Phentermine is the most commonly prescribed prescription appetite suppressant, accounting for 50% of the prescriptions. Part of this reason is because it's significantly cheaper than the other major FDA-approved diet drugs, Meridia and Xenical.
Phentermine first received approval from the Food and Drug Administration (FDA) in 1959 as an appetite suppressant for the short-term treatment of obesity.
Phentermine resin became available in the United States in 1959 and Phentermine Hydrochloride in the early 1970s.
In the US, Phentermine is currently sold under the brand names Ionamin® (Medeva Pharmaceuticals) and Adipex-P® (Gate Pharmaceuticals). It is also available as a generic medication, known as 'phentermine'.
Previously, it was sold under the name Fastin® (formerly produced by King Pharmaceuticals for SmithKline Beecham). In December 1998, SK-Beecham withdrew Fastin from the market.
As Phentermine is an older drug, no new efficacy trials have been conducted. The one notable exception, are several trials on the combination of Phentermine and Fenfluramine in the early and mid 1990s.
Oral Phentermine Hydrochloride (HCL) is sold for weight loss. It is in the Sympathomimetic family of appetite suppressants (used for the short-term management of exogenous obesity.) When used in conjunction with diet, exercise, and behavior therapy, Phentermine may help you to lose weight while you are learning new ways to eat and to exercise.
Phentermine works by stimulating the hypothalamus gland and affecting certain neurotransmitters to decrease appetite. The hypothalamus is the region of the brain that controls the autonomic nervous system, regulating sleep cycles, body temperature, appetite, etc.
Take Phentermine ONLY as directed by your doctor.
Do NOT take more of it
Do NOT take it more often, and
Do NOT take it for a longer time than your doctor ordered.
If too much Phentermine is taken, it may cause unwanted effects or become habit-forming.
Please speak with your doctor if you think that Phentermine is not working properly after you have taken it for a few weeks. DO NOT increase the dose.
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