin, Linda Adams






Item #15

Prints of Willem's Family Portrait


8 tickets will be drawn and each winner will get a print of this painting.


Winners: Lisa Baldwin, Stephanie Biksacky, Annie Bell, Diane Smith & Patti Small, Coral Denis, Kathy Sibley, Donna Wiles, Audrey Donovan







Item #16

Painting of Emiel


owned by Clair Magee

The first ticket drawn will win the actual painting

Then 8 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Pat Tackett

8 Prints – Winners: Sue Wilkinson, Linda Adams, Annie Bell (2,) Pat Tackett, Lisbeth Plant, Jennifer Kern, Sherri Starbird







Item #17

Painting of an unknown
BARC puppy

The first ticket drawn will win the actual painting

Then 7 additional tickets will be drawn and each winner will get a print of this painting.


Winner: Tom McKinney

7 Prints – Winners: Karen Thompson, Annie Bell, Randy Gaines, Renee Jacquier, Ellie Kittler, Jennifer Kern, Liz Caldwell




Item #18.

8 prints of the painting of

Patti Finley’s, Missy

8 tickets will be drawn and each winner will get a print of this painting.


Winners: Kathy Sibley, Georgiana Webber, Annie Bell (2,) Linda Adams (2,) Patti Finley, Jean Smith





Item #19

Oval medallion for a necklace


with Berner and golden edge

Winner: Linda Adams


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Item #20

Oval medallion for a necklace


with Berner and golden edge

Winner: Linda Adams





Item #21

Oval medallion for a necklace


with Berner and golden edge

Winner: Lori Jacobson





Item #22

Oval medallion for a necklace


with Berner and golden edge

Winner: Carol McArthur





Item #23

Oval medallion for a necklace


with Berner and golden edge

Winner: Lori Jacobson





Item #24

Oval medallion for a necklace


with Berner and golden edge

Winner: Ellie Kittler





Item #25

Oval medallion for a necklace


with Berner and golden edge

Winner: Linda Adams





Item #26

Oval medallion for a necklace


with Berner and golden edge

Winner: Ellie Kittler





Item #27

Oval medallion for a necklace


with Berner and golden edge

Winner: Fara Bushnell





Item #28

Oval medallion for a necklace


with Berner and golden edge

Winner: Donna Wiles





Item #29

Oval medallion for a necklace


with Berner and golden edge

Winner: Alice Gordon





Item #30

Service plate


with Berner and golden edge

Winner: Dottie Schulte





Item #31

Service plate


with Berner and golden edge

Winner: Valerie Chase





Item #32

Service plate


with Berner and golden edge

Winner: Sherri Starbird





Item #33

Wall plate


with Berner and golden edge

Winner: Michelle Ryan





Item #34

Candy plate


with Berner and golden edge

Winner: Signe Strawser





Item #35

Candy plate


with Berner and platinum edge

Winner: Annie Barton





Item #36

Candy plate


with Berner and platinum edge

Winner: Patti Rosner





Item #37

Candy plate


with Berner and platinum edge

Winner: Carol McArthur






Item #38

Framed oval china pendant with Berner


Winner: Linda Adams







Item #39

Framed oval china pendant with Berner


Winner: Marsha Schaublin






Item #40

Framed oval china pendant with Berner


Winner: Pat Tackett






Item #41

Framed oval china pendant with Berner


Winner: Linda Adams






Item #42

Little china heart with Berner head


Winner: Linda Adams


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Item #43

Little china heart with Berner head


Winner: Denise Taylor





Item #44

Little china heart with Berner head


Winner: Nancy Bard





Item #45

Little china heart with Berner head


Winner: Gina Sappenfield





Item #46

Little china heart with Berner head


Winner: Linda Adams


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Item #47

Little china heart with Berner head


Winner: Linda Adams





Item #48

Jewelry box


Winner: Carol McArthur





Item #49

Heart ornament

for the Christmas Tree

Winner: Teresa Godfrey





Item #50

Heart ornament

for the Christmas Tree

Winner: Jennifer Kern



Item #51

Heart ornament

for the Christmas Tree

Winner: Annie Barton





Item #52

Heart ornament

for the Christmas Tree

Winner: Shirley Bartmess





Item #53

Heart ornament

for the Christmas Tree

Winner: Teresa Godfrey





Item #54

Wine Glass


Winner: Joni Payne





Item #55

Wine Glass


Winner: Jacque Spiezer





Item #56

Wine Glass


Winner: Sal & Cherie Massaro





Item #57

Crab Cocktail Glass


Winner: Linda Adams





Item #58

China basket


Winner: Gina Sappenfield





Item #59

China basket


Winner: Linda Adams





Item #60

China basket


Winner: Helen Hayes





Item #61

Small oval China plate


Winner: Murray Johnston





Item #62

Small oval China plate


Winner: Linda Adams





Item #63

Small oval China plate


Winner: Kerry Batting





Item #64

Small oval China plate


Winner: Lori Jacobsen





Item #65

Small oval China plate


Winner: Linda Adams





Item #66

Small oval China plate


Winner: Linda Adams


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Item #67

Small oval China plate


Winner: Linda Adams


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Item #68

Small oval China plate


Winner: Carol McArthur





Item #69

Small oval China disc


Winner: Liz Caldwell





Item #70

Small oval China disc


Winner: Carol McArthur





Item #71

Small oval China disc


Winner: Patti Rosner





Item #72

Small oval China disc


Winner: Janet French





Item #73

Small oval China disc


Winner: Marsha Schaublin





With special thanks to Took Visudtibhan who kindly donated china for Willem to create many of these wonderful items


And here is a very special picture,

Willem at work on Amika's painting
for our Angel Pin Lady, Karen Connors,
We love you!
!!!!

Willem at work

Histio Roll Call
for our too many Berners lost to Malignant Histiocytosis

Shelley's Histio Website
for other breeds lost to this awful cancer

Endlesslove Angels
for all breeds and species lost to all types of cancer

Canine Cancer Information Page
for all aspects of cancer care



By donating to this Fundraiser you are helping with research which in the future will help spare the pain of losing a loved one to Cancer!



Website hosted by http://bernese.biz mail jean.cheesman@lineone.net