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1: J Thorac Cardiovasc Surg  2002 Mar;123(3):498-501

 

Anatomic variations of the T2 nerve root (including the nerve of Kuntz) and

their implications for sympathectomy.

 

Chung IH, Oh CS, Koh KS, Kim HJ, Paik HC, Lee DY.

 

Departments of Anatomy and Thoracic and Cardiovascular Surgery, Yonsei

University College of Medicine, Seoul, Korea, the Department of Anatomy,

Sungkyunkwan University School of Medicine, Suwon, Korea, the Department of

Anatomy, Medical College, Konkuk University, Chungju, Korea, and the Department

of Oral Biology, Yonsei University College of Dentistry, Seoul, Korea.

 

OBJECTIVE: The aim of this study was to clarify the anatomic variations of the

intrathoracic nerve of Kuntz, and this should help delineate the resection

margins during video-assisted thoracic sympathectomy. METHODS: Sixty-six

thoracic sympathetic chains of 39 adult Korean cadavers were dissected on both

sides of the thorax in 27 cadavers (54 sides) and on one side in 12 cadavers (12

sides). RESULTS: The intrathoracic nerve was observed in 45 (68.2%) sides and

was present bilaterally in 48.1% of cadavers. No intrathoracic nerve or

ascending ramus communicans arising from the second thoracic nerve was observed

in only 5 (7.6%) sides. The diameter of the intrathoracic nerve was 1.25 plus

minus 0.55 mm on average. The arising point of the intrathoracic nerve from the

second thoracic nerve was 7.3 mm on average from the sympathetic trunk. Presence

of the stellate ganglion was noted in 56 (84.8%) sides, and 6 (9.1%) sides

showed a single large ganglion formed by the stellate and the second thoracic

sympathetic ganglia. The second thoracic sympathetic ganglion was most commonly

located (50%) in the second intercostal space. CONCLUSION: The anatomic

variations of the intrathoracic nerve of Kuntz and the second thoracic

sympathetic ganglion were characterized in human cadavers. It is hoped that this

study will help to improve the recurrence of symptoms caused by the

intrathoracic nerve in an upper thoracic sympathectomy for hyperhidrosis.

 

PMID: 11882821 [PubMed - as supplied by publisher]

 

 

 

2: J Vasc Surg  2002 Feb;35(2):382-6

 

Palmar hyperhidrosis: Evidence of genetic transmission.

 

Ro KM, Cantor RM, Lange KL, Ahn SS.

 

University of California at Davis School of Medicine, the Department of Human

Genetics, University of California at Los Angeles School of Medicine, and the

UCLA Center for the Health Sciences, Division of Vascular Surgery.

 

BACKGROUND: Primary palmar hyperhidrosis is a condition marked by excessive

perspiration and is reported to have an incidence of 1% in the Western

population. It is a potentially disabling disorder that interferes with social,

psychological, and professional activities. Over the past several years, several

investigators have reported a positive family history in their patients treated

for hyperhidrosis. To date, the cause is unknown; furthermore, epidemiologic

data are scarce and inadequate. METHODS: To characterize the genetic

contribution to hyperhidrosis, we conducted a prospective study of 58

consecutive patients with palmar, plantar, or axillary hyperhidrosis treated

with thoracoscopic sympathectomy from September 1993 to July 1999. Forty-nine of

the 58 probands volunteered family history data for these analyses (84% response

rate). A standardized questionnaire was administered during the postoperative

visit or by phone interview, and a detailed family history was obtained. The

same questionnaire was also administered to a set of 20 control patients. The

familial aggregation of hyperhidrosis has been quantified by estimating the

recurrence risks to the offspring, parents, siblings, aunts, uncles, and cousins

of 49 probands and 20 controls. We estimated the penetrance by use of a genetic

analysis program. RESULTS: Thirty-two of 49 (65%) reported a positive family

history in our hyperhidrosis group, and 0% reported a positive family history in

our control group. A recurrence risk of 0.28 in the offspring of probands

compared with frequency of 0.01 in the general population provides strong

evidence for vertical transmission of this disorder in pedigrees and is further

supported by the 0.14 risk to the parents of the probands. The results indicate

that the disease allele is present in about 5% of the population and that one or

two copies of the allele will result in hyperhidrosis 25% of the time, whereas

the normal allele will result in hyperhidrosis less than 1% of the time.

CONCLUSIONS: We conclude that primary palmar hyperhidrosis is a hereditary

disorder, with variable penetrance and no proof of sex-linked transmission.

However, this does not exclude other possible causes, and we anticipate that

genetic confirmation of this disorder may lead to earlier diagnoses and advances

in medical and psychosocial interventions.

 

PMID: 11854739 [PubMed - in process]

 

 

 

3: Neurosurgery  2002 Feb;50(2):306-11; discussion 311-2

 

Biportal thoracoscopic sympathectomy: surgical techniques and clinical results

for the treatment of hyperhidrosis.

 

Han PP, Gottfried ON, Kenny KJ, Dickman CA.

 

Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's

Hospital and Medical Center, Phoenix, Arizona 85013-4496, USA.

 

OBJECTIVE: To describe a bilateral thoracoscopic sympathectomy procedure, using

a biportal approach, for the treatment of severe hyperhidrosis. METHODS: Between

May 1996 and September 2000, 103 consecutive patients underwent thoracoscopic

sympathectomy procedures to treat bilateral hyperhidrosis (206 procedures).

Operative results, complications, and patient satisfaction were determined by

reviews of hospital and office charts and by follow-up assessments in the

outpatient clinic. Long-term results were determined with clinical examinations,

follow-up office visits, and follow-up questionnaires. RESULTS: Ninety-three

patients presented with primary palmar hyperhidrosis, eight with primary

axillary hyperhidrosis, and two with primary craniofacial hyperhidrosis. Rates

of complete resolution in the primary area affected were 100% in palmar and

craniofacial cases and 75% in axillary cases. The average length of

hospitalization was 1.06 days, and 96 patients (93.2%) were discharged on or

before the end of the first postoperative day. Of 59 patients (57.3%) who

developed compensatory hyperhidrosis, only 11 patients (10.7%) reported that it

was bothersome and none considered it disabling. All postoperative complications

were transient; five patients experienced unilateral Horner's syndrome, three

patients experienced intercostal neuralgia, and two patients required a chest

tube after surgery because of a pneumothorax. CONCLUSION: Thoracoscopic

sympathectomy using a biportal approach effectively treats hyperhidrosis and is

associated with short hospital stays, high patient satisfaction rates, and low

rates of compensatory hyperhidrosis or other complications.

 

PMID: 11844265 [PubMed - in process]

 

 

 

4: Eur J Cardiothorac Surg  2002 Jan;21(1):67-70

 

Minimally invasive video-endoscopic sympathectomy by use of a transaxillary

single port approach.

 

Lardinois D, Ris HB.

 

Division of Thoracic Surgery, University Hospital, Inselspital, Bern,

Switzerland. didier.lardinois@chi.usz.ch

 

OBJECTIVES: This is a prospective study to evaluate the long-term outcome and

the value of a transaxillary single port thoracic sympathectomy by use of a

modified paediatric cystoresectoscope in a consecutive series of patients with

facial blushing and/or hyperhidrosis. MATERIALS AND METHODS: All patients who

underwent a thoracic transsection of the sympathetic chain from T2 to T5 by use

of a 7-mm single port approach and a modified urologic electroresectoscope

between 1996 and 1998 were prospectively analysed regarding postoperative

morbidity and outcome (clinical evaluation, visual analogue scale) in order to

validate this technique. RESULTS: 37 patients (18 men, 19 women) with an age

ranging from 18 to 67 years (mean 34 years) underwent 74 bilateral

video-assisted thoracic sympathectomies. The indications for sympathectomy

included facial blushing in 32%, hyperhidrosis in 52%, or both in 16% of the

patients. Ninety-five percent of the patients were discharged from the hospital

on the next day, the 30-day mortality was zero, and there was no conversion to

an open procedure. A severe complication with crossed emboli and motor aphasia

was noted. A unilateral transient Horner's syndrome was observed in two

patients. Three-month follow-up revealed an excellent cosmetic and functional

result, with no residual pain. Complete relief of symptoms was observed in 89%

and in 100% of the patients with facial blushing and palmar hyperhidrosis,

respectively, after a follow-up of 34.5 months. Recurrence of the symptoms after

initial regression was noted in 5.7% of the patients 3 years after surgery.

Compensatory sweating of the lower extremities was significantly increased in

patients with hyperhidrosis and facial blushing; however, sweating of the trunk

was only increased in patients with hyperhidrosis. Improvement of quality of

life was observed in 94.6% of the patients. CONCLUSIONS: Single port

thoracoscopic sympathectomy by use of a modified paediatric cystoresectoscope

and transsection from T2 to T5 gives an excellent cosmetic and functional

outcome, with better results in patients with hyperhidrosis.

 

PMID: 11788259 [PubMed - indexed for MEDLINE]

 

 

 

5: J Neurosurg  2002 Jan;96(1 Suppl):68-72

 

Anatomical location of T2-3 sympathetic trunk and Kuntz nerve determined by

transthoracic endoscopy.

 

Wang YC, Sun MH, Lin CW, Chen YJ.

 

Department of Neurosurgery, Taichung Veterans General Hospital, Taiwan, Republic

of China. ycwang@vghtc.vghtc.gov.tw

 

OBJECT: Bilateral subaxillary transthoracic endoscopic sympathectomy (TES) is a

popular procedure of upper thoracic sympathectomy. The anatomical locations of

the T-2 and T-3 sympathetic trunks, as viewed under the endoscope, are varied in

the rib head areas. In this study, the authors investigated the more visible

anatomical locations of the T-2 and T-3 sympathetic trunks, the so-called nerves

of Kuntz, and intercostal rami by performing transthoracic endoscopy. METHODS:

Seventy patients with palmar hyperhidrosis undergoing bilateral TES (140 sides)

via the anterior subaxillary approach were included in this study. The operative

findings and video images of the T-2 and T-3 sympathetic trunks and ganglia were

recorded and analyzed. The anatomical locations of the T-2 and T-3 sympathetic

trunks along the horizontal axes of the rib heads were determined using a

three-region system constructed by the authors. The area between the rib neck

and the medial border of the rib head was equally divided into Region E

(external half) and Region M (medial half). The area between the medial border

of the rib head and the paravertebral ligament was defined as Region I. The

incidence of the T-2 and T-3 sympathetic trunks found in Regions E, M, and I

were 31.4 to 42.9%, 50 to 57.1%, and 7.1 to 11.4%, respectively, on the left

side, and 24.3 to 34.3%, 57.1 to 65.7%, and 8.6 to 10%, respectively, on the

right side. One right (1.4%) and six left (8.6%) Kuntz nerves originating from

the T-3 sympathetic trunk were found in seven patients (10%). The intercostal

ramus was found around the T-2 rib neck in 24 patients (34.3%), with 18 cases

(25.7%) for each side. The intercostal ramus around the T-3 rib neck was found

in 17 patients (24.3%): 12 (17.1%) on the right and nine (12.9%) on the left.

CONCLUSIONS: These results indicate that approximately 90% of the T-2 or T-3

sympathetic trunks are located on the rib head. These findings may also be used

to assist the surgeon in fluoroscopic guidance for locating the T-2 and T-3

sympathetic trunks during posterior percutaneous sympathectomy.

 

PMID: 11795717 [PubMed - indexed for MEDLINE]

 

 

 

6: J Egypt Soc Parasitol  2001 Dec;31(3):835-42

 

Thoracoscopic sympathectomy for treatment of hyperhidrosis surgical experience

and results of 30 cases.

 

Helmy MA, Ahmed HA, Allam MF.

 

Department of General Surgery, Faculty of Medicine, Ain Shams University, Cairo,

Egypt.

 

The thoracoscopic sympathectomy in treatment of primary palmar and axillary

hyperhidrosis was performed on 30 patients complaining of hyperhidrosis admitted

to El Demerdash University Hospital and Ain Shams University Specialised

Hospital and The Saudi German Hospital between March 1999 and March 2001. The

indication of surgery was primary palmar hyperhidrosis in 24 cases and combined

palmar and axillary hyperhidrosis in 6 cases. 25 cases were males and 5 cases

were females. The mean age in our sample was 25.7 +/- 4.05 years. There were no

major complications in our series and 4 cases were complicated by intercostal

vessels bleeding which were successfully controlled by cauterization during

surgery and no one of them necessitated neither thoracotomy nor application of

intercostal tubes. The patients were followed up for one year after operation

and only one case had recurrence of palmar hyperhidrosis.

 

PMID: 11775109 [PubMed - in process]

 

 

 

7: Ann Thorac Surg  2001 Nov;72(5):1801-2

 

Video thoracoscopic sympathectomy with intraoperative monitoring of palmar skin

temperature for palmar hyperhidrosis.

 

Kao MC.

 

Publication Types:

Letter

 

PMID: 11722112 [PubMed - indexed for MEDLINE]

 

 

 

8: J Clin Neurosci  2001 Nov;8(6):539-41

 

Thoracoscopic sympathectomy for palmar hyperhidrosis: effects on pulmonary

function.

 

Tseng MY, Tseng JH.

 

Division of Neurosurgery, Department of Surgery, Medical School and Hospital,

National Taiwan University, 7 Chung-Shan South Road, Taipei, Taiwan, R.O.C.

tmy59100@ms4.hinet.net

 

Palmar hyperhidrosis, probably caused by an over-reactivity of sympathetic

nerves passing through the second and the third thoracic sympathetic ganglia (T2

& T3 ganglia), can only be cured by sympathectomy. Such sympathetic denervation

may also alter pulmonary function. Previous studies have shown that open

sympathectomy can cause significant deterioration in pulmonary function,

however, the surgical procedure itself may contribute to the change. Recently

thoracoscopic sympathectomy has been developed as a minimally invasive but

effective treatment for palmar hyperhidrosis. In order to investigate the effect

of sympathectomy, pulmonary function was compared before and four weeks after

operation in 20 patients. Forced vital capacity (FVC) (-2.3%), forced expiratory

volume in one second (FEV1) (-6.1%), and FEV1/FVC (-4.6%) were all slightly but

significantly decreased four weeks after thoracoscopic sympathectomy. Also the

instantaneous forced expiratory flow at 75%, 50% and 25% of the FVC (Vmax25,

Vmax50, Vmax75) in flow-volume curves were decreased (-1.6%, -8.4%, and -20%

respectively). Therefore, thoracoscopic sympathectomy minimises pulmonary

restrictive effects but allows subclinical small airway obstructive effects to

become more evident.

 

PMID: 11787462 [PubMed - indexed for MEDLINE]

 

 

 

9: J Clin Neurosci  2001 Nov;8(6):555-6

 

Endoscopic extraperitoneal lumbar sympathectomy for plantar hyperhidrosis: case

report.

 

Tseng MY, Tseng JH.

 

Division of Neurosurgery, Department of Surgery, Medical School and Hospital,

National Taiwan University, 7 Chung-Shan South Road, Taipei 100, Taiwan, R.O.C.

 

A right sided endoscopic retroperitoneal lumbar sympathectomy was performed on a

23 year old female who had plantar hyperhidrosis. After the operation, the right

foot temperature increased and the plantar hyperhidrosis was relieved. During

the follow up period, both feet were warm and dry, although only the right side

lumbar sympathectomy had been performed. The outcome appeared to be compatible

with that of an open procedure but with minimal invasiveness. Copyright 2001

Harcourt Publishers Ltd.

 

Publication Types:

Technical Report

 

PMID: 11683604 [PubMed - indexed for MEDLINE]

 

 

 

10: Lakartidningen  2001 Oct 10;98(41):4494-5

 

[Sympathectomy--how much side-effects are acceptable?]

 

[Article in Swedish]

 

Berglund F, Berglund E.

 

Publication Types:

Letter

 

PMID: 11699265 [PubMed - indexed for MEDLINE]

 

 

 

11: Auton Neurosci  2001 Oct 8;93(1-2):91-4

 

Transthoracic endoscopic T-2, 3 sympathectomy for facial hyperhidrosis.

 

Chen HJ, Lu K, Liang CL.

 

Department of Neurosurgery, Chang Gung University and Memorial Hospital at

Kaohsiung, Kaohsiung Hsien, Taiwan. chenmd@ms8.hinet.net

 

Twenty-five patients (20 men and 5 women) with the chief complaint of facial

hyperhidrosis were treated by transthoracic endoscopic T-2, 3 sympathectomy. All

patients were essentially in good health except the embarrassment of facial

sweating. Fifteen of them also suffered from distressing palmar hyperhidrosis.

The ages ranged from 18 to 40 years (mean age 25 years). All of them except two

obtained a satisfactory improvement of facial hyperhidrosis after 3 months to 2

years of follow-up. One man demonstrated very mild ptosis in the right eye. Pre-

and postoperative sympathetic skin response (SSR) revealed the absence rate from

20% to 72% with electrical stimulation (p < 0.05). This study shows that T-2, 3

sympathectomy is a choice of treatment for facial hyperhidrosis and sympathetic

supply to the face may at least partly be from T-2, 3 level.

 

PMID: 11695712 [PubMed - in process]

 

 

 

12: Arch Surg  2001 Oct;136(10):1115-7

 

Experiences in thoracoscopic sympathectomy for axillary hyperhidrosis and

osmidrosis: focusing on the extent of sympathectomy.

 

Hsu CP, Shia SE, Hsia JY, Chuang CY, Chen CY.

 

Division of Surgical Emergency, Taichung Veterans General Hospital, Building

160, Section 3, Taichung-Kang Road, Taichung, Taiwan. cliff@vghtc.vghtc.gov.tw

 

HYPOTHESIS: A more selective sympathectomy can improve the outcome of axillary

hyperhidrosis and osmidrosis and minimize the potential sequelae. DESIGN:

Retrospective cohort. SETTING: Tertiary care center. PATIENTS: Between July 1,

1996, and May 30, 2000, 171 patients with axillary hyperhidrosis and osmidrosis

were studied. INTERVENTIONS: T3-4 sympathectomies were performed in 40 patients

(group 1), T4 sympathectomies were performed in 56 patients (group 2), and T4-5

sympathectomies were performed in 75 patients (group 3). MAIN OUTCOME MEASURES:

The surgical outcomes were evaluated by direct patient interview in the

outpatient clinic or by telephone or mail questionnaires. The results were

categorized as excellent (significant or complete disappearance of symptoms),

good (>/=50% improvement), or poor (<50% improvement). RESULTS: There were no

surgical mortalities in this study. Twenty-eight group 1 patients (70%), 16

group 2 patients (29%), and 22 group 3 patients (29%) developed compensatory

perspiration (P<.001). Six group 1 patients (15%), 1 group 2 patient (2%), and 1

group 3 patient (1%) developed dry hands (P =.02). In the group 1 patients, the

surgical outcomes were excellent in 21 (52%), good in 6 (15%), and poor in 13

(32%). In the group 2 patients, the surgical outcomes were excellent in 29

(52%), good in 10 (18%), and poor in 17 (30%). In the group 3 patients, the

surgical outcomes were excellent in 53 (71%), good in 11 (15%), and poor in

11(15%) (P =.04). (Percentages may not sum to 100 because of rounding.)

CONCLUSION: T4-5 sympathectomies provide higher patient satisfaction rates in

treating axillary hyperhidrosis and osmidrosis, with fewer sequelae.

 

PMID: 11585501 [PubMed - indexed for MEDLINE]

 

 

 

13: Surg Endosc  2001 Oct;15(10):1159-62

 

Prevention of compensatory hyperhidrosis after thoracoscopic sympathectomy for

hyperhidrosis.

 

Riet M, Smet AA, Kuiken H, Kazemier G, Bonjer HJ.

 

Department of Surgery, Erasmus University Medical Center, Rotterdam, The

Netherlands.

 

BACKGROUND: Compensatory hyperhidrosis is a troublesome complication of

thoracoscopic sympathectomy for hyperhidrosis. After extensive resection of the

second through the fourth ganglion (T2-4), as well as after limited resection of

the second ganglion (T2), the reported incidence of compensatory hyperhidrosis

ranges as high as 50-97%. The purpose of this study was to determine whether the

incidence of compensatory hyperhidrosis can be reduced by limiting the

thoracoscopic sympathectomy to another level, the third ganglion. METHODS: We

analyzed 28 thoracoscopic sympathectomies for palmar and/or axillary

hyperhidrosis. In all patients, the sympathetic chain was transected cranially

and caudally to the third ganglion (T3 dissection). Long-term follow-up was

conducted by interviewing patients using standardized questionnaires. RESULTS:

The surgery was effective in all patients. After a median follow-up of 3.5

years, compensatory hyperhidrosis was not recorded in any of the patients. There

were no recurrences of hyperhidrosis. CONCLUSION: Limited thoracoscopic

sympathectomy at the level of the third ganglion is effective and seems to

prevent compensatory hyperhidrosis.

 

PMID: 11727092 [PubMed - in process]

 

 

 

14: Ann Thorac Surg  2001 Sep;72(3):895-8

 

Video-assisted thoracoscopic "resympathicotomy" for palmar hyperhidrosis:

analysis of 42 cases.

 

Lin TS.

 

Division of General Thoracic Surgery, Changhua Christian Hospital, Chung Shan

Medical and Dental College, Taichung, Taiwan, Republic of China.

lin8065@ms14.hinet.net

 

BACKGROUND: There are rare reports of video-assisted thoracoscopic

resympathicotomy for patients with palmar hyperhidrosis. I present our

experience in treating a persistent or recurrent palmar hyperhidrosis after

primary endoscopic sympathectomy or sympathicotomy and discuss the perioperative

management. METHODS: We reoperated on 42 patients using a technique of

video-assisted thoracoscopic resympathicotomy. All patients were placed in a

semi-sitting position under single- or double-lumen intubated anesthesia. An

8-mm, 0 degrees thoracoscope was used to interrupt the nerve conduction to the

palms from the T2 and T3 ganglia, through one or two 0.8-cm subaxillary

incisions. RESULTS: The reasons for failure of endoscopic sympathectomy or

sympathicotomy in 26 patients included pleural adhesion (15 of 26, 57.7%),

incorrect identification of T2 ganglion (3 of 26, 11.5%), vessel overriding or

close to sympathetic nerve (3 of 26, 11.5%), incomplete interruption of

sympathetic nerve (2 of 26, 7.7%), medially located sympathetic nerve (2 of 26,

7.7%), and aberrant venous arch (1 of 26, 3.8%). The causes of recurrent palmar

hyperhidrosis after primary transthoracic endoscopic sympathicotomy or

sympathectomy (TES) in 16 patients included a possible effect of T3 ganglion (8

of 16, 50%), Kuntz fiber (3 of 16, 18.8%), nerve regeneration (3 of 16, 18.8%),

and incomplete interruption of T2 ganglion (2 of 16, 12.5%). Surgical

complications included pneumothorax (1 patient, 2.4%), hemothorax (1 patient,

2.4%), and compensatory sweating (36 patients, 86%). All patients had obtained

successful bilateral sympathectomies and had satisfactory results after a mean

of 32.1 months of follow-up. CONCLUSIONS: Video-assisted thoracoscopic

resympathicotomy is an effective and safe method for a previously unsuccessful

sympathectomy or recurrent palmar hyperhidrosis if the surgeon acknowledges

possible anatomic variations and can overcome the problems related to pleural

adhesions.

 

PMID: 11565677 [PubMed - indexed for MEDLINE]

 

 

 

15: J Thorac Cardiovasc Surg  2001 Sep;122(3):633-4

 

Needlescopic surgery for palmar hyperhidrosis.

 

Kao MC.

 

Publication Types:

Letter

 

PMID: 11547332 [PubMed - indexed for MEDLINE]

 

 

 

16: Neurosurgery  2001 Sep;49(3):628-34; discussion 634-6

 

A new mode of percutaneous upper thoracic phenol sympathicolysis: report of 50

cases.

 

Wang YC, Wei SH, Sun MH, Lin CW.

 

Department of Neurosurgery, Taichung Veterans General Hospital, Taiwan, Republic

of China. ycwang@vghtc.vghtc.goc.tw

 

OBJECTIVE: Our previous study demonstrated that a high concentration of phenol

(75-90%) with minimal volume (0.02 ml) can elicit serious degeneration of

ganglion cells of the stellate ganglia in cats. Another previous study in our

clinical patients demonstrated that approximately 84 to 90% of the upper

thoracic (T2-T3) sympathetic trunks can be found under an endoscope on the

ventral side of the T2-T3 rib heads. In this report, we present a new mode of

dorsal percutaneous thoracic phenol sympathicolysis (PTPS) for the treatment of

palmar hyperhidrosis or axillary bromidrosis. METHODS: Fifty patients with

palmar hyperhidrosis or axillary bromidrosis were injected with 75% phenol into

a total of 98 sides of the T2-T3 or T3-T4 sympathetic trunks and ganglia. The

injected volume was 0.6 to 1.2 ml (average, 0.8 ml) for each side. The technique

of dorsal percutaneous injection was performed under local anesthesia or local

with intravenous general anesthesia and under the guidance of a C-arm

fluoroscope. RESULTS: Forty patients (80%) showed satisfactory results,

including cessation of sweating. The success rates of PTPS were 83.7% (41 of 49

patients) on the left side and 91.8% (45 of 49 patients) on the right side. The

skin temperature of the thumb increased by 5.3 to 5.4 degrees C approximately 1

hour after the phenol injection in patients with satisfactory results, whereas

it increased by only 1.3 to 2.7 degrees C in patients who had unsatisfactory

results. CONCLUSION: PTPS may be a good alternative to endoscopic sympathectomy

to treat palmar hyperhidrosis and axillary bromidrosis. The skin temperature of

the thumb is still a useful index to evaluate preliminarily whether PTPS has

been successful.

 

PMID: 11523673 [PubMed - indexed for MEDLINE]

 

 

 

17: Pediatr Surg Int  2001 Sep;17(7):535-7

 

Endoscopic thoracic sympathetic block by clipping for palmar and axillary

hyperhidrosis in children and adolescents.

 

Lin TS, Huang LC, Wang NP, Chang CC.

 

Department of Surgery, Changhua Christian Hospital, Hung Kuang Institute of

Technology, Chung Shan Medical and Dental College, Taichung, Taiwan, ROC.

 

Endoscopic thoracic sympathectomy or sympathicotomy is a safe and effective

method of treating primary hyperhidrosis (PH), but postoperative compensatory

sweating may be a problem. There are few reports of sympathetic blockade by

clipping for PH. We present our experience of endoscopic thoracic sympathetic

block (ETSB) by clipping in treating palmar (PAH) and axillary hyperhidrosis

(AH) in children and adolescents. Between May 1997 and June 1998, a total of 78

patients with PAH or AH underwent ETSB by clipping using an 8-mm, 0 degrees

thoracoscope. There were 33 males and 45 females with a mean age of 14.1 years

(range 9-16 y). All patients were placed in a semi-sitting position under

single-lumen intubation anesthesia; 52 patients with PAH underwent T2

sympathetic block by clipping at the 2nd and 3rd rib beds, and T3 and T4

sympathetic block was performed at the 3rd, 4th and 5th rib beds in 26 patients

with AH. A total of 156 sympathetic blocks by clipping were achieved. The

operation was usually accomplished within 20 min (range 16-30 min). Most

patients were discharged within 4 h after the operation. There were neither

surgical complications nor mortality. The mean postoperative follow-up period

was 32.7 months (range 26-40). Improvement of PAH or AH could be obtained in all

cases; 70 patients (85.4%) developed compensatory sweating of the trunk and

lower limbs. One patient with PAH underwent a reverse operation with improvement

of the sweating 14 days after removal of the endo-clips. ETSB by clipping is

thus a safe and effective method for treating PH in children and adolescents;

compensatory sweating may be improved after a reverse operation with removal of

the endo-clip.

 

PMID: 11666053 [PubMed - indexed for MEDLINE]

 

 

 

18: Lakartidningen  2001 Aug 22;98(34):3589

 

[Negative sweating]

 

[Article in Swedish]

 

Melander S.

 

Publication Types:

Letter

 

PMID: 11571806 [PubMed - indexed for MEDLINE]

 

 

 

19: Ann Thorac Surg  2001 Aug;72(2):667-8

 

Technical notes on thoracic sympathectomy for essential hyperhidrosis.

 

Kao MC.

 

Publication Types:

Letter

 

PMID: 11515936 [PubMed - indexed for MEDLINE]

 

 

 

20: AORN J  2001 Aug;74(2):178-82, 185-6, 188; quiz 189-91, 193-4

 

Thoracoscopic sympathectomy for palmar hyperhidrosis.

 

Allen GM.

 

New York Presbyterian Hospital, New York, USA.

 

Palmar hyperhidrosis (i.e., excessive sweating of the palms) usually appears at

puberty and causes psychological, social, educational, and occupational problems

for people who suffer from it. Although many treatments have been used, the only

treatment that permanently eradicates the condition is sympathectomy. The advent

of thoracoscopic surgery has allowed surgeons to perform sympathectomy as an

outpatient procedure that is safe and effective and produces life-changing

results for patients.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 11503199 [PubMed - indexed for MEDLINE]

 

 

 

21: Br J Dermatol  2001 Aug;145(2):298-301

 

Ultrastructure of the hyperhidrotic eccrine sweat gland.

 

Bovell DL, Clunes MT, Elder HY, Milsom J, Jenkinson DM.

 

School of Biological and Biomedical Sciences, Glasgow Caledonian University,

Glasgow G4 0BA, UK.

 

BACKGROUND: Hyperhidrosis is the secretion of inappropriately large amounts of

sweat by eccrine glands; it can be very debilitating. Little is known of the

causes of primary hyperhidrosis. OBJECTIVES: To determine whether the glands

exhibit any structural abnormality in primary hyperhidrosis. METHODS: Skin

biopsies were obtained from the axilla (n = 6) or neck (n = 2) of individuals

aged 26-62 years with primary hyperhidrosis and from five age- and sex-matched

normal individuals, with informed consent and ethical committee approval.

Samples were prepared by standard methods for light and electron microscopic

examination. RESULTS: All characteristics observed in the hyperhidrotic

specimens were consistent with the changes seen in normal glands following

strong activation: degranulation of the granular (dark) cells, dilatation of the

basolateral infoldings and the canaliculi of the non-granular (clear) cells,

contraction of the myoepithelial cells and thickening of the basal lamina, and

presence of cellular debris including lipid droplets in the gland lumen.

Pathological changes were not observed. CONCLUSIONS: The present finding of the

absence of structural defects in the glands indicates that future studies should

concentrate on the investigation of neurohumoral or secretory cell metabolic

abnormalities.

 

PMID: 11531796 [PubMed - indexed for MEDLINE]

 

 

 

22: Lakartidningen  2001 Jul 25;98(30-31):3356

 

[Surgery of excessive hand sweating in the past and now]

 

[Article in Swedish]

 

Rabow L.

 

Publication Types:

Historical Article

Letter

 

PMID: 11521345 [PubMed - indexed for MEDLINE]

 

 

 

23: J Neurosurg  2001 Jul;95(1 Suppl):58-63

 

Associated change in plantar temperature and sweating after transthoracic

endoscopic T2-3 sympathectomy for palmar hyperhidrosis.

 

Chen HJ, Liang CL, Lu K.

 

Department of Neurosurgery, Chang Gung University and Medical Center at

Kaohsiung, Taiwan. chenmd@ms8.hinet.net

 

OBJECT: Transthoracic endoscopic T2-3 sympathectomy is currently the treatment

of choice for palmar hyperhidrosis. Compensatory sweating of the face, trunk,

thigh, and sole of the foot was found in more than 50% of patients who underwent

this procedure. The authors conducted this study to investigate the associated

intraoperative changes in plantar skin temperature and postoperative plantar

sweating. METHODS: One hundred patients with palmar hyperhidrosis underwent

bilateral transthoracic endoscopic T2-3 sympathectomy. There were 60 female and

40 male patients who ranged in age from 13 to 40 years (mean age 21.6 years).

Characteristics studied included changes in palmar and plantar skin temperature

measured intraoperatively, as well as pre- and postoperative changes in plantar

sweating and sympathetic skin responses (SSRs). In 59 patients (59%) elevation

of plantar temperature was demonstrated at the end of the surgical procedure. In

this group, plantar sweating was found to be exacerbated in three patients (5%);

plantar sweating was improved in 52 patients (88.1%); and no change was

demonstrated in four patients (6.8%). In the other group of patients in whom no

temperature change occurred, increased plantar sweating was demonstrated in

three patients (7.3%); plantar sweating was improved in 20 patients (48.8%); and

no change was shown in 18 patients (43.9%). The difference between temperature

and sweating change was significant (p = 0.001). Compared with the

presympathectomy rate, the rate of absent SSR also significantly increased after

sympathectomy: from 20 to 76% after electrical stimulation and 36 to 64% after

deep inspiration stimulation, respectively (p < 0.05). CONCLUSIONS: In contrast

to compensatory sweating in other parts of the body after T2-3 sympathetomy,

improvement: in plantar sweating was shown in 72% and worsened symptoms in 6% of

patients. The intraoperative plantar skin temperature change and perioperative

SSR demonstrated a correlation between these changes.

 

PMID: 11453433 [PubMed - indexed for MEDLINE]

 

 

 

24: Kyobu Geka  2001 Jul;54(7):555-9

 

[Endoscopic transthoracic sympathectomy (ETS) with a fine 2-mm thoracoscope in

palmar hyperhidrosis]

 

[Article in Japanese]

 

Naruse H, Moriyasu K, Yokokawa H, Ohkura T, Kamio Y, Suzuki K, Suzuki S, Kitami

A, Tanaka H, Suzuki T.

 

Department of Thoracic Surgery, TMG Totsuka Kyoritsu Hospital, Yokohama, Japan.

 

Endoscopic transthoracic sympathectomy (ETS) is an efficient, safe, minimally

invasive procedure, and requires only a short period of hospitalization. We

performed bilateral ETS using a thoracoscope 2 mm in diameter. We performed 120

ETS for the treatment of palmar hyperhidrosis from August 1997 to April 2000.

The patient was placed in the semi-sitting position under general anesthesia,

one-lung ventilation being used; the operation was performed with 2-mm

two-puncture method. The sympathetic chain could be observed through parietal

pleura riding on the costovertebral junctions. A 2-mm Kirschner wire was

employed as an electrode, and the second and third thoracic sympathetic chains

were electro cauterized. A thoracic drain was not used. The needling sites were

only 2 mm in size and could be fixed without suture. For the patient, a small

scar of this size means virtually no scar. The operative times were from 11 min

to 81 min in bilateral ETS. Immediately and dramatic decrease in the sweat

excretion in the palms was noted in all patients. The 95% patients were highly

satisfied with the results. The commonest side effects were compensatory

sweating. This procedure is recommended as the method of choice for the surgical

treatments of palmar hyperhidrosis.

 

PMID: 11452523 [PubMed - indexed for MEDLINE]

 

 

 

25: Am J Surg  2001 Jun;181(6):540-2

 

Microinvasive video-assisted thoracoscopic sympathicotomy for primary palmar

hyperhidrosis.

 

Kim BY, Oh BS, Park YK, Jang WC, Suh HJ, Im YH.

 

Department of Thoracic and Cardiovascular Surgery, Sangmoo Hospital,

Chipyung-Dong 1240, Suh-Gu, 502-270, Kwang-Ju, South Korea.

bykim@mail.chosun.ac.kr

 

BACKGROUND: Although video-assisted thoracoscopic surgery for palmar

hyperhidrosis is now widely accepted as the approach of choice, the optimal

technique has remained a subject of controversy. We have used 2-mm dual port

video-assisted thoracoscopic sympathicotomy for primary palmar hyperhidrosis.

This study evaluates the short-term results of the technique. METHODS: A

retrospective review was carried out of 45 patients, 20 men and 25 women, with a

mean age of 24.2 years. In the period from April 1998 to August 1999, 90

consecutive video-assisted sympathicotomy for primary palmar hyperhidrosis

either in isolation (n = 56) or in combination with axillary and plantar

hyperhidrosis (n = 34) was performed. The mean follow-up period was 11.3 months.

Attention was focused on patient's satisfaction, complications, and morbidity.

RESULTS: Dry limbs were immediately achieved in all patients after surgery.

There was no operative mortality and one case of transient Horner's syndrome

developed. Eight of 20 with plantar hyperhidrosis showed simultaneous

improvement. The overall mean satisfaction rate was 92% +/- 2% with a median 93%

improvement using a visual linear analogue scale from 0% (poor) to 100%

(excellent). Only 2 patients were dissatisfied with the operative results owing

to compensatory hyperhidrosis, which occurred in 25 patients and improved in 20

patients within the follow-up period. CONCLUSIONS: The video-assisted

thoracoscopic sympathicotomy with 2-mm endoscope is a speedy and safe way of

controlling hyperhidrosis with excellent cosmetic results while minimizing

complications.

 

PMID: 11513781 [PubMed - indexed for MEDLINE]

 

 

 

26: Eur J Cardiothorac Surg  2001 Jun;19(6):951-2

 

Comment on:

 Eur J Cardiothorac Surg. 2000 Jun;17(6):691-6.

 

Thoracoscopic sympathectomy for craniofacial hyperhidrosis.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 11482300 [PubMed - indexed for MEDLINE]

 

 

 

27: Hawaii Med J  2001 May;60(5):126, 137

 

Comment in:

 Hawaii Med J. 2001 May;60(5):122, 129, 135.

 

Improvement in quality of life after bilateral transthoracic endoscopic

sympathectomy for palmar hyperhydrosis.

 

Lau WT, Lee JD, Dang CR, Lee L.

 

OBJECTIVE: To evaluate the efficacy of bilateral transthoracic endoscopic

sympathectomy (TES), in alleviating symptoms and improving quality of life for

patients in Hawaii. DESIGN: Retrospective cohort study. MATERIALS AND METHODS:

Patients who had undergone TES were evaluated by phone interview and the SF-36

questionnaire to assess improvements in symptoms and the development of

compensatory hyperhydrosis. SF-36 scores were divided into 8 scales and

evaluated by one-tailed t-test. RESULTS: Since 1999, eight patients (five women

and three men, mean age 27.4 years old, range 15-41 yrs) underwent TES without

significant complication. Length of hospital stay was less than one day for all

patients except one, who stayed four days. Estimated operative blood lost was

less than 100 ml and no blood transfusions were required. No Horner's syndrome

was suffered. After a mean follow-up of 7.0 months (range 1.2-15.8 months), none

of the patients had recurrent symptoms in the palms but all reported moderate

compensatory hyperhydrosis located mainly in the trunk and lower extremities

(two patients). SF-36 scores showed significant improvements in social

functioning (p < 0.005), mental health (p < 0.049), and role-physical (p <

0.020) along with an increase in bodily pain (p < 0.012). CONCLUSION: Although

TES resulted in some bodily pain and compensatory hyperhydrosis; these elements

were outweighed by the improvement in palmar symptoms, social, mental, and role

physical functioning, and overall quality of life.

 

PMID: 11432050 [PubMed - indexed for MEDLINE]

 

 

 

28: Hawaii Med J  2001 May;60(5):122, 129, 135

 

Comment on:

 Hawaii Med J. 2001 May;60(5):126, 137.

 

Severe palmar hyperhidrosis treated by transthoracic endoscopic sympathectomy.

 

Goldstein N.

 

Publication Types:

Comment

Editorial

 

PMID: 11432048 [PubMed - indexed for MEDLINE]

 

 

 

29: Kyobu Geka  2001 May;54(5):379-83

 

[Endoscopic thoracic sympathectomy for palmar, axillary and plantar

hyperhidrosis: intermediate-term results]

 

[Article in Japanese]

 

Fukushima H, Makimura S, Takae H, Yao Y, Ishimaru S.

 

Department of Surgery II, Tokyo Medical University, Tokyo, Japan.

 

From June 1996 to June 2000, 477 endoscopic thoracic sympathectomies (ETS) were

performed in 242 patients with palmar hyperhidrosis. Among these, 190 patients

were studied who received bilateral sympathectomy (T 2-T 3 ganglionectomy) and

were followed for over six months. There were 114 females and 76 males with a

mean age of 26 years. Palmar hyperhidrosis was found in all patients and

axillary hyperhidrosis in 138 (73%) and plantar hyperhidrosis in 186 (98%)

preoperatively. The degrees of palmar, axillary and plantar perspiration were

checked immediately (1-2 weeks, 190 patients), as well as in the early (1 year,

190 patients) and late (2-4 years, 65 patients) postoperative periods. In all

patients, the hands became dry or normal condition immediately after the

operation, and this continued to late period. Disappearance or decrease of

axillary sweating was found in 128 patients (93%) in the immediate period and

107 patients (78%) in the early period. Disappearance or decrease of plantar

sweating was found in 134 patients (72%) in the immediate period and 115

patients (62%) in the early period. Among 65 patients examined in the late

period, axillary hyperhidrosis was found in 24 (37%), and plantar hyperhidrosis

was found in 52 (80%). Compensatory sweating was found in 80 patients (42%) in

the immediate period and 137 patients (72%) in the early period. In the late

period, compensatory sweating developed in 56 patients (86%). In the immediate

period, 175 patients (92%) were satisfied with the results of the operation, but

this decreased to 83% and 72% at early and late period. However ETS was

remarkably effective for palmar or axillary hyperhidrosis and relatively

effective for plantar hyperhidrosis, but development of compensatory sweating

did occur in some cases.

 

PMID: 11357300 [PubMed - indexed for MEDLINE]

 

 

 

30: Surg Endosc  2001 May;15(5):435-41

 

Thoracoscopic sympathectomy for palmar hyperhidrosis. Ablate or resect?

 

Hashmonai M, Assalia A, Kopelman D.

 

Department of Surgery B, The Rambam Medical Center and the Faculty of Medicine,

Technion Israel Institute of Technology, P.O. Box 9621, Haifa 31096, Israel.

hasmonai@inter.net.il

 

BACKGROUND: Upper thoracoscopic sympathectomy, obtained either by ablation or

resection of the appropriate ganglia, is now the preferred treatment for primary

palmar hyperhidrosis. Therefore, we undertook a review to compare the relative

efficacy of these two techniques. METHODS: A Medline search was performed for

the years 1974-99 to identify all published studies of thoracoscopic

sympathectomy for hyperhidrosis. RESULTS: In all, 33 studies were identified and

divided into two groups-ablation and resection. When the resection method was

used, the immediate success rate was 99.76%, whereas the ablation method

achieved dry hands in 95.2% of cases (p = 0.00001). Palmar sweating recurred in

0% of patients treated via resection and -4.4% treated with ablation. Ptosis was

noted in 0.92% of cases after ablation and in 1.72% after resection (p = 0.017).

CONCLUSIONS: Resection yields superior results, yet the majority of surgeons

ablate, probably because it is easier, requires a shorter operating time, leads

to fewer cases of Horner's syndrome, and because resympathectomy eventually

overcomes initial failure.

 

Publication Types:

Review

Review Literature

 

PMID: 11353955 [PubMed - indexed for MEDLINE]

 

 

 

31: Lakartidningen  2001 Apr 11;98(15):1764-5

 

[Postoperative complications are frequent after surgery for palmar sweating and

facial redness. Effects of the treatment must be considered with regard to the

risk of side-effects]

 

[Article in Swedish]

 

Raf L.

 

Patientskadenamnden och Landstingens Omsesidiga Forsakringsbolag, Stockholm.

lars.raef@swipnet.se

 

PMID: 11374001 [PubMed - indexed for MEDLINE]

 

 

 

32: Lakartidningen  2001 Apr 11;98(15):1766-72

 

[Long-term effects after surgery for hand sweating and facial blushing. Patients

are satisfied in spite of troublesome side-effects]

 

[Article in Swedish]

 

Drott C, Claes G, Rex L, Dalman P, Gothberg G, Fahlen T.

 

Kirurgiska kliniken, Boras lasarett. christer.drott@telia.com

 

The thoracoscopic technique has simplified surgery on the upper thoracic chain.

This comparatively minimally traumatic approach has resulted in a pronounced

increase in the number of procedures. The effect of ETS on severe palmar

hyperhidrosis and facial blushing is very good. These conditions often cause

social, professional and emotional handicaps. Side-effects, especially

compensatory sweating (increased sweating on the trunk and legs), can, however,

be severe. The procedure should be used only when the hyperhidrosis or facial

blushing is severely detrimental to the quality of life. The expected effects,

side-effects and risks for complications must be made clear before patients are

accepted for ETS.

 

PMID: 11374002 [PubMed - indexed for MEDLINE]

 

 

 

33: Ann Thorac Surg  2001 Apr;71(4):1116-9

 

Early complications of thoracic endoscopic sympathectomy: a prospective study of

940 procedures.

 

Gossot D, Kabiri H, Caliandro R, Debrosse D, Girard P, Grunenwald D.

 

Thoracic Department, Institut Mutualiste Montsouris, Paris, France.

dominique.gosso@imm.fr

 

BACKGROUND: Thoracic endoscopic sympathectomy (TES) has become the surgical

technique of choice for treating intractable palmar hyperhidrosis and is usually

considered as a simple and safe procedure. To evaluate the complication rate of

TES, we conducted a prospective study of peri- and postoperative complications.

METHODS: From 1995 to 1999, 467 consecutive patients were operated on for upper

limb hyperhidrosis. There were 164 men and 303 women, ranging in age from 15 to

59 years (mean 31 years). In all but 5 cases, the procedure was bilateral.

Eleven patients underwent a reoperation for failure; thus the total number of

sympathectomies was 940. The procedure was performed in two stages in 182

patients and in one stage in 267 patients. All patients were seen 1 month after

the operation. RESULTS: There was no mortality. The mean postoperative hospital

stay was 2.3 days in the group of patients who were operated on in two stages

and 1.1 day in patients who were operated on in one stage. There were three

major complications: one tear of the right subclavian artery and two

chylothoraces. There were 25 cases (5.3%) of bleeding (300 to 600 mL) during

dissection of the sympathetic trunk due to injury to an intercostal vein; in all

cases it was controlled thoracoscopically. There were 12 pneumothoraces (1.3%)

after removal of chest tubes. All of these were unilateral. Four required chest

drainage for a period of less than 24 hours. One patient had a mild pleural

effusion. Four patients had a unilateral partial Horner Syndrome (0.4%) that

disappeared within 3 months in 2 patients. The other 2 patients were lost to

follow-up. One patient complained of rhinitis. CONCLUSIONS: Although morbidity

was low, significant complications of TES occurred. Patients should be clearly

warned that TES is not as minor a procedure as usually asserted. Complications

as well as adverse effects should be considered when discussing this surgical

indication.

 

PMID: 11308146 [PubMed - indexed for MEDLINE]

 

 

 

34: Eur J Cardiothorac Surg  2001 Apr;19(4):545-6

 

Comment on:

 Eur J Cardiothorac Surg. 2000 Jun;17(6):697-701.

 

Monitoring of palmer skin temperature in thoracoscopic sympathectomy.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 11394357 [PubMed - indexed for MEDLINE]

 

 

 

35: J Laparoendosc Adv Surg Tech A  2001 Apr;11(2):59-62

 

Video-assisted thoracoscopic T2 sympathetic block by clipping for palmar

hyperhidrosis: analysis of 52 cases.

 

Lin TS, Huang LC, Wang NP, Lai CY.

 

Department of Surgery, Changhua Christian Hospital, Changhua City, Taiwan, ROC.

Lin8065cms14.hinet.net

 

BACKGROUND: Endoscopic thoracic sympathectomy or sympathicotomy is a standard

method in treating palmar hyperhidrosis, but postoperative compensatory sweating

may be troublesome in some patients. Therefore, we designed a new technique for

only T2 sympathetic blocking by clipping instead of interruption of the

sympathetic trunk. PATIENTS and METHODS: Between September 2000 and July 2001,

we saw a total of 100 patients with palmar hyperhidrosis who underwent

video-assisted thoracoscopic sympathetic blocking of the T2 ganglion. All

patients were placed in a semisitting position under single-lumen intubated

anesthesia. We performed sympathetic blocking by clipping of the T2 ganglion at

the level of the second and third rib beds using an 8-mm, 0 degree thoracoscope

(Storz). RESULTS: We supposed that the postoperative improvement in palmar

hyperhidrosis would be perfect. The operation could be accomplished within 30

minutes. All patients were discharged within 4 hours after the operation.

Surgical complications were minimal, without surgical mortality. A few patients

were willing to receive the reverse operation and should get improvement of

compensatory sweating after removal of the endo clips. CONCLUSION: We believe

that video-assisted thoracoscopic T2 sympathetic block by clipping will be a

safe and effective method of treating patients with palmar hyperhidrosis.

Compensatory sweating may be improved by the reverse operation: removal of the

endo clip.

 

PMID: 11327127 [PubMed - indexed for MEDLINE]

 

 

 

36: Minerva Chir  2001 Apr;56(2):193-7

 

[Minimally-invasive endoscopic transthoracic sympathectomy of the upper limbs. A

new method]

 

[Article in Italian]

 

Raposio E, Filippi F, Renzi M, Caregnato P, Capello C, Santi PL.

 

Istituto Nazionale per la Ricerca sul Cancro, Cattedra di Chirurgia Plastica,

Universita degli Studi, Genoa, Italy.

 

OBJECTIVE: Indications for endoscopic transthoracic upper dorsal sympathectomy

are axillary and palmar hyperhidrosis, upper extremities ischemia (due to, e.g.,

Raynaud s disease), and upper extremities causalgia. METHODS: At present, this

methodology relies on (at least) double trocar insertion (per side) and/or

carbon dioxide insufflation. Thus, although this approach, compared with the

traditional  open  sympathectomy techniques, it guarantees the smallest number

of postoperative complications, it still determines a certain amount of

postoperative discomfort as well as a risk of complications related to carbon

dioxide insufflation, as intraoperative profound bradycardia and hypotension due

to mediastinal shift, and postoperative subcutaneous emphysema. From December

1995, we are using a minimally-invasive endoscopic transthoracic sympathectomy

technique, performed by a single-entry specifically modified thoracoscope and

without the need for carbon dioxide insufflation, with the aim to reduce the

drawbacks associated with the above-mentioned currently adopted endoscopic

techniques. After general anesthesia with double-lumen endotracheal tube, with

the patient placed in a half-sitting position with both arms abduced to 90

degrees, a 1 cm incision is performed, along the midclavear line (in male

patients) or the anterior axillary line (in female patients), in the second or

third intercostal space. RESULTS: The effects of sympathectomy are immediate,

and the patients wake up with warm and dry hands and axillae. CONCLUSIONS: In

personal opinion, this  single-entry  technique, compared with other reported

approaches, should minimize any damage to the intercostal neurovascular bundle,

while avoiding the complications connected with carbon dioxide insufflation.

 

PMID: 11353353 [PubMed - indexed for MEDLINE]

 

 

 

37: Neurosurg Clin N Am  2001 Apr;12(2):321-7

 

Endoscopic upper thoracic sympathectomy.

 

Vallieres E.

 

Division of Cardiothoracic Surgery, University of Washington Medical Center,

Seattle 98195, USA.

 

Thoracoscopic sympathectomy provides a superb surgical option for the many

patients with incapacitating essential hyperhidrosis. Whether one thoracoscopic

approach to sympathectomy is ever likely to prevail is doubtful, as the results

of the various reported techniques seem to be quite similar. There are definite

advantages to the single-port approaches, which are faster and usually do not

require repositioning of the patient to do both sides. In the rare instances

where dense apical adhesions are encountered or when significant bleeding is

encountered from one of the intercostal vessels, the two- or three-port

approaches definitely provide better control (see commentary in article by Kohno

and Takamoto). Surgeon preference probably dictates which approach is used at

the different centers. Compensatory sweating remains a frequent and sometimes

serious complication of the procedure, particularly in individuals living in hot

climates. An understanding of its mechanisms needs improvement, with the hope of

preventing its occurrence in the future. In the meantime, patients have to be

informed of its frequency, and operations could probably be tailored to the

patients' needs and their local climate.

 

PMID: 11525210 [PubMed - indexed for MEDLINE]

 

 

 

38: Pacing Clin Electrophysiol  2001 Apr;24(4 Pt 1):524-5

 

Bradycardia and permanent pacing after bilateral thoracoscopic T2-sympathectomy

for primary hyperhidrosis.

 

Lai CL, Chen WJ, Liu YB, Lee YT.

 

Department of Emergency Medicine, National Taiwan University, 7 Chung-Shan South

Rd., Taipei 10016 Taiwan.

 

A 23-year-old woman with craniofacial hyperhidrosis underwent bilateral

thoracoscopic T2-sympathectomy. Marked sinus bradycardia with a mean heart rate

of 49 beats/min by Holter ECG monitoring occurred after the procedure and

persisted for > 2 years. Normal sinus node function was found by an invasive

electrophysiological study and unopposed vagotonia after sympathectomy was

diagnosed. A permanent pacemaker was implanted. Although reduced heart rate is a

common phenomenon after bilateral dorsal sympathectomy, intractable bradycardia

with permanent pacing is rare. This patient demonstrates one of the potential

cardiac complications of bilateral sympathectomy.

 

PMID: 11341096 [PubMed - indexed for MEDLINE]

 

 

 

39: Surg Laparosc Endosc Percutan Tech  2001 Apr;11(2):152; discussion 153

 

Thoracoscopic sympathectomy.

 

Ng WT.

 

Publication Types:

Letter

 

PMID: 11330386 [PubMed - indexed for MEDLINE]

 

 

 

40: Surg Laparosc Endosc Percutan Tech  2001 Apr;11(2):152-3

 

Thoracoscopic sympathectomy.

 

Kao MC.

 

Publication Types:

Letter

 

PMID: 11330385 [PubMed - indexed for MEDLINE]

 

 

 

41: Contact Dermatitis  2001 Mar;44(3):200

 

Comment on:

 Contact Dermatitis. 2000 Feb;42(2):119-20.

 

Irritant contact dermatitis of the hands following thoracic sympathectomy.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 11218010 [PubMed - indexed for MEDLINE]

 

 

 

42: Eur J Surg  2001 Mar;167(3):237-8

 

Comment on:

 Eur J Surg. 2000 Jan;166(1):65-9.

 

"Operative monitoring of hand and axillary temperature during endoscopic

superior thoracic sympathectomy for the treatment of palmar hyperhidrosis".

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 11316416 [PubMed - indexed for MEDLINE]

 

 

 

43: J Am Coll Surg  2001 Mar;192(3):418-20

 

Posterior approach for the simultaneous, bilateral thoracoscopic sympathectomy.

 

de Haan J, Mackaay AJ, Cuesta MA, Rauwerda JA.

 

Department of Surgery, Academic Hospital Vrije Universiteit, Amsterdam, The

Netherlands.

 

If there is an indication for sympathectomy in the case of severe hyperhidrosis

or rubeosis, in our opinion the posterior approach is preferable because of the

advantages in surgical technique and anesthesia. Bilateral treatment can be

accomplished in a single admission, with all the concomitant advantages.

 

PMID: 11245387 [PubMed - indexed for MEDLINE]

 

 

 

44: Neurosurgery  2001 Mar;48(3):702

 

Comment on:

 Neurosurgery. 1992 Jan;30(1):131-5.

 Neurosurgery. 1993 Feb;32(2):327-9.

 Neurosurgery. 1994 Feb;34(2):262-8; discussion 268.

 Neurosurgery. 2000 May;46(5):1254-7; discussion 1257-8.

 

Microinvasive transaxillary thoracoscopic sympathectomy: technical note.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 11270568 [PubMed - indexed for MEDLINE]

 

 

 

45: Dtsch Med Wochenschr  2001 Feb 23;126(8):224

 

[Indications and results of video thoracoscopic sympathectomy]

 

[Article in German]

 

Wohlrab J, Marsch WC.

 

Publication Types:

Letter

 

PMID: 11256032 [PubMed - indexed for MEDLINE]

 

 

 

46: Surg Endosc  2001 Feb;15(2):126-8

 

Endoscopic clipping in video-assisted thoracoscopic sympathetic blockade for

axillary hyperhidrosis. An analysis of 26 cases.

 

Lin TS.

 

Department of Surgery, Changhua Christian Hospital, Chung Shan Medical and

Dental College, 135 Nan-Siao Street, Changhua City, Taiwan, Republic of China.

 

BACKGROUND: Endoscopic thoracic sympathectomy or sympathicotomy is the standard

method for the treatment of axillary hyperhidrosis. But postoperative

compensatory sweating may be troublesome in some patients. Therefore, we use

endoclips to perform the T3 and T4 sympathetic blockade instead of permanently

interrupting the transmission of nerve impulses from the sympathetic trunk.

METHODS: Between May 1997 and June 1998, a total of 26 patients with axillary

hyperhidrosis underwent video-assisted thoracoscopic sympathetic blocking of the

T3 and T4 ganglia at our hospital. There were 10 men and 16 women with a mean

age of 31.7 years (range, 16-47). All patients were placed in a semi-sitting

position under single-lumen intubated anesthesia. We performed the sympathetic

blockade by clipping the T3 and T4 ganglia at the level of the third, fourth,

and fifth rib beds using an 8-mm 0 degree thoracoscope. RESULTS: Bilateral T3

and T4 sympathetic blockade was achieved in all 26 patients. The operation was

usually completed within 30 min (range, 20-42). Most patients were discharged

within 4 h after the operation. Surgical complications were minimal, with only

one case of segmental atelectasis (3.8%). There were no deaths. The mean

postoperative follow-up period was 31.3 months (range, 24-37). Twenty-three

patients (88.5%) developed compensatory sweating of the trunk and lower limbs.

Twenty-four patients (92.3%) were satisfied with the results of the operation.

Improvement of axillary hyperhidrosis was obtained in all patients. One patient

underwent a reverse operation to remove the endoclips due to intolerable

compensatory sweating; improvement was seen 25 days after removal of the clips.

CONCLUSION: Video-assisted thoracoscopic T3 and T4 sympathetic blockade by

clipping is a safe and effective method for the treatment of patients with

axillary hyperhidrosis. Patients who experience excessive compensatory sweating

may require a reverse operation for endoclip removal.

 

Publication Types:

Evaluation Studies

 

PMID: 11285952 [PubMed - indexed for MEDLINE]

 

 

 

47: Surg Endosc  2001 Feb;15(2):222

 

Transthoracic endoscopic sympathectomy.

 

Kao MC.

 

Publication Types:

Letter

 

PMID: 11285974 [PubMed - indexed for MEDLINE]

 

 

 

48: Neurology  2001 Jan 23;56(2):254-6

 

Basal forebrain malformation with hyperhidrosis and hypothermia: variant of

Shapiro's syndrome.

 

Klein CJ, Silber MH, Halliwill JR, Schreiner SA, Suarez GA, Low PA.

 

Department of Neurology, Mayo Clinic, Rochester, MN, USA.

 

A 62-year-old woman presented with episodic sweating and shivering with reduced

core temperature. Brain MRI demonstrated a basal forebrain malformation.

Physiologic testing included EEG, SPECT, heat challenge, and autonomic testing.

Glycopyrrolate aborted spells and raised core temperature. Hypothalamic

dysregulation is likely the primary pathophysiology in the setting of other

forebrain anomalies. These findings expand the structural abnormalities and

treatment options within the temperature dysregulating conditions of Shapiro's

syndrome and "diencephalic epilepsy."

 

PMID: 11160966 [PubMed - indexed for MEDLINE]

 

 

 

49: Acta Anaesthesiol Scand  2001 Jan;45(1):123-6

 

Bilateral pulmonary edema after endoscopic sympathectomy in a patient with

glucose-6-phosphate dehydrogenase deficiency.

 

Lan CJ, Luk HN, Wu CT, Chang WK, Tsou MY, Lui PW, Lee TY.

 

Department of Anesthesiology, Veterans General Hospital-Taipei, School of

Medicine, National Yang-Ming University, Taiwan, ROC. blues729@ms36.hinet.net

 

Transaxillary endoscopic sympathectomy of thoracic ganglia (T2-T3) has recently

gained wider acceptance as the treatment of choice for palmar hyperhidrosis. It

requires one-lung ventilation to facilitate the surgery. One-lung ventilation,

however, is not without complications, among which acute pulmonary edema has

been reported. In this case report, we present a patient with palmar

hyperhidrosis complicated by glucose-6-phosphate dehydrogenase (G-6-PD)

deficiency, who received bilateral endoscopic sympathectomy under alternate

one-lung anesthesia, and developed acute pulmonary edema immediately after

recruitment of the successive collapsed lung. The effects of hypoxemia, G-6-PD

deficiency and sympathectomy might all add to the development of acute pulmonary

edema secondary to reexpansion of each individual lung after alternate one-lung

ventilation. The possibilities of the inferred causes are herein discussed.

 

PMID: 11152024 [PubMed - indexed for MEDLINE]

 

 

 

50: Ann Chir Gynaecol  2001;90(3):195-9

 

Efficacy and safety of thoracoscopic sympathicotomy for hyperhidrosis of the

upper limb. Results of 734 sympathicotomies.

 

Neumayer CH, Bischof G, Fugger R, Imhof M, Jakesz R, Plas EG, Herbst FR, Zacherl

J.

 

Universitatsklinik fur Chirurgie, Allgemeines Krankenhaus der Stadt Wien,

Universitat Wien, Vienna, Austria.

 

BACKGROUND: Thoracoscopic sympathicotomy (TS) evolved as treatment of choice in

severe hyperhidrosis. The aim of this study was to assess the role of

video-assistance in TS (VATS) versus conventional TS (CTS) for primary

hyperhidrosis of the upper limb with regard to safety, side-effects and

long-term outcome. METHODS: 734 TS were performed from below T1 to T4 in 406

patients. In the CTS and in the VATS group 558 and 176 procedures were

performed, respectively. Follow-up was completed in 82% of all patients after a

median observation period of 16 years. RESULTS: Dry limbs were immediately

achieved in 92% (CTS) and 97% (VATS, p = 0.98). Only one patient (CTS) underwent

conversion due to bleeding. In the CTS group Horner's syndrome occurred in 2.2%

and rhinitis in 9.9% of procedures. No patient of the VATS group experienced

Horner's syndrome (p = 0.025), 3 patients developed rhinitis (p = 0.11). At

follow-up compensatory sweating was observed in 67.6% vs. 55.6% (p = 0.051) and

gustatory sweating in 50.4% and 33.3% (p = 0.01). There were 5 failures or

recurrences (1.9%) in the CTS group and 2 (2.8; p > 0.05) in the VATS group at

reevaluation. Overall 6.5% (CTS) and 5.6% (VATS) of patients regret the

operation (p = 0.7). CONCLUSIONS: We observed a significant decrease of the

incidence of complete or incomplete Horner's syndrome and gustatory sweating

when the procedure was guided by video-imaging while success rate was similar

when compared with CTS.

 

PMID: 11695794 [PubMed - in process]

 

 

 

51: Ann Chir Gynaecol  2001;90(3):189-92

 

Efficacy of endoscopic thoracic sympathicotomy along with severing the Kuntz

nerve in the treatment of chronic non-infectious rhinitis.

 

Duarte JB, Kux P.

 

Department of Surgery, Mater Dei Hospital and Belvedere Clinic, Fundacao

Cardiovascular Sao Francisco de Assis, Belo Horizonte, Brazil.

duartejb@horiz.com.br

 

BACKGROUND: The ethiopathogenic diagnosis of rhinitis is laborious and the

clinical treatment is unsatisfactory in many cases. After endoscopic thoracic

sympathicotomy (ETS), some patients related improvement of the symptoms of

chronic non-infectious rhinitis (CNIR). AIM: To study the influence of ETS

associated with the severing of the Kuntz nerve in the follow-up of patients

suffering from CNIR. MATERIAL AND METHOD: From October, 1993 to February, 2001,

117 patients (post-op. follow-up from 2 to 88 months; 46 males and 71 females;

median age 24.9 years) were submitted to bilateral ETS and severing of the Kuntz

nerve for treatment of hyperhidrosis and chronic non-festering rhinitis. The

sympathetic trunk was severed at different levels according to hyperhidrosis

location and rhinitis. RESULT: Rhinitis was cured in 52 patients (44.4%), was

improved in 43 patients (36.8%), and in 22 patients (18.8%) there was no change.

In 3 patients specifically operated on for treatment of CNIR, symptoms

disappeared. CONCLUSION: The results of the present investigation confirmed the

benefits of ETS associated with severing of the Kuntz nerve in the treatment of

CNIR. We recommend this procedure for the treatment of rhinitis associated with

hyperhidrosis and also for the treatment of specific, isolated cases of CNIR.

 

PMID: 11695792 [PubMed - in process]

 

 

 

52: Ann Chir Gynaecol  2001;90(3):206-8

 

Right vs left side thoracoscopic sympathectomy: effects of CO2 insufflation on

haemodynamics.

 

El-Dawlatly AA, Al-Dohayan A, Samarkandi A, Algahdam F, Atef A.

 

Department of Anaesthesia, College of Medicine, King Saud University, Riyadh,

Saudia Arabia. dawlatly@ksu.edu.sa

 

BACKGROUND AND AIMS: Currently, few reports of the haemodynamic impact of

intrapleural CO2 insufflation in the clinical setting are available. Therefore,

we conducted the present study to compare the haemodynamic changes between right

and left side thoracoscopic sympathectomy (TS) for treatment of palmar

hyperhidrosis (PH) under general anaesthesia. MATERIALS AND METHODS: 20 adult

patients (17 males) undergoing TS were randomly allocated to two groups (each

10); group A, right side and group B, left side TS procedures were performed

under general anaesthesia with single-lumen endotracheal tube. Besides the

routine monitoring of vital signs, non-invasive cardiac output monitor (NICO)

was used to record the stroke volume (SV), cardiac output (CO) and cardiac index

(CI). Intrapleural CO2 insufflation was used. Anaesthesia was maintained with 1

MAC sevoflurane in 50% nitrous oxide in oxygen with incremental doses of

sufentanil and atracurium when required. Haemodynamic parameters were obtained

every 3 min then averaged over the time of surgery at phases; I) after tracheal

intubation, II) after CO2 insufflation and III) after CO2 deflation. RESULTS:

The CO, CI and SV showed decreased trend in both groups during phase II compared

to phase I with significant differences (P < 0.05). Comparing the CO and CI

variables revealed lower values in group A compared to group B but with

non-significant differences (P > 0.05). While the SV variable showed significant

low value in group A compared to group B (P < 0.05). CONCLUSIONS: Compared to

left side TS, direct compression by CO2 against the venae cava and right atrium

and ventricle during right side TS caused reduction of the venous return and

hence low CO, CI and SV.

 

PMID: 11695797 [PubMed - in process]

 

 

 

53: Ann Chir Gynaecol  2001;90(3):170-1

 

Kuntz's fiber: the scapegoat of surgical failure in sympathetic surgery.

 

Lin CC, Wu HH.

 

Department of Surgery, Tainan Municipal Hospital, Taiwan.

scipio54@ms46.hinet.net

 

Resection of Kuntz's fiber is considered a guarantee to treat Hyperhidrosis in

sympathetic surgery. The incidence of Kuntz's fiber is about 60.0% in clinical

studies while the surgical failure rate is about 1.5% when Kuntz's fiber is

preserved on Endoscopic Thoracic Sympathetic Block by clamping, which is

performed by clamping the upper and lower end of ganglion. We found that

supererogatory resection of Kuntz's fiber is inessential; clamping of upper and

lower ends of the ganglia should be a complete procedure in sympathetic surgery.

Kuntz's fiber plays only anatomic, and no clinical role in surgical failure of

sympathetic surgery.

 

PMID: 11695786 [PubMed - in process]

 

 

 

54: Ann Chir Gynaecol  2001;90(3):209-11

 

A survey on anesthesia for thoracoscopic sympathetic surgery in treatment of

hyperhidrosis palmaris in Taiwan.

 

Lee LS, Lin CC, Chung HC, Au CF, Fang HT.

 

Department of Anesthesia and Surgery, Tainan Municipal Hospital, Tainan City,

Taiwan. sam10087@hotmail.com

 

Thoracoscopic approach to sympathetic surgery has gained its popularity and

emerged as the main stream in the treatment of hyperhidrosis palmaris in Taiwan.

Different kinds of anesthesia have been practiced and reported in these

surgeries. We made a survey of anesthetic methods in twelve medical centers and

regional hospitals of the island. It was found out that the choice of the

anesthesia was mainly dependent on the mutual trust and the full communication

between the anesthesiologist and the surgeon, both based on their skills and the

operative methods chosen by the surgeon. Single-lumen endotracheal tube with

general inhalation anesthesia is practiced in most of the hospitals surveyed.

Sevoflurane and desflurane are the choices of the inhalational anesthetic

agents. In short, the anesthesiologists tend to practice the type of anesthesia

that is simple but safe enough to secure the airway of the patient throughout

the thoracoscopic sympathetic surgery.

 

PMID: 11695798 [PubMed - in process]

 

 

 

55: Ann Chir Gynaecol  2001;90(3):172-4

 

Video-assisted thoracoscopic sympathetic ramicotomy for hyperhidrosis--a way to

reduce the complications.

 

Cheng YJ, Wu HH, Kao EL.

 

Department of Surgery, Kaohsiung Medical University Hospital, Taiwan, Republic

of China. yujen.cheng@msa.hinet.net

 

Endoscopic resectional surgery of sympathetic nerves is now the most acceptable

method to treat palmar hyperhidrosis, though the resection of the sympathetic

trunk and ganglia can result in the irreversible compensatory hyperhidrosis. The

ideal way to treat the palmar hyperhidrosis, without the undesirable

complication of the compensatory hyperhidrosis, is still pending. We adapt

endoscopic cutting of the second and third sympathetic rami without injury to

the sympathetic ganglia and trunk, and find that it is a good way to reduce the

complications. Most importantly, it has a cure rate comparable with the

conventional technique. The longer operation time and the higher operation risk

are the drawbacks.

 

PMID: 11695787 [PubMed - in process]

 

 

 

56: Ann Chir Gynaecol  2001;90(3):203-5

 

Upper dorsal thoracoscopic sympathectomy for palmar hyperhidrosis. The use of

harmonic scalpel versus diathermy.

 

Kopelman D, Bahous H, Assalia A, Hashmonai M.

 

Faculty of Medicine, Technion--Israel Institute of Technology, Haifa.

 

BACKGROUND: Upper dorsal thoracoscopic sympathectomy, the treatment of choice

for primary palmar hyperhidrosis, is not devoid of long-term complications, like

Horner's syndrome and postoperative neuralgia. It has been postulated that

propagation of heat induced by diathermy may be responsible for some of these

sequelae. To assess this hypothesis, a study was undertaken to evaluate the use

of harmonic scalpel, which does not dissipate heat. METHOD: Sixteen patients

with primary palmar hyperhidrosis underwent upper dorsal thoracoscopic

sympathectomy using the harmonic scalpel on one side and diathermy on the other.

Follow-up was made two years postoperatively. RESULTS: The length of the

procedure with each instrument was similar. There was no localization of

postoperative pain, which could be attributed to either device. No Horner's

syndrome or postoperative neuralgia occurred. CONCLUSION: The present study

proved the safe use of harmonic scalpel for upper dorsal thoracoscopic

sympathectomy, but did not detect any important advantage of either instrument

over diathermy.

 

PMID: 11695796 [PubMed - in process]

 

 

 

57: Ann Chir Gynaecol  2001;90(3):167-9

 

Endoscopic t4-sympathetic block by clamping (ESB4) in treatment of hyperhidrosis

palmaris et axillaris--experiences of 165 cases.

 

Lin CC, Wu HH.

 

Department of Surgery, Sinlau Christian Hospital, Tainan, Taiwan.

scipio54@ms46.hinet.net

 

Prevention of postoperative complications becomes relatively important when

surgical procedures are easy to learn and perform. Endoscopic Thoracic

Sympathetic Surgery (ETS), which is now more accessible to surgeons after the

2nd International Symposium of Thoracic Sympathicotomy, would be the typical

examples in surgery. Reflex sweating is one of the famous and annoying

complications that surgeons endeavor to avoid but in vain in ETS. Incidentally,

we found that preservation of sympathetic tone to the head is the main

influential factor in avoiding reflex sweating in ETS; and with the lower

sympathetic ganglion blocked, the more sympathetic tone to the head is

preserved. T4-sympathetic block is an ideal procedure that can treat palmar

and/or axillary hyperhidrosis and preserve most of sympathetic tone to head. We

used T4-sympathetic block by clamping (ESB4) in treatment of 165 cases of

Hyperhidrosis et axillaris and attained excellent operative results without

reflex sweating from August 1, 2000 to February 28, 2001. We concluded, ESB4 is

the method that can treat hand and axillary hyperhidrosis without inducing

reflex sweating.

 

PMID: 11695785 [PubMed - in process]

 

 

 

58: Auton Neurosci  2000 Dec 28;86(1-2):99-106

 

Patterns of palmar skin temperature alterations during transthoracic endoscopic

T2 sympathectomy for palmar hyperhidrosis.

 

Lu K, Liang CL, Cho CL, Cheng CH, Yen HL, Rau CS, Tsai YD, Chen HJ, Lee TC.

 

Department of Neurosurgery, Chang Gung Memorial Hospital, 123 Ta-Pei Road,

Niao-Sung Hsiang, Kaohsiung Hsien 833, Taiwan, ROC.

 

Transthoracic endoscopic T2 sympathectomy has been widely applied to the

treatment of a variety of sympathetically mediated disorders. Palmar

hyperhidrosis is probably the most common indication for thoracic sympathectomy,

especially in certain subtropical areas. Which sympathetic ganglion is to be

ablated and how extensive such ablation is enough to eliminate palm sweating are

two important issues. Intraoperative monitoring of palmar skin temperature (PST)

is the most frequently used method for assessing the accuracy as well as

adequacy of ablation of the target sympathetic ganglia. With continuous

monitoring of bilateral PST during the operative course of T2 sympathectomy, it

was possible to depict the alterations of bilateral PST in response to specific

surgical procedures in a real-time manner. For each case, a PST graph was

obtained, which represented the graphical expression of intraoperatively

recorded bilateral PST data plotted against time. The PST graphs of 93

consecutive cases were analysed. Three types of PST graphs existed, reflecting

different responses of bilateral PST to different surgical procedures during the

operation. In Type I PST graph pattern, found in 58 cases, skin incision and

intercostal muscle dissection caused dramatic bilateral PST drop; and unilateral

T2 sympathectomy induced synchronous bilateral PST elevation. Twenty-four cases

demonstrated Type II PST graph pattern, in which unilateral T2 sympathectomy

caused only ipsilateral PST elevation, although the PST-depressing effect of

skin incision and muscle dissection was as significant as in Type I graph

pattern. In the 11 cases who showed Type III PST graph pattern, neither skin

incision nor T2 sympathectomy induced any apparent changes of PST on either

side, giving rise to two rather flat PST curves on the PST graphs. These

findings implicate that reciprocal interactions between bilateral sympathetic

activities exist in the majority of cases, and that crossover sympathetic

modulation may play a role in the neural control of the sudomotor and vasomotor

activities of the palms. This study also provides information regarding how PST

would possibly change following specific surgical procedures during

transthoracic endoscopic T2 sympathectomy, which may be of importance to those

who use intraoperative PST monitoring as a guide in determining whether or not

the correct sympathetic ganglia are ablated for adequate sympathetic denervation

of the palms.

 

Publication Types:

Clinical Trial

 

PMID: 11269931 [PubMed - indexed for MEDLINE]

 

 

 

59: Ann Dermatol Venereol  2000 Dec;127(12):1053-4

 

[Hyperhidrosis: role of surgical treatment]

 

[Article in French]

 

Dumont P.

 

Publication Types:

Editorial

 

PMID: 11173677 [PubMed - indexed for MEDLINE]

 

 

 

60: Ann Dermatol Venereol  2000 Dec;127(12):1065-7

 

[Endoscopic thoracic sympathectomy for isolated axillary hyperhidrosis]

 

[Article in French]

 

Gossot D, Debrosse D, Grunenwald D.

 

Departement de Chirurgie Thoracique, Institut Mutualiste Montsouris, 42,

boulevard Jourdan, 75014 Paris. dominique-gossot@imm.fr

 

BACKGROUND: Endoscopic thoracic sympathectomy is accepted as the treatment of

choice for palmar hyperhidrosis. But the interest and the results of endoscopic

thoracic sympathectomy for isolated axillary hyperhidrosis are still discussed.

PATIENTS AND METHODS: In a series of 435 patients operated on for hyperhidrosis

of the upper limbs during the 5 past years, 23 were suffering from isolated

axillary hyperhidrosis (5.2 p. 100). All patients had been previously treated by

local agents and 3 had iontophoresis. All patients underwent a bilateral

endoscopic thoracic sympathectomy that was performed in one stage. Sympathectomy

was done according to the usual technique but was extended down to T5. All

patients were then contacted by phone to answer a detailed questionnaire. Four

patients were lost for follow-up. The mean follow-up of the 19 remaining

patients was 26 months (ranging 3 to 41 months). RESULTS: There was no

intraoperative or postoperative complication. All patients were discharged the

day after surgery. All but one (95 p. 100) were cured from their axillary

hyperhidrosis. All of them experienced compensatory sweating (100 p. 100). This

compensatory sweating was considered as mild by 8 patients, as embarrassing in 8

and as distressing in 3. Eleven patients complained of excessive dryness of the

hands. This was considered as a minor adverse effect by 8 patients and as

problematic by 3 patients. Finally, 16 patients were satisfied while 3 claimed

they regretted having been operated on. CONCLUSION: The rate of compensatory

sweating and the rate of dissatisfaction are higher after endoscopic thoracic

sympathectomy for axillary hyperhidrosis than after endoscopic thoracic

sympathectomy for palmar hyperhidrosis. Endoscopic thoracic sympathectomy for

axillary hyperhidrosis should be foreseen only when all other therapies have

been attempted.

 

PMID: 11173680 [PubMed - indexed for MEDLINE]

 

 

 

61: Ann Dermatol Venereol  2000 Dec;127(12):1057-63

 

[Endoscopic sympathectomy for palmar and plantar hyperhidrosis: results in 107

patients]

 

[Article in French]

 

Nicolas C, Grosdidier G, Granel F, Barbaud A, Schmutz JL.

 

Service de Dermatologie, Hopital Fournier, 36, quai de la bataille, 54035 Nancy

Cedex.

 

INTRODUCTION: Transthoracic endoscopic sympathectomy for palmar hyperhidrosis is

a safe and effective method. However, no radical and definite treatment exists

for plantar hyperhidrosis. We report our experience, immediate post-operative

and mid-term results after transthoracic and lumbar endoscopic sympathectomy for

palmar and plantar hyperhidrosis. PATIENTS AND METHODS: One hundred and seven of

117 patients cured between January 94 and December 98, answered a questionnaire

regarding their past history, the early post-operative results, side effects and

complications caused by the operation and mid-term results with particular

emphasis on patient satisfaction. RESULTS: Seventy-eight thoracic and lumbar

endoscopic sympathectomies and 125 thoracic endoscopic sympathectomies were

performed. The patients were 30 men (median age 30 years) and 77 women (median

age 26 years). Only women underwent lumbar endoscopic sympathectomy because of

risk of retrograde ejaculation. No severe complications were noted. The success

rate was 96 p. 100 for palmar hyperhidrosis and 98,5 p. 100 for plantar

hyperhidrosis. No recurrences were noted in 97 p. 100 of the patients with

median follow-up of 28 months. The main side effect was compensatory sweating

which was the reason for dissatisfaction for 5 p. 100 of the patients. Cutaneous

dryness and gustatory sweating were also described. However, 95 p. 100 of the

patients were "satisfied" or "very satisfied". CONCLUSION: Our experience proved

that lumbar endoscopic sympathectomy is as safe and effective for treatment of

plantar hyperhidrosis, as thoracic endoscopic sympathectomy for palmar

hyperhidrosis.

 

PMID: 11173679 [PubMed - indexed for MEDLINE]

 

 

 

62: Aust N Z J Surg  2000 Nov;70(11):800

 

Thoracoscopic sympathectomy: a one-port technique.

 

Weight CS, Raitt D, Barrie WW.

 

Department of Surgery, Leicester General Hospital, Leicestershire, UK.

scweight@rcsed.ac.uk

 

BACKGROUND: The present paper describes the development of a one-port technique

for thoracoscopic sympathectomy. METHODS: A 7-mm thorascope with a working

channel for diathermy was used. CONCLUSION: A highly cosmetic, simple, safe,

day-case procedure is achievable.

 

PMID: 11147441 [PubMed - indexed for MEDLINE]

 

 

 

63: Rinsho Shinkeigaku  2000 Nov;40(11):1069-75

 

[Changes of autonomic functions by endoscopic upper thoracic sympathectomy on

idiopathic hyperhidrosis]

 

[Article in Japanese]

 

Kondo M, Mezaki T, Higuchi K, Watanabe Y, Kuzuhara S.

 

Department of Neurology, Matsusaka Central General Hospital, Matsusaka.

 

Changes of autonomic functions before and after bilateral endoscopic upper

thoracic sympathectomy (EUTS) were evaluated in 13 patients with idiopathic

hyperhidrosis, with the sympathetic skin response, coefficient of variation of

R-R intervals, mean heart rate, thermography, and non-invasive Valsalva test of

the tonometry method. EUTS electronically destructs the upper thoracic

sympathetic ganglions which innervate the upper extremities, and partially the

heart. The decrement of mean heart rate, and persistent inhibition of the

vascular contraction and hidrosis of the hands appeared after EUTS. These

manifestations were effect produced by the abortion of sympathetic activity by

EUTS. In 10 of the 12 cases, the baroreceptor sensitivity index II of Valsalva

test which reflects the sympathetic autonomic nervous function of the heart

showed normal pattern after EUTS. Four cases revealed reincrement of both the

blood pressure and heart rate at the latter half phase of the second stage of

the Valsalva test. The sympathetic dysfunction of the heart was limited to the

decrement of mean heart rate although EUTS partially destroys sympathetic fibers

innervating the heart. A long-term study is necessary to evaluate the effect of

EUTS on the cardiac function.

 

PMID: 11332185 [PubMed - indexed for MEDLINE]

 

 

 

64: Clin Neurophysiol  2000 Oct;111(10):1767-70

 

Excitability recovery curve of the sympathetic skin response in healthy

volunteers and patients with palmar hyperhidrosis.

 

Manca D, Valls-Sole J, Callejas MA.

 

Unitat d'EMG, Servei de Neurologia, Departamento de Medicina, IDIBAPS, Hospital

Clinic, Facultad de Medicina, Universitat de Barcelona, Villaroel, 170, 08036,

Barcelona, Spain.

 

OBJECTIVES: Patients with primary palmar hyperhidrosis (PPH) might exhibit

hyperexcitability of the reflex circuits involved in sweating. We hypothesized

that this hyperexcitability could become evident in the study of the

excitability recovery curve of the sympathetic sudomotor skin response (SSR).

METHODS: In 10 patients with PPH and 10 healthy volunteers used as control

subjects, we recorded the SSR in the palm of the right hand to pairs of median

nerve electrical shocks separated by inter-stimuli intervals (ISIs) ranging from

0.5 to 3.5 s. The amplitude of the SSR generated by the second stimulus (SSR2)

was expressed as a percentage of that generated by the first (SSR1), and

compared between control subjects and patients for each ISI. RESULTS: None of

the control subjects showed a recovery of the SSR for ISIs of 1.5 s or less. On

the contrary, patients showed a statistically significant enhancement of the SSR

excitability recovery curve, with onset of recovery at 1.5 s in 5 patients. Two

patients showed a double peak response to single electrical stimulation and were

not considered in the calculation of the SSR recovery curve. Mean excitability

recovery percentages were larger in patients than in control subjects at ISIs of

2, 2.5 and 3 s. CONCLUSIONS: The enhancement of the SSR recovery curve in

patients with PPH suggests hyperexcitability of the somatosympathetic

polisynaptic pathway involved in sweating. This could partly underlie the

pathophysiology of PPH.

 

PMID: 11018490 [PubMed - indexed for MEDLINE]

 

 

 

65: J Laparoendosc Adv Surg Tech A  2000 Oct;10(5):243-7

 

Transthoracic endoscopic sympathectomy for craniofacial hyperhidrosis: analysis

of 46 cases.

 

Lin TS, Fang HY.

 

General Thoracic Surgery, Changhua Christian Hospital, Changhua City, Taiwan,

ROC. Lin8065@ms14.hinet.net

 

BACKGROUND AND PURPOSE: Craniofacial hyperhidrosis may result in social phobia

and has a strong negative impact on the quality of life. The traditional

therapeutic options are psychotherapy and pharmacologic treatment, but these

often fail. We wished to investigate whether transthoracic endoscopic

sympathectomy (TES) of the lower part of the stellate ganglion is efficient and

safe in the treatment of craniofacial hyperhidrosis. PATIENTS AND METHODS:

Between July 1995 and September 1999, a total of 21 men and 25 women with a mean

age of 41.2 years (range 22-58 years) underwent TES for craniofacial

hyperhidrosis. All patients were placed in a semisitting position under

single-lumen intubated anesthesia. We ablated the lower part of the stellate

ganglion at the second rib using a storz 8-mm 0 degrees thoracoscope via one

0.8-cm incision just below each axilla. Questionnaires were sent to all patients

postoperatively. RESULTS: Among these 46 patients, 92 sympathectomies were

performed. Usually, TES was accomplished within 15 minutes (range 7-20 minutes).

The surgical complications were minimal: one segmental atelectasis of the lung

(2%). There was no surgical mortality. With a mean postoperative follow-up of

32.1 months (range 3-51 months), the results of TES were highly satisfactory in

most patients although 37 (80%) developed compensatory sweating of the trunk and

lower limbs, the distribution being the axillae in 15 (33%), back in 36 (78%),

lower chest and abdomen in 22 (48%), lower limbs in 34 (74%) and sole in 1. The

recurrence rates of craniofacial hyperhidrosis were 0 in the first and the

second years and 2% each in the third and fourth years. CONCLUSION:

Transthoracic endoscopic sympathectomy is a safe and effective method for

treating craniofacial hyperhidrosis.

 

Publication Types:

Clinical Trial

 

PMID: 11071402 [PubMed - indexed for MEDLINE]

 

 

 

66: J Neurosurg  2000 Oct;93(2 Suppl):342-3

 

Comment on:

 J Neurosurg. 2000 Jan;92(1 Suppl):44-9.

 

Endoscopic sympathectomy.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 11012078 [PubMed - indexed for MEDLINE]

 

 

 

67: Surg Laparosc Endosc Percutan Tech  2000 Oct;10(5):338-9

 

Comment on:

 Surg Laparosc Endosc Percutan Tech. 2000 Feb;10(1):5-10.

 

Endoscopic thoracic sympathectomy (ETS) is a simple, safe, and effective method

for treating palmar hyperhidrosis.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 11083223 [PubMed - indexed for MEDLINE]

 

 

 

68: Surg Laparosc Endosc Percutan Tech  2000 Oct;10(5):314-8

 

Thoracoscopic sympathectomy.

 

Krasna MJ, Jiao X, Sonett J, Gamliel Z, King K.

 

University of Maryland School of Medicine, Baltimore, USA.

 

The objective was to evaluate the safety and effectiveness of endoscopic

thoracic sympathectomy (ETS) for treatment of a variety of sympathetic

disorders, including hyperhidrosis, splanchnic pain, reflex sympathetic

dystrophy, and Raynaud upper extremity ischemia. Sixty-three ETS procedures were

performed in 34 patients at the University of Maryland Medical System between

March 1992 and August 1999 (14 male patients, 20 female patients; mean age 22

years). The indications for surgery were hyperhidrosis in 26 patients, upper

extremity ischemia in 3 patients, splanchnic pain and reflex sympathetic

dystrophy in 2 patients each, and facial blushing in 1 patient. Preoperative

symptoms resolved completely or improved significantly in 97.1% (33/34) of

patients. One patient with left reflex sympathetic dystrophy had symptoms that

recurred shortly after surgery. There were no major complications; one patient

with hyperhidrosis reported significant compensatory hyperhidrosis. These

findings suggest that ETS is a safe and effective procedure for treatment of a

variety of sympathetic disorders. Its application for hyperhidrosis is very

effective, and its treatment of splanchnic pain, reflex sympathetic dystrophy,

and Raynaud syndrome are rewarding. With increasing experience, ETS should

become established in the repertoire of the thoracic surgeon.

 

Publication Types:

Evaluation Studies

 

PMID: 11083216 [PubMed - indexed for MEDLINE]

 

 

 

69: BMJ  2000 Sep 16;321(7262):703

 

Comment on:

 BMJ. 2000 May 6;320(7244):1221-2.

 

Treating hyperhidrosis. Anticholinergic drugs were not mentioned.

 

Klaber M, Catterall M.

 

Publication Types:

Comment

Letter

 

PMID: 11202933 [PubMed - indexed for MEDLINE]

 

 

 

70: BMJ  2000 Sep 16;321(7262):703

 

Comment on:

 BMJ. 2000 May 6;320(7244):1221-2.

 

Treating hyperhidrosis. Treatment options must be balanced against each other.

 

de Berker D.

 

Publication Types:

Comment

Letter

 

PMID: 11202934 [PubMed - indexed for MEDLINE]

 

 

 

71: BMJ  2000 Sep 16;321(7262):702-3

 

Comment on:

 BMJ. 2000 May 6;320(7244):1221-2.

 

Treating hyperhidrosis. Iontophoresis should be tried before other treatments.

 

Murphy R, Harrington CI.

 

Publication Types:

Comment

Letter

 

PMID: 11202931 [PubMed - indexed for MEDLINE]

 

 

 

72: J Thorac Cardiovasc Surg  2000 Aug;120(2):276-9

 

Needlescopic surgery for palmar hyperhidrosis.

 

Yamamoto H, Kanehira A, Kawamura M, Okada M, Ohkita Y.

 

Department of Surgery, Division II, Kobe University School of Medicine, Kobe,

Japan. hideyama@mua.biglobe.ne.jp

 

OBJECTIVE: The aim of this study was to develop a less invasive technique for

video-assisted thoracic sympathectomy. METHODS: A newly designed trocar was

used. A skin incision of 2.0 to 2.5 mm in length was made in the third or fourth

intercostal space at the midaxillary line. After insertion of the trocar,

thoracic sympathectomy with electrocautery was carried out at the level of the

second and third ribs. RESULTS: From October 1998 to March 1999, 180 patients

with palmar hyperhidrosis underwent this technique. No complications related to

the technique occurred, and within 1 week the operative wound had almost

completely disappeared. There were recurrences necessitating reapplication of

the technique. CONCLUSION: The technique allowed healing without a scar and

improved the patient's cosmesis.

 

PMID: 10917942 [PubMed - indexed for MEDLINE]

 

 

 

73: Surg Laparosc Endosc Percutan Tech  2000 Aug;10(4):226-9

 

Video-assisted transthoracic sympathectomy in the treatment of primary

hyperhidrosis: friend or foe?

 

Fredman B, Zohar E, Shachor D, Bendahan J, Jedeikin R.

 

Department of Anesthesiology and Critical Care, Meir Hospital, Kfar Saba,

Israel.

 

The authors hypothesize that palmar hyperhidrosis is a systemic manifestation of

abnormal sudomotor function; consequently, thoracoscopic sympathectomy to

alleviate symptoms in the hands may result in heat dissipation because sweating

is transferred to other sites. To investigate this phenomenon and to determine

whether it adversely affects patient satisfaction, a standard questionnaire was

administered to 626 patients who underwent sympathectomy at a

university-associated public hospital between 1991 and 1998; only patients

treated at least 6 months before questionnaire distribution were included in the

study. Replies were received from 336 (53.7%) individuals. The surveyed patients

underwent bilateral T2, T3 (palmar sweating), or T3, T4 (axillary sweating)

sympathectomy by a standard video-assisted transthoracic technique. Main outcome

measures included the incidence of dry hands, compensatory sweating, chest pain,

upper-limb muscle weakness, shortness of breath, and gustatory phenomena; in

addition, patient perception of the success of the surgical procedure was

assessed. After sympathectomy, 97.3% (P < 0.0001) and 29.2% (P < 0.001) of

patients reported significant improvement in palmar hyperhidrosis and axillary

sweating, respectively. Postsurgery, severe compensatory sweating was

experienced in 90% of patients (P < 0.0001). The sites of compensatory sweating

were the back (75%), abdomen (51%), feet (23%), groin and thigh (13%), chest

(13%), and axillae (8%). Transient whole-body sweating for no apparent reason

was experienced in 30% of patients. Thirty-seven patients (11%) regretted having

undergone the surgical procedure. In contrast, 25% and 64% of patients were

either satisfied or very satisfied with the outcome of the procedure. From the

survey results, the authors conclude that palmar hyperhidrosis is a systemic

manifestation of abnormal sudomotor function and that thoracic sympathectomy may

alleviate symptoms in a large proportion of patients. However, for some

individuals, compensatory sweating may prove to be an equally troublesome

handicap. Because the occurrence of severe compensatory sweating is

unpredictable, a reversible sympathectomy may be desirable.

 

PMID: 10961751 [PubMed - indexed for MEDLINE]

 

 

 

74: Dtsch Med Wochenschr  2000 Jul 7;125(27):817-21

 

[The indications for and results of video thoracoscopic sympathectomy]

 

[Article in German]

 

Heuberger J, Furrer M, Habicht J, Inderbitzi R.

 

Lungenzentrum Hirslanden, Zurich.

 

BACKGROUND AND OBJECTIVES: Thoracoscopic sympathectomy, for years an effective

way to treat mainly palmar and axilla hyperhidrosis, experienced a revival since

the application of the principles of minimally invasive surgery. We report the

personal experiences of three surgeons with this technique, as well as patients'

view of the outcome. PATIENTS AND METHODS: Between January 1990 and November

1997, 73 procedures were performed in 43 patients (23 males, 20 females, mean

age 38.1 years, range 15-82 years), and the outcome was prospectively studied.

Palmar hyperhidrosis without axilla symptoms was the indication for the

operation in 27 patients (54 sympathectomies), Raynaud's syndrome in 15 (18

sympathectomies), and causalgia in one. Thoracic ganglia 2-4 were always

completely resected. Perioperative morbidity as well as patient satisfaction in

the long-term course (standardized interview) 25.8 (1-77) months postoperatively

were assessed. RESULTS: The complication rate in all 73 sympathectomies was

8.2%. Only two severe incidents were observed: in one patient intermittent

Horner's syndrome (1.4%) occurred, and in another severe bleeding required

conversion to open surgery (1.4%). Both complications occurred in the early

study phase. The initial success rate in all 27 patients with hyperhidrosis was

100%. In 30% of these cases a mild partial relapse was observed, which did not

interfere with their daily activities. 53% of the patients reported compensatory

and 23% gustatory sweating. 9% would have refused the operation, had they known

these side effects. In all patients with Raynaud's disease the ulcerations

healed completely. At the time of the interview, two patients (13%) complained

of painless relapses. They too stated that they had refused the operation, if

they had known about the relapses. CONCLUSIONS: Even in the longer-term course,

thoracoscopic sympathectomy is rated subjectively successful by 93% of patients

after treatment of hyperhidrosis of the upper extremities, and by 87% of

patients after treatment of Raynaud's disease, despite some untoward effects and

partial relapses.

 

PMID: 10929535 [PubMed - indexed for MEDLINE]

 

 

 

75: Ann Thorac Surg  2000 Jul;70(1):240-2

 

Needlescopic thoracic sympathectomy: treatment for palmar hyperhidrosis.

 

Goh PM, Cheah WK, De Costa M, Sim EK.

 

Minimally Invasive Surgical Center, Department of Surgery, National University

Hospital, Singapore. surgohmy@nus.edu.sg

 

BACKGROUND: Open thoracic sympathectomy has been the established option for

patients with essential hyperhidrosis. Recently, video-assisted endoscopic

sympathectomy has provided a simple, safe, reliable, and cost-effective

alternative to the earlier technique. With advances in instrumentation,

performing the procedure through 2-mm and 3-mm needlescopic ports is now

possible. The authors evaluate the effectiveness of so-called needlescopic

thoracic sympathectomy for the treatment of primary hyperhidrosis. METHODS:

Thirty five consecutive patients with a mean age of 24 years, including 23 men

and 12 women, underwent bilateral needlescopic thoracic sympathectomies at the

National University Hospital of Singapore. RESULTS: The mean operative duration

was 56 minutes, and the mean hospital stay was 1.2 days. In no patient did

Horner's syndrome or significant pneumothorax develop. The rate of success,

defined as completely dry hands, was 97%. Two patients had unilateral

recurrences that responded well to repeat needlescopic sympathectomies. We

performed a total of 72 sympathectomies. CONCLUSIONS: Our study demonstrates

that the use of miniature port access sites produces excellent medical and

cosmetic results and is associated with a short hospital stay and low risk of

complications.

 

Publication Types:

Clinical Trial

 

PMID: 10921715 [PubMed - indexed for MEDLINE]

 

 

 

76: Ann Thorac Surg  2000 Jul;70(1):314-7

 

Thoracoscopic sympathectomy for hyperhidrosis palmaris: a periareolar approach.

 

Kesler KA, Brooks-Brunn JA, Campbell RL, Brown JW.

 

Department of Surgery, Indiana University School of Medicine, Indianapolis

46202, USA. kkesler@iupui.edu

 

Severe hyperhidrosis palmaris represents a disabling problem for many patients.

Thoracoscopic techniques that involve dissection and removal of the upper

thoracic sympathetic chain are believed to result in the lowest incidence of

recurrent symptoms. However, aside from an axillary incision, an additional

upper anterior chest wall approach is usually required. Over the past 2 years,

we have used a periareolar incision in eight patients to improve postoperative

cosmesis for this benign condition.

 

PMID: 10921742 [PubMed - indexed for MEDLINE]

 

 

 

77: Eur J Cardiothorac Surg  2000 Jul;18(1):7-11

 

Early and long-term complaints following video-assisted thoracoscopic surgery:

evaluation in 173 patients.

 

Stammberger U, Steinacher C, Hillinger S, Schmid RA, Kinsbergen T, Weder W.

 

Division of Thoracic Surgery, University Hospital, Ramistrasse 100, CH-8091,

Zurich, Switzerland.

 

OBJECTIVE: Minimal invasive surgical techniques have gained high acceptance in

thoracic surgery during the last 10 years. However, up to now, only scant

information exists on chronic postoperative pain and discomfort in patients who

underwent video-assisted thoracoscopy. Therefore, a retrospective study was

performed with the aid of a self-reported questionnaire. METHODS: Two hundred

and thirteen patients (of whom 79 females) with a mean age of 48 (range 15-88)

years were operated on for a total of 225 procedures. Thoracoscopy was performed

for pneumothorax (n=70), pulmonary nodules (n=44), interstitial lung diseases

(n=20), pleural effusion (n=20), and empyema (n=19). Various indications

included therapeutic or diagnostic procedures in bullous disease, mediastinal

tumors, carcinoma, inflammatory lung disease, hyperhidrosis mani and

bronchiectasis. RESULTS: Mean drainage time was 6.0+/-4.7 days and hospital stay

8.4+/-6.6 days. One patient died on the ninth postoperative day after lobectomy

for bronchial carcinoma due to cardiac failure, five patients needed a short

period of reintubation due to acute respiratory failure. In two patients,

thoracoscopic reoperation was necessary for closure of bronchopleural fistula.

The self-reported questionnaire was returned by 173 (81%) of all patients within

a mean follow-up of 18 (3-38) months. More than half of the patients (53%)

reported no thoracic pain as early as 2 weeks after the procedure. At 2 weeks

after the operation, 13% of patients suffered from localized pain and 31% from

diffuse discomfort. Twelve percent needed pain medication regularly, and 3%

occasionally. At 6 months postoperatively, three quarters of the patients had no

complaints, 5% suffered from scar pain, and 20% had diffuse chest discomfort.

One year after the procedure, 86% of the patients had no complaints, 9% suffered

from minimal pain, and 5% from moderate pain. Two years after the procedure, 96%

of the patients had no complaints at all. One hundred and twenty-five of the 140

patients (89%) working preoperatively went back to work within 2 weeks after the

operation. Fifteen patients did not work between 3 and 16 weeks; 14 due to chest

pain, one due to shoulder pain. CONCLUSION: Video-assisted thoracoscopy permits

very early recovery with rapid reintegration into the working process. Long-term

complaints after videothoracoscopy are rare.

 

PMID: 10869933 [PubMed - indexed for MEDLINE]

 

 

 

78: Surg Neurol  2000 Jul;54(1):96-7

 

Comment on:

 Surg Neurol. 1999 Nov;52(5):453-7.

 

Transthoracic endoscopic sympathectomy.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 11203125 [PubMed - indexed for MEDLINE]

 

 

 

79: Circulation  2000 Jun 13;101(23):2716-20

 

Sympathetic denervation of the upper limb improves forearm exercise performance

and skeletal muscle bioenergetics.

 

Kardos A, Taylor DJ, Thompson C, Styles P, Hands L, Collin J, Casadei B.

 

University Department of Cardiovascular Medicine, University of Oxford, UK.

 

BACKGROUND: Sympathetic activation may limit exercise performance by restraining

muscle blood flow or by negatively affecting skeletal muscle metabolic behavior.

To test this hypothesis, we studied the effect of thoracoscopic sympathetic

trunkotomy (TST) on forearm exercise duration, blood flow, and muscle

bioenergetics in 13 patients with idiopathic palmar hyperhidrosis. METHODS AND

RESULTS: Heart rate and beat-by-beat mean arterial pressure were recorded at

rest and during right and left rhythmic handgrip before and 4 to 7 weeks after

right TST. Forearm blood flow was measured bilaterally at rest and on the right

during exercise. Right forearm muscle phosphocreatine content and intracellular

pH were assessed by (31)phosphorus magnetic resonance spectroscopy. After right

TST, exercise duration increased from 8.9+/-1.4 to 13.4+/-1.8 minutes (P<0.0001)

with the right forearm and from 5.7+/-0.4 to 7.6+/-0.9 minutes (P<0.05) with the

left (P<0.05 for the interaction between treatment and side). Right forearm

blood flow at rest was 66% higher (P<0.01) after right TST, but this difference

decreased as the exercise progressed. After right TST, a significant reduction

occurred in muscle acidification and phosphocreatine depletion during

ipsilateral forearm exercise. This was associated with a significantly reduced

mean arterial pressure response to right handgrip, whereas the pressor response

to left handgrip did not change. CONCLUSIONS: Sympathetic denervation of the

upper limb significantly improves forearm skeletal muscle bioenergetics and

exercise performance in patients with idiopathic palmar hyperhidrosis.

 

PMID: 10851209 [PubMed - indexed for MEDLINE]

 

 

 

80: Eur J Cardiothorac Surg  2000 Jun;17(6):691-6

 

Comment in:

 Eur J Cardiothorac Surg. 2001 Jun;19(6):951-2.

 

Ultra-thin needle thoracoscopic surgery for hyperhidrosis with excellent

cosmetic effects.

 

Sung SW, Kim YT, Kim JH.

 

Department of Thoracic and Cardiovascular Surgery, Seoul National University

Hospital, 28 Yongon, Chongno, 110-744, Seoul, South Korea. swsung@snu.ac.kr

 

BACKGROUND: In spite of its cosmetic benefits over open surgical techniques,

endoscopic sympathectomy using 5 mm or larger instruments still has the problems

of operative scar as well as pain on the trocar sites. Recently we have begun

using 2 mm endoscopic instruments. The purpose of this study was to confirm the

safety and feasibility of fine needle endoscopic instruments in thoracic

sympathetic ablation. METHODS: We have exclusively used 2 mm endoscopic

instruments since January 1997, and from that time to May 1999 417 patients were

underwent surgical procedures for hyperhidrosis. T2 or T2/T3 sympathectomy was

performed for the first 56 patients, after June 1997, in 361 patients the

interconnecting sympathetic trunk was divided instead of ganglion resection, and

this procedure was named sympathicotomy. Palmar hyperhidrosis was presented in

375 patients (89.9%) and facial in 28 (6.7%) and axillary in 14 (3.4%). The

level of division or resection of the ganglion differed according to the

patient's symptoms. RESULTS: Sympathicotomy and sympathectomy were successful

and all patients were satisfied with immediate dryness of affected sites. There

were not any cases of bleeding or reoperation or hospital mortality. A large

endoscope was required to eliminate the pleural adhesion in fourteen cases

(7.7%). Thoracotomy conversion was required in two pleural adhesion cases. Minor

complications were occurred in 17 patients (4.1%); such as closed thoracostomy

in ten cases, peripheral nerve injury in three, pulmonary parenchymal injury in

two, Horner's syndrome in two and atrial fibrillation in one. We have five cases

of recurrent symptoms (1.2%). CONCLUSION: Our experience indicates that, for the

treatment of hyperhidrosis, 2 mm ultra-thin needle endoscopic instruments are

safe and effective to operate on palmar and facial hyperhidrosis patients.

 

PMID: 10856861 [PubMed - indexed for MEDLINE]

 

 

 

81: Eur J Cardiothorac Surg  2000 Jun;17(6):697-701

 

Comment in:

 Eur J Cardiothorac Surg. 2001 Apr;19(4):545-6.

 

'Needlescopic' video-assisted thoracic surgery for palmar hyperhidrosis.

 

Yim AP, Liu HP, Lee TW, Wan S, Arifi AA.

 

Division of Cardio-thoracic Surgery, The Chinese University of Hong Kong, Prince

of Wales Hospital, Shatin, N.T., People's Republic of, Hong Kong, China.

yimap@cuhk.edu.hk

 

OBJECTIVE: The video-assisted thoracic surgery (VATS) approach for thoracodorsal

sympathectomy has been well accepted. We report the use of ultra-fine

thoracoscopic equipment for this procedure, based on the experience from two

centers in Asia. MATERIALS AND METHODS: Thirty-eight patients with palmar

hyperhidrosis underwent bilateral VATS thoracodorsal sympathectomy using 2-mm

instruments exclusively. General anesthesia with selective one lung ventilation

was used. Carbon dioxide insufflation was used when lung collapse was found to

be inadequate. In 11 patients, the sympathetic chain was excised (T2-T3 for

palmar hyperhidrosis alone, extending to T4 for axillary hyperhidrosis), and in

27 patients, the chain was cauterized. The choice of procedure reflects the

surgeon's preference. No chest drains were left after the procedure and no

stitching of the wound was necessary. RESULTS: There was no mortality or major

complications. A small pneumothorax was found in the postoperative chest X-ray

in three patients. They all resolved without further intervention. Twenty-seven

patients were discharged on the same day of admission, and 11 patients were

discharged on postoperative day one. After an average follow-up of 16 months

(range 5-28), there has been no recurrence of symptoms. Compensatory truncal

hyperhidrosis was encountered in two patients, but the symptoms were not severe

enough to interfere with lifestyle, and this required no further treatment.

CONCLUSION: Thoracodorsal sympathectomy using 2-mm instruments is technically

feasible and is associated with an excellent clinical outcome. Limitations of

the equipment, however, exist (narrow field of vision, lower resolution and

difficulty in maintaining fine control), and we are currently restricting its

use to relatively simple procedures.

 

Publication Types:

Clinical Trial

 

PMID: 10856862 [PubMed - indexed for MEDLINE]

 

 

 

82: Harefuah  2000 Jun 1;138(11):913-6, 1008

 

[Videothorascopic sympathectomy (VATS) for palmar hyperhidriosis:summary of a

clinical trial and surgical results]

 

[Article in Hebrew]

 

Nesher N, Galili R, Sharony R, Uretzky G, Saute M.

 

Dept. of Cardiothoracic Surgery, Lady Davis-Carmel Medical Center, Haifa.

 

Palmar hyperhidriosis is not a life-threatening disease but leads to loss in the

quality of life. Conservative treatment is ineffective and major surgery

involves perioperative complications and esthetic impairment. From 1992 to 1998

we treated 156 patients with palmar hyperhidriosis using a single port,

drainless videothoracoscopic procedure with almost no complications.

 

Publication Types:

Clinical Trial

 

PMID: 10979397 [PubMed - indexed for MEDLINE]

 

 

 

83: J Formos Med Assoc  2000 Jun;99(6):466-71

 

Thermographic study of palmar and facial skin temperature of hyperhidrosis

patients before and after thoracic sympathectomy.

 

Tsai JC, Lim KB, Lin SY, Kao MC.

 

Laser Medicine Research Center, College of Medicine, National Taiwan University,

Taipei, Taiwan.

 

PURPOSE: The purpose of this study was to investigate the roles of the second

thoracic sympathetic segment in the sympathetic innervation of the hands and

face, and to compare skin temperature changes in the palms, fingers, face, and

neck of palmar hyperhidrosis (PH) patients before and after endoscopic thoracic

sympathectomy. METHODS: Twenty-two patients, 14 women and eight men, with severe

PH were treated with endoscopic ablation of the T2 segment. The skin

temperatures of the hands, neck, and face were assessed by infrared thermography

both before and after operation. RESULTS: All obtained satisfactory relief of

PH. Before sympathectomy, thermography revealed that the palmar skin temperature

(PST) was significantly lower than the facial temperature by 1.3 degrees C

(paired t-test, p < 0.005). After sympathectomy, thermography showed significant

elevations in temperature mainly of the thenars, palms, digits, and nose, but

not of the forehead, mandible, or neck (ANOVA, p < 0.05 with Bonferroni t-test).

The variations in PST among PH patients were much greater preoperatively than

postoperatively. More prominent postoperative PST elevation was found in PH

patients with lower preoperative PST (r = 0.898, p < 0.001). CONCLUSIONS: These

findings demonstrate that the T2 segment is the key source of sympathetic

innervation to the hand and that the T2 segment contributes only trivial

sympathetic innervation to the face. The results of the present thermography

studies offer descriptive information about the autonomic innervation of the

upper thoracic sympathetic trunk.

 

PMID: 10925552 [PubMed - indexed for MEDLINE]

 

 

 

84: Neurol Res  2000 Jun;22(4):420-4

 

Histopathological examination of chemo-sympathectomy in cats.

 

Wang YC, Lee WH, Chen WY, Fu YM.

 

Department of Neurosurgery, Taichung Veterans General Hospital, Taiwan, ROC.

ycwang@vghtc.vghtc.gov.tw

 

In recent decades, there has been an increase in both the number of

sympathectomy techniques, as well as the surgical findings of sympathetic

anatomy. Currently the advanced technique of C-arm guided percutaneous thoracic

chemo-sympathectomy is widely used for the treatment of palmar hyperhidrosis.

However, a better understanding of chemical agents in sympathectomy is required.

In this study, chemo-sympathectomy was performed in cats, using alcohol,

glycerol and various concentrations of phenol, to determine the chronic

neurotoxic effects of these chemical agents on the stellate ganglia. The

stellate ganglia of 24 cats were exposed under endotracheal general anesthesia,

then injected with about 0.02 ml of absolute alcohol, glycerol and phenol (10%,

25%, 50%, and 75% concentration) solutions, respectively. The stellate ganglia

were taken for histological examination three weeks after the chemical

injection. The results showed that the degenerative changes in the cytoplasm and

nucleus of ganglionic cells and intercellular tissue were moderate and

relatively moderate after the injection of alcohol and glycerol, respectively.

Meanwhile, the stellate ganglia revealed mild, relatively moderate, serious and

extremely serious degeneration after injection of 10%, 25%, 50%, and 75% phenol,

respectively. In conclusion, we recommend a high concentration of phenol, in the

least volume, as a chemical agent for clinical injection in the upper thoracic

sympathetic ganglion.

 

PMID: 10874694 [PubMed - indexed for MEDLINE]

 

 

 

85: Neurosurgery  2000 May;46(5):1254-7; discussion 1257-8

 

Comment in:

 Neurosurgery. 2001 Mar;48(3):702.

 

Microinvasive transaxillary thoracoscopic sympathectomy: technical note.

 

Wahlig JB Jr, Welch WC, Weigel TL, Luketich JD.

 

Department of Neurological Surgery, University of Pittsburgh, Presbyterian

University Hospital, Pennsylvania 15213, USA.

 

OBJECTIVE: To describe a two-port transaxillary thoracoscopic approach for

thoracic sympathectomy that maximizes working space, improves manipulative

ability, and enhances visualization of the surgical field. METHODS: Positioning

of the patients was optimized to displace the scapula posteriorly, widen the

avenue of approach to the sympathetic ganglia, and create a more direct route to

the target. The semi-Fowler position permitted the lung apex to fall away from

mediastinal structures, obviating a separate retraction port. A 30-degree

endoscope allowed an unobstructed view of surgical progress, and anatomic

relationships were manipulated in a temporal sequence to facilitate dissection.

RESULTS: Microinvasive transaxillary sympathectomy was performed successfully in

13 patients, all of whom had a good outcome without complications. CONCLUSION:

The modifications implemented increase the speed and safety of thoracoscopic

sympathectomy while minimizing complications.

 

PMID: 10807262 [PubMed - indexed for MEDLINE]

 

 

 

86: Neurosurgery  2000 Apr;46(4):924-8

 

Uniportal endoscopic superior thoracic sympathectomy.

 

Vanaclocha V, Saiz-Sapena N, Panta F.

 

Division of Neurosurgery, Clinica Universitaria, University of Navarra,

Pamplona, Spain.

 

OBJECTIVE: A retrospective study presenting our experience with upper thoracic

endoscopic sympathectomy in patients with primary palmar hyperhidrosis. METHODS:

One hundred patients (46 women and 54 men) underwent bilateral uniportal

endoscopic thoracic sympathectomy since January 1, 1995. Age distribution ranged

from 12 to 54 years (mean, 23.4 yr). RESULTS: Sympathectomy on both sides was

accomplished within 30 minutes in a single stage. Ninety-six patients (96%) had

an uneventful postoperative course and were discharged the following day. Four

patients with residual hemothorax required intercostal drainage and were

discharged on the third postoperative day. Ninety-six patients were completely

satisfied with immediate and permanent relief of palmar perspiration.

Compensatory hyperhidrosis was the major complication, which was usually mild

and tolerable after reassurance. In only eight patients (8%) was the

compensatory hyperhidrosis considered bothersome, requiring treatment with

aluminum chloride in ethanol solution at 25%. There was no mortality. Recurrence

of palmar hyperhidrosis has been noticed in five patients (5%) during the

follow-up period (range, 2-56 mo; mean, 12 mo). At the time of reoperation, a

remaining branch of the sympathetic chain could be observed and coagulated.

CONCLUSION: We consider thoracoscopic sympathectomy to be a simple, safe, and

effective method for treating palmar hyperhidrosis. It is an effective method

for treating patients with palmar hyperhidrosis, with a shorter operation time,

fewer hospital days, and a better cosmetic result, as compared with the open

approaches.

 

PMID: 10764266 [PubMed - indexed for MEDLINE]

 

 

 

87: Dtsch Med Wochenschr  2000 Mar 10;125(10):290

 

[Essential hyperhidrosis]

 

[Article in German]

 

Wollina U.

 

Klinik fur Dermatologie und Allergologie der Friedrich-Schiller-Universitat,

07740 Jena. uwol@derma.uni-jena.de

 

Publication Types:

Review

Review, Tutorial

 

PMID: 10755853 [PubMed - indexed for MEDLINE]

 

 

 

88: Arch Dermatol  2000 Mar;136(3):393-9

 

Hypnosis in dermatology.

 

Shenefelt PD.

 

Department of Internal Medicine, College of Medicine, University of South

Florida, Tampa 33612, USA. pshenefe@hsc.usf.edu

 

BACKGROUND: Hypnosis is an alternative or complementary therapy that has been

used since ancient times to treat medical and dermatologic problems. OBJECTIVE:

To describe the various uses for hypnosis as an alternative or complementary

therapy in dermatologic practice. METHODS: A MEDLINE search was conducted from

January 1966 through December 1998 on key words related to hypnosis and skin

disorders. RESULTS: A wide spectrum of dermatologic disorders may be improved or

cured using hypnosis as an alternative or complementary therapy, including acne

excoriee, alopecia areata, atopic dermatitis, congenital ichthyosiform

erythroderma, dyshidrotic dermatitis, erythromelalgia, furuncles, glossodynia,

herpes simplex, hyperhidrosis, ichthyosis vulgaris, lichen planus,

neurodermatitis, nummular dermatitis, postherpetic neuralgia, pruritus,

psoriasis, rosacea, trichotillomania, urticaria, verruca vulgaris, and vitiligo.

CONCLUSION: Appropriately trained clinicians may successfully use hypnosis in

selected patients as alternative or complementary therapy for many dermatologic

disorders.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 10724204 [PubMed - indexed for MEDLINE]

 

 

 

89: Biol Psychol  2000 Feb;52(1):85-90

 

Nonresponders among hyperhidrotics.

 

Kerassidis S, Charistou A.

 

Department of Basic Sciences, Laboratory of Functional Brain Imaging, Division

of Medicine, School of Health Sciences, University of Crete, Greece.

eploropo@otenet.gr

 

In the context of our investigation on palmar sweating and hyperhidrosis we

subjected 40 individuals (20 hyperhidrotic and 20 normal) to noise stimulation.

The participants received ten startling auditory tones (square pulse of 400 ms

duration, 1000 Hz frequency and 105-dB intensity) at random intervals varying

from 15-55 s. Hyperhidrotic subjects, relative to controls, responded with

greater amplitude and habituated later, but a subset of these subjects failed to

respond at all to the tone. In this report, we focus on the finding that some

hyperhidrotics were nonresponders. We discuss the consequences of this finding,

both its implication for understanding hyperhidrosis and nonresponsiveness, as

well as the complexity of sympathetic nervous system activation.

 

PMID: 10686374 [PubMed - indexed for MEDLINE]

 

 

 

90: Ear Nose Throat J  2000 Feb;79(2):111-2

 

Gustatory sweating syndrome of the submandibular gland.

 

Persaud NA, Myer CM 3rd, Rutter MJ.

 

Department of Otolaryngology, Metropolitan Hospital, Grand Rapids, Mich. 49506,

USA.

 

Gustatory sweating syndrome involving the submandibular gland is rare. We

present a case of a patient who experienced this syndrome 5 years after

undergoing submandibular gland resection. Our patient was satisfied simply with

an explanation of the disorder and reassurance. But in cases where further

intervention is sought, medical and surgical options are available and should be

individualized for the patient.

 

PMID: 10697935 [PubMed - indexed for MEDLINE]

 

 

 

91: Kyobu Geka  2000 Feb;53(2):136-40

 

[Ineffective and recurrent cases of thoracoscopic sympathectomy for

hyperhidrosis and intractable pain]

 

[Article in Japanese]

 

Hoshina K, Amemiya R, Asato Y, Hishikawa S, Nemoto K, Kiyoshima M, Kohno S,

Shida D, Tanaka R, Suzuki A, Yoshimi F, Koizumi S.

 

Department of Surgery, Ibaraki Prefectural Central Hospital and Cancer Center,

Japan.

 

We reported the cases of thoracoscopic sympathectomy, that is, six cases of

hyperhidrosis, three of post herpetic neuralgia, and four of reflex sympathetic

dystrophy, including recurrent or incompletely resected or ineffective ones.

Recently this procedure for hyperhidrosis had been performed frequently because

of its effectiveness, less pain, early discharge and cosmetic aspect. For an

ineffective case of hyperhidrosis abdominal respiration which emphasized the

exhalation and using an upper abdomen decreased the sweating. The balance of

autonomic nerve system, toward parasympathetic dominant, was thought to be

improved by conscious respiration. The decrease of sweating right after the

operation in a case of incomplete resection indicated that intraoperative

maneuver could restrict the sympathetic nerve. This procedure for a pain control

could be less effective than that for hyperhidrosis, so an adequate preoperative

informed consent was thought to be necessary.

 

PMID: 10667025 [PubMed - indexed for MEDLINE]

 

 

 

92: Surg Endosc  2000 Feb;14(2):134-6

 

Repeat transthoracic endoscopic sympathectomy for palmar and axillary

hyperhidrosis.

 

Lin TS, Fang HY, Wu CY.

 

General Thoracic Surgery, Changhua Christian Hospital, No. 135, Nan-Siau Street,

Changhua City, Taiwan, ROC.

 

BACKGROUND: Patients undergoing an unsuccessful sympathectomy experience dryness

on one hand and excessive sweating on the other. This is embarrassing for the

patients, and resolution of both a previous failed sympathectomy and recurrent

hyperhidrosis is important. METHODS: From September 1995 to January 1998, 24

patients (11 men and 13 women; mean age, 28.2 years) underwent repeat

transthoracic sympathectomy (TES). The repeat TES was performed with patients

under general anesthesia using either a standard single-lumen endotracheal tube

(12 patients) or a double-lumen endotracheal tube (12 patients). Ablation of T2

and T3 ganglia and any Kuntz fiber was performed in treating patients with

palmar hyperhidrosis, and a similar procedure was performed on T3 and T4 ganglia

for patients with axillary hyperhidrosis. RESULTS: The reasons for failure of

the previous TES were pleural adhesion (14/24), intact T2 ganglion (5/24),

aberrant venous arch drainage to the superior vena cava (2/24), incomplete

interruption of sympathetic nerve (2/24), and possible reinnervation (1/24). The

mean operation time was 28 min (range, 18-72 min). In all, 23 patients had a

satisfactory result, without recurrence of palmar or axillary hyperhidrosis. The

mean follow-up time was 22 months (range, 5-30 months). The average hospital

stay was 1.8 days. There was no surgical mortality. CONCLUSION: Repeat TES is a

safe and effective method for treating both an unsuccessful sympathectomy and

recurrent palmar or axillary hyperhidrosis.

 

PMID: 10656945 [PubMed - indexed for MEDLINE]

 

 

 

93: Surg Laparosc Endosc Percutan Tech  2000 Feb;10(1):5-10

 

Comment in:

 Surg Laparosc Endosc Percutan Tech. 2000 Oct;10(5):338-9.

 

Endoscopic thoracic sympathectomy for treatment of essential hyperhidrosis

syndrome: experience with 650 patients.

 

Reisfeld R, Nguyen R, Pnini A.

 

The Center for Hyperhidrosis at The Beverly Hills Center for Special Surgery,

Los Angeles, California 90035, USA.

 

Patients with essential hyperhidrosis (EH) syndrome may experience subjective

suffering and social/occupational challenges. We examined the safety and

efficacy of minimally invasive endoscopic surgery for treating EH. Single

bilateral incisions, followed by endoscopic thoracic sympathectomy

(ETS)-mediated bilateral ablation of the T2 sympathetic ganglia, were used to

treat 650 patients with a primary diagnosis of palmar (90%) or facial

hyperhidrosis (10%). Palmar and facial hyperhidrosis were resolved in 584 of 585

(>99%) and 62 of 65 (95%) patients, respectively. Surgery required less than 1

hour, and no patient experienced a life-threatening adverse event. Compensatory

sweating was observed in 83% of patients and was considered mild or moderate in

approximately 67% of those patients. Innovations in ETS have resulted in

minimally invasive, highly efficient, safe treatment of EH. Surgery is minimally

intrusive to patients, who were usually discharged within 2 hours after surgery

and able to resume normal activities within 1 week.

 

PMID: 10872518 [PubMed - indexed for MEDLINE]

 

 

 

94: Acta Neurochir (Wien)  2000;142(6):691-6

 

Endoscopic transthoracic sympathicotomy affects the autonomic modulation of

heart rate in patients with palmar hyperhidrosis.

 

Wiklund U, Koskinen LO, Niklasson U, Bjerle P, Elfversson J.

 

Department of Biomedical Engineering & Informatics, University Hospital, Umea,

Sweden.

 

BACKGROUND: Palmar hyperhidrosis has been associated with an increased activity

of the sympathetic nervous system. The objective of this study was to assess the

immediate and long-term effects of endoscopic transthoracic sympathicotomy on

the autonomic modulation of the heart rate in patients with palmar

hyperhidrosis. METHODS: Power spectrum analysis of heart rate variability in the

lying position and after passive tilt to the upright position was performed in

thirteen patients the day before and after sympathicotomy. A follow-up recording

was performed in ten patients approximately six months later. Recordings from 26

healthy subjects were used as a reference group. FINDINGS: The patients had a

tendency to higher power of the low-frequency (LF: 0.04-0.15 Hz) and

high-frequency (HF; above 0.15 Hz) components than controls in the upright

position. After sympathicotomy LF power was reduced, but HF power was unchanged.

At follow-up LF power remained at a lower level, but now HF power was reduced.

INTERPRETATION: Patients with palmar hyperhidrosis have a sympathetic

overactivity but also a compensatory high parasympathetic activity.

Sympathicotomy results in an initial sympathovagal imbalance with a

parasympathetic predominance, which is restored on a long-term basis.

 

PMID: 10949445 [PubMed - indexed for MEDLINE]

 

 

 

95: Ann Thorac Surg  2000 Jan;69(1):251-3

 

Needle thoracic sympathectomy for essential hyperhidrosis: intermediate-term

follow-up.

 

Lee DY, Yoon YH, Shin HK, Kim HK, Hong YJ.

 

Respiratory Center, Department of Thoracic and Cardiovascular Surgery, Yongdong

Serverance Hospital, Yonsei University College of Medicine, Seoul, Korea.

dylee@yumc.yonsei.ac.kr

 

BACKGROUND: Essential hyperhidrosis is a condition with excessive sweating

localized to certain part of the body. A definitive cure can be obtained by

upper thoracic sympathectomy. METHOD: Between June and October 1997, 117

patients with essential hyperhidrosis underwent needle thoracoscopic

sympathectomy. Of the 94 patients, 42 were men and 52 women. Their ages ranged

from 14 to 63 years, with a mean age of 23 years. RESULTS: There were no

mortality or life-threatening complications. Symptomatic improvement was found

in 95.7%. Compensatory hyperhidrosis was found in 71.2% of the patients, but in

these compensatory hyperhidrosis were mostly tolerable. CONCLUSIONS: This

therapeutic procedure is minimally invasive and very effective. Further

development of the new device and surgical technique are expected to follow.

 

PMID: 10654524 [PubMed - indexed for MEDLINE]

 

 

 

96: Aust N Z J Surg  2000 Jan;70(1):57-9

 

Skin wrinkling for the assessment of sympathetic function in the limbs.

 

Vasudevan TM, van Rij AM, Nukada H, Taylor PK.

 

Department of Vascular Surgery, Dunedin Hospital, University of Otago Medical

School, New Zealand.

 

BACKGROUND: Wrinkling of the skin of the palm and sole is considered to be

dependent on the presence of intact sympathetic nervous activity. Loss of

sympathetic integrity could be simply and usefully assessed by the absence of

wrinkling. To test this hypothesis, the skin wrinkle test was compared with the

starch-iodine sweat test and sympathetic skin response (SSR) in patients with

abnormal sympathetic function. METHODS: The three tests were carried out in 34

patients (68 limbs) undergoing temporary or permanent disruption of the

sympathetic chain to upper or lower limbs. Included in this group were six

diabetics undergoing chemical or surgical sympathectomy, lumbar epidural

infusions following vascular surgery, and patients for whom sympathectomy was

being considered. Sensitivity and specificity analysis and predictive values of

the wrinkling response and the starch-iodine test were related to the SSR as the

standard. RESULTS: The wrinkle test showed a sensitivity of 97% and specificity

of 95%, and bore good correlation to the SSR. The starch-iodine test showed

sensitivity of 55% and specificity of 93%. A hypothesis for the mechanism of

wrinkling based on the observations of the present study is proposed.

CONCLUSION: The wrinkle test is a reliable test of sympathetic function, is

inexpensive and is easy to perform at the bedside. The sweat gland

myo-epithelial cells and absence of sebum could play an important role in the

wrinkling response. It can be used to select patients who will benefit from

sympathectomy, and can adequately evaluate sympathetic blockade.

 

PMID: 10696945 [PubMed - indexed for MEDLINE]

 

 

 

97: Br J Dermatol  2000 Jan;142(1):194-5

 

A caution about surgical treatment for facial blushing.

 

Drummond PD.

 

Publication Types:

Letter

 

PMID: 10819557 [PubMed - indexed for MEDLINE]

 

 

 

98: Eur J Surg  2000 Jan;166(1):65-9

 

Comment in:

 Eur J Surg. 2001 Mar;167(3):237-8.

 

Operative monitoring of hand and axillary temperature during endoscopic superior

thoracic sympathectomy for the treatment of palmar hyperhidrosis.

 

Saiz-Sapena N, Vanaclocha V, Panta F, Kadri C, Torres W.

 

Department of Anaesthesiology, Clinica Universitaria, University of Navarra,

Pamplona, Spain.

 

OBJECTIVE: To find out how much the temperature in the palm rises after upper

thoracic sympathectomy for palmar hyperhidrosis, and correlate the temperature

with the outcome. DESIGN: Retrospective study. SETTING: University hospital,

Spain. SUBJECTS: 73 patients (34 women and 39 men, age range 16-42 years, mean

26) who were operated for palmar hyperhidrosis between 1 January 1995 and 31

December 1997. INTERVENTIONS: Bilateral thoracic endoscopic sympathectomy during

which the temperature was monitored on the skin of both axillae and thenar

eminences, and in the oesophagus. MAIN OUTCOME MEASURES: Morbidity, alleviation

of hyperhidrosis, recurrence rate, and differences in temperature

postoperatively. RESULTS: There was minor bleeding during operation in 25 cases

(34%), but in only 4 was it sufficient to require insertion of a drain; 2

patients developed transient Homer's syndrome; but the most common complication

was compensatory hyperhidrosis (n = 52, 71%). In only 5 was this other than mild

and required treatment with aluminium chloride in ethanol 25%. Palmar

hyperhidrosis was alleviated in all cases, axillary sweating was considerably

improved, and there was improvement in the feet in 56 (77%). There were 5

recurrences, all on the right side, during a mean follow up of 9 months (range

2-36), but in no case was the sweating severe. In almost all cases the

temperature of the palm was less than that of the axilla before operation by a

mean (SD) of 0.9 (0.3) degrees C. The rise in temperature varied from 1.7 (0.4)

degrees C to 2.6 (0.4) degrees C. In the 5 patients who developed recurrences

the increase was less (0.5 (0.4) degrees C). CONCLUSION: Thoracic endoscopic

sympathectomy is safe, simple, and effective in treating palmar hyperhidrosis

that has not responded to conservative treatment. Intradermal monitoring is an

accurate and cost-effective way of monitoring temperature during operation.

Although it is essential to achieve a rise in temperature of 1 degrees C, our

most important finding was that the final temperature in both hands and axillae

should be above 35 degrees C and as near as possible to 36 degrees C.

 

PMID: 10688220 [PubMed - indexed for MEDLINE]

 

 

 

99: Eur Neurol  2000;44(2):112-6

 

Cardiac autonomic function in patients suffering from primary focal

hyperhidrosis.

 

Birner P, Heinzl H, Schindl M, Pumprla J, Schnider P.

 

Division of Neurological Rehabilitation, Department of Neurology, University of

Vienna, Austria. peter.birner@akh-wien.ac.at

 

Cardiac autonomic function in patients (n = 63) with primary focal hyperhidrosis

and healthy controls (n = 28) was investigated by short-term frequency domain

power spectral analysis of heart rate variability. The power of the

very-low-frequency band (0.01-0.05 Hz) was significantly lower in patients with

axillary hyperhidrosis than in controls. No differences between groups could be

observed at investigation of the low-frequency band (0.05-0.15 Hz), which was a

surprising finding because this band represents also sympathetic cardiac

innervation. At the high-frequency band (0.15-0.5 Hz), which represents

parasympathetic cardiac innervation, an interaction of type and position

influencing spectral power was detected. Our highly interesting findings

indicate that primary focal hyperhidrosis is based on a much more complex

autonomic dysfunction than generalised sympathetic overactivity and seems to

involve the parasympathetic nervous system as well. Copyright 2000 S. Karger AG,

Basel

 

PMID: 10965164 [PubMed - indexed for MEDLINE]

 

 

 

100: Isr J Psychiatry Relat Sci  2000;37(1):25-31

 

Impairment in quality of life among patients seeking surgery for hyperhidrosis

(excessive sweating): preliminary results.

 

Amir M, Arish A, Weinstein Y, Pfeffer M, Levy Y.

 

Department of Behavioral Sciences, Ben-Gurion University of the Negev,

Beer-Sheva, Israel. Mamir@Bgumail.bgu.ac.il

 

BACKGROUND: The present paper describes the initial stages of the development

and administration of a short, disease-specific, health related questionnaire to

assess the impact of suffering from hyperhidrosis (excessive sweating) on the

Quality of Life (QoL) of patients who are anticipating surgery for this

disorder. METHOD: The study was performed in two stages: 1. The life domains in

which the condition impairs QoL were assessed by in-depth interviews with 10

patients suffering from hyperhidrosis. 2. A questionnaire covering five life

domains was built based on these interviews. 3. This questionnaire was

administered to 48 patients, 30 females and 18 males between the ages 15 and 48.

RESULTS: Results showed that subjective QoL was significantly lower among

females in four of the five life areas and that duration of the condition

correlates with a lower quality of life. A regression analysis showed that the

subjective suffering of the patients was explained mainly by social aspects.

CONCLUSIONS: The questionnaire is a novel attempt to assess QoL in a disorder

with strong esthetic and social consequences and could improve communication

between patients and their physicians.

 

PMID: 10857268 [PubMed - indexed for MEDLINE]

 

 

 

101: J Neurosurg  2000 Jan;92(1 Suppl):44-9

 

Comment in:

 J Neurosurg. 2000 Oct;93(2 Suppl):342-3.

 

Changes of bilateral palmar skin temperature in transthoracic endoscopic T-2

sympathectomy.

 

Lu K, Liang CL, Lee TC, Chen HJ, Su TM, Liliang PC.

 

Department of Neurosurgery, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.

 

OBJECT: Transthoracic endoscopic T-2 sympathectomy is currently the treatment of

choice for palmar hyperhidrosis (PH). Intraoperative monitoring of palmar skin

temperature (PST) is often used to assess the adequacy of sympathetic ablation.

The aim of this study was to investigate the time course of PST changes during

the operation and to determine factors involved in the sympathetic modulation of

the palmar skin blood flow. METHODS: Eighty-one patients with PH underwent

bilateral transthoracic endoscopic sympathectomy of T-2 in which continuous

intraoperative PST monitoring was used. Palmar skin temperature data, recorded

every 30 seconds throughout the operation, were plotted against time, and a

graph of two PST curves was obtained in each case. A multiphasic curve pattern

of great similarity was observed in nearly 70% of cases. Specific PST readings

at different operative stages were collected and averaged for all cases. The

trend of PST changes in response to different procedures during the operation

was analyzed. It was found that unilateral procedures caused simultaneous

bilateral PST alterations. In almost all cases, bilateral PST was dramatically

lowered when unilateral skin incision and intercostal muscle dissection were

performed. The temperature remained low until the T-2 sympathectomy was finished

on one side. In addition, unilateral T-2 sympathectomy induced synchronous

elevation of bilateral PST. However, the ipsilateral response was significantly

stronger than that on the contralateral side. CONCLUSIONS: Although

intraoperative monitoring of PST is a reliable guide for surgeons performing

endoscopic transthoracic sympathectomy, it is important to realize that PST

fluctuates at different stages during the operation and that surgical procedures

themselves can significantly influence PST readings. The PST data recorded at

specific time points, therefore, can be misleading in terms of accuracy and the

completeness of ablation of the target sympathetic ganglia, especially when the

sympathetic trunk or ganglia are anatomically aberrant.

 

PMID: 10616057 [PubMed - indexed for MEDLINE]

 

 

 

102: Minerva Chir  2000 Jan-Feb;55(1-2):17-23

 

[Video-thoracoscopic sympathectomy in the treatment of Raynaud's disease and

palmar hyperhidrosis]

 

[Article in Italian]

 

Trignano M, Boatto R, Mastino GP, Ferrandu T, Padula G, Loi V, Pala C.

 

Istituto di Patologia Chirurgica, Facolta di Medicina e Chirurgia, Universita

degli Studi, Sassari.

 

BACKGROUND AND AIM: Raynaud's syndrome is a clinical entity characterised by

episodic vascular spasm, digital ischemia in response to cold or emotional

stimuli and hyperhidrosis. Many patients suffering from Raynaud's syndrome are

successfully treated using medical therapy alone. Those patients who do not

respond to medical treatment undergo surgery but the indications continue to be

a source of controversy. A modern approach to thoracic sympathectomy requires a

video-assisted technique. The aim of this study is to attempt to use

mini-invasive type surgery to treat Raynaud's disease and hyperhidrosis in order

to evaluate the real efficacy of thoracic sympathectomy in a large number of

patients. The results of this method were compared for the two different

pathologies in question. METHODS: The methodology used by this study is based on

instrumental and clinical tests performed before and after surgery on treated

patients using a comparative criterion and with a minimum 5-year follow-up. The

pre- and postoperative diagnostic tests were performed by the vascular surgery

laboratory and using a C.W. Doppler and a reflected light photoplethysmograph.

Capillaroscopy and laboratory evaluations relating to secondary Raynaud's

disease were carried out by internist type structures. The patients enrolled in

the study responded to the following criteria: primary Raynaud's disease, palmar

hyperhidrosis and associated syndromes. The population came from a mixed

sociodemographic background, albeit within a strictly regional zone (Sardinia).

A total of 42 patients were studied. The surgical technique used consisted of

the ablation of thoracic ganglia from the 2nd to the 4th. RESULTS: The results

showed a resolution of symptoms in 95% of patients treated for hyperhidrosis,

whereas a 50% recidivation rate was observed in patients with Raynaud's disease

alone, although symptoms were less intense. The results for Raynaud's disease

were more disappointing, but it is important to remember that surgery is the

ultimate choice for cases with advanced lesions which do not respond to medical

treatment. Under these circumstances, the possibility of halting the evolution

of the pathology represents an auspicious achievement. CONCLUSIONS: The authors

affirm that mini-invasive surgical treatment of hyperhidrosis was resolutive

during a mean follow-up of 3 years. It therefore represents a valid method which

causes minimum esthetic damage to the patient and the greatest functional

benefit. The postoperative period is short (about 3 days) and free of major

complications. There is virtually no post-surgical pain.

 

PMID: 10832279 [PubMed - indexed for MEDLINE]

 

 

 

103: Surg Today  2000;30(12):1089-92

 

The effect of upper dorsal thoracoscopic sympathectomy on the total amount of

body perspiration.

 

Kopelman D, Assalia A, Ehrenreich M, Ben-Amnon Y, Bahous H, Hashmonai M.

 

Department of Surgery B, Rambam Medical Center and Faculty of Medicine,

Technion-Israel Institute of Technology, Haifa.

 

Thoracoscopic T2-T3 sympathectomy is the treatment of choice for primary palmar

hyperhidrosis (PPH); however, compensatory hyperhidrosis (CH) is a disturbing

sequela of this operation, the mechanism of which is poorly understood. This

study was conducted to evaluate the effect of heat stress on total body

perspiration after thoracoscopic T2-T3 sympathectomy, and determine its

correlation with CH. A total of 17 patients with PPH who underwent bilateral

T2-T3 sympathectomy were subjected to heat stress induced by a 10-min sauna bath

(ambient temperature 70 degrees C), 1 day before and 1 month after surgery. The

naked body weight was recorded before and immediately following the sauna bath,

and the patients were followed up to assess whether CH had developed and the

degree of its severity. Postoperatively, the amount of perspiration increased in

13 patients and decreased in 1. The amount of perspiration induced by the sauna

bath ranged from 60 to 480 g, with a mean value of 185.29 +/- 125.80 g, before

the operation, and from 60 to 540 g, with a mean value of 265.88 +/- 154.05 g,

after the operation (P = 0.0113). There was no correlation between the degree of

alteration in total body perspiration and the development of CH. Performing

thoracoscopic T2-T3 sympathectomy for PPH affects the total body sweating

response to heat; however, the development of CH does not correlate with this

alteration.

 

Publication Types:

Clinical Trial

 

PMID: 11193740 [PubMed - indexed for MEDLINE]

 

 

 

104: Zhonghua Wai Ke Za Zhi  2000 Jan;38(1):64-66

 

[Partial sympathectomy for treating palmar hyperhidrosis with VATS]

 

[Article in Chinese]

 

Yan Z, Zhu L, Ni K, et Al.

 

Department of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital,

Hangzhou 310014, China.

 

OBJECTIVE: To review the experience with partial sympathectomy for treating

palmar hyperhidrosis with VATS. METHODS: Between July 1995 and June 1999, 50

patients with palmar hyperhidrosis (26 males and 24 females, mean age 26.7

years) were operated. The major symptom was excessive sweating of hands, feet,

and axcillaries, sometimes in drops. Thoracoscopy was performed under general

anesthesia with a standard single-lumen endotracheal intubation with the patient

in a semi-sitting position and arms stretched at 90 degree. The approach through

two small ports on the chest wall was done using VATS. As the lung was depressed

by CO(2) insufflation in a low pressure, an excellent view of the upper

mediastinum was obtained. Ganglia T(2) through T(4), sometimes T(5) were

resected with a electrocautery probe. Bilateral procedures were completed in the

same position. RESULTS: All patients after operation became dry immediately

after sympathetic denervation with a few minor complications. Occasional side

effect was moderate compensatory sweating of the trunk. One case had recurrence

but sweating was much less than before operation. CONCLUSIONS: Because of

excellent view of the upper mediastinum for sympathetic denervation of the hand

and axcillaryies, the effect of partial sympathectomy for palmar hyperhidrosis

is satisfactory and permanent.

 

PMID: 11831992 [PubMed - as supplied by publisher]

 

 

 

105: Acta Anaesthesiol Sin  1999 Dec;37(4):221-4

 

Unilateral vocal cord paralysis following endotracheal intubation--a case

report.

 

Lu YH, Hsieh MW, Tong YH.

 

Division of Anesthesia, Taichung Hospital, Taiwan, R.O.C.

 

A 41-year-old man of ASA physical status class I was scheduled to receive the

video-assisted thoracoscopic T2 sympathectomy for hyperhidrosis palmaris. The

elective surgery was performed smoothly under general anesthesia with

endotracheal intubation. However, the patient complained of hoarseness in the

postoperative period. A stroboscopic examination showed that the left vocal cord

remained stationary in the paramedian position, signifying left vocal cord

paralysis. In the case, we believed it was most likely that endotracheal

intubation might be responsible for the unilateral vocal cord paralysis. The

possible cause was that during placement or thereafter during positioning, the

endotracheal tube was malposed or slipped upward, rendering its inflated cuff to

rest against the vocal cords. Another reason was that the cuff which was over

inflated made the vocal cords under constant pressure. Both conditions may cause

damage to the anterior branch of the recurrent laryngeal nerve. We also

discussed the general management and prophylaxis for the unilateral vocal cord

paralysis.

 

PMID: 10670122 [PubMed - indexed for MEDLINE]

 

 

 

106: Ann Thorac Surg  1999 Dec;68(6):2361-3

 

Clinical experience with video-assisted thoracic sympathectomy through the

retrosternal pulmonary junction.

 

Yamamoto H, Okada M, Kanehira A, Yamada A, Kawamura M.

 

Department of Surgery, Kobe University School of Medicine, Japan.

 

A new technique of video-assisted thoracic sympathectomy through retrosternal

pulmonary junction can be done safely using a scope guide and a flexible scope.

Bilateral thoracic sympathectomy was performed, employing a single skin

incision, in 18 patients with palmar hyperhidrosis. The advantages include

minimal neuralgia and superior cosmesis.

 

PMID: 10617045 [PubMed - indexed for MEDLINE]

 

 

 

107: Eur J Vasc Endovasc Surg  1999 Dec;18(6):543-4

 

Comment on:

 Eur J Vasc Endovasc Surg. 1999 Apr;17(4):343-6.

 

Results of thoracoscopic sympathetic trunk transection.

 

Ahn S.

 

Publication Types:

Comment

Letter

 

PMID: 10637163 [PubMed - indexed for MEDLINE]

 

 

 

108: J Pediatr Surg  1999 Dec;34(12):1839-42

 

Long-term results of 45 thoracoscopic sympathicotomies for primary hyperhidrosis

in children.

 

Imhof M, Zacherl J, Plas EG, Herbst F, Jakesz R, Fugger R.

 

University Clinic of Surgery, University of Vienna, Austria.

 

BACKGROUND/PURPOSE: Thoracoscopic sympathicotomy (TS) is successful in treatment

of excessive hyperhidrosis of the upper limb after limited follow-up

observation. The aim of the study was to assess for the first time long-term

results of TS in children. METHODS: A total of 26 children (9 boys, 17 girls)

aged 11 to 17 years with severe palmar or axillar hyperhidrosis underwent TS,

and 19 patients were treated bilaterally. A total of 19 patients were observed

after a median follow-up period of 16 years by questionnaire or clinical

examination. RESULTS: Permanent relief from palmar hyperhidrosis was given in

all examined patients. Twelve patients had compensatory and 12 patients

gustatory sweating. Postoperatively, 1 subcutaneous emphysema and 1 temporary

miosis and ptosis were noted. Eleven patients were fully satisfied with the

result. Seven patients were only partially satisfied because of compensatory or

gustatory sweating but would again undergo operation. One patient was not

satisfied because of excessive compensatory sweating. CONCLUSIONS: TS is a safe

and efficient procedure even after long-term follow-up. Severe palmar

hyperhidrosis often starts in childhood; thus, early surgical treatment can

improve social development. Compensatory and gustatory sweating are the most

frequent and enduring side effects and should be mentioned in preoperative

patient and parent information.

 

PMID: 10626868 [PubMed - indexed for MEDLINE]

 

 

 

109: Qual Life Res  1999 Dec;8(8):693-8

 

The Illness Intrusiveness Rating Scale: a measure of severity in individuals

with hyperhidrosis.

 

Cina CS, Clase CM.

 

Department of Surgery, McMaster University, Hamilton, Canada.

cinacs@fhs.mcmaster.ca

 

OBJECTIVE: We estimated the reliability and validity of the Illness

Intrusiveness Ratings Scale (IIRS) in hyperhidrosis, using an electronic mail

form of administration. METHODS: Recent contributors to an electronic mail

discussion group on hyperhidrosis responded to the IIRS, questions about

surgical history, items designed to assess severity, and demographic questions,

on two occasions four weeks apart. A variety of hypotheses regarding the

relationships between these variables were constructed a priori. RESULTS:

Sixty-eight people replied on two occasions. Internal consistency was high

(Cronbach's alpha 0.88), as was test-retest reliability (kappa 0.89). The total

IIRS score correlated with a global severity question (0.61; p < 0.001). Total

IIRS score was lower in participants who had previously had surgery for

hyperhidrosis, compared with those who had not (47 vs. 36; p = 0.02), and

changed dramatically in the direction of diminished severity in four patients

who underwent surgery during the course of the study (54 vs. 17; p = 0.01).

Weak-to-moderate correlations were observed between total score and use of

topical preparations, use of medications, number of clothing changes during a

day, and limitations in choice of wardrobe. CONCLUSIONS: The IIRS is both

reliable and valid in the assessment of patients with hyperhidrosis. A novel

form of administration does not appear to affect its properties.

 

PMID: 10855343 [PubMed - indexed for MEDLINE]

 

 

 

110: Yonsei Med J  1999 Dec;40(6):589-95

 

Thoracoscopic sympathetic surgery for hyperhidrosis.

 

Lee DY, Hong YJ, Shin HK.

 

Department of Thoracic Surgery, Yongdong Severance Hospital, Yonsei University

College of Medicine, Seoul, Korea. dylee@yumc.yonsei.ac.kr

 

Resectional surgery of sympathetic nerves has been known to be the most

effective treatment for essential hyperhidrosis and the application of

thoracoscopic electrocauterization has provided a minimally-invasive procedure

with the least morbidity and a resultant higher satisfaction rate. This paper

describes our experience on the 1,167 cases of thoracoscopic sympathetic surgery

for the treatment of essential hyperhidrosis. A total of 1,167 patients (674

males (58%) and 493 females (42%), mean age of 26.4 years with palmar (930),

craniofacial (190) or axillary (47) hyperhidrosis underwent thoracoscopic

sympathetic surgery from July 1992 to March 1999. Since the T2-4 sympathectomy,

first performed in July 1992 for a patient of palmar hyperhidrosis, the

operative methods have been altered to achieve a higher satisfaction level with

the least complication by adopting less invasive procedures. Our current

standard procedures being performed are T3 and T2 clipping for palmar and

craniofacial hyperhidrosis and T3,4 sympathicotomy for axillary hyperhidrosis,

all using a 2 mm needle thoracoscope. As the surgical procedures have been

transited to a less invasive method with limited resection using the newest

endoscopic devices, the average operation time and complications such as

Horner's syndrome and compensatory hyperhidrosis have gradually decreased and

thus the long-term satisfaction rate has been raised up to 98% for palmar

hyperhidrosis, 92% for craniofacial hyperhidrosis and 89% for axillary

hyperhidrosis. The recurrent cases (14/1167) were treated successfully with

reoperations of thoracoscopic sympathetic surgery. The optimal goal of therapy

could be achieved by complete elimination of the hyperhidrotic symptom, by

decreasing the incidence and degree of compensatory hyperhidrosis through a

selective and limited resection, and by adopting the least invasive procedures.

Sympathicotomy has provided the advantages of a limited extent of denervation

and the resultant decrease of compensatory hyperhidrosis compared to

sympathectomy. The reversible method of clipping may be an effective,

provisionary means for cases of severe, intractable compensatory sweating. For

craniofacial hyperhidrosis, T2 sympathicotomy or clipping has been proven to be

superior to the T1 sympathectomy due to the decreased occurrence of Horner's

syndrome and T3,4 sympathicotomy providing a satisfactory outcome with less

compensatory hyperhidrosis for axillary hyperhidrosis.

 

PMID: 10661037 [PubMed - indexed for MEDLINE]

 

 

 

111: Ann Vasc Surg  1999 Nov;13(6):582-5

 

Thoracoscopic cervicodorsal sympathectomy with diathermy.

 

Cartier B, Cartier P.

 

Centre Hospitalier Regional du Suroit, Valleyfield, Quebec, Canada.

 

This study reports our experience of using thoracoscopic cervicodorsal

sympathectomy with diathermy. From December 1994 to September 1998, we performed

53 thoracoscopic sympathectomies in 35 patients. There were 15 men and 20 women,

ages 18 to 61 years. Ten surgeries were performed on the right side, 7 were the

left, and 18 were bilateral. Indications for surgery were causalgia/reflex

sympathetic dystrophy in 8 patients, Raynaud's/vasculitis in 6, intractable

Raynaud's disease in 4, and hyperhydrosis in 17 (bilateral procedure). Operating

time ranged from 10 to 50 min for unilateral procedures and from 45 to 80 min

for bilateral procedures. Patients stayed in the hospital 1 to 4 days. From

favorable immediate and follow-up results we conclude that thoracoscopic

cervicodorsal sympathectomy using diathermy is feasible, safe, and effective.

 

PMID: 10541610 [PubMed - indexed for MEDLINE]

 

 

 

112: Cell Transplant  1999 Nov-Dec;8(6):583-91

 

Xenografting human T2 sympathetic ganglion from hyperhidrotic patients provides

short-term restoration of catecholaminergic functions in hemiparkinsonian

athymic rats.

 

Liu DM, Lin SZ, Wang SD, Wu MY, Wang Y.

 

Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

 

Previous studies have suggested that allografting peripheral sympathetic

ganglia, such as superior cervical ganglia, partially relieves clinical or

behavioral deficits in parkinsonian patients and animals. However, removal of

these ganglia can cause Homer's syndrome, which limits the utilization of this

approach. Hyperhidrosis, a disease of excessive sweating, is commonly seen in

young Orientals. Treatment of hyperhidrosis often involves surgical removal of

the second thoracic sympathetic ganglia (T2G), which contain catecholaminergic

neurons. The purpose of our study was to investigate behavioral responses and

tyrosine hydroxylase (TH) immunoreactivity in hemiparkinsonian rats at different

time points after transplantation of human T2G from hyperhidrotic patients.

Athymic Fisher 344 rats were injected unilaterally with 6-hydroxydopamine into

the medial forebrain bundle to destroy the nigrostriatal dopaminergic (DA)

pathway. The effectiveness of lesions was tested by measuring methamphetamine

(MA)-induced rotations. These unilaterally lesioned rats were later transplanted

with T2G or T2 fiber tract (T2F) obtained from adult hyperhidrotic patients.

Animals grafted with T2G showed a reduction in MA-induced rotation by 2 weeks;

however, rotation returned to the pregrafting levels by 3 months. Animals

receiving T2F grafts did not show any reduction of rotation over a 3-month

period. Animals were later sacrificed for TH immunostaining at different time

points. Tyrosine hydroxylase-positive [TH(+)] cell bodies and fibers were found

in the lesioned striatum 2-4 weeks after T2G grafting, suggesting the survival

of transplants. Two to 3 months after grafting, TH(+) fibers were still found in

almost all the recipients. However, TH(+) cell bodies were found in only three

of seven rats studied. Animals receiving T2F grafting did not show any TH

immunoreactivity in the lesioned striatum over the 3-month period. These data

indicate that T2G transplants from adult hyperhidrotic patients can survive and

provide transient normalization of the motor behavior in the hemiparkinsonian

athymic rats. Because of the short-term improvement in behavior after grafting,

the use of T2G in human trials should be cautious at the present time. Further

laboratory research is required.

 

PMID: 10701487 [PubMed - indexed for MEDLINE]

 

 

 

113: Hosp Med  1999 Nov;60(11):807-11

 

Current practice in thoracic sympathectomy.

 

Chaudhuri N, Birdi I, Ritchie AJ.

 

Department of Cardiothoracic Surgery, Papworth Hospital.

 

Thoracic sympathectomy has been performed for many years. With the recent

development of video assisted thoracic surgical techniques the indications for

surgery have increased, and the outcome is much better.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 10707191 [PubMed - indexed for MEDLINE]

 

 

 

114: Surg Endosc  1999 Nov;13(11):1139-42

 

Outpatient endoscopic thoracic sympathectomy using 2-mm instruments.

 

Reardon PR, Preciado A, Scarborough T, Matthews B, Marti JL.

 

Department of Surgery, Baylor College of Medicine and The Methodist Hospital,

6550 Fannin Street, Suite 2435, Houston, TX 77030, USA.

 

BACKGROUND: For a long time it has been known that sympathectomy is an effective

treatment for hyperhidrosis and other conditions. The surgical options available

until recently usually have required thoracotomy or large posterior incisions,

and physicians generally have been reluctant to recommend surgery for most

patients with "benign" disorders. Recently, thoracoscopic techniques have

allowed surgeons to offer these patients a permanent solution with minimal

surgical trauma. METHODS: In 20 patients, 30 endoscopic thoracic sympathectomies

(ETS) were performed for several indications. Nine patients had bilateral

sympathectomies. The procedures were performed on the day of admission, with the

patient under general anesthesia using double lumen endotracheal intubation and

hand temperature monitoring. Each lung was reinflated on completion of the

sympathectomy, and residual pneumothorax aspirated before closure of the

incisions. No placement of chest tubes was performed in the operating room.

RESULTS: All sympathectomies were completed thoracoscopically. There were no

major complications, and 90% of the patients were discharged within 24 hours of

admission. The average operative time was 69 min. CONCLUSIONS: Findings from

this study show that ETS is a safe and effective procedure that can be performed

routinely on an outpatient basis. The use of miniendoscopic (2-mm)

instrumentation is safe and effective in most patients and a helpful adjunct in

providing these patients with minimally traumatic surgery. Long-term results

should be evaluated on the basis of specific indications for sympathectomy.

 

PMID: 10556455 [PubMed - indexed for MEDLINE]

 

 

 

115: Surg Neurol  1999 Nov;52(5):453-7

 

Comment in:

 Surg Neurol. 2000 Jul;54(1):96-7.

 

Transthoracic endoscopic sympathectomy in the treatment of palmar

hyperhidrosis--with emphasis on perioperative management (1,360 case analyses).

 

Lin TS, Fang HY.

 

Department of Surgery, Changhua Christian Hospital, Chung Shan Medical and

Dental College, Taichung, Taiwan, ROC.

 

BACKGROUND: Primary palmar hyperhidrosis (PH) is very common, and can be

disabling. Various surgical methods for endoscopic sympathectomy have been

advocated. We present a simple and effective method of treating PH by means of

transthoracic endoscopic sympathectomy (TES). METHODS: From July 1994 to May

1998, a total of 1,360 patients with hyperhidrosis palmaris underwent TES. There

were 544 males and 816 females with a mean age of 23.1 years old (range, 5 to 60

years). All patients were placed in a half-sitting position under single-lumen

intubational anesthesia. We performed the ablation of the T2 ganglion using

either a 6- or 8-mm, 0-degree thoracoscope (Karl Storz Company, Germany)

RESULTS: In these 1,360 patients, 2,715 sympathectomies were performed. TES was

usually accomplished within 15 min. Surgical complications were minimal: six

cases of pneumothorax (0.44%), four cases of segmental collapse of lung (0.29%),

and two wound infections (0.15%). There was no surgical mortality. The mean

postoperative follow-up period was 27.8 months. A total of 1,292 patients (95%)

had highly satisfactory results, although 1,140 patients (84%) have developed

compensatory sweating of the trunk and lower limbs. The affected area was the

axillae, back, abdomen, lower limbs (16%, 82%, 52%, and 78%, respectively). The

recurrence rates of PH were 0.4% in the first year, 0.6% in the second year, and

1.1% in the third year. CONCLUSIONS: TES is a simple, safe, and effective method

of treating PH.

 

PMID: 10595764 [PubMed - indexed for MEDLINE]

 

 

 

116: J Auton Nerv Syst  1999 Oct 8;78(1):64-7

 

Left stellate stimulation increases left ventricular ejection fraction in

patients with essential palmar hyperhidrosis.

 

Wong CW, Wang CH.

 

Division of Neurosurgery, Chang Gung Memorial Hospital at Keelung, Taiwan.

c1951@netvigator.com

 

Left stellate stimulation increases cardiac contractility, heart rate, systolic

blood pressure, and QT interval in experimental animals. To see if these changes

occur in humans, we stimulated the left stellate ganglia with a monopolar

coagulation power of 5 W in 10 patients with palmar hyperhidrosis, axillar

hyperhidrosis, or both. We also stimulated the right stellate ganglia of the

other 10 patients. The mean left ventricular ejection fraction (LVEF, measured

with M-mode echocardiography), QT interval, heart rate and systolic blood

pressure of the baseline were 54.72%, 403 ms, 65/min, and 115 mmHg, whereas

those after 45 s of left stellate stimulation were 62.84%, 434 ms, 73/min, and

123 mmHg respectively. We compared these data with those of the baseline and the

two-tailed P values were 0.005 for both LVEF and QT interval, 0.052 for heart

rate, and 0.050 for systolic blood pressure respectively (Wilcoxon Matched-Pairs

Signed-Ranks Test). The corresponding P-values for those of the right stellate

stimulation were 0.721, 0.203, 0.260, and 0.326 respectively. All these suggest

that the left stellate ganglia predominate the right ones in affecting LVEF, QT

interval, heart rate and systolic blood pressure in humans, that left stellate

stimulation increases LVEF and prolongs QT interval significantly, and that left

stellate stimulation accelerates heart rate and elevates systolic blood pressure

marginally.

 

PMID: 10589825 [PubMed - indexed for MEDLINE]

 

 

 

117: Ann Thorac Surg  1999 Oct;68(4):1177-81

 

Video assistance reduces complication rate of thoracoscopic sympathicotomy for

hyperhidrosis.

 

Zacherl J, Imhof M, Huber ER, Plas EG, Herbst F, Jakesz R, Fugger R.

 

University Clinic of Surgery, Vienna General Hospital, Austria.

johannes.zacherl@akh-wien.ac.at

 

BACKGROUND: Thoracoscopic sympathicotomy has proved successful in the treatment

of palmar hyperhidrosis. However, up to 8% of patients experience Horner's

syndrome, and about 50% show compensatory sweating. This study evaluates the

role of video assistance in thoracoscopic sympathicotomy for primary

hyperhidrosis of the upper limb. METHODS: Six hundred fifty-six thoracoscopic

sympathicotomies were performed from below T1 to T4 in 369 patients. Of the

operations, 558 were done under direct view (CTS group) and 98, with video

assistance (VATS group). Follow-up was complete for 78.3% of patients after a

median observation period of 16 years. RESULTS: Dry limbs were immediately

achieved in 93% of the CTS group and 98% VATS group (p = 0.98). In the CTS

group, Horner's syndrome occurred after 2.2% of all operations and rhinitis in

8.3%. No patient in the VATS group showed any symptom of Homer's triad (p = 0.03

versus CTS group) or rhinitis (p = 0.02 versus CTS group). Compensatory sweating

was observed in 66.8% in the CTS group versus 69% in the VATS group (p = 0.73)

and gustatory sweating, in 50.4% versus 27.6%, respectively (p = 0.01).

CONCLUSIONS: In performing thoracoscopic sympathicotomy for excessive upper-limb

hyperhidrosis, we observed a significant decrease in the incidence of Horner's

syndrome, rhinitis, and gustatory sweating when the procedure was guided by

video imaging.

 

PMID: 10543476 [PubMed - indexed for MEDLINE]

 

 

 

118: Surg Laparosc Endosc Percutan Tech  1999 Oct;9(5):317-21

 

Transaxillary thoracoscopic sympathectomy experience in a hot climate:

management of the dominant hand.

 

Al Dohayan A.

 

Department of Surgery, King Khalid University Hospital, Riyadh, Saudi Arabia.

 

Primary palmar hyperhydrosis is a functionally and socially disabling problem of

unknown etiology, affecting adolescents and young adults, especially in hot

climates. Thoracoscopic sympathectomy is the most effective treatment for palmar

hyperhydrosis. Postsympathectomy rebound hyperhydrosis may limit its success,

especially in hot climates. The aim of this study is to report experience with

thoracoscopic sympathectomy in a hot climate, managing the dominant hand

(unilateral), followed by the other hand at a later date, based on the patient's

choice. One hundred twenty patients were operated on during a 3 year period. The

mean operative time was 25 minutes. The procedure was successfully completed in

169 operated limbs and was abandoned in one limb because of severe pleural

adhesions. The procedure was done for the dominant hand (unilateral) in 120

patients. Fifty patients returned for contralateral thoracoscopic sympathectomy.

There were 18 postoperative complications. Most of the patients (95%) were

discharged after an overnight stay. The early observed cure rate was high (97%).

During the mean follow-up period of 300 days, there was no recurrence of the

original symptoms, except for one patient in whom the nerve of Kuntz was found

and diathermized on the second thoracoscopy with symptomatic relief. Rebound

hyperhydrosis occurred in 40 patients (33% of the total; 21% in the unilateral

group and 42% in the bilateral group). In conclusion, it seems that

transaxillary endoscopic sympathectomy of the dominant hand is an alternative

method of treatment for patients with hyperhydrosis. Managing the dominant hand

first and giving the patient the chance to observe the severity of the rebound

hyperhydrosis may facilitate the decision for contralateral sympathectomy.

 

PMID: 10803392 [PubMed - indexed for MEDLINE]

 

 

 

119: Cardiovasc Res  1999 Aug 15;43(3):739-43

 

Sympathectomy potentiates the vasoconstrictor response to nitric oxide synthase

inhibition in humans.

 

Lepori M, Sartori C, Duplain H, Nicod P, Scherrer U.

 

Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois,

Lausanne, Switzerland.

 

OBJECTIVE: Nitric oxide exerts its cardiovascular actions at least in part by

modulation of the sympathetic vasoconstrictor tone. There is increasing evidence

that nitric oxide inhibits central neural sympathetic outflow, and preliminary

evidence suggests that it may also modulate peripheral sympathetic

vasoconstrictor tone. METHODS: To test this latter concept, in six subjects

having undergone thoracic sympathectomy for hyperhydrosis, we compared the

vascular responses to systemic L-NMMA infusion (1 mg/kg/min over 10 min) in the

innervated and the denervated limb. We also studied vascular responses to the

infusion of the non-nitric-oxide-dependent vasoconstrictor phenylephrine.

RESULTS: L-NMMA infusion evoked a roughly 3-fold larger increase in vascular

resistance in the denervated forearm than in the innervated calf. In the

denervated forearm, vascular resistance increased by 58 +/- 10 percent (mean +/-

SE), whereas in the innervated calf it increased only by 21 +/- 6 percent (P <

0.01, forearm vs. calf). This augmented vasoconstrictor response was specific

for L-NMMA, and not related to augmented non-specific vasoconstrictor

responsiveness secondary to sympathectomy, because phenylephrine infusion

increased vascular resistance similarly in the denervated forearm and the

innervated calf (by 24 +/- 7, and 29 +/- 8 percent, respectively). The augmented

vasoconstrictor response was related specifically to denervation, because in

control subjects, the vasoconstrictor responses to L-NMMA were comparable in the

forearm and the calf. CONCLUSIONS: These findings indicate that in the absence

of sympathetic innervation, the vasoconstrictor responses to nitric oxide

synthase inhibition are augmented.

 

PMID: 10690345 [PubMed - indexed for MEDLINE]

 

 

 

120: Int J Dermatol  1999 Aug;38(8):561-7

 

Comment in:

 Int J Dermatol. 2000 Feb;39(2):160.

 

Hyperhidrosis.

 

Leung AK, Chan PY, Choi MC.

 

Department of Pediatrics, University of Calgary, Alberta Children's Hospital,

and Asian Medical Centre (affiliated with the University of Calgary Medical

Clinic), Canada.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 10487442 [PubMed - indexed for MEDLINE]

 

 

 

121: J Laparoendosc Adv Surg Tech A  1999 Aug;9(4):331-4

 

Transthoracic endoscopic sympathectomy for palmar hyperhidrosis in children and

adolescents: analysis of 350 cases.

 

Lin TS.

 

General Thoracic Surgery, Changhua Christian Hospital, Chung Shan Medical and

Dental College, Taichung, ROC. Lin8065@ms14.hinet.net

 

Primary palmar hyperhidrosis (PH) often commences in childhood and adolescence

and can be a disabling condition. There are few reports regarding endoscopic

sympathectomy for PH in children and adolescents. Therefore, I present our

experience with transthoracic endoscopic sympathectomy (TES) in treating PH in

children and adolescents. From July 1994 to March 1998, a total of 350 patients

underwent TES. There were 93 males and 257 females with a mean age of 12.9 years

(range 5-17 years). All patients were placed in a half-sitting position under

single-lumen intubated anesthesia. We performed ablation of the T2 ganglion

using either a 6- or an 8-mm 0 degree thoracoscope (Karl Storz Company, Germany)

via one 0.8-cm incision just below each axilla. Among these 350 patients, 699

sympathectomies were performed. Usually, TES was accomplished within 15 minutes

(range 7-20 minutes). The surgical complications were minimal: one pneumothorax

and one segmental lung collapse. There were no surgical deaths. With a mean

postoperative follow-up period of 25 months (range 5-44 months), the result of

TES was highly satisfactory in 331 patients (94.6%), although 301 patients (86%)

developed compensatory sweating of the trunk and lower limbs, the distribution

being the axillae (12%), back (86%), abdomen (48%), or lower limbs (78%). The

recurrence rates of palmar hyperhidrosis were 0.6% in the first year, 1.1% in

the second year, and 1.7% in the third year. Transthoracic endoscopic

sympathectomy is a safe and effective method for treating PH in children and

adolescents.

 

PMID: 10488827 [PubMed - indexed for MEDLINE]

 

 

 

122: Br J Surg  1999 Jul;86(7):969-70

 

Comment on:

 Br J Surg. 1999 Jan;86(1):45-7.

 

Intermediate-term results of endoscopic transaxillary T2 sympathectomy for

primary palmar hyperhidrosis.

 

Hashmonai M, Kopelman D, Assalia A.

 

Publication Types:

Comment

Letter

 

PMID: 10475703 [PubMed - indexed for MEDLINE]

 

 

 

123: J Neurosurg  1999 Jul;91(1 Suppl):90-7

 

Comment in:

 J Neurosurg. 2000 Jan;92(1 Suppl):124.

 

Endoscopic thoracic sympathectomy.

 

Johnson JP, Obasi C, Hahn MS, Glatleider P.

 

Division of Neurosurgery, University of California, Los Angeles, USA.

johnson@surgery.medsch.ucla.edu

 

OBJECT: Thoracic sympathectomy has evolved as a treatment option for patients

with hyperhidrosis and pain disorders. In the past, surgical procedures were

highly invasive and caused significant morbidity, but the minimally invasive

thoracoscopic procedure provides detailed visualization of the sympathetic

ganglia and is associated with minimal postoperative morbidity. METHODS: The

authors performed 112 thoracoscopic sympathectomy procedures in 65 patients, and

the outcomes were equivalent to those previously established for open surgical

techniques; however, the rate of surgery-related morbidity, length of hospital

stay, and time until return to normal activity were substantially reduced.

Complications and recurrence of symptoms were comparable with those demonstrated

in previous reports. Overall patient satisfaction and willingness to undergo a

repeated operative procedure ranged from 66 to 99%. Postoperatively, higher

satisfaction rates were observed in patients with hyperhidrosis whereas in those

with pain syndromes, satisfaction rates were lower. CONCLUSIONS: Minimally

invasive thoracoscopic sympathectomy procedures are useful in treating

sympathetically mediated disorders, and the results indicate that the procedure

is associated with reduced morbidity and similar outcome when compared with

results obtained after open surgery. Hyperhidrosis is well treated, but patients

with pain syndromes have significantly poorer outcomes.

 

PMID: 10419374 [PubMed - indexed for MEDLINE]

 

 

 

124: Can J Anaesth  1999 May;46(5 Pt 1):515

 

Non-dependent axillary artery compression during needlescopic thoracic

sympathectomy.

 

Liu EH, Yih PS, Goh PM.

 

Publication Types:

Letter

 

PMID: 10349939 [PubMed - indexed for MEDLINE]

 

 

 

125: Masui  1999 May;48(5):481-6

 

[Intraoperative assessment by laser-Doppler skin blood flowmetry of the efficacy

of endoscopic thoracic sympathectomy]

 

[Article in Japanese]

 

Sano T, Fukushige T, Miyagawa Y, Yamada S, Kano T.

 

Department of Anesthesiology, Kurume University School of Medicine.

 

We have investigated whether laser-Doppler (L-D) skin blood flowmetry on the

finger could be useful for an intraoperative assessment of the efficacy of

endoscopic thoracic sympathectomy (ETS) under general anesthesia. Subjects were

5 young adults receiving ETS for palmar hyperhidrosis. ETS was performed with

the patients in the semi-sitting position under one lung ventilation. A pair of

LDF probes were placed on the palmar side of the both second fingers. Palmar

hyperhidrosis disappeared after ETS in all cases, but compensatory hyperhidrosis

developed in the back of the body and the thigh. After completion of ETS on one

side, the L-D skin blood flow increased to 267.6 +/- 211.1% on the side of ETS,

and it increased in 2 other cases and decreased on the contrary in 3 cases on

the other side. After ETS on both sides the L-D skin blood flow increased to

265.0 +/- 185.9% on the side of initial ETS and to 211.4 +/- 172.8% on the side

of subsequent ETS. The initial EST induced reflex vasoconstriction on the finger

of both sides and also on the toe. Spontaneous fluctuation and reflex

vasoconstriction of the skin blood flow were still observed, although the

periodicity of spontaneous fluctuation between the right and the left finger was

lost in some of the cases. An increase in L-D skin blood flow on the side of

ongoing ETS is useful for intraoperative assessment of ETS.

 

PMID: 10380502 [PubMed - indexed for MEDLINE]

 

 

 

126: Eur J Vasc Endovasc Surg  1999 Apr;17(4):343-6

 

Comment in:

 Eur J Vasc Endovasc Surg. 1999 Dec;18(6):543-4.

 

The results of thoracoscopic sympathetic trunk transection for palmar

hyperhidrosis and sympathetic ganglionectomy for axillary hyperhidrosis.

 

Fox AD, Hands L, Collin J.

 

University of Oxford, Nuffield Department of Surgery, John Radcliffe Hospital,

Headington, U.K.

 

OBJECTIVES: To review our total experience of thoracoscopic sympathetic trunk

transection for the treatment of palmar hyperhidrosis and second and third

thoracic sympathetic ganglionectomy for axillary hyperhidrosis. DESIGN:

Longitudinal cohort study following up consecutive patients for 0.3 to 5.5

years. SUBJECTS: Fifty-four consecutive patients undergoing thoracoscopic

sympathectomy for hyperhidrosis. METHODS: Prospective evaluation of immediate

technical success, complications, late recurrence of hyperhidrosis and patient

acceptability. RESULTS: 100% initial cure for palmar hyperhidrosis, 91% of

sympathetic ganglionectomies for axillary hyperhidrosis were technically

successful and initially curative. Compensatory sweating 44% patients, most

severe after bilateral sympathetic ganglionectomy. Complications occurred in 14%

patients, all resolving without further intervention. There were no cases of

Horner's syndrome. 13% patients reported a return of some palmar sweating. 5.4%

patients developed recurrent palmar hyperhidrosis at 6, 15 and 21 months

postoperatively. CONCLUSION: Transection of the sympathetic trunk between the

first and second thoracic sympathetic ganglia initially cures 100% of patients

treated primarily for palmar hyperhidrosis. Technically successful 2nd and 3rd

thoracic sympathetic ganglionectomy initially cures 100% of patients with

axillary hyperhidrosis. Compensatory sweating is common after bilateral

sympathectomy. Recurrent palmar hyperhidrosis occurs in 5.4% of cases, but can

be cured by a second thoracoscopic sympathectomy. Horner's syndrome is an

avoidable complication of thoracoscopic sympathectomy.

 

PMID: 10204058 [PubMed - indexed for MEDLINE]

 

 

 

127: Lakartidningen  1999 Mar 3;96(9):980-1

 

[Need for more careful alternative to sympathectomy. Complications following

surgery for palmar sweating are more common than previously thought]

 

[Article in Swedish]

 

Meyerson B.

 

PMID: 10093434 [PubMed - indexed for MEDLINE]

 

 

 

128: Internist (Berl)  1999 Mar;40(3):316

 

[Hyperhidrosis]

 

[Article in German]

 

Brehler R.

 

Zentrum fur Dermatologie, Westfalische Wilhelms-Universitat, Munster.

 

PMID: 10205758 [PubMed - indexed for MEDLINE]

 

 

 

129: J Neurosurg  1999 Mar;90(3):463-7

 

Changes in hemodynamics of the carotid and middle cerebral arteries before and

after endoscopic sympathectomy in patients with palmar hyperhidrosis:

preliminary results.

 

Jeng JS, Yip PK, Huang SJ, Kao MC.

 

Department of Neurology, National Taiwan University Hospital, Taipei.

 

OBJECT: The purpose of this study was to analyze the change in carotid and

middle cerebral artery (MCA) hemodynamics before and after endoscopic upper

thoracic sympathectomy in patients with palmar hyperhidrosis (PH). METHODS:

Sixty-eight patients with PH (35 males and 33 females) for whom the average age

was 24.5+/-10.7 years (+/- standard deviation) were recruited into this study.

These patients all underwent routine upper T-2 sympathectomy to treat their PH.

Ultrasonography studies of the carotid arteries (CAs) and MCA were obtained in

each patient before and after T-2 sympathectomy. The blood flow volume, flow

velocity, and resistivity index (RI) in the bilateral common CAs (CCAs),

internal CAs (ICAs), and external CAs (ECAs) were evaluated using duplex

ultrasonography. The systolic peak velocity, mean velocity, diastolic peak

velocity, pulsatility index, and RI of the bilateral MCAs were evaluated using

transcranial Doppler ultrasonography. Blood pressure and heart rate were also

recorded during this study. The Student paired t-test was used to analyze the

differences between studies before and after bilateral T-2 sympathectomy. There

was a significant reduction in diastolic pressure after T-2 sympathectomy (p =

0.003), but not in systolic pressure or heart rate. The vessel diameter was

increased after sympathectomy in the left CAs and right CCA. The T-2

sympathectomy led to significant elevation of blood flow volume and RI in the

left CCA, ICA, and ECA (p < 0.05). The authors found significant increases in

maximum flow velocity and RI in the left MCA (p < 0.05). CONCLUSIONS: Patients

who underwent T-2 sympathectomy demonstrated a significant increase in blood

flow volume and flow velocities of the CAs and MCA, especially on the left side.

Asymmetry of sympathetic influence on the hemodynamics of the CAs and MCA was

noted. The usefulness of sympathectomy for the treatment of ischemic

cardiovascular and cerebrovascular disease deserves further investigation.

 

PMID: 10067914 [PubMed - indexed for MEDLINE]

 

 

 

130: Kyobu Geka  1999 Mar;52(3):204-9

 

[Current appraisal of endoscopic thoracic sympathectomy: results of the national

questionnaire surgery]

 

[Article in Japanese]

 

Uchino T, Ishimaru S, Makimura S, Fukushima H.

 

Department of Surgery II, Tokyo Medical University, Japan.

 

A questionnaire survey was performed in order to investigate the current status

of endoscopic thoracic sympathectomy in Japan. Four hundred and twenty-nine

(429) university, national or public hospitals with a minimum of 400 beds were

included. A total of 248 of these hospitals responded. Among them 63 (25%)

performed this procedure. The total of the cases was 1116. The number of access

port and the technique for defunctioning the sympathetic chain were broadly

divided into three methods. These methods were equally carried out among the

departments. The clinical results were judged as satisfactory in the great

majority of patients and the frequency of complications was low. On the other

hand, the overall incidence of compensatory sweating remained relatively high

and accumulated as the number of cases increased. But the reported frequency

differed strikingly from hospital probably for lack of an objective way of

quantifying following sympathectomy. Although overall complications were

infrequent, the need for conventional thoracotomy to stop bleeding occurred in

some cases. Therefore even this simple endoscopic operation demands the utmost

surgical care, skill and experience. A few recurrences of preoperative symptoms

were seen in the follow-up suggesting that all patients must be continually

monitored after the operation.

 

PMID: 10097547 [PubMed - indexed for MEDLINE]

 

 

 

131: Lakartidningen  1999 Feb 24;96(8):930-2

 

[Complications are frequent after surgery for excessive hand sweating. Patient

should be informed about the risks]

 

[Article in Swedish]

 

Claes G, Raf L.

 

Kirurgiska kliniken, Boras lasarett.

 

PMID: 10089743 [PubMed - indexed for MEDLINE]

 

 

 

132: Eur J Cardiothorac Surg  1999 Feb;15(2):194-8

 

Influences of bilateral endoscopic transthoracic sympathicotomy on cardiac

autonomic nervous activity.

 

Tedoriya T, Sakagami S, Ueyama T, Thompson L, Hetzer R.

 

German Heart Institute Berlin, Germany. 1064601102@compuserve.com

 

OBJECTIVES: Endoscopic transthoracic sympathicotomy (ETS) is a minimal invasive

procedure of thoracic sympathetic blockage. The purpose of this study was to

evaluate cardiac autonomic nervous activity after ETS in order to confirm the

reliability and safety of ETS. METHODS: A series of electrophysiological studies

were performed before and 1 week after bilateral 2nd and 3rd thoracic

sympathicotomy in 13 patients with primary palmar hyperhydrosis. Palmar

perspiration was measured under sympathetic stress, and body surface mapping was

recorded in a supine position. In the head-up tilt test of 0, 30, 60 and 90

degrees, corrected QT interval (QTc) and T wave amplitude (Twa) were assessed.

The power spectral analysis of heart rate variability was processed to attain

power values of the low-frequency (0.04-0.15 Hz), the high-frequency (0.15-0.40

Hz) and the low/high frequency ratio. RESULTS: In all patients, the perspiration

response on the palm to sympathetic stimulation was completely inhibited after

ETS. Isointegral mapping revealed that ETS altered electroactivity on the heart.

In the head-up tilt study, R-R intervals significantly increased after the

surgery in the head-up tilt positions (P < 0.05), although there was no

significant difference in the supine position. There is no significant

difference in QTc and Twa before and after the surgery, both in the supine and

the head-up tilt positions. There was no significant difference in the LF or HF

before and after surgery, either in the supine position or the head-up tilt

positions. In the LF/HF, there was no significant difference before and after

surgery in the supine position. However, the LF/HF in the head-up tilt positions

was significantly decreased after surgery (P < 0.05). Sympathetic suppression of

ETS was recognized more obviously under the steeper head-up tilt positions.

CONCLUSIONS: The influences on the cardiac autonomic nerve system of the ETS of

upper thoracic sympathetic nerve were seen to be of a lesser degree at rest.

However, the response to sympathetic stimulation was suppressed after the

surgery.

 

PMID: 10219553 [PubMed - indexed for MEDLINE]

 

 

 

133: Acta Neurochir (Wien)  1999;141(8):855-9

 

Sensitivity, specificity and predictive value of intra-operative elevation of

hand temperature to ensure a successful T2-sympathectomy in patients with palmar

hyperhidrosis.

 

Chiou SM, Chen SC.

 

Department of Neurosurgery, Chung Shan Medical and Dental College Hospital,

Taichung, Taiwan, R.O.C.

 

To appraise the validity, intra-operative elevation of hand temperature ensuring

a successful T2-sympathectomy, we conducted a randomized, self-compared,

case-control study on 40 consecutive patients with palmar hyperhidrosis. All

patients had a postoperative follow-up of at least 18 months without recurrence.

During operation, dynamic temperature changes on their thenar eminence of both

the surgically treated and non-surgically treated hands were simultaneously

measured just before (baseline) and after completion of T2-sympathectomy, and

again 5 and 10 minutes later. An elevation of the temperature by at least 0.5

degree C from the baseline temperature was recognized as an "elevated"

temperature. The relationship between sensitivity and specificity of temperature

changes was compared using receiver operator characteristic (ROC) analysis.

Sensitivity was defined as the proportion of temperature-elevating procedures in

the group of operated hands. As a whole, post-sympathectomy elevation of hand

temperature is a useful, but not an ideal, indicator for assuring a successful

T2-sympathectomy due to its low sensitivity. At the 5-minute point, if the hand

temperature was elevated by 1 degree C, its sensitivity, specificity and

positive predictive value were 40%, 80% and 66.7%. In comparison, a 2 degrees C

elevation at the 10-minute point had a sensitivity, specificity and positive

predictive value of 30%, 90% and 75% (p < 0.05). We suggest that correct

localization of the T2 ganglion followed by adequate ablation should be the

prerequisite for use of this monitoring system.

 

PMID: 10536722 [PubMed - indexed for MEDLINE]

 

 

 

134: Acta Otolaryngol  1999;119(5):599-603

 

New objective and quantitative tests for gustatory sweating.

 

Dulguerov P, Quinodoz D, Vaezi A, Cosendai G, Piletta P, Lehmann W.

 

Division of Head and Neck Surgery, Geneva University Hospital, Switzerland.

pavel.dulguerov@hcuge.ch

 

Two newly developed tests for gustatory sweating, providing both quantitative

and topographic information, are presented. In both tests a paper stencil shaped

to fit the complex anatomy of the parotid region is used. The blotting paper

technique uses the difference in weight before and after gustatory stimulation

to measure the amount of sweating. The iodine-sublimated paper histogram (ISPH)

uses iodine sublimated office paper that changes colour when wet. The paper

stencil is than digitized and a histogram algorithm applied to measure the area

of sweating. A calibration of these tests with known and appropriate quantities

of saline is presented.

 

PMID: 10478603 [PubMed - indexed for MEDLINE]

 

 

 

135: Aust N Z J Surg  1999 Jan;69(1):60-4

 

Endoscopic thoracic sympathectomy for primary palmar hyperhidrosis: intermediate

term results.

 

Erak S, Sieunarine K, Goodman M, Lawrence-Brown M, Bell R, Chandraratna H,

Prendergast F.

 

Department of Vascular Surgery, Royal Perth Hospital, Western Australia,

Australia.

 

BACKGROUND: The authors' experience of the efficacy and safety of endoscopic

thoracic sympathectomy in the treatment of primary palmer hyperhidrosis was

examined. METHODS: A retrospective study of 71 patients (126 sympathectomies)

was undertaken. Data were retrieved by hospital records and telephone interview.

RESULTS: Follow-up was possible for 92 sympathectomies in 53 patients. Overall,

satisfactory results were achieved in 93% of patients and complications were

uncommon. Compensatory hyperhidrosis was the most common complication, which

occurred in 64% of patients; the trunk and feet were the most common sites.

Horner's syndrome occurred in five patients, although in two it was a permanent

complication. No patient expressed dissatisfaction with the procedure as a

consequence of this complication. Pneumothorax occurred in 17.5% of cases,

although the vast majority were incidental findings on a postoperative chest

X-ray, and none required drainage. With the newer techniques of access, patient

dissatisfaction with the cosmetic appearance has fallen from 27.3 to 6.4%.

Overall 90% of patients said they would have the operation again, which

represents a high level of patient satisfaction. CONCLUSIONS: Endoscopic

thoracic sympathectomy is a safe and effective technique for primary palmer

hyperhidrosis. Evolution of the technique has resulted in improvement in patient

satisfaction.

 

PMID: 9932925 [PubMed - indexed for MEDLINE]

 

 

 

136: Br J Surg  1999 Jan;86(1):139

 

Comment on:

 Br J Surg. 1998 Sep;85(9):1266.

 

Early experience with day-case transthoracic endoscopic sympathectomy.

 

Cameron A.

 

Publication Types:

Comment

Letter

 

PMID: 10027386 [PubMed - indexed for MEDLINE]

 

 

 

137: Br J Surg  1999 Jan;86(1):45-7

 

Comment in:

 Br J Surg. 1999 Jul;86(7):969-70.

 

Intermediate-term results of endoscopic transaxillary T2 sympathectomy for

primary palmar hyperhidrosis.

 

Chiou TS, Chen SC.

 

Department of Neurosurgery, Chung Shan Medical and Dental College Hospital,

Taichung, Taiwan, Republic of China.

 

BACKGROUND: This report examines the intermediate-term results of endoscopic

transaxillary T2 sympathectomy for palmar hyperhidrosis. METHODS: A

retrospective review was carried out of 91 consecutive patients, 38 men and 53

women, with a mean age of 23 years. Attention was focused on patient

satisfaction, late complications and morbidity. RESULTS: After operation, no

patient died or developed Horner's syndrome. Nine of 21 patients with

craniofacial, five of 16 with axillary and 17 of 73 with plantar hyperhidrosis

showed simultaneous improvement. Fifteen patients (16 per cent) developed

recurrent sweating, but none required reoperation. The overall mean satisfaction

rate was 78 per cent with a median 80 per cent improvement using a visual linear

analogue scale from 0 (poor) to 100 per cent (excellent). Twelve patients (13

per cent) were dissatisfied with the operative results, mainly owing to

compensatory hyperhidrosis, which occurred in 88 patients (97 per cent) within

the first year. CONCLUSION: The results of endoscopic sympathectomy deteriorate

progressively from the immediate outcome.

 

PMID: 10027358 [PubMed - indexed for MEDLINE]

 

 

 

138: Pediatr Surg Int  1999;15(7):475-8

 

Transthoracic endoscopic sympathectomy for palmar and axillary hyperhidrosis in

children and adolescents.

 

Lin TS.

 

Department of General Thoracic Surgery, Changhua Christian Hospital, Chung Shan

Medical and Dental College, Taichung, Taiwan, Republic of China.

 

Primary hyperhidrosis (PH) often starts in childhood and adolescence and can be

a troublesome condition. In Taiwan, there is a high incidence in childhood

(1.6%-2.0%) and adolescence (2.2%-2.6%). There are few reports regarding

transthoracic endoscopic sympathectomy (TES) for PH in children and adolescents.

From July 1994 to April 1998, a total of 438 patients underwent TES. There were

174 males and 264 females with a mean age of 14.2 years (range 5-17 years). All

patients were placed in a semi-sitting position under single-lumen intubation

anesthesia. We performed ablation of the T2 ganglion and any Kuntz fibers in 350

patients with palmar hyperhidrosis and a similar procedure on the T2 and T3

ganglia in 88 patients with palmar and axillary hyperhidrosis using either a 6-

or 8-mm thoracoscope via one 0.8-cm incision just below each axilla. In the 438

patients, 875 sympathectomies were performed. There was 1 technical failure due

to severe pleural adhesions. TES was usually accomplished within 15 min (range

7-20 min). All except 5 patients were discharged within 4 h after operation. The

surgical complication rate was minimal: 1 pneumothorax (0.23%) and 2 segmental

lung collapses (0.46%). There was no surgical mortality. The mean postoperative

follow-up period was 25.2 months (range 4-45 months). The result was highly

satisfactory in 408 patients (93.2%), although 377 (86%) developed compensatory

sweating of the trunk and lower limbs, the distribution affecting the back

(86%), abdomen (48%), lower limbs (78%), and soles (1.4%). The recurrence rate

of palmar hyperhidrosis was 0.6% in the 1st, 1.1% in the 2nd, and 1.7% in the

3rd year. TES is thus a safe and effective method for treating palmar and

axillary hyperhidrosis in children and adolescents.

 

PMID: 10525902 [PubMed - indexed for MEDLINE]

 

 

 

139: Surg Today  1999;29(3):209-13

 

The long-term results of upper dorsal sympathetic ganglionectomy and endoscopic

thoracic sympathectomy for palmar hyperhidrosis.

 

Lin CL, Yen CP, Howng SL.

 

Department of Neurosurgery, Kaohsiung Medical College Hospital, Taiwan.

 

To assess and compare the long-term results of upper dorsal sympathetic

ganglionectomy (UDS) and endoscopic thoracic sympathectomy (ETS), we examined 84

patients who underwent UDS and 71 patients who underwent ETS for the treatment

of palmar hyperhidrosis. The period of follow-up ranged from 37 to 228 months.

The immediate success rate was 100% in the UDS group and 98.6% in the ETS group.

Troublesome compensatory hyperhidrosis occurred in 67.8% of the UDS patients and

84.8% of the ETS patients; however, 55% of the UDS patients and 63% of the ETS

patients felt satisfied with their operation. The main reasons for

dissatisfaction were recurrence and compensatory hyperhidrosis. Interestingly,

simultaneous cure of plantar hyperhidrosis occurred in 28 (40%) of the UDS

patients and 28 (44%) of the ETS patients with concomitant plantar

hyperhidrosis. ETS required both a shorter operation time and hospital stay than

UDS. Thus, we now perform ETS as the treatment of choice because of its

excellent illumination and adequate magnification via a minimally invasive

approach. The use of ETS as the first choice of treatment for palmar

hyperhidrosis is supported not only by the immediate results, complications, and

cure of plantar hyperhidrosis, but also by the long-term results. Nevertheless,

compensatory hyperhidrosis was also a major complication after ETS.

 

Publication Types:

Clinical Trial

 

PMID: 10192729 [PubMed - indexed for MEDLINE]

 

 

 

140: Kyobu Geka  1998 Dec;51(13):1087-9

 

[Dorsal sympathectomy for palmar hyperhidrosis by the thin thoracoscope]

 

[Article in Japanese]

 

Sugiyama S, Ikeya T, Hara H, Ichiki K, Yanagi K, Doki Y, Tsuda M, Misaki T.

 

Department of Surgery, Toyama Medical and Pharmaceutical University, Japan.

 

The purpose of this study was to examine the efficiency to use by the thin

thoracoscope for the palmar hyperhidrosis. General anesthesia with double lumen

endotracheal intubation was used in all cases. A 2 mm incision made in the

anterior axillary line in the third intercostal space. Pneumothorax was obtained

by insufflation 1.5-2 L of CO2. A 2 mm endoscopic trocar was inserted through

this incision, and a 2 mm, 0-degree scope (Autosuture, USA) was introduced. A

second 2 mm trocar was inserted in the middle axillary line in the fourth

intercostal space, through which a straight endoscopic seizer was introduced.

The chain was dissected by electrocutting the white and gray rami and was

incised over the second and third ribs. To avoid puemothorax, 8 F thoracic

catheter was introduced through a guide wire which was inserted through a 2 mm

trocar. The lung was expanded, and then the thoracic catheter was removed. We

performed six sympathectomies on three female patients. All patients was

satisfied of their results. This technique used by thin thoracoscope was

cosmetic and a skin incision did not need to close too small.

 

PMID: 9866340 [PubMed - indexed for MEDLINE]

 

 

 

141: Br J Surg  1998 Nov;85(11):1504-5

 

Resympathectomy for palmar and axillary hyperhidrosis.

 

Hsu CP, Chen CY, Hsia JY, Shai SE.

 

Department of Surgery, Taichung Veterans General Hospital, Taiwan, Republic of

China.

 

BACKGROUND: The aim was to analyse patterns of failure or symptom recurrence

after primary sympathectomy for palmar or axillary hyperhidrosis, and to carry

out tactical problem-solving for resympathectomy and review the operative

findings. METHODS: Over a 2-year period, 20 patients (six men and 14 women)

underwent resympathectomy for palmar hyperhidrosis (13 patients, 20 sides) or

axillary hyperhidrosis (seven patients, ten sides). T2-3 sympathectomy for

palmar hyperhidrosis or T4-5 sympathectomy for axillary hyperhidrosis was

performed during the repeat procedure. Criteria for evaluation by means of

patient questionnaire included good (more than 80 per cent), fair (50-80 per

cent) and poor (less than 50 per cent) improvement. RESULTS: Operative findings

included inadequate sympathectomy on 19 sides, nerve regeneration on eight sides

and no evidence of previous sympathectomy on three sides. One patient had Kuntz

fibre in addition to inadequate sympathectomy. In the palmar hyperhidrosis

group, good results were obtained in all 13 patients on all 20 sides after

resympathectomy. In the axillary hyperhidrosis group, six of seven patients, or

eight of ten sides, showed good results after resympathectomy. CONCLUSION: The

main cause of primary sympathectomy failure was inadequate surgery, and

recurrence of palmar or axillary hyperhidrosis was seldom caused by nerve

regeneration. The key factor for preventing failed sympathectomy or recurrent

palmar or axillary hyperhidrosis is a first-time sympathectomy that is both

accurate and adequate. Most patients with recurrent symptoms can be cured by

resympathectomy.

 

PMID: 9823911 [PubMed - indexed for MEDLINE]

 

 

 

142: Int J Clin Pract  1998 Nov-Dec;52(8):537-8

 

Thoracoscopic (upper thoracic) sympathectomy for primary palmar hyperhidrosis in

children.

 

Rashid HI, Osman HS, McIrvine AJ.

 

Department of Surgery, Joyce Green Hospital, Dartford, Kent, UK.

 

Primary palmar hyperhidrosis is a disabling disorder that starts in childhood

and causes physical and psychological inconvenience. Conservative treatment is

not effective in severe cases. Thoracoscopic sympathectomy is the treatment of

choice. It is a safe minimally invasive procedure with good results. There are

few reports in the UK regarding surgical treatment in children. Post-operative

compensatory hyperhidrosis of the trunk and thighs occurs in up to 50% of cases.

We report on three cases involving six procedures.

 

PMID: 10622050 [PubMed - indexed for MEDLINE]

 

 

 

143: Muscle Nerve  1998 Nov;21(11):1486-92

 

Vasomotor and sudomotor function in the hand after thoracoscopic transection of

the sympathetic chain: implications for choice of therapeutic strategy.

 

Rex L, Claes G, Drott C, Pegenius G, Elam M.

 

Department of Surgery, Boras Hospital, Sweden.

 

The degree of sympatholysis achieved by thoracoscopic transection of the

sympathetic chain (sympathicotomy) was evaluated by measuring sudo- and

vasomotor function in the hands before and after surgery in 12 patients with

palmar hyperhidrosis. Our results show a marked reduction in sweat production

and a cutaneous vasodilatation which remained unchanged during the 6 months

follow-up, whereas sudo- and vasomotor reflexes normalized within this time.

Skin temperature variations did not correlate to skin perfusion changes. Since

all subjects reported dry and warm hands throughout the follow-up period, our

results indicate that recording reflex responses to sympathoexcitatory stimuli

does not adequately reflect clinical outcome of subtotal sympatholytic

procedures performed for hyperhidrosis. Monitoring of clinical outcome should

therefore include measurement of baseline sweat production and skin perfusion.

However, the normalized reflex responses highlight the incomplete sympatholysis

achieved by thoracoscopic sympathicotomy, which may be beneficial in some

pathological conditions (such as hyperhidrosis) but detrimental in others.

 

PMID: 9771674 [PubMed - indexed for MEDLINE]

 

 

 

144: Med Clin (Barc)  1998 Oct 17;111(12):479

 

Comment on:

 Med Clin (Barc). 1998 Feb 28;110(7):279.

 

[Craniofacial hyperhidrosis: a treatment with sympathectomy through

videothoracoscopy]

 

[Article in Spanish]

 

Callejas MA, Jimenez MJ, Catalan M, Baldo X.

 

Publication Types:

Comment

Letter

 

PMID: 9842536 [PubMed - indexed for MEDLINE]

 

 

 

145: Ann Thorac Cardiovasc Surg  1998 Oct;4(5):244-6

 

Results of thoracoscopic sympathectomy for 96 cases of palmar hyperhidrosis.

 

Tan V, Nam H.

 

Binh Dan Hospital, 371 Dien Bien Phu St, 3rd District, Ho Chi Minh City,

Vietnam.

 

From August 1996 to August 1997, we performed thoracoscopic sympathectomy for 96

cases of palmer hyperhidrosis. The patients' ages were from 22 to 58 years old

(mean age: 28; gender ratio: male/female: 3/2). Most of them were students,

workers or clerks. The patients were divided in two series: in 61 patients, the

sympathetic chain before the 2nd to 4th ribs was removed in the lateral approach

with a 3 hole procedure. In 35 patients, the 2nd portion of the sympathetic

chain was destroyed (by electric cauter) in the posterior approach with a 2 hole

procedure. The results were almost the same in the first series (all cases have

a fair benefit), but in the second series, some advantages may be useful for

therapy, i.e no need to turn the patients, severe compensation sweating is

minimized (from 4% ==> 0%) and the amount of holes is reduced.

 

PMID: 9828280 [PubMed - indexed for MEDLINE]

 

 

 

146: Pediatr Pulmonol  1998 Oct;26(4):262-4

 

Thoracoscopic T2-T3 sympathicolysis for essential hyperhidrosis in childhood:

effects on pulmonary function.

 

Noppen M, Dab I, D'Haese J, Meysman M, Vincken W.

 

Respiratory Division, Academic Hospital AZ-VUB, University of Brussels (V.U.B.),

Belgium. pnennm@az.vub.ac.be

 

Thoracoscopic T2-T3 sympathicolysis (TS) is a minimally invasive treatment for

patients suffering from severe, refractory essential hyperhidrosis (EH). TS has

previously been shown to be safe and efficacious in children. In order to

examine the effects of TS on respiratory function, pulmonary function tests

(PFT) were performed prior to and 6 weeks and 6 months after TS in 12 children

with EH (3 boys; mean age 12.8+/-2.5 years). Small asymptomatic decreases in

forced expiratory volume in one second (FEV1; -2%), forced expiratory flow after

expiration of 75% of vital capacity (FEF75; -9.6%), total lung capacity (TLC;

-1%), transfer factor for diffusion of carbon monoxide (T(LCO); -7.6%), and

transfer coefficient for diffusion of carbon monoxide (K(CO); -1.5%) were

observed 6 weeks after TS. These changes are comparable to those observed in

adults but did not reach statistical significance in small children. In line

with observations in adults, TLC (and T(L,CO)) returned to baseline values 6

months after TS, whereas FEV1, FEF75, and K(CO) remained at their 6-week level.

In conclusion, TS causes only small, statistically insignificant, and

asymptomatic decreases in pulmonary function in children. TS can, therefore, be

considered a safe treatment option in children suffering from severe, refractory

EH.

 

PMID: 9811076 [PubMed - indexed for MEDLINE]

 

 

 

147: Plast Reconstr Surg  1998 Oct;102(5):1629-32

 

Endoscopic transthoracic dorsal sympathectomy for the treatment of upper

extremity hyperhidrosis: a new minimally invasive approach.

 

Raposio E, Filippi F, Nordstrom RE, Santi P.

 

Department of Plastic and Reconstructive Surgery, National Institute for Cancer

Research, University of Genova, Italy.

 

Palmar and axillary hyperhidrosis are best treated surgically by endoscopic

transthoracic upper dorsal sympathectomy. At present, this methodology relies on

(at least) double trocar insertion (per side), carbon dioxide insufflation, or

both. We present a new minimally invasive endoscopic transthoracic technique,

performed by a single-entry specifically modified thoracoscope and without the

need for carbon dioxide insufflation, with the aim to reduce the drawbacks

associated with the above-mentioned, currently adopted endoscopic technique. In

our opinion, this "single-entry" technique, compared with the other reported

approaches, should theoretically minimize any damage to the intercostal

neurovascular bundle, while avoiding the complications related to carbon dioxide

insufflation.

 

PMID: 9774023 [PubMed - indexed for MEDLINE]

 

 

 

148: Surg Laparosc Endosc  1998 Oct;8(5):370-5

 

Thoracoscopic sympathectomy for hyperhidrosis: is there a learning curve?

 

Kopelman D, Hashmonai M, Ehrenreich M, Assalia A.

 

Department of Surgery B, Rambam Medical Center, and the Faculty of Medicine,

Technion, Israel Institute of Technology, Haifa.

 

The aim of this study was to evaluate the learning curve of upper dorsal

thoracoscopic sympathectomy. From June 1993 to December 1996, we performed 232

sympathectomies on 116 patients with primary palmar hyperhidrosis. The T2-T3

ganglia were resected by electrocuting and were removed for histologic

examination. The series was divided into two groups of 58 patients each, and

operations in each group occurred during a period of 21 months. Follow-up was

obtained on 111 patients for a mean of 25.06+/-12.62 months. All limbs were dry

after the operation, and hyperhidrosis did not recur. The anesthesia time was

reduced, but the operating time, the difficulty in identifying and in resecting

the ganglia, compensatory hyperhidrosis, postoperative neuralgia, and subjective

satisfaction with the procedure were similar in both groups. The learning curve

in the present study was mainly reflected by a reduction in the incidence of

Horner's syndrome.

 

PMID: 9799148 [PubMed - indexed for MEDLINE]

 

 

 

149: Br J Surg  1998 Sep;85(9):1266

 

Comment in:

 Br J Surg. 1999 Jan;86(1):139.

 

Early experience with day-case transthoracic endoscopic sympathectomy.

 

Grabham JA, Raitt D, Barrie WW.

 

The Minimal Access Surgery Trent Training Centre, Leicester General Hospital,

UK.

 

PMID: 9752873 [PubMed - indexed for MEDLINE]

 

 

 

150: Lakartidningen  1998 Aug 26;95(35):3660-2

 

[Treatment of facial blushing with endoscopic thoracal sympathicotomy. 85 per

cent of patients are satisfied, but there are adverse effects]

 

[Article in Swedish]

 

Claes G, Drott C, Dalman P, Rex L, Gothberg G, Fahlen T.

 

Kirurgiska kliniken, Boras lasarett.

 

Endoscopic transthoracic sympathicotomy, otherwise an established treatment for

palmar hyperhidrosis, was used to treat patients troubled by facial blushing,

one of the commonest symptoms of social phobia. The results were evaluated by

means of a questionnaire answered by 90 per cent (219/244) of the patients, who

rated their symptoms on a visual analogue scale (0-10) after a mean follow-up of

eight months. According to the ratings, blushing was significantly reduced from

a mean (+/- SEM) of 8.7 +/- 0.1 to 2.2 +/- 0.2 (p < 0.0001). Of the series as a

whole, 85 per cent declared themselves satisfied with the outcome.

 

PMID: 9748777 [PubMed - indexed for MEDLINE]

 

 

 

151: Surg Laparosc Endosc  1998 Aug;8(4):257-60

 

Resympathectomy for sympathetic regeneration.

 

Singh B, Moodley J, Haffejee AA, Ramdial PK, Robbs JV, Rajaruthnam P.

 

Department of Surgery, University of Natal, Durban, South Africa.

 

Explanations for recurrent sympathetic activity after an apparently successful

sympathectomy are varied and often tenuous. Among the theories given for

recurrent sympathetic activity are the development of alternate neuroanatomic

pathways, the possibility of an incomplete operation (failure to appreciate an

alternative anatomic pathway at the time of surgery, i.e., nerve of Kuntz), and

sympathetic regeneration. The latter, although long suspected, has never been

conclusively demonstrated in humans. In this report, a case of recurrent

sympathetic activity with conclusive evidence of sympathetic regeneration is

described.

 

PMID: 9703595 [PubMed - indexed for MEDLINE]

 

 

 

152: J Cardiovasc Surg (Torino)  1998 Jun;39(3):387-9

 

Computed tomography guided thoracic sympatholysis for palmar hyperhidrosis.

 

Lucas A, Rolland Y, Journeaux N, Kerdiles Y, Chevrant-Breton J, Duvauferrier R.

 

Vascular Surgical Department, Hopital Sud, C.H.R.U. de Rennes, France.

 

METHODS: Sixteen patients (mean age 26.3 years; range 18-38) with palmar

hyperhidrosis underwent 29 sympatholyses after unsuccessful medical, and in 8

ionophoresis, treatments. Sympatholysis was performed under local anesthesia

with computed tomographic guidance. After opacification of the injection site at

T3 with Iopamiron 200, phenolization was performed with 10 ml 6% phenol.

RESULTS: Good immediate results evaluated on the basis of venous dilatation, and

dryness and warmth of the skin were obtained in 23 cases (80%). There were 6

immediately unsuccessful procedures in 4 patients. At 20 months, good results,

assessed on the basis of objective criteria and subjective patient

self-evaluation were obtained in 22 cases (75% including immediate failures).

Computed tomography guided thoracic sympatholysis performed under local

anesthesia is an effective treatment for palmar hyperhidrosis. Morbidity is low

and hospital stay is short. CONCLUSIONS: Our findings suggest that thoracic

sympatholysis should be indicated as the first intention procedure when surgery

is required in patients with palmar hyperhidrosis.

 

PMID: 9678568 [PubMed - indexed for MEDLINE]

 

 

 

153: J Laparoendosc Adv Surg Tech A  1998 Jun;8(3):161-5

 

Endoscopic transthoracic sympathectomy with a fine (2-mm) thoracoscope in palmar

hyperhidrosis: a case report.

 

Okura T, Suzuki T, Suzuki S, Kitami A, Hori G.

 

Department of Thoracic and Cardiovascular Surgery, Showa University Fujigaoka

Hospital, Yokohama, Kanagawa, Japan.

 

Endoscopic transthoracic sympathectomy (ETS) is a minimally invasive method,

causing only small injuries and few complications, and requires only a short

period of hospitalization. Therefore, this method has been applied to patients

with palmar hyperhidrosis to whom the conventional transthoracic sympathectomy,

which is much more invasive, or thoracic sympathetic blockade, which often

causes complications, cannot be applied. Conventional thoracoscopes, such as a

resectoscope 8 mm in diameter for urological operations, or a thoracoscope 5 mm

in diameter, were usually used for this purpose, but they cause operative

injuries. We performed ETS using a thoracoscope 2 mm in diameter (MiniSite 2 mm

0 degrees, USSC171303). Its visual field and handling were not inferior to those

of conventional thoracoscopes, and the operative injuries were only 2 mm in

size. For the patient, a small scar of this size means virtually no scar.

 

PMID: 9681430 [PubMed - indexed for MEDLINE]

 

 

 

154: Neurosurgery  1998 Jun;42(6):1403-4

 

Comment on:

 Neurosurgery. 1997 Jul;41(1):110-3; discussion 113-5.

 

Complications in patients with palmar hyperhidrosis treated with transthoracic

endoscopic sympathectomy.

 

Heckmann M.

 

Publication Types:

Comment

Letter

 

PMID: 9632210 [PubMed - indexed for MEDLINE]

 

 

 

155: Lancet  1998 Apr 11;351(9109):1136

 

Comment on:

 Lancet. 1998 Jan 24;351(9098):231-2.

 

Compensatory hyperhidrosis after thoracic sympathectomy.

 

Collin J.

 

Publication Types:

Comment

Letter

 

PMID: 9660614 [PubMed - indexed for MEDLINE]

 

 

 

156: Lancet  1998 Apr 11;351(9109):1136

 

Comment on:

 Lancet. 1998 Jan 24;351(9098):231-2.

 

Compensatory hyperhidrosis after thoracic sympathectomy.

 

Shuster S.

 

Publication Types:

Comment

Letter

 

PMID: 9660615 [PubMed - indexed for MEDLINE]

 

 

 

157: Br J Surg  1998 Apr;85(4):570

 

Comment on:

 Br J Surg. 1997 Dec;84(12):1702-4.

 

Predicting changes in the distribution of sweating following thoracoscopic

sympathectomy.

 

Collin J.

 

Publication Types:

Comment

Letter

 

PMID: 9607547 [PubMed - indexed for MEDLINE]

 

 

 

158: Neurosurgery  1998 Apr;42(4):951-2

 

Comment on:

 Neurosurgery. 1997 Jul;41(1):110-3; discussion 113-5.

 

Complications in patients with palmar hyperhidrosis treated with transthoracic

endoscopic sympathectomy.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 9574667 [PubMed - indexed for MEDLINE]

 

 

 

159: Clin Physiol  1998 Mar;18(2):103-7

 

Finger skin blood flow in response to indirect cooling in normal subjects and in

patients before and after sympathectomy.

 

Bornmyr S, Svensson H, Soderstrom T, Sundkvist G, Wollmer P.

 

Department of Clinical Physiology, Malmo University Hospital, Sweden.

 

Finger skin blood flow was measured in 80 healthy subjects, using laser Doppler

imaging during basal vasodilatation at a local temperature of 40 degrees C. The

response to cooling of the contralateral hand at 15 degrees C was studied. A

vasoconstriction index was calculated in all subjects and a nomogram was

constructed, taking age into consideration. Compared with these normal subjects,

four patients operated on with transthoracic endoscopic sympathectomy due to

hand hyperhidrosis showed clearly attenuated responses. The results indicate

that the test can be used to assess disturbances in the sympathetic regulation

of the peripheral blood flow.

 

PMID: 9568348 [PubMed - indexed for MEDLINE]

 

 

 

160: Eur J Vasc Endovasc Surg  1998 Mar;15(3):239-43

 

Sympathetic skin response and patient satisfaction on long-term follow-up after

thoracoscopic sympathectomy for hyperhidrosis.

 

Lewis DR, Irvine CD, Smith FC, Lamont PM, Baird RN.

 

Department of Surgery, Bristol Royal Infirmary.

 

OBJECTIVES: To determine effect of sympathectomy for hyperhidrosis on

sympathetic skin response (SSR) during long-term follow-up. Patient satisfaction

was assessed and surgical complications noted. DESIGN: Prospective, Open,

Non-randomised study. MATERIALS AND METHODS: Patients who had undergone

bilateral thoracoscopic sympathectomy for hyperhidrosis underwent postoperative

assessment of SSRs. A 15 mA stimulus was applied over the median nerve

contralateral to the sympathectomy and evoked electrodermal activity was

recorded from the sympathectomised palm using a Dantec Counterpoint Mk 2.

Patient satisfaction with surgery was assessed by questionnaire and visual

analogue score (0-1.0). RESULTS: Of 26 patients, 21 were female. Mean (range)

age was 23 (9-36) years. Mean (range) follow up was 39 (4-138) months. 12% of

cases had residual or recurrent symptoms. Median (range) patient satisfaction

was 0.83 (0.06-1.0). In 7/52 palms recurrent SSRs were not detected. Repeated

measures analysis of variance found amplitude of SSR to be of low significance

with respect to time since surgery (F = 0.48; p = 0.49) and incidence of

compensatory sweating (F = 2.38; p = 0.14). CONCLUSION: Thoracoscopic

sympathectomy for hyperhidrosis is an effective procedure. Following

sympathectomy SSRs are not permanently abolished, but return of SSRs does not

correspond with symptom recurrence. As such, SSRs are a poor tool for objective

assessment of long-term outcome following sympathectomy.

 

PMID: 9587338 [PubMed - indexed for MEDLINE]

 

 

 

161: Kyobu Geka  1998 Mar;51(3):206-9

 

[Surgical technique of endoscopic transthoracic sympathicotomy: axillary

approach]

 

[Article in Japanese]

 

Ushijima T, Akemoto K, Kawakami K, Matsumoto Y, Tedoriya T, Ueyama T.

 

Department of Cardiovascular Surgery, National Hospital of Kanazawa, Japan.

 

A total of 181 endoscopic transthoracic sympathicotomy were performed at our

hospital from December, 1992 to March, 1997. After single-lumen endotracheal

intubation for general anesthesia, the patient was placed in half sitting

position. A small (1 cm) incision was made in the anterior axillary line through

the third intercostal space and an apical pneumothorax was created by

insufflation of 1.8 L of CO2 in the pleural cavity through a Surgineedle. A 24

Fr. urological transurethral electroresectoscope was introduced through the same

incision. The sympathetic chain could be observed through parietal pleura riding

on the costovertebral junctions. In palmar hyperhidrosis the second and third

thoracic sympathetic ganglia were electrocoagulated. In axillary hyperhidrosis

the forth ganglion was included. The lung was expanded by limiting expiration

and sucking CO2. The operation was repeated on the other side. Endoscopic

transthoracic sympathicotomy was an efficient, safe and low invasive surgical

procedure for the treatment of palmar, axillary hyperhidrosis, Raynaud's disease

and Buerger disease.

 

PMID: 9528226 [PubMed - indexed for MEDLINE]

 

 

 

162: Med Clin (Barc)  1998 Feb 28;110(7):279

 

Comment in:

 Med Clin (Barc). 1998 Oct 17;111(12):479.

 

[Treatment of palmar hyperhidrosis by video-thoracoscopic thoracic

sympathectomy]

 

[Article in Spanish]

 

Buitrago LJ, Molins L, Vidal G.

 

Publication Types:

Letter

 

PMID: 9562958 [PubMed - indexed for MEDLINE]

 

 

 

163: Arch Bronconeumol  1998 Feb;34(2):57-8

 

[Treatment of primary hyperhidrosis: a new indication for video thoracoscopy]

 

[Article in Spanish]

 

Callejas MA.

 

Publication Types:

Editorial

 

PMID: 9557176 [PubMed - indexed for MEDLINE]

 

 

 

164: Cardiovasc Surg  1998 Feb;6(1):94-6

 

Primary palmar hyperhidrosis presenting with unilateral symptoms: a report of

two cases and review of the literature.

 

Kopelman D, Hashmonai M, Assalia A, Bahous H.

 

Department of Surgery B, The Rambam Medical Center, and the Faculty of Medicine,

Technion-Israel Institute of Technology, Haifa, Israel.

 

Two cases of primary palmar hyperhidrosis are presented. T2-T3 sympathetic

ganglionectomy of the affected side completely alleviated perspiration of the

palms, but oversweating of the contralateral palms appeared a few weeks later. A

similar sympathetic ganglionectomy of the second side, 1 month and 1 year later,

resulted in renewed oversweating of the palm on the first operated side within 3

months of the second operation. During the same period, 127 other patients with

primary palmar hyperhidrosis underwent a bilateral upper dorsal sympathectomy,

though the condition did not recur in any of these patients. The possible

mechanism(s) of why overperspiration of the second hand developed after the

first sympathectomy in these two patients, and why it recurred in the first hand

after the second operation are examined, but remain obscure.

 

Publication Types:

Review

Review of Reported Cases

 

PMID: 9546853 [PubMed - indexed for MEDLINE]

 

 

 

165: Lancet  1998 Jan 24;351(9098):231-2

 

Comment in:

 Lancet. 1998 Apr 11;351(9109):1136.

 Lancet. 1998 Apr 11;351(9109):1136.

 

Compensatory hyperhidrosis after thoracic sympathectomy.

 

Adar R.

 

Tel Aviv University Sackler Faculty of Medicine, Tel Hashomer, Israel.

 

PMID: 9457090 [PubMed - indexed for MEDLINE]

 

 

 

166: Clin Exp Dermatol  1998 Jan;23(1):45-6

 

Essential hyperhidrosis: no evidence of abnormal personality features.

 

Kwon OS, Kim BS, Cho KH, Kwon JS, Shin MS, Youn JI, Chung JH.

 

Publication Types:

Letter

 

PMID: 9667113 [PubMed - indexed for MEDLINE]

 

 

 

167: Eur J Surg Suppl  1998;(580):33-5

 

Complications of endoscopic sympathectomy.

 

Cameron AE.

 

Department of Surgery, The Ipswich Hospital, Suffolk, UK.

 

Four cases are presented in which complications occurred during or after

thoracic endoscopic sympathectomy (TES). In one patient inappropriate TES

resulted in disabling hyperhidrosis. In one patient laceration of the subclavian

artery required major surgery. In two cases intraoperative cerebral damage

occurred. Training in TES is essential.

 

PMID: 9641383 [PubMed - indexed for MEDLINE]

 

 

 

168: Eur J Surg Suppl  1998;(580):39-42

 

Quality of life after transthoracic endoscopic sympathectomy for upper limb

hyperhidrosis.

 

Sayeed RA, Nyamekye I, Ghauri AS, Poskitt KR.

 

Department of Vascular Surgery, Cheltenham General Hospital, Gloucestershire,

UK.

 

OBJECTIVE: To assess the outcome after transthoracic endoscopic sympathectomy

(TES) for upper limb hyperhidrosis. DESIGN: Prospective cohort study. SETTING:

District general hospital. SUBJECTS: Consecutive patients undergoing TES for

upper limb hyperhidrosis over a fifteen month period. INTERVENTIONS: One-stage

bilateral TES. MAIN OUTCOME MEASURES: Change in quality of life as shown by the

Short Form-36 health assessment questionnaire. RESULTS: Sixteen patients (11

women and 5 men, median age 26 years) underwent operation without complications.

At median follow-up of 6.2 months, symptomatic improvement was found in 26 of 32

limbs treated (82%). Truncal compensatory hyperhidrosis was reported by 13

patients but was severe in only three. There were significant improvements in

social function (p = 0.01) and mental health (p = 0.025) as assessed by the

SF-36. CONCLUSION: Despite a high incidence of compensatory hyperhidrosis, TES

improved both the symptoms and overall quality of life in patients with upper

limb hyperhidrosis.

 

PMID: 9641385 [PubMed - indexed for MEDLINE]

 

 

 

169: Eur J Surg Suppl  1998;(580):13-6

 

Thoracoscopic T2-sympathetic block by clipping--a better and reversible

operation for treatment of hyperhidrosis palmaris: experience with 326 cases.

 

Lin CC, Mo LR, Lee LS, Ng SM, Hwang MH.

 

Department of Surgery, Tainan Municipal Hospital, Taiwan, ROC.

 

Although thoracoscopic sympathectomy or sympathicotomy is the best treatment for

hyperhidrosis palmaris, a new approach of clipping only without transection of

T2-sympathetic trunk is just as effective. Aside from the guaranteed cure of

hyperhidrosis, this new method has fewer complications and has the advantage of

recovery of the sympathetic tone in the hands if the procedure is reversed by

the removal of the clips. Between March 18 and September 30 of 1996, 326

patients (190 female and 136 male with a mean age of 20.5 years) underwent

thoracoscopic T2-sympathetic block by clipping to treat hyperhidrosis. Good

results and few complications were noted during follow up six months to one year

postoperatively. Five of the 326 patients, all female, had the operation

reversed because of intolerable compensatory sweating. Three recovered from the

compensatory sweating within two months and had less palmar sweating than before

their sympathetic block; the fourth achieved relief of compensatory sweating

after nine months, and the fifth reported no improvement.

 

PMID: 9641378 [PubMed - indexed for MEDLINE]

 

 

 

170: Eur J Surg Suppl  1998;(580):17-8

 

Secondary sympathetic chain reconstruction after endoscopic thoracic

sympathicotomy.

 

Telaranta T.

 

Privatix Clinic, Tampere, Finland. timo@privatix.fi

 

Thoracoscopic sympathicotomy by electrocautery is an irreversible procedure.

Thus the indications must be meticulously considered before the final decision

to operate is taken by both the surgeon and the patient. All possible side

effects should be dealt with and written informed consent required. A case of an

open nerve reconstruction of the divided sympathetic chains is presented. One

year after the reconstruction the patient reported subjective relief of the

compensatory oversweating and restoration of sweating in the face and the

armpit. Reversible methods like clipping the sympathetic chain should be

considered whenever feasible instead of the irreversible electrocoagulation of

the sympathetic chain.

 

PMID: 9641379 [PubMed - indexed for MEDLINE]

 

 

 

171: Eur J Surg Suppl  1998;(580):9-11

 

Improvements in video-endoscopic sympathicotomy for the treatment of palmar,

axillary, facial, and palmar-plantar hyperhidrosis.

 

Duarte JB, Kux P.

 

Department of Surgery, Mater Dei Hospital and Belvedere Clinic, Belo Horizonte,

Minastierais, Brazil.

 

Video-endoscopic sympathicotomy for the treatment of palmar, axillary, facial

and palmar-plantar hyperhidrosis was modified as to the type of surgical access

and the level of incision in the sympathetic chain and communicating rami,

depending on the clinical indications. Under general anaesthesia, using a single

lumen endotracheal tube, the patient is put in lateral decubitus and

pneumothorax is induced. The patient is then placed in ventral decubitus, with

the head elevated, to make two punctures in the posterior axillary line, at the

level of the 4th and 7th intercostal spaces, to introduce two ports of 5 and 10

mm in size, respectively. The sympathetic chain and the communicating rami are

viewed and severed, according to the indications, at different levels to treat

palmar, axillary, facial and palmar-plantar hyperhidrosis and combinations of

the above. The operation is performed on both sides of the thorax during the

same period of anaesthesia. One hundred-forty patients (280 procedures) have

been operated on from 1993 to 1997 using this technique. All were operated on as

outpatients. Our results are: 100% of those with facial and palmar hyperhidrosis

and 96% of those with axillar hyperhidrosis were cured, and 94% with plantar

hyperhidrosis were relieved from 50 to 100%, with the follow-up of between one

and 47 months.

 

PMID: 9641377 [PubMed - indexed for MEDLINE]

 

 

 

172: Eur J Surg Suppl  1998;(580):19-21

 

Thoracoscopic sympathectomy: the U.S. experience.

 

Krasna MJ, Demmy TL, McKenna RJ, Mack MJ.

 

Department of Surgery, University of Maryland School of Medicine, USA.

mkrasna@surgery1.ab.umd.cdu

 

OBJECTIVE: 48 patients underwent TSSYM. Charts of patients undergoing

thoracoscopy were reviewed to assess the safety and efficacy of thoracoscopic

sympathectomy (TSSYM). DESIGN: A retrospective review was undertaken at four

United States medical centers. RESULTS: TSSYM was performed for reflex

sympathetic dystrophy in 27 patients, hyperhydrosis palmaris in 15 patients, and

Raynaud's upper extremity ischemia and splanchnic pain in 2 patients each.

Anesthesia with one lung ventilation was used. 2.9 ports were used per patient

and 0.8 chest tubes were placed per patient. All patients underwent resection of

the sympathetic chain, usually with a clip along the bottom of the resected

chain. Laser, electro-ablation and electroresection were not used by any of the

surgeons in his series. The mean length of hospital stay was 1.8 days.

CONCLUSIONS: TSSYM is a safe and effective technique for treatment of a variety

of thoracic disorders.

 

Publication Types:

Multicenter Study

 

PMID: 9641380 [PubMed - indexed for MEDLINE]

 

 

 

173: Eur J Surg Suppl  1998;(580):43-6

 

Long-term results of 630 thoracoscopic sympathicotomies for primary

hyperhidrosis: the Vienna experience.

 

Zacherl J, Huber ER, Imhof M, Plas EG, Herbst F, Fugger R.

 

Department of General Surgery, University Clinic of Surgery, University of

Vienna, Vienna General Hospital, Austria. johannes.zacherl@akh-wien.ac.at

 

OBJECTIVE: To evaluate of the results of thoracoscopic sympathicotomy for upper

limb hyperhidrosis with a median observation period of more than 15 years.

DESIGN: Retrospective clinical observation study. SETTING: University-affiliated

tertiary referral centre. SUBJECTS: 630 consecutive operations in 352 patients

(median age 30.1 yrs) for primary palmar (68%), axillary (12.7%) and combined

hyperhidrosis (19.3%). INTERVENTIONS: Thoracoscopic sympathicotomy from below T1

to T4 including the fibres of Kuntz using electrocautery through single site

access. MAIN OUTCOME MEASURES: Perioperative success and complication rates (all

patients); long-term follow-up by a questionnaire and/or clinical examination

(83.3% of patients) after a median period of 16 yrs. Calculation of statistical

significance of differences between groups with c2-test. RESULTS: 67.8% of

patients were fully satisfied, 25.7% were partially satisfied and would again

agree to the operation. In 93% the procedure cured hyperhidrosis permanently.

Compensatory and gustatory sweating was observed in 67% and 47% of cases,

respectively. Overall success was significantly (p < 0.001) lower in the group

with axillary hyperhidrosis. Main complications: drainage for pneumothorax 1.3%,

Horner's syndrome in 3.8%, subcutaneous emphysema 2.1%. CONCLUSION:

Thoracoscopic sympathicotomy proved to be highly effective even after long-term

follow-up. Compensatory sweating impairs patients' satisfaction in some cases.

 

PMID: 9641386 [PubMed - indexed for MEDLINE]

 

 

 

174: Eur J Surg Suppl  1998;(580):23-6

 

The Boras experience of endoscopic thoracic sympathicotomy for palmar, axillary,

facial hyperhidrosis and facial blushing.

 

Rex LO, Drott C, Claes G, Gothberg G, Dalman P.

 

Department of Surgery, Boras Hospital, Sweden.

 

OBJECTIVE: To study the outcome of endoscopic thoracic sympaticotomy (ETS) for

palmar, axillary, facial hyperhidrosis and facial blushing. SUBJECTS: 1152

patients, 59% women and 41% men. INTERVENTION: ETS was performed by transection

of the sympathetic chain where it overlies the second and third rib. The nerve

was divided also over the fourth rib in patients with axillary hyperhidrosis.

Questionnaires were sent to all patients. MAIN OUTCOME MEASURES: The effect of

surgery was assessed by a 10 grad visual analogue scale (VAS) by the patients.

The results were divided into effect rate (the effect on the symptom) and

overall satisfaction rate, taking into account any side effects and

complications apart from the effect. RESULTS: The response rate was 90%. The

mean follow up time, effect rate and overall satisfaction rate were: 38 months

for palmar hyperhidrosis, 99.4% and 87%; 26 months for axillary hyperhidrosis,

94.5% and 68%; 31 months for facial hyperhidrosis, 97% and 76%; 8 months for

facial blushing, 96% and 85%. CONCLUSION: ETS is a very effective procedure in

palmar, axillary and facial hyperhidrosis and facial blushing. The overall

satisfaction rate is very good for palmar hyperhidrosis and facial blushing, not

equally good but acceptable for facial hyperhidrosis. The lower satisfaction

rate in patients with axillary hyperhidrosis makes this a questionable

indication for ETS.

 

PMID: 9641381 [PubMed - indexed for MEDLINE]

 

 

 

175: Eur J Surg Suppl  1998;(580):5-8

 

Thoracoscopic upper thoracic sympathectomy for primary palmar hyperhidrosis--the

combined paediatric, adolescents and adult experience.

 

Cohen Z, Levi I, Pinsk I, Mares AJ.

 

Department of Paediatric Surgery, Soroka Medical Centre, Faculty of Health

Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

 

OBJECTIVE: To present our experience, over the past 4 years, of thoracoscopic

upper thoracic sympathectomy in patients with primary palmar hyperhidrosis.

DESIGN: Retrospective study. SETTING: University hospital, Israel. SUBJECTS: 402

thoracoscopic upper thoracic sympathectomies in 223 patients over a period of 4

years. INTERVENTIONS: Thoracoscopic ablation of ganglia and severing of the

sympathetic chain at the level of T2 and T3. 142 patients underwent bilateral

simultaneous sympathectomy, 37 had bilateral non-simultaneous sympathectomy and

44 had unilateral sympathectomy. RESULTS: 220 patients (98.7%) had an uneventful

postoperative course and were discharged the following day. Three patients with

residual pneumothorax required intercostal drainage and were discharged on the

third postoperative day. 219 patients (98.2%) were completely satisfied, having

immediate and permanent relief of palmar sweating. Four patients were

dissatisfied. CONCLUSION: The thoracoscopic approach to the upper thoracic

sympathectomy is at present the procedure of choice. Early operation for severe

palmar hyperhidrosis is indicated to save a child many years of frustration and

discomfort.

 

PMID: 9641376 [PubMed - indexed for MEDLINE]

 

 

 

176: Eur J Surg Suppl  1998;(580):27-32

 

Treatment of social phobia by endoscopic thoracic sympathicotomy.

 

Telaranta T.

 

Privatix Clinic, Tampere, Finland. timo@privatix.fi

 

OBJECTIVE: To analyse the severity of various symptoms and the developmental

life history in social phobia. To estimate the value of ETS in the treatment of

chronic social phobia. DESIGN: Prospective study. SETTING: Clinic for

Psychoneurology and Surgery in Tampere, Finland. SUBJECTS: Consecutive series of

patients (n = 51). INTERVENTIONS: Endoscopic thoracic sympathicotomy. MAIN

OUTCOME MEASURES: Qualitative ideographic inquiry. Questionnaire of the symptom

severity using visual analogue scale. RESULTS: The life history included mental

and physical abuse in 61%, paternal alcoholism in 26%. Four family subtypes were

named: quarrelsome, cruel, alcoholic, and perfectionist. The pathognomonic

symptoms of social phobia: hyperhidrosis, palpitation, blushing, tremor, and

anxiety, were all highly significantly (p < 0.001) alleviated by ETS. 88% of the

patients were satisfied with the result. There were no complications.

CONCLUSION: ETS seems a promising alternative to conservative therapy for social

phobia.

 

PMID: 9641382 [PubMed - indexed for MEDLINE]

 

 

 

177: J Auton Nerv Syst  1997 Dec 11;67(3):121-4

 

The second thoracic sympathetic ganglion determines palm skin temperature in

patients with essential palmar hyperhidrosis.

 

Wong CW.

 

Division of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung Medical

College, Taipei, Taiwan, ROC. c1951@ms12.hinet.net

 

Sympathectomy of the second (T2) and third (T3) thoracic ganglion is frequently

performed for essential palmar hyperhidrosis and occasionally performed, in

addition to stellectomy, for idiopathic Raynaud's disease. The increased palm

skin temperature after the operation probably results from increased skin

perfusion. To determine whether it was possible to limit the extent of

sympathectomy for these patients, we recorded palm skin temperature after

electric stimulation of stellate, T2 and T3 ganglia, and after randomized

electrocautery of T2 and T3 ganglia in 20 patients. We analyzed the statistics

according to paired t-test with Bonferroni adjustment. We found that palm skin

temperature decreases significantly after stellate stimulation. While rising

significantly after destruction of T2 ganglion in the presence of intact T3

ganglion (P = 0.00001), palm skin temperature did not rise significantly after

T3 destruction in the presence of intact T2 (P = 0.779). Following T2 and T3

destruction, however, palm skin temperature rose despite stellate stimulation.

This suggests that T2 ganglion determines palm skin temperature while stellate

and other upper thoracic ganglia may play a minor role, that T2 sympathectomy

suffices for the treatment of essential palmar hyperhidrosis, and that

sympathectomy for Raynaud's disease might skip stellectomy.

 

PMID: 9479662 [PubMed - indexed for MEDLINE]

 

 

 

178: Anesth Analg  1997 Dec;85(6):1312-6

 

Transdiscal lumbar sympathetic block: a new technique for a chemical

sympathectomy.

 

Ohno K, Oshita S.

 

Pain Clinic, Takamatsu Red Cross Hospital, Kagawa, Japan.

 

Genitofemoral neuritis, which occurs when the neurolytic solution spreads into

the psoas muscle, is the most common complication after neurolytic lumbar

sympathetic block. We developed a transdiscal approach for neurolytic lumbar

sympathetic block to reduce the danger of genitofemoral neuritis by making a

sympathectomy without penetration of the psoas muscle, through which the

genitofemoral nerve passes. We attempted transdiscal lumbar sympathetic block in

14 patients for whom the last previous lumbar sympathetic block performed by

using the conventional paravertebral method was unsuccessful. Under fluoroscopic

guidance, the needle was inserted transdiscally at L2-3 and/or L3-4 and was

advanced until its tip pierced the anterior longitudinal ligament. Radiography

and computed tomography revealed that the injected contrast media spread along

the anterolateral surface of the vertebral column without any flow into the

psoas muscle. Alcohol was injected successfully in all patients. During the 1-mo

follow-up period, no patients had any symptom of genitofemoral neuritis.

Thirteen patients who had been suffering from lower extremity pain achieved

partial or complete pain relief. One patient with plantar hyperhidrosis achieved

persistent anhidrosis. These results suggest that the transdiscal approach can

be a technical option for neurolytic lumbar sympathetic block. Implications:

Neurolytic lumbar sympathetic block was performed with the needle advanced

through the intervertebral disc. With this technique, the risk of genitofemoral

neuritis, the most common complication after neurolytic lumbar sympathetic

block, was reduced because the needle does not penetrate the psoas muscle,

through which the genitofemoral nerve passes.

 

PMID: 9390600 [PubMed - indexed for MEDLINE]

 

 

 

179: Br J Anaesth  1997 Nov;79(5):688

 

Comment on:

 Br J Anaesth. 1997 Jul;79(1):113-9.

 

Thorascopic sympathectomy.

 

Parry-Jones AJ.

 

Publication Types:

Comment

 

Letter

 

PMID: 9422913 [PubMed - indexed for MEDLINE]

 

 

 

180: Am J Physiol  1997 Oct;273(4 Pt 2):H1696-8

 

Stimulation of left stellate ganglion prolongs Q-T interval in patients with

palmar hyperhidrosis.

 

Wong CW.

 

Division of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung Medical

College, Taipei, Taiwan, Republic of China.

 

With the advent of transthoracic video-assisted endoscopic electrocautery of the

second and the third sympathetic ganglia for the treatment of palmar

hyperhidrosis, it is possible to approach the stellate ganglia with ease. To see

whether stimulation of stellate ganglia in humans is similar to the case in

dogs, we stimulated the sympathetic ganglia in 18 palmar hyperhidrosis patients

with a coagulation power of 5 W at a frequency of three times every 2 s. We

found that left stellate stimulation prolongs the Q-T interval and increases the

heart rate, whereas right stellate stimulation affects the Q-T interval and

heart rate insignificantly, just like the case in dogs in which the left

stellate ganglion predominates the right one in determining the Q-T interval.

Left stellate stimulation after destruction of the left second and third ganglia

also prolongs the Q-T interval, suggesting that the left stellate ganglion is

more important in determining the Q-T interval.

 

PMID: 9362232 [PubMed - indexed for MEDLINE]

 

 

 

181: Ann Thorac Surg  1997 Oct;64(4):975-8

 

Thoracoscopic sympathectomy for upper limb hyperhidrosis: looking for the right

operation.

 

Gossot D, Toledo L, Fritsch S, Celerier M.

 

Department of Surgery, Saint-Louis Hospital, Paris, France.

d.gossot@chu-stlouis.fr

 

BACKGROUND: Thoracoscopic sympathectomy is the most effective treatment for

upper limb hyperhidrosis. However, this is offset by the occurrence of a high

rate of side effects, such as embarrassing compensatory sweating. Anticipating

that a technique that respects the sympathetic chain and divides only the rami

communicantes may lead to fewer side effects, we assessed the technique

described by R. Wittmoser, comparing it with conventional thoracoscopic

sympathecomy. METHODS: A total of 240 thoracoscopic sympathectomies were

performed in 124 patients suffering from upper limb hyperhidrosis. Fifty-four

patients underwent a conventional sympathectomy (group TS), 62 underwent

division of the rami communicantes with respect to the main trunk (group SS),

and 8 underwent both procedures (group TS/SS) because of accidental division of

the chain during dissection. The mean follow-up is 8 months. RESULTS: No

recurrence was observed in group TS whereas six (5%) occurred in group SS (p <

0.05). The global rate of compensatory sweating was about the same in both

groups: 72.2% in group TS and 70.9% in group SS. However, the rate of

embarrassing or disabling compensatory sweating was significantly higher in

group TS (50%) than in group SS (21%) (p < 0.001). CONCLUSIONS: Although

selective division of the rami communicantes results in a significant decrease

in the rate of disturbing side effects, it also leads to recurrences that are

usually not observed at that level in patients treated with the conventional

technique. Therefore other means of achieving the ideal operation should be

explored, that is, a technique associated with a high success rate but a minimal

number of side effects.

 

PMID: 9354512 [PubMed - indexed for MEDLINE]

 

 

 

182: J R Coll Surg Edinb  1997 Aug;42(4):287-8

 

Comment on:

 J R Coll Surg Edinb. 1996 Jun;41(3):160-3.

 

Assessment of outcome after thoracoscopic sympathectomy for hyperhidrosis in a

specialized unit.

 

Sayeed RA, Ghauri AS, Nyamekye I, Poskitt KR.

 

Publication Types:

Comment

Letter

 

PMID: 9276577 [PubMed - indexed for MEDLINE]

 

 

 

183: Pediatr Surg Int  1997 Jul 18;12(5/6):356-9

 

Laproscopic and thoracoscopic surgery in children and adolescents: A 3-year

experience

 

Cohen Z, Shinhar D, Kurzbart E, Finaly R, Mares AJ.

 

Department of Pediatric Surgery, Soroka Medical Center, Faculty of Health

Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel

 

Our initial experience over the last 3 years with laparoscopic and thoracoscopic

surgery in children and adolescents is reported. Between September 1992 and

August 1995, a total of 215 laparoscopic and thoracoscopic procedures were

performed: 32 appendectomies for acute appendicitis, 10 cholecystectomies for

symptomatic gallstones, 11 procedures for adnexal pathology, 6 laparoscopies in

children with nonpalpable testes, 3 diagnostic laparoscopies, and 153

thoracoscopic sympathectomies in children suffering from primary palmar

hyperhidrosis. The post-operative course was uneventful in all cases. In 2

children with acute appendicitis we converted to the open technique due to

technical difficulties. We are encouraged by the results of our initial

experience. There is no doubt that laparoscopic cholecystectomy, laparoscopic

surgery of adnexal pathology, and thoracoscopic sympathectomy, because of their

numerous benefits - shorter operative time, hospitalization, and convalescence

as well as less postoperative pain and improved cosmetic results - are replacing

the open techniques. We are not convinced as yet of the advantages of

laparoscopic appendectomy in children; we are presently performing both

laparoscopic and conventional techniques and studying the various parameters in

order to reach a more definite conclusion. Various other endoscopic surgical

procedures will be carefully considered in the near future.

 

PMID: 9216899 [PubMed - as supplied by publisher]

 

 

 

184: Br J Anaesth  1997 Jul;79(1):113-9

 

Comment in:

 Br J Anaesth. 1997 Nov;79(5):688.

 Br J Anaesth. 1998 Jul;81(1):100.

 

Thorascopic sympathectomy in the treatment of palmar hyperhidrosis: anaesthetic

implications.

 

Fredman B, Olsfanger D, Jedeikin R.

 

Department of Anesthesiology and Critical Care, Meir Hospital, Kfar Sava,

Israel.

 

Publication Types:

Review

Review, Academic

 

PMID: 9301398 [PubMed - indexed for MEDLINE]

 

 

 

185: Neurosurgery  1997 Jul;41(1):110-3; discussion 113-5

 

Comment in:

 Neurosurgery. 1998 Apr;42(4):951-2.

 Neurosurgery. 1998 Jun;42(6):1403-4.

 

Complications in patients with palmar hyperhidrosis treated with transthoracic

endoscopic sympathectomy.

 

Lai YT, Yang LH, Chio CC, Chen HH.

 

Department of Surgery, National Cheng-Kung University Hospital, Tainan, Taiwan,

Republic of China.

 

OBJECTIVE: To assess the complications in a group of patients with palmar

hyperhidrosis treated with transthoracic endoscopic sympathectomy. The

extraordinarily high incidence of postoperative compensatory hyperhidrosis in

our series is stressed and explained. METHODS: The retrospective study included

chart reviews and outpatient assessments. Seventy-two patients underwent T2 or

T2-T3 endoscopic sympathectomy for primary palmar hyperhidrosis. Patients'

hyperhidrosis severity, precipitating factors, postoperative complications,

surgical results, and satisfaction were assessed. Severity of palmar

hyperhidrosis and compensatory hyperhidrosis was classified by two grading

scales. RESULTS: The success rate of sympathectomy was 93%. All patients except

one suffered from compensatory sweating, which was the main cause of patients'

dissatisfaction postoperatively. Seventeen percent of the patients (12 of 72

patients) experienced new symptoms of gustatory sweating (facial sweating

associated with eating). Twenty-one patients experienced other complications,

including pneumothorax, Horner's syndrome, nasal obstruction, and intercostal

neuralgia. CONCLUSION: Transthoracic endoscopic sympathectomy is an effective

and simple modality to treat palmar hyperhidrosis. However, all patients need to

be warned of the common complications, particularly compensatory hyperhidrosis,

before surgery.

 

PMID: 9218302 [PubMed - indexed for MEDLINE]

 

 

 

186: Pediatr Surg Int  1997 Jul;12(5-6):356-9

 

Comment in:

 Pediatr Surg Int. 1998 Nov;14(1-2):151.

 

Laparoscopic and thoracoscopic surgery in children and adolescents: a 3-year

experience.

 

Cohen Z, Shinhar D, Kurzbart E, Finaly R, Mares AJ.

 

Department of Pediatric Surgery, Soroka Medical Center, Faculty of Health

Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

 

Our initial experience over the last 3 years with laparoscopic and thoracoscopic

surgery in children and adolescents is reported. Between September 1992 and

August 1995, a total of 215 laparoscopic and thoracoscopic procedures were

performed: 32 appendectomies for acute appendicitis, 10 cholecystectomies for

symptomatic gallstones, 11 procedures for adnexal pathology, 6 laparoscopies in

children with nonpalpable testes, 3 diagnostic laparoscopies, and 153

thoracoscopic sympathectomies in children suffering from primary palmar

hyperhidrosis. The post-operative course was uneventful in all cases. In 2

children with acute appendicitis we converted to the open technique due to

technical difficulties. We are encouraged by the results of our initial

experience. There is no doubt that laparoscopic cholecystectomy, laparoscopic

surgery of adnexal pathology, and thoracoscopic sympathectomy, because of their

numerous benefits - shorter operative time, hospitalization, and convalescence

as well as less postoperative pain and improved cosmetic results - are replacing

the open techniques. We are not convinced as yet of the advantages of

laparoscopic appendectomy in children; we are presently performing both

laparoscopic and conventional techniques and studying the various parameters in

order to reach a more definite conclusion. Various other endoscopic surgical

procedures will be carefully considered in the near future.

 

PMID: 9244098 [PubMed - indexed for MEDLINE]

 

 

 

187: J Auton Nerv Syst  1997 Jun 6;64(2-3):65-73

 

Altered response in cutaneous sympathetic outflow to mental and thermal stimuli

in primary palmoplantar hyperhidrosis.

 

Iwase S, Ikeda T, Kitazawa H, Hakusui S, Sugenoya J, Mano T.

 

Department of Autonomic and Behavioral Neurosciences, Nagoya University, Japan.

iwase@riem.nagoya-u.ac.jp

 

Skin sympathetic nerve activities (SSNAs) were recorded simultaneously from the

tibial and peroneal nerves by microneurography at an ambient temperature of 25

degrees C in five subjects with primary palmoplantar hyperhidrosis. The resting

of the tibial SSNA innervating the sole (glabrous skin) increased moderately

(36.5 +/- 1.5 bursts/min), while mental arithmetic provoked marked responses

(1,003.3 +/- 457.4% compared with the resting level) in the hyperhidrosis group

compared with the control normohidrosis group (n = 5, 25.3 +/ 4.2 bursts/min and

142.2 +/- 58.4%, respectively). Differentiation of the tibial SSNA into

sudomotor (innervating sweat glands) and vasoconstrictor (innervating

presphincter of skin vessels) revealed that this SSNA enhancement was

attributable to not only sudomotor but also vasoconstrictor components during

mental arithmetic. In contrast, the responses in the peroneal SSNA (innervating

the dorsum pedis, hairy skin) of the hyperhidrosis group were only slightly

changed, exhibiting no significant difference from those in the normohidrosis

group. Reflex bursts elicited by sound and electric stimulation were normal in

amplitude and latency. When the ambient temperature was elevated to 30 degrees

C, the tibial SSNAs became more enhanced than did the peroneal SSNAs. The tibial

SSNA was markedly enhanced in the hyperhidrosis group (290.0 +/- 78.5%) compared

with the normohidrosis group (78.3 +/- 25.4%). We conclude that the excessive

responses in SSNA to the plantar glabrous skin to both mental and thermal

stimuli may be responsible for the profuse sweating in subjects with primary

palmoplantar hyperhidrosis.

 

PMID: 9203126 [PubMed - indexed for MEDLINE]

 

 

 

188: J Vasc Surg  1997 May;25(5):961-2

 

Comment on:

 J Vasc Surg. 1996 Aug;24(2):194-9.

 

Regarding "Upper dorsal thoracoscopic sympathectomy for palmar hyperhidrosis:

improved intermediate-term results".

 

Deblier I, Breek JK, Herregodts P, Rutsaert R.

 

Publication Types:

Comment

Letter

 

PMID: 9152333 [PubMed - indexed for MEDLINE]

 

 

 

189: Eur J Cardiothorac Surg  1997 Apr;11(4):774-5

 

Bilateral thoracoscopy for sympathectomy in the treatment of hyperhidrosis.

 

Dumont P, Hamm A, Skrobala D, Robin P, Toumieux B.

 

Department of Thoracic Surgery, Hopital Trousseau, Tours, France.

 

Thoracoscopic sympathectomy has been established as the least invasive technique

with high success rates for treatment of palmary hyperhidrosis [1,4,5]. In our

procedure both sides are treated during the same operation. A bilateral

thoracoscopy was performed in 20 patients for incapacitating hyperhidrosis.

Immediate complications at operation were minimal. All patients reported

satisfaction with the procedure in spite of compensatory sweating. The short

hospital stay has significant financial benefits and these are increased if both

sides are treated at the same time. This procedure is more aggressive than the

single side procedure but the morbidity is not increased.

 

PMID: 9151052 [PubMed - indexed for MEDLINE]

 

 

 

190: J Neurosurg  1997 Apr;86(4):738-9

 

Comment on:

 J Neurosurg. 1996 Aug;85(2):310-5.

 

Hyperhidrosis.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 9120647 [PubMed - indexed for MEDLINE]

 

 

 

191: Minn Med  1997 Apr;80(4):50-2

 

Thoracoscopic sympathectomy for palmar hyperhidrosis. A case report.

 

Graupman PC, Rockswold GL, Blake D.

 

University of Minnesota, USA.

 

Palmar hyperhidrosis is a disabling condition that manifests itself as excessive

sweating of the hands. Although the exact cause is unknown, several medical and

surgical therapies are available to treat it. Recent developments in surgical

technique have made the less invasive thoracoscopic sympathectomy a viable

alternative to the open sympathectomy for medically refractory cases. We believe

that thoracoscopic sympathectomy is a safe and effective treatment for palmar

hyperhidrosis.

 

PMID: 9128044 [PubMed - indexed for MEDLINE]

 

 

 

192: Clin Biochem  1997 Mar;30(2):171-5

 

Effects of non-pharmacological sympathetic sudomotor denervation on sweating in

humans with essential palmar hyperhidrosis.

 

Noppen M, Sevens C, Vincken WG.

 

Respiratory Division, Academic Hospital A.Z.-V.U.B., Free University of

Brussels, Belgium.

 

OBJECTIVE: Quantitative sweat production and -ionic composition in Essential

Hyperhidrosis (EH), and the effects of T2-T3 thoracoscopic sympathicolysis (TS)

hereon, are unknown. Standardised pilocarpine iontophoresis sweat tests were

performed before and after TS in order to study these issues. DESIGN AND

METHODS: Pilocarpine iontophoretic sweat tests measuring maximal sweat

production (mg) and sweat Na+, K+ and Cl- concentrations (mMol/L) were performed

on both forearms of 10 EH patients, before and six weeks after TS, and in normal

volunteers. RESULTS: As compared to normals, preoperative maximal sweat

production was 30% higher (199.4 +/- 68.8 (SD) vs. 150.6 +/- 45.6 mg) in EH

patients; due to type II error, however, statistical significance was not

reached. Na+ and Cl- concentrations were similar, and K+ concentration was

slightly lower in EH patients. After TS, sweat production had decreased to equal

levels as in normals (149.1 +/- 52.1 mg), whereas the Na+ (from 33.6 +/- 6.9 to

51.0 +/- 6.4 mMol/L), Cl- (from 21.5 +/- 6.6 to 37.2 +/- 7.1 mMol/L) and K+

(from 7.5 +/- 1.3 to 8.6 +/- 2.2 mMol/L) concentrations had increased.

CONCLUSIONS: EH patients present 30% higher maximal sweat production at their

forearms. This increase may be due to an increased activity of the adrenergic

component of sweat gland innervation. The post-TS increase in Na+, Cl- and K+

concentrations suggests that the adrenergic component of sweat gland innervation

in itself decreases sweat ion concentrations.

 

PMID: 9127700 [PubMed - indexed for MEDLINE]

 

 

 

193: Eur J Clin Invest  1997 Mar;27(3):202-5

 

Plasma catecholamine concentrations in essential hyperhidrosis and effects of

thoracoscopic D2-D3 sympathicolysis.

 

Noppen M, Sevens C, Gerlo E, Vincken W.

 

Respiratory Division, Academic Hospital AZ-VUB, Free University of Brussels,

Belgium.

 

Essential hyperhidrosis (EH) is caused by a poorly understood overactivity of

the sympathetic fibres passing through the upper dorsal sympathetic ganglia D2

and D3. These ganglia are also in the pathway of the sympathetic innervation of

the heart and lungs. Therefore, although the predominant sympathetic

neurotransmitter at the eccrine sweat glands is acetylcholine, the plasma

concentration of noradrenaline (NA) (which is the main sympathetic

neurotransmitter at the end organs including the heart and the lungs) may be

elevated. Furthermore, as there are some indications for generalized sympathetic

overactivity in EH, the plasma concentration of adrenaline (A) may also be

elevated. Plasma levels of NA and A were therefore determined in 13 EH patients

before and after thoracoscopic D2-D3 sympathicolysis (TS). Preoperative NA and A

plasma levels were all within the normal limits used in our laboratory. After

TS, mean NA plasma levels are significantly decreased, whereas mean A are

unchanged. We conclude that sympathetic overactivity in EH is limited to the

upper dorsal sympathetic ganglia and that some of the cardiovascular and

pulmonary effects that are observed after TS may be associated with the decrease

in NA.

 

PMID: 9088855 [PubMed - indexed for MEDLINE]

 

 

 

194: Kaohsiung J Med Sci  1997 Mar;13(3):162-8

 

Transthoracic endoscopic sympathectomy for treatment of hyperhidrosis palmaris.

 

Chu D, Shi PK, Wu CM.

 

Department of Neurosurgery, Taipei Municipal Jen-Ai Hospital, Taiwan, Republic

of China.

 

The objective of this study was to determine the effectiveness of modified

transthoracic endoscopic sympathectomy (TES) being used in our institute for

treatment of hyperhidrosis palmaris (HP). One hundred and eight cases of HP were

treated using TES from June 1991 to June 1992. All underwent TES bilaterally.

Palmar temperature was monitored during the operation as an indicator of a

successful lesioning of the sympathetic trunk at the T2-level. The ages of the

patients ranged from 10 to 61 years. Fifty-one percent of these patients had a

positive family history. Seventy-three percent had onset during childhood.

Eighty-nine percent had excessive plantar sweating in addition to hyperhidrosis

palmaris. The increase in palmar temperature after lesioning the sympathetic

trunk was inversely related to the preoperative temperature of the palms (r =

0.81, p < 0.005). Our treatment resulted in improvement of palmar sweating in

all of the patients. Decrease of plantar sweating was also noted in 68% of the

patients at follow up. No neurological deficits were found. Transient

post-operative chest discomfort and compensatory hyperhidrosis (87%) were the

most common complications. TES is an effective method for treating patients with

HP, with a shorter operation time, fewer hospital days, and a better cosmetic

result, as compared with the dorsal approach for thoracic sympathectomy.

 

PMID: 9109303 [PubMed - indexed for MEDLINE]

 

 

 

195: Surg Neurol  1997 Mar;47(3):224-9; discussion 229-30

 

Transthoracic video endoscopic electrocautery of sympathetic ganglia for

hyperhidrosis palmaris: special reference to localization of the first and

second ribs.

 

Wong CW.

 

Division of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung Medical

College, Taipei, Taiwan, R.O.C.

 

BACKGROUND: The surgical technique for transthoracic endoscopic sympathectomy

varies from one to three skin incisions, room air to carbon dioxide

pneumothorax, and destruction of the second (T2), third (T3), and fourth

sympathetic ganglia to destruction of the T2 ganglion only. A knowledge of the

surgical anatomy of the apex may help the surgeon to safely use this technique.

METHODS: Forty-seven patients with palmar hyperhidrosis underwent video-assisted

endoscopic electrocautery of the T2 and T3 ganglia with the use of one-lumen

endotracheal tube for general anesthesia, one skin incision, and carbon dioxide

pneumothorax. Surgical anatomy, palm temperature, and surgical results were

analyzed. RESULTS: The first ribs of 23 patients were endoscopically visible and

most of these first ribs were not as parallel to the second ribs as the third

ribs were. The first ribs of the remaining 24 patients were palpable with a

diathermy bar. In all but three patients with dense pulmonary adhesions, the

distal end of the intrathoracic segment of the subclavian artery was seen to

pierce the pleura at the upper border of the first rib. Ninety-one palms remain

dry and 27 patients develop compensatory sweating in an average follow-up of 12

months. Excluding three patients whose sympathetic ganglia could not be

electrocauterized because of severe pulmonary adhesions, 95% of the remaining 44

patients are satisfied with the results. CONCLUSIONS: Transthoracic video

endoscopic electrocautery of the T2 and T3 ganglia for patients with palmar

hyperhidrosis may yield excellent results if the first rib can be properly

identified.

 

PMID: 9068691 [PubMed - indexed for MEDLINE]

 

 

 

196: Clin Auton Res  1997 Feb;7(1):1-4

 

Patterns of sympathetic skin response in palmar hyperhidrosis.

 

Chu EC, Chu NS.

 

Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan.

 

Sympathetic skin responses (SSRs) were studied in 44 patients with palmar

hyperhidrosis. The mean age was 19 +/- 4 years and the mean age of onset 9.1 +/-

3.6 years. Palmar SSRs were evoked by median nerve stimulation and by magnetic

stimulation of the neck. Four types of SSR were identified: normal response,

small-amplitude response, multiphasic response and absent response. Four palmar

conditions were also identified: warm-wet in 26 patients, warm-dry in seven,

cold-wet in seven, and cold-dry in four. Normal SSRs were present in about 25%

of patients and absent SSRs in another 25%. The other two types of SSR were

evenly distributed among patients, except those with cold-dry palms, who only

had absent responses. There was no apparent difference between centrally and

peripherally activated SSRs. It is concluded that skin temperature and moisture

of the palms play an important role in producing different types of SSR in

palmar hyperhidrosis.

 

Publication Types:

Clinical Trial

 

PMID: 9074822 [PubMed - indexed for MEDLINE]

 

 

 

197: Arch Phys Med Rehabil  1997 Jan;78(1):85-8

 

Intraoperative monitoring of skin temperature changes of hands before, during,

and after endoscopic thoracic sympathectomy: using infrared thermograph and

thermometer for measurement.

 

Chuang TY, Yen YS, Chiu JW, Chan RC, Chiang SC, Hsiao MP, Lee LS.

 

Department of Physical Medicine and Rehabilitation, Veterans General

Hospital-Taipei; National Yang-Ming University School of Medicine, Taiwan,

R.O.C.

 

OBJECTIVE: To investigate the roles of the second and third thoracic spinal

segments in the preganglionic sympathetic innervation of the hand, and to

compare skin temperature changes between thenar and other parts of palm before,

during, and after endoscopic thoracic sympathectomy. DESIGN: Twelve patients,

four women and eight men, with severe palmar hyperhydrosis underwent endoscopic

thoracic sympathectomy. The T3 segment was identified and dissected first,

followed by T2 segment extirpation. Skin temperature changes of the hand were

assessed by thermograph and thermometer simultaneously before, during, and after

sympathectomy. Sympathetic skin responses were undertaken 1 day preoperatively

and followed up 6 months postoperatively. SETTING: An electrophysiological

laboratory and operating room in a national medical center. SUBJECTS: Twelve

patients who sustained a profound degree of palmar hyperhydrosis. INTERVENTIONS:

Skin temperature differences of the hands were measured by infrared thermograph

and thermometer before, during, and after endoscopic thoracic sympathectomy.

MAIN OUTCOME MEASURES: Group's average temperature differences, and sympathetic

skin response (all or none response). RESULTS: The T2 spinal segment is thought

to be the main source of sympathetic outflow to the sweat glands of the hand.

The group's average temperature changes were significantly higher at the 2nd

through 5th fingers' tips than at the thenar after completion of T2 extirpation

(p < .005). CONCLUSIONS: Intraoperative monitoring of palmar skin temperature,

as judiciously measured by infrared thermograph, yields useful information about

the locations of the sympathetic segments and confirmation of their entire

ablation by endoscopic thoracic sympathectomy.

 

PMID: 9014964 [PubMed - indexed for MEDLINE]

 

 

 

198: J Palliat Care  1997 Autumn;13(3):53-4

 

Comment on:

 J Palliat Care. 1997 Spring;13(1):22-6.

 

Patients with troublesome sweating.

 

Miller M.

 

Publication Types:

Comment

Letter

 

PMID: 9354042 [PubMed - indexed for MEDLINE]

 

 

 

199: Langenbecks Arch Chir Suppl Kongressbd  1997;114:1287-9

 

[Hyperhidrosis of the upper extremity: long-term outcome of endoscopic thoracic

sympathicotomy]

 

[Article in German]

 

Zacherl J, Imhof M, Plas EG, Herbst F, Fugger R.

 

Klinische Abteilung fur Allgemeinchirurgie, Universitat Wien.

 

A total of 630 endoscopic thoracal sympathicotomies were performed for

hyperhidrosis of the upper limbs, and complications and success rates were

analyzed after a median follow-up period of 16 years (83% of patients). In all,

67.8% of patients were fully satisfied, 25.7% were partially satisfied and would

again agree to the operation, and 93% the procedure terminated hyperhidrosis

permanently. Compensatory and gustatory sweating was observed in 67% und 47% of

cases, respectively, impairing the patients satisfaction. Overall success was

significantly (p < 0.001) lower in the group with axillary hyperhidrosis.

 

PMID: 9574405 [PubMed - indexed for MEDLINE]

 

 

 

200: Neurosurgery  1997 Jan;40(1):216-7

 

Comment on:

 Neurosurgery. 1996 Apr;38(4):715-25.

 

Percutaneous radiofrequency upper thoracic sympathectomy.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 8971848 [PubMed - indexed for MEDLINE]

 

 

 

201: Stereotact Funct Neurosurg  1997;69(1-4 Pt 2):274-7

 

Video-endoscopic and mini-endoscopic sympathectomy for hyperhidrosis.

 

Pillay PK, Kumar K, Tang KK.

 

Asian Brain-Spine-Nerve Center, Singapore. neuro@pacific.net.sg

 

Video-endoscopic sympathectomy (VES) is currently the method of choice for the

minimally invasive treatment of hyperhidrosis involving the palms, armpit and

facial areas. Over a 7-year period from 1991 to 1997 our technique of performing

VES has evolved during the performance of 800 endoscopic sympathectomies from

the use of 3 ports to a single 10-mm port to finally a 3-mm port using a

mini-endoscope. In comparison to standard VES, mini-endoscopic sympathectomy is

simpler, less invasive, causes less postoperative discomfort and consistently

allows patients to return home the same day.

 

PMID: 9711766 [PubMed - indexed for MEDLINE]

 

 

 

202: Br J Surg  1996 Dec;83(12):1782

 

Abnormal suntanning following transthoracic endoscopic sympathectomy.

 

Whiteley MS, Ray-Chaudhuri SB, Galland RB.

 

Department of Surgery, Royal Berkshire Hospital, Reading, UK.

 

PMID: 9038569 [PubMed - indexed for MEDLINE]

 

 

 

203: Cardiovasc Surg  1996 Dec;4(6):788-90; discussion 790-1

 

Hyperhidrosis treated by thoracoscopic sympathicotomy.

 

Drott C, Claes G.

 

Department of Surgery, Boras Hospital, Sweden.

 

Hyperhidrosis of the palms, axillae and face has a strong negative impact on

social and professional life. The existing non-operative therapeutic options

seldom give sufficient relief and have a transient effect. A definitive cure can

be obtained by upper thoracic sympathectomy. The traditional open surgical

techniques are major procedures and few patients and surgeons have found that

the risk--benefit consideration favoured surgery. Since 1987, the authors have

divided the upper thoracic sympathetic chain on 1163 patients with a simple

endoscopic technique by using standard urological equipment. A bilateral

procedure takes less than 20 min and requires just one night in hospital. There

have been no mortality or life-threatening complications. Ten patients (< 1%)

required intercostal drainage because of haemo- or pneumothorax. Horner's

syndrome occurred in four cases. Primary failure occurred in 23 cases (< 2%) and

24 (< 2%) developed recurrent symptoms. The patients with failure and recurrence

were successfully reoperated on and only three have required a third operation.

At the end of postoperative follow-up (median 31 months) 98% of the patients

were satisfied. Endoscopic transthoracic sympathicotomy is an efficient, safe

and minimally invasive surgical method for the treatment of palmar, axillary and

facial hyperhidrosis.

 

Publication Types:

Clinical Trial

 

PMID: 9013011 [PubMed - indexed for MEDLINE]

 

 

 

204: Harefuah  1996 Nov 1;131(9):303-5, 374

 

[Thoracoscopic upper thoracic sympathectomy for primary palmar hyperhidrosis]

 

[Article in Hebrew]

 

Cohen Z, Shinhar D, Mordechai J, Mares AJ.

 

Dept. of Pediatric Surgery, Soroka Medical Center, Ben-Gurion University of the

Negev, Beer Sheba.

 

We report our initial experience, over the past 3 years, with thoracoscopic

sympathectomy for severe, primary, palmar hyperhidrosis in children and

adolescents. From 1992-1995, 179 thoracoscopic sympathectomies were performed in

61 girls and 35 boys, 5.5 to 18 years old (mean 14.8). During the first 2 years

the procedures were performed bilaterally but not simultaneously. During the

past years, 65 underwent bilateral, simultaneous sympathectomy, using a single

10 mm subaxillary port of entry. 94 (98%) had immediate and permanent relief of

palmar sweating. The immediate postoperative course was uneventful in all except

2 who had residual pneumothorax that required 24-hour intercostal drainage.

These results compare favorably with the open method and are actually better in

terms of less pain, early discharge, quicker return to normal activity and a

smaller and less conspicuous scar. We emphasize the benefits of early surgery in

children with severe, palmer hyperhidrosis, to avoid the many years of

psychological, social and physical discomfort during adolescent growth and

development.

 

PMID: 8981795 [PubMed - indexed for MEDLINE]

 

 

 

205: Arch Surg  1996 Oct;131(10):1091-4

 

Endoscopic sympathectomy treatment for craniofacial hyperhidrosis.

 

Kao MC, Chen YL, Lin JY, Hsieh CS, Tsai JC.

 

Department of Surgery, National Taiwan University Hospital, Taipei.

 

OBJECTIVE: To present endoscopic T-2 sympathectomy as a minimally invasive

therapy for craniofacial hyperhidrosis (CH). DESIGN: Follow-up study of 30

patients with CH treated by the new method in a 4-year period. The duration of

follow-up was from 8 to 44 months (mean, 15 months). SETTING: University

hospital. PATIENTS: Thirty consecutive patients with CH (18 men, 12 women)

treated by the new method. All patients were essentially in good health except

that they suffered from distressing CH to the extent that their daily activities

were often disturbed. Their ages ranged from 7 to 63 years (mean age, 42.8

years). INTERVENTION: Endoscopic sympathectomy on both sides was carried out in

a 1-stage operation for all patients. MAIN OUTCOME MEASURES: The patients were

interviewed 1 week and then 3 months after surgery and then followed up by

telephone interview about the alleviation or recurrence of CH and complications.

RESULTS: All of the treated patients obtained a satisfactory alleviation of CH.

One case was complicated by a mild and transient ptosis of the left eye. No

recurrence of CH was noticed during the follow-up period. CONCLUSIONS: This

therapeutic procedure is minimally invasive and effective. It causes minimal

discomfort and was associated with no major complications in this series. The

patients require only an overnight hospital stay and the operation scars are

small. Endoscopic sympathectomy has proven to be an effective method in treating

patients with distressing CH.

 

PMID: 8857909 [PubMed - indexed for MEDLINE]

 

 

 

206: J Cardiothorac Vasc Anesth  1996 Oct;10(6):767-71

 

Total intravenous anesthesia and high-frequency jet ventilation during

transthoracic endoscopic sympathectomy for treatment of essential hyperhidrosis

palmaris: a new approach.

 

D'Haese J, Camu F, Noppen M, Herregodts P, Claeys MA.

 

Department of Anesthesiology, University Hospital. Vrye Universiteit Brussel,

Belgium.

 

OBJECTIVE: To evaluate the effects of high-frequency jet ventilation (HFJV)

applied to both lungs on hemodynamic parameters, oxygenation, and operating

conditions during bilateral videothoracoscopic sympathectomy. DESIGN: A

prospective, unblinded study. SETTING: An ambulatory surgical unit at a

university medical center. PARTICIPANTS: 30 patients (11 men, 19 women), ASA

status 1. INTERVENTION: Bilateral videothoracoscopic sympathectomies were

performed using total intravenous anesthesia with propofol, alfentanil, and

atracurium, and the patients were ventilated with an oxygen-air mixture using

HFJV delivered to both lungs with a Hi-Lo Jet tracheal tube (Mallinckrodt).

MEASUREMENTS AND MAIN RESULTS: Mean total anesthesia time was 55 +/- 13 minutes.

Hemodynamic parameters remained stable during surgery, although ablation of the

sympathetic ganglia induced three incidences of bradycardia (10% of the

patients), which were responsive to atropine. Four patients developed oxygen

desaturation (Sa O2 < 90%) after the creation of the pneumothorax. Surgical

conditions were considered excellent by the surgeons. Concerning postoperative

complications, a temporary Horner's syndrome was observed in one patient.

Another patient had a mild residual pneumothorax on the first postoperative day

that resolved without insertion of a chest tube. CONCLUSIONS: It was concluded

that HFJV applied to both lungs is an easy and safe anesthetic technique that

provides excellent surgical conditions and causes a minor incidence of

morbidity.

 

PMID: 8910157 [PubMed - indexed for MEDLINE]

 

 

 

207: Surg Endosc  1996 Oct;10(10):1029-30

 

Simultaneous vs staged bilateral video-assisted thoracoscopic surgery.

 

Yim AP.

 

Department of Surgery, The Chinese University of Hong Kong, Prince of Wales

Hospital, Shatin, N. T., Hong Kong.

 

It is generally thought that simultaneous bilateral chest surgery carries a high

morbidity. We reviewed the results of simultaneous (under one anesthesia) vs

staged bilateral video-assisted thoracoscopic surgery (VATS) from a single

institution over a 35-month period. From September 1992 to July 1995, we

performed simultaneous bilateral VATS on 37 patients (31 males, six females, age

ranging from 15 to 55 years) with spontaneous pneumothorax (20) for bleb

resections and pleurodesis; thoracodorsal sympathectomy (12) for palmar

hyperhidrosis and vasospastic disease; and metastatic sarcomas (five) for wedge

lung resections. During the same period, nine patients with metachronous

bilateral spontaneous pneumothorax had staged procedures, as did two with

digital ischemic ulcers for sympathectomy and three with metastatic pulmonary

osteosarcomas for resection. Mean postoperative hospital stays in days for the

simultaneous groups were 3.3 for spontaneous pneumothorax, 2.1 for

sympathectomy, and 1.5 for wedge resection, compared to 2.9, 2.5, and 2.2 for

the staged groups, respectively (p > 0.05 by Mann-Whitney U tests). Likewise,

pain assessment by visual analogue scale as well as analgesic requirement showed

no significant difference between the simultaneous and the staged groups. We

conclude that simultaneous VATS is not associated with increased morbidity or

prolonged hospital stay compared to the staged counterparts and provides an

attractive alternative to the median sternotomy, bilateral posterolateral

thoracotomy, or transternal (clam-shell) thoracotomy for selected cases of

simultaneous bilateral lung surgery.

 

PMID: 8864102 [PubMed - indexed for MEDLINE]

 

 

 

208: J Auton Nerv Syst  1996 Sep 12;60(3):115-20

 

Changes in cardiocirculatory autonomic function after thoracoscopic upper dorsal

sympathicolysis for essential hyperhidrosis.

 

Noppen M, Dendale P, Hagers Y, Herregodts P, Vincken W, D'Haens J.

 

Respiratory Department of the University Hospital AZ-VUB, Free University,

Brussels, Belgium.

 

Essential hyperhidrosis (EH) is caused by an unexplained overactivity of the

sympathetic fibers which pass through the upper dorsal sympathetic ganglia D2

and D3. Since the D2 and D3 ganglia are also involved in the sympathetic cardiac

innervation, cardiocirculatory autonomic function may also be abnormal in EH. In

order to study the function of the sympathetic nervous system in EH, and to

assess the effects of thoracoscopic sympathiocolysis, cardiocirculatory

autonomic function tests were performed in 13 consecutive patients with EH,

before (baseline) and 6 weeks after the thoracoscopic intervention. Baseline

data were also compared with data obtained from 13 matched healthy volunteers:

EH patients showed an increased heart rate at rest, but only in the standing

position (94 +/- 18.5 vs 78 +/- 10.9 bpm, P < 0.01), as well as an increased

ratio of low to high frequency power of the heart rate variability in the

standing position (5.92 +/- 4.4 vs 2.8 +/- 2.5, P < 0.05). Exercise tests were

normal in every EH patient. After sympathiocolysis, heart rate at rest (sitting

on the cycloergometer) had decreased (75.4 +/- 13 vs 90.4 +/- 16.5 bpm, P <

0.05), as well as heart rate at maximal exercise (165.2 +/- 14.8 vs 180 +/- 10

bpm, P < 0.05). Exercise capacity and the cardiorespiratory responses to

exercise were, however, unchanged after sympathicolysis. Resting heart rate in

the lying (66 +/- 10 vs 76 +/- 15 bpm, P < 0.05) and standing positions (82 +/-

13.8 vs 94 +/- 18.5 bpm, P < 0.05), and the diastolic blood pressure reaction to

a handgrip test (73.6 +/- 8.6 vs 84.7 +/- 11.6 mmHg, P < 0.05) were also lowered

after sympathicolysis. In conclusion, patients with EH show an overfunctioning

of the sympathetic system which is characterised by an increased reaction to

stress (standing, exercise), whereas resting sympathetic tone is unaffected.

Thoracoscopic D2-D3 sympathicolysis corrects this hyperfunction and has a

partial beta-blocker-like activity, which results in a decrease in heart rate at

rest and during maximal exercise, and in the diastolic blood pressure response

to the handgrip test. Further studies are needed to assess the long-term

consequences of this procedure.

 

PMID: 8912261 [PubMed - indexed for MEDLINE]

 

 

 

209: Ann Acad Med Singapore  1996 Sep;25(5):673-8

 

Minimally invasive surgery: video endoscopic thoracic sympathectomy for palmar

hyperhidrosis.

 

Kao MC, Lin JY, Chen YL, Hsieh CS, Cheng LC, Huang SJ.

 

Department of Surgery, National Taiwan University Hospital, Taipei, ROC.

 

Palmar hyperhidrosis (PH) is a common disorder in Taiwan. It often causes social

embarrassment and occupational handicaps. So far, there has been no satisfactory

treatment for PH. In 1990, we first developed a minimally invasive technique:

video endoscopic sympathectomy to treat PH. The procedure has subsequently

proven to be a standard treatment for PH. In this study, a survey of 9988 cases

of PH patients from 17 hospitals in Taiwan treated by this method during the

past 5 years is presented. Although there were some variations in the model of

anaesthesia, technique and extent of sympathectomy, the postoperative results

were generally satisfactory. Both sides of sympathectomy were mostly

accomplished within half an hour in one stage. The operative scars were tiny and

concealed in the axillary region. The patients were discharged from the hospital

after an overnight stay. Complications such as pneumothorax, haemothorax (0.3%)

or Horner's syndrome (0.1%) were rare. There was no surgical mortality in this

series. The most common complication was compensatory hyperhidrosis which was

usually mild to moderate and tolerable after reassurance. The recurrence rate of

PH was approximately 1% in the first year and less than 3% during the 3 years of

follow up. Intraoperative monitoring of palmar skin temperature (PST) was

advocated to confirm an adequate sympathectomy warranting a definite result. En

bloc ablation of T2 segment invariably resulted in a rise of PST to about 2

degrees C and was considered as an adequate extent of sympathectomy for PH. The

refined technique was extended to treat young children with PH and patients with

craniofacial hyperhidrosis. The therapeutic results were generally excellent

with minimal morbidity and rare recurrence. It is concluded that video

endoscopic en bloc T2 sympathectomy is a simple, minimally invasive and

effective treatment for both adults and children with PH and also for patients

with craniofacial hyperhidrosis.

 

PMID: 8924003 [PubMed - indexed for MEDLINE]

 

 

 

210: Neurosci Behav Physiol  1996 Sep-Dec;26(5):482-8

 

State of the peripheral nervous system in patients with hypothalamic

insufficiency.

 

Filatova EG, Solov'eva AD, Kanavets EV, Rogovina EG.

 

Department of Nervous Diseases, Faculty of Advanced Postdiploma Education, I. M.

Sechenov Moscow Medical Academy.

 

An investigation was carried out by non-invasive techniques of the state of the

peripheral nervous system in patients with a constitutional-acquired form of

hypothalamic insufficiency. Ten healthy individuals were included in the control

group. The presence of subclinical parasympathetic vegetative insufficiency was

identified by cardiovascular tests. It was more marked in patients with an early

onset of the neuroendocrine disturbances and longer course of the disease. In

the opinion of the authors, this suggests the constitutional-acquired character

of the vegetative disturbances. In addition, a slowing of the speed of

conduction through the sudomotor preganglionic sympathetic fibers in the upper

and lower extremities and the predominance of these disturbances in the group of

patients with pronounced dysraphic status were identified. The latter suggests a

defect of the laying down of these peripheral vegetative fibers. This

investigation makes it possible to hypothesize that subclinical peripheral

insufficiency is one of the factors governing the occurrence of both permanent

(tachycardia, elevations of AP, hyperhidrosis) and paroxysmal vegetative

disturbances (panic attacks, migraine) in hypothalamic insufficiency.

 

Publication Types:

Clinical Trial

Controlled Clinical Trial

 

PMID: 9000222 [PubMed - indexed for MEDLINE]

 

 

 

211: Surg Endosc  1996 Sep;10(9):949

 

Chylothorax after endoscopic thoracic sympathectomy.

 

Gossot D.

 

Publication Types:

Letter

 

PMID: 8703162 [PubMed - indexed for MEDLINE]

 

 

 

212: Eur Respir J  1996 Aug;9(8):1660-4

 

Thoracoscopic sympathicolysis for essential hyperhidrosis: effects on pulmonary

function.

 

Noppen M, Vincken W.

 

Respiratory Division, Academic Hospital, AZ-VUB, University of Brussels,

Belgium.

 

Bilateral interruption of the upper dorsal sympathetic chain at the D2 and D3

level represents the only permanent cure for essential hyperhidrosis. Following

surgical sympathectomy, significant and symptomatic changes in pulmonary

function have been observed. Since functional effects of the surgical

intervention cannot be excluded, we wondered whether such alterations also

occurred after thoracoscopic sympathicolysis; these should then be attributable

to the surgical denervation itself. Pulmonary function tests (PFTs), including

spirometry and body plethysmographic measurement of lung volumes and airway

resistance and conductance, were compared before and 6 weeks after thoracoscopic

sympathicolysis in 47 patients. In order to virtually exclude any effects of

thoracoscopy on the test results PFTs were repeated 6 months after thoracoscopic

sympathicolysis in 35 patients. Essential hyperhidrosis was completely relieved

in all patients, thereby confirming the interruption of the D2-D3 sympathetic

chain. None of the patients developed respiratory symptoms after thoracoscopic

sympathicolysis. Forced expiratory volume in one second (FEV1) (-3%), forced

expiratory flow after exhaling 75% of vital capacity (FEF75) (-8%) and total

lung capacity (TLC) (-3%) were slightly but significantly reduced at six weeks

after thoracoscopic sympathicolysis; whereas airway resistance (Raw) had

increased (+12%). After correction for the small decrease in lung volume

(FEV1/forced vital capacity (FVC), specific airway resistance (sRaw), specific

airway conductance (sGaw))significant changes in "volume-dependent" PFT

parameters were no longer observed. Smoking status had no influence on the

reduction in FEF75. At 6 months after thoracoscopic sympathicolysis, TLC had

returned to preoperative values, whereas FEF75 remained decreased (-8.6%). The

decrease in airway calibre was confirmed by small but significant changes in

FEV1/FVC (-2%) and Raw (+29%). We conclude that thoracoscopic sympathicolysis in

patients with essential hyperhidrosis causes only minimal and subclinical

changes in pulmonary function secondary to a temporary small decrease in lung

volume, which in turn is probably inherent to the thoracoscopic procedure. D2-D3

sympathicolysis, in itself, is responsible only for a small and permanent

decrease in forced expiratory flow, which suggests that, at least in essential

hyperhidrosis patients, airway bronchomotor tone is influenced by sympathetic

innervation.

 

PMID: 8866591 [PubMed - indexed for MEDLINE]

 

 

 

213: J Neurosurg  1996 Aug;85(2):310-5

 

Comment in:

 J Neurosurg. 1997 Apr;86(4):738-9.

 

Orientation landmarks of endoscopic transaxillary T-2 sympathectomy for palmar

hyperhidrosis.

 

Chiou TS, Liao KK.

 

Department of Neurosurgery, Chung Shan Medical and Dental College Hospital,

Taichung, Taiwan, Republic of China.

 

The identification of the T-2 ganglion through a narrow operative viewfield is

the greatest challenge in performing endoscopic transaxillary T-2 sympathectomy,

especially for a surgeon who is unfamiliar with the technique. The authors

describe a simple anatomical method for identifying the T-2 ganglion during the

operation, based on a study of 17 adult cadavers. First, a similar clinical

procedure was performed along the anterior or middle axillary line via the

second to fourth intercostal spaces to measure the aiming angles and

intrathoracic depth needed. Second, the regional anatomical structures and their

relationship to bilateral T-2 ganglia were delineated. It was discovered that

the superior intercostal artery, a branch of the subclavian artery, was an

accessible landmark. This small vessel existed in 87.5% of the cadavers studied.

It consistently runs lateral to the parallel sympathetic chain at an average

distance of 10 mm. Most important is that it can be easily distinguished where

it runs across the inner part of the second rib. The authors emphasize that the

superior intercostal artery should be a very beneficial landmark for surgical

orientation.

 

PMID: 8755761 [PubMed - indexed for MEDLINE]

 

 

 

214: J Vasc Surg  1996 Aug;24(2):194-9

 

Comment in:

 J Vasc Surg. 1997 May;25(5):961-2.

 

Upper dorsal thoracoscopic sympathectomy for palmar hyperhidrosis: improved

intermediate-term results.

 

Kopelman D, Hashmonai M, Ehrenreich M, Bahous H, Assalia A.

 

Department of Surgery B, Rambam Medical Center, Haifa, Israel.

 

PURPOSE: The purpose of this study was to examine the immediate and mid-term

results of thoracoscopic upper dorsal (T2-T3) sympathectomy for primary palmar

hyperhidrosis. METHODS: From June 1993 to October 1994 we performed 106

sympathectomies on 53 patients with palmar hyperhidrosis. Thirty-four female

patients and 19 male patients ranging in age from 15 to 44 years, (mean 23.1

years) were studied. Both sides were operated during the same surgical

procedure. The T2-T3 ganglia were resected by electrocuting with a hook and were

removed for histologic examination. Follow-up for a mean of 19.25 months was

obtained on 52 patients (104 operated limbs). RESULTS: All limbs were completely

dry at the end of the procedure, and hyperhidrosis did not recur during the

whole follow-up period. Short-term postoperative complications (mainly

atelectasis, pneumonia, pneumothorax, and hemothorax) occurred in six (11.3%)

patients. Long-term sequelae were observed in 43 (81.1%) patients and included

Horner's syndrome (9 patients, 17.3%, one side only in each patient), neuralgia

(7 patients, 13.5%), and compensatory hyperhidrosis (35 patients, 67.3%). These

sequelae were not permanent in all cases, and the degree of severity was

variable. Six (11.5%) patients, three of whom regretted being operated, were

dissatisfied with their results: one because of Horner's syndrome, one because

of persisting neuralgia, and four because of compensatory sweating. CONCLUSIONS:

Despite the large number of postoperative long-term sequelae, 88.5% of patients

expressed subjective satisfaction from the procedure. Obtaining 100% of dry

hands on mid-term follow-up makes this approach rewarding.

 

PMID: 8752028 [PubMed - indexed for MEDLINE]

 

 

 

215: Surg Laparosc Endosc  1996 Aug;6(4):258-61

 

Experience in thoracoscopic sympathectomy for hyperhidrosis with concomitant

pleural adhesion.

 

Lin CC, Mo LR.

 

Department of Surgery, Tainan Municipal Hospital, Taiwan.

 

Thoracoscopic (transthoracic endoscopic) sympathectomy, known worldwide as the

best method for treatment of hyperhidrosis, is regarded as having two major

contraindications: pleural adhesion and coagulopathy. We embarked on this study

to prove that it is possible and highly feasible to do thoracoscopic

sympathectomy, even in the presence of severe pleural adhesion, as long as the

surgeon knows anatomy and is well-trained in performing this procedure. From

October 1, 1989, through December 31, 1992, we treated 719 cases of

hyperhidrosis palmaris (325 male and 394 female patients), by the thoracoscopic

method at Tainan Municipal Hospital. Among them, 24 cases (3.5%), 19 male and 5

female patients, had concomitant pleural adhesions. The causes of pleural

adhesion were pulmonary tuberculosis, chronic bronchitis, previous operations

for hyperhidrosis, and a few with uncertain origins. Except for the first

encountered case of hyperhidrosis with pleural adhesion, which was treated by

mini-thoracotomy after failure of a thoracoscopic approach through the right

thoracic cavity, the remainder of the 23 cases were treated successfully by the

thoracoscopic method. In cases with bilateral pleural adhesions, the right

thoracic cavity was more frequently involved and more severely. The incidence of

pleural adhesion in hyperhidrosis is 3.5% in our series; all, except the first

case, were treated thoracoscopically. Coagulopathy is for us, therefore, the

only remaining contraindication of thoracoscopic sympathectomy.

 

PMID: 8840445 [PubMed - indexed for MEDLINE]

 

 

 

216: J Auton Nerv Syst  1996 Jul 5;59(3):98-102

 

Contralateral temperature changes of the finger surface during video endoscopic

sympathectomy for palmar hyperhidrosis.

 

Wu JJ, Hsu CC, Liao SY, Liu JC, Shih CJ.

 

Department of Surgery, Far Eastern Memorial Hospital, Taipei, Taiwan, ROC.

 

One hundred and eight consecutive patients with primary palmar hyperhidrosis

were surgically managed by coagulation of bilateral T2 sympathetic ganglia using

video thoracoscopic techniques. Patients were divided into two groups. In the

first group (N = 46), finger surface temperature of the ipsilateral index finger

was recorded before and after T2 ganglionectomy. The average increase of

post-operative temperature was 2.74 +/- 0.27 degrees C (mean +/- SE) on the

right side and 2.67 +/- 0.33 degrees C on the left (P < 0.05). The significant

rise of temperature resulting from sympatholytic vasodilatation was only noted

in cases of exact ablation of the T2 ganglion. In the second group (N = 62),

surface temperatures of both index fingers were monitored and recorded

simultaneously. These patients were arbitrarily subdivided into Group 2-A (N =

29) when right side ganglionectomy was performed first and Group 2-B (N = 33)

when left side ganglionectomy was done initially. After the first ganglionectomy

was completed, an ipsilateral increase with a contralateral decrease of

temperature was observed; the average increase of temperature was 1.92 +/- 0.35

degrees C and 2.19 +/- 0.30 degrees C, and the average decrease was 1.50 +/-

0.51 degrees C and 1.67 +/- 0.39 degrees C for Group 2-A and 2-B respectively (P

< 0.05). The authors postulate that a cross-inhibitory effect by the

post-ganglionic neurons innervating blood vessels of the upper extremities may

exists in humans and this effect is released after ganglionectomy, resulting in

contralateral vasoconstriction and decrease of finger surface temperature.

 

PMID: 8832515 [PubMed - indexed for MEDLINE]

 

 

 

217: Surg Endosc  1996 Jul;10(7):721-3

 

Advantages of limited thoracoscopic sympathectomy.

 

Bonjer HJ, Hamming JF, du Bois NAJJ, van Urk H.

 

Department of Surgery, University Hospital Dijkzigt, Dr. Molewaterplein 40, 3015

GD Rotterdam, The Netherlands.

 

BACKGROUND: Thoracoscopic resection of the first through the fourth thoracic

sympathetic ganglion for palmary and axillary hyperhidrosis and Raynaud's

syndrome is associated with a high initial success rate. However, the reported

incidence of compensatory hyperhidrosis of the trunk and legs and Horner's

syndrome are high. This study assesses the results of thoracoscopic

sympathectomy limited to transection of the interganglionic trunk or resection

of one or two thoracic ganglia. METHODS: Twenty-eight thoracoscopic

sympathectomies were done for dystrophy of the hand (n = 9), palmar and axillary

hyperhidrosis (n = 6), and Raynaud's syndrome (n = 4). The extent of

sympathectomy varied from interganglionic division between the second and third

ganglion (n = 12), to resection of the third ganglion (n = 12), to resection of

the second and third ganglion (n = 4). RESULTS: Sympathectomy resulted initially

in relief of symptoms in all cases. Horner's syndrome did not occur.

CONCLUSIONS: After a median follow-up of 11 months, two of nine patients with

dystrophy judged the result of operation as good. All patients with

hyperhidrosis and Raynaud's syndrome judged the result of sympathectomy as good.

Compensatory hyperhidrosis was experienced by two patients with dystrophy of the

hand who had removal of the second and third sympathetic ganglion.

 

PMID: 8662426 [PubMed - indexed for MEDLINE]

 

 

 

218: J Laparoendosc Surg  1996 Jun;6(3):151-9

 

A simplified T2-T3 thoracoscopic sympathicolysis technique for the treatment of

essential hyperhidrosis: short-term results in 100 patients.

 

Noppen M, Herregodts P, D'Haese J, D'Haens J, Vincken W.

 

Respiratory Department, Academic Hospital A.Z.-V.U.B., Free University of

Brussels, Belgium.

 

A simplified one-time bilateral thoracoscopic T2-T3 sympathicolysis technique

using single-lumen endotracheal intubation with high frequency jet ventilation

and electrocautery destruction ("sympathicolysis") of the sympathetic ganglia

was applied in 100 consecutive patients with severe essential hyperhidrosis

(EH). Providing a pleural space can be created, this technique was proven simple

and safe, and short-term clinical results were excellent: palmar hyperhidrosis

was cured in 98% of patients, and axillar and plantar improvement was achieved

in 62 and 65% of patients, respectively. Side-effects and complications were

minor (compensatory hyperhidrosis) or self-limiting (pain). These data confirm

the safety and efficacy of thoracoscopic sympathetic interventions for the

treatment of EH, and support the evolution toward simplified methodologies.

 

PMID: 8807515 [PubMed - indexed for MEDLINE]

 

 

 

219: J R Coll Surg Edinb  1996 Jun;41(3):160-3

 

Comment in:

 J R Coll Surg Edinb. 1997 Aug;42(4):287-8.

 

Assessment of outcome after thoracoscopic sympathectomy for hyperhidrosis in a

specialized unit.

 

Graham AN, Owens WA, McGuigan JA.

 

Regional Thoracic Surgery Department, Royal Victoria Hospital, Belfast UK.

 

Transthoracic endoscopic electrocautery of the sympathetic chain is increasingly

being used as a technique for producing the effects of upper thoracic

sympathectomy. In November 1990 we introduced this operation as a regional

service in Northern Ireland and have assessed the results in patients with

idiopathic hyperhidrosis of the palms and axillae. There were 92 sympathectomics

carried out for hyperhidrosis on 47 patients between 26 November 1990 and 6

September 1993. Full follow-up was possible in 45 patients (96%) at a median of

13 months (range 3-36) after the operation. Symptoms were improved in 43

patients (96%) at review. In three patients surgery failed to control symptoms

on one side, and in two there was bilateral recurrence at 4 and 8 months after

initial good results. Compensatory hyperhidrosis occurred in 35 patients (56%)

and was severe in 4 (9%). Nine of 34 patients (34%) with plantar symptoms

reported improvement in these post-operatively. This paper, with its high level

of full follow-up, confirms thoracoscopic sympathectomy to be effective

treatment for both palmar and axillary hyperhidrosis. Patient selection,

however, is important and the risk of compensatory hyperhidrosis must be fully

explained.

 

PMID: 8763178 [PubMed - indexed for MEDLINE]

 

 

 

220: Muscle Nerve  1996 May;19(5):581-6

 

Abolition of sympathetic skin responses following endoscopic thoracic

sympathectomy.

 

Lefaucheur JP, Fitoussi M, Becquemin JP.

 

Department of Physiology, Henri Mondor Hospital, Creteil, France.

 

The recording of sympathetic skin responses (SSRs) is a simple,

electrophysiological method to assess sympathetic nerve function. Within the

last 10 years, SSRs have mainly been applied to delineate peripheral and central

nervous system diseases, although the sympathetic nature of these responses was

not fully documented, e.g., by a study of sympathectomy. We therefore recorded

SSRs before and after 30 cases of endoscopic thoracic sympathectomy. The main

indication was palmar hyperhidrosis, in which we found two types of SSR

abnormalities. Most patients exhibited normal SSR waveforms but with increased

amplitudes. The other patients exhibited abnormal SSRs which did not occur as

single responses but as several consecutive waves. Thoracic sympathectomy always

led to significant clinical improvement and to the abolition of ipsilateral

palmar SSRs, demonstrating the sympathetic origin of these responses. We suggest

that the assessment of sympathetic nerve activity by SSR recordings may be

useful in sympathectomy.

 

PMID: 8618555 [PubMed - indexed for MEDLINE]

 

 

 

221: Arch Surg  1996 Apr;131(4):355-9

 

Technical considerations in endoscopic cervicothoracic sympathectomy.

 

Josephs LG, Menzoian JO.

 

Section of Vascular Surgery, Center of Minimal Access Surgery, Department of

General Surgery, Boston University School of Medicine, Mass, USA.

 

OBJECTIVE: To evaluate the technique and results of videoendoscopic

cervicothoracic sympathectomy in patients who have reflex sympathetic dystrophy

or hyperhidrosis of the upper extremity. DESIGN: Clinical case series. The

cohort underwent diagnostic evaluation and surgical intervention, and had a mean

postoperative follow-up of 14 months. SETTING: An urban, university-affiliated

tertiary referral medical center. PATIENTS: A consecutive, referred sample.

Seven of the nine patients had reflex sympathetic dystrophy and two had

bilateral upper extremity hyperhidrosis. Five were women and four were men, with

a mean age of 44 years. INTERVENTIONS: Ten thoracoscopic sympathectomies,

encompassing the lower third of the stellate ganglion to the fourth thoracic

ganglion, in nine patients. The technique is performed under general anesthesia,

using three 1-cm incisions for instrument placement. Patients had bilateral hand

temperature probes intraoperatively. Six of the procedures were in the left

hemithorax, four in the right. MAIN OUTCOME MEASURES: Relief of the symptoms for

which the patient was referred. Perfection and alteration of the technique also

were measured. RESULTS: The average operating time was 91 minutes. The average

length of hospital stay was 3.5 days. The mean increase in skin temperature was

2.4 degrees C. Nine of 10 patients had partial or complete relief of symptoms.

One patient with severe dystrophic reflex sympathetic dystrophy has persistent

symptoms. One patient had a pneumothorax for 48 hours. Horner's syndrome did not

develop in any patient. CONCLUSION: Endoscopic cervicothoracic sympathectomy is

an effective, minimally invasive therapy for upper extremity reflex sympathetic

dystrophy and hyperhidrosis.

 

PMID: 8615718 [PubMed - indexed for MEDLINE]

 

 

 

222: Neurosurgery  1996 Apr;38(4):715-25

 

Comment in:

 Neurosurgery. 1997 Jan;40(1):216-7.

 

Percutaneous radiofrequency upper thoracic sympathectomy.

 

Wilkinson HA.

 

Division of Neurological Surgery, University of Massachusetts Medical School,

Worchester, USA.

 

Between June 1979 and May 1994, I performed 148 unilateral or bilateral

sympathectomies on 247 limbs in 110 patients using a percutaneous radiofrequency

technique, usually on an outpatient surgery basis. Patient ages ranged from 10

to 81 years, with 45 male and 65 female patients. Four patients had

unsuccessfully undergone prior open surgical sympathectomy. Patients suffered

from hyperhidrosis, vascular occlusion, Raynaud's disease or other chronic

vasculopathies, painful causalgia or reflex sympathetic dystrophy, or

Prinzmetal's angina. The sympathectomy technique has evolved over this 15-year

period and is currently in its third phase. Changes in the procedure were based

on anatomic and clinical/radiographic correlations and careful patient

follow-up. Current modifications have reduced the frequency of both early and

late failures. The present technique (Phase III) relies on neuroleptanalgesia

with superficial local anesthesia only and does not require general anesthesia,

intubation, or lung collapse. Two 18-gauge radiofrequency TIC needle electrodes

(Radionics, Burlington, MA) are used. A series of three lesions is

rostrocaudally made at each of the ganglion sites selected in an attempt to

destroy the entire fusiform ganglion. Lesion sites are targeted by C-arm

fluoroscopy and electrical stimulation, which produces a threshold of sensory

awareness of > 1.0 V. Lesion effectiveness is monitored by bilateral finger

plethysmography and hand skin temperature measurement. With the Phase III

technique, the sympathetic activity in 96% of operated limbs after 2 years and

in 91% of operated limbs after 3 years continues to be completely or largely

interrupted. By comparison, I achieved similar success in 83 and 72% operated

limbs with the Phase I technique and in 77 and 71% with the Phase II technique.

Symptomatic pneumothorax, in six patients, has been the only serious

complication. When necessary, a subsequent operation can easily be performed and

is effective.

 

PMID: 8692390 [PubMed - indexed for MEDLINE]

 

 

 

223: Acta Anaesthesiol Sin  1996 Mar;34(1):21-5

 

Interpleural bupivacaine for pain relief after transthoracic endoscopic

sympathectomy for primary hyperhidrosis.

 

Lieou FJ, Lee SC, Ho ST, Wang JJ.

 

Division of Anesthesiology, 804 Army General Hospital, Taipei, Taiwan, R.O.C.

 

BACKGROUND: Interpleural local anesthetic has been reported to provide good

postoperative pain relief in patients receiving thoracotomy or upper abdominal

surgery. However, there were few reports regarding interpleural local anesthetic

for postoperative pain relief in patients receiving transthoracic endoscopic

sympathectomy for palmar hyperhidrosis. The aim of the present study was to

evaluate the effect of interpleural bupivacaine for postoperative pain relief in

patients receiving transthoracic endoscopic sympathectomy for palmar

hyperhidrosis. METHODS: Sixty adult patients undergoing bilateral transthoracic

endoscopic sympathectomy were randomly divided into two groups (n = 30, each

group) for study. At the end of surgery, patients in group 1 were given

bilaterally an injection of 0.5% interpleural bupivacaine (10 ml) through the

surgical endoscope, whereas those in the group 2 who were not given any

treatment at the juncture served as control. Postoperatively, intravenous

morphine 2.5 mg was given luxuriously to the patients at their request at

intervals of 30 min. The intensity of postoperative pain was assessed at rest

and during cough with visual analogue scale (VAS, 0-10 points). RESULTS: It was

showed that at rest the pain scores were less in group 1 than in group 2 within

4 h postoperatively. During cough, group 1 also had less VAS scores than group 2

within 5 h postoperatively. Furthermore, patients in group 1 consumed less

intravenous morphine than those in group 2 within 6 h postoperatively.

CONCLUSIONS: Interpleural bupivacaine significantly decreased the intensity of

postoperative pain and morphine consumption in patients undergoing transthoracic

endoscopic sympathectomy for palmar hyperhidrosis. We are looking forward to

seeing that with the addition of epinephrine to the anesthetic solution and a

considerable increase of dosage and/or volume of bupivacaine may provide a

better and longer pain relief, about which further studies are needed.

 

Publication Types:

Clinical Trial

Randomized Controlled Trial

 

PMID: 9084515 [PubMed - indexed for MEDLINE]

 

 

 

224: J Neurosurg  1996 Mar;84(3):484-6

 

Video endoscopic sympathectomy for palmar hyperhidrosis.

 

Lee KH, Hwang PY.

 

Department of Neurosurgery, Tan Tock Seng Hospital, Singapore.

 

Palmar hyperhidrosis has been treated using a variety of medical and surgical

techniques with varying degrees of success. The authors report their experience

in 82 patients in whom they performed 164 sympathectomies using a video

endoscope, a laparoscopic grasper, and microscissors. Patients were monitored by

palm temperature electrodes. An intraoperative histological confirmation of the

sympathetic chain and a temperature rise of at least 1 degree C after the

procedure resulted in complete relief of the hyperhidrosis. All the patients

were relieved of their symptoms, and 41 experienced decreased plantar

hyperhidrosis as well. Compensatory hyperhidrosis in 50 patients was the only

significant side effect, which improved 6 months after the surgery. Video

endoscopic thoracic sympathectomy is a safe, easy, reliable, and cost-effective

way to treat palmar hyperhidrosis.

 

Publication Types:

Clinical Trial

 

PMID: 8609562 [PubMed - indexed for MEDLINE]

 

 

 

225: J Vasc Surg  1996 Mar;23(3):539-40

 

Disadvanyages of previous phenol blocks in thoracoscopic upper dorsal

sympathectomy.

 

Kopelman D, Hashmonai M.

 

Publication Types:

Letter

 

PMID: 8601903 [PubMed - indexed for MEDLINE]

 

 

 

226: S Afr J Surg  1996 Feb;34(1):11-4, 16; discussion 16, 18

 

Endoscopic transthoracoscopic sympathectomy--the Durban experience.

 

Singh B, Haffejee AA, Moodley J, Naidu AG, Rajaruthnam P.

 

Department of Surgery, University of Natal, Durban.

 

Advances in optics, illumination and video-technology together with refinements

in operative technique have made endoscopic transthoracoscopic sympathectomy

(ETS) the method of choice for upper thoracic sympathectomy. Palmar

hyperhidrosis is by far the main indication for ETS. The procedure is

technically easy and well tolerated by patients, and complications are few and

minor.

 

PMID: 8629183 [PubMed - indexed for MEDLINE]

 

 

 

227: Acta Clin Belg  1996;51(4):244-53

 

Thoracoscopic sympathicolysis for essential hyperhidrosis: immediate and one

year follow-up results in 35 patients and review of the literature.

 

Noppen M, Vincken W, Dhaese J, Herregodts P, D'haens J.

 

Respiratory Division, Academic Hospital AZ-VUB, Vrije Universiteit Brussel,

Belgium.

 

Various treatments for essential hyperhidrosis are available. The aim of this

study is to present our experience with a simplified thoracoscopic

sympathicolysis technique in this disorder, and to confront our results with

data in the literature, 35 consecutive patients (11 male, 24 female, age 12-44

years) with essential hyperhidrosis, refractory to "conventional" medical

treatment presenting between August 1993 and May 1994 were studied. Bilateral

D2-D3 sympathicolysis was performed using a simplified one-time bilateral

thoracoscopic procedure under general anaesthesia. Clinical scores,

complications and side effects were recorded one week, one month and one year

after the intervention. Severe hyperhidrosis was present in the hands in 100%,

axillae in 66% and soles of the feet in 86% of patients. In one patient, only a

unilateral intervention was possible due to pleural adhesions. In the other 34

patients, palmar hyperhidrosis was completely and permanently relieved in 100%

of cases. Axillar hyperhidrosis was significantly improved after one year in 91%

of patients, 52% of which showed a complete disappearance of hyperhidrosis. Side

effects and complications were minimal. There were no permanent pleural,

neurological (Horner) or other sequellae. Patient satisfaction was invariably

very high. These findings compare favourably with historical data in the

literature.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 8858890 [PubMed - indexed for MEDLINE]

 

 

 

228: Eur J Cardiothorac Surg  1996;10(3):168-72

 

Endoscopic versus transaxillary thoracic sympathectomy for primary axillary and

palmar hyperhidrosis and/or facial blushing: 5-year-experience.

 

Yilmaz EN, Dur AH, Cuesta MA, Rauwerda JA.

 

Department of Vascular Surgery, Free University Hospital, Amsterdam, The

Netherlands.

 

Thoracic sympathectomy is effective in the permanent cure of primary axillary

and palmar hyperhidrosis and facial blushing, which can be so troublesome for

patients that their social and professional relations can be affected. Between

October 1988 and April 1994, a total of 50 thoracic sympathectomies (10 surgical

and 40 endoscopic) were performed on 5 and 23 patients, respectively. The

operations were performed unilaterally, followed by the contralateral

intervention after a period of 6-8 weeks. The thoracic ganglia T2-T5 were

resected for hyperhidrosis. If the patient suffered from blushing, the lower 1/3

of the stellate ganglion was also resected. Postoperatively, all the operated

limbs were warm and dry. In the group of patients who were operated bilaterally,

only one had persistent facial blushing. The efficacy for blushing in this

series was therefore 93.3%. The late relapse rate of sympathetic activity was

14.3%. Compensatory sweating was seen in 67%, gustatory sweating in 37.5% and

phantom sweating in 29% of the patients. None of them considered these side

effects to be troublesome. Although there is no difference between transaxillary

thoracic sympathectomy and the endoscopic intervention in terms of efficacy, the

latter is associated with less postoperative pain, shorter hospital stay and a

rapid recovery. The thoracic sympathectomy is the treatment of choice for

primary hyperhidrosis and excessive facial blushing.

 

PMID: 8664016 [PubMed - indexed for MEDLINE]

 

 

 

229: Khirurgiia (Mosk)  1996;(1):63-5

 

[Thoracoscopic sympathectomy in the surgical treatment of axillary and palmar

hyperhidrosis]

 

[Article in Russian]

 

Anikin V, Graham A, MacGuigan D.

 

47 patients with axillary palmar hyperhydrosis underwent this surgery. There

were 36 women (76.6%) and 11 men (23.4%) among them. The sympathetic trunk has

been coagulated on the level between 2d and 4th ribs on both sides. There were

no surgical mortality in this group. Nine patients (9.1%) had a pneumothorax,

one patient (2.1%) had a subcutaneous emphysema, the other one had pneumonia and

one had wound pyosis. In 43 cases the result of the surgery was very good. In 2

cases bilateral relapse and in 2 cases marked compensatory hyperhydrosis were

resistered.

 

PMID: 8683926 [PubMed - indexed for MEDLINE]

 

 

 

230: Somatosens Mot Res  1996;13(2):147-52

 

Sympathectomy does not influence experimental itch and cutaneous temperature

perception thresholds.

 

Ekblom A, Lind G, Meyerson BA, Lengstam I, Wahlgren CF.

 

Department of Anaesthesiology and Intensive Care, Karolinska Hospital,

Stockholm, Sweden.

 

The effect of endoscopic thoracic sympathectomy on experimentally

histamine-induced itch was studied in seven patients, all of whom were suffering

from palmar hyperhidrosis; cutaneous warm, cold, and heat pain perception

thresholds were also studied in five of these seven patients. Surgery was

effective in abolishing palmar sweating in all patients. No significant

differences were seen in itch, flare, wheal, or thermal perception thresholds

following sympathectomy as compared to the preoperative period. These findings

suggest that the sympathetic system may be of limited importance for

somatosensory perception in healthy humans during normal conditions.

 

PMID: 8844963 [PubMed - indexed for MEDLINE]

 

 

 

231: Arch Surg  1995 Nov;130(11):1244

 

Comment on:

 Arch Surg. 1994 Jun;129(6):630-3.

 

Transthoracic endoscopic sympathectomy in the treatment of palmar hyperhidrosis.

 

Kao MC.

 

Publication Types:

Comment

Letter

 

PMID: 7487471 [PubMed - indexed for MEDLINE]

 

 

 

232: Lakartidningen  1995 Oct 4;92(40):3661

 

Comment on:

 Lakartidningen. 1995 May 31;92(22):2310-2

 

[Misleading information about patients with palmar sweating]

 

[Article in Swedish]

 

Koskinen LO, Algers G.

 

Publication Types:

Comment

Letter

 

PMID: 7564608 [PubMed - indexed for MEDLINE]

 

 

 

233: Ann Clin Biochem  1995 Sep;32 ( Pt 5):509-10

 

Hyperhidrosis and iron deficiency.

 

Labib M, Obeid D.

 

Department of Clinical Biochemistry, Russells Hall Hospital, Dudley, West

Midlands, UK.

 

PMID: 8830629 [PubMed - indexed for MEDLINE]

 

 

 

234: Muscle Nerve  1995 Aug;18(8):917-9

 

Abnormal sympathetic skin response in patients with palmar hyperhidrosis.

 

Lin TK, Chee EC, Chen HJ, Cheng MH.

 

Department of Neurology, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.

 

PMID: 7630357 [PubMed - indexed for MEDLINE]

 

 

 

235: J Am Acad Dermatol  1995 Jul;33(1):78-81

 

Endoscopic transthoracic sympathectomy: an efficient and safe method for the

treatment of hyperhidrosis.

 

Drott C, Gothberg G, Claes G.

 

Department of Surgery, Boras Hospital, Sweden.

 

BACKGROUND: Hyperhidrosis of the palms, axillae, and face has a strong negative

impact on the quality of life for many persons. Existing nonsurgical therapeutic

options are far from ideal. Definitive cure can be obtained by upper thoracic

sympathectomy. The traditional open surgical technique is a major procedure; few

patients and doctors have found that risk-benefit considerations favor surgery.

Endoscopic minimal invasive surgical techniques are now available. OBJECTIVE: We

investigated whether endoscopic ablation of the upper thoracic sympathetic chain

is efficient and safe in the treatment of hyperhidrosis. METHODS: We treated 850

patients with bilateral endoscopic transthoracic sympathectomy. RESULTS: There

was no mortality or life-threatening complication. Nine patients (1%) required

intercostal drainage because of hemothorax or pneumothorax. Treatment failure

occurred in 18 cases (2%) and symptoms recurred in 17 patients (2%). At the end

of follow-up (median, 31 months) 98% of the patients reported satisfactory

results. CONCLUSION: Endoscopic transthoracic sympathectomy is an efficient,

safe, and minimally invasive surgical method for the treatment of palmar,

axillary, and facial hyperhidrosis.

 

Publication Types:

Clinical Trial

 

PMID: 7601951 [PubMed - indexed for MEDLINE]

 

 

 

236: Acta Anaesthesiol Sin  1995 Jun;33(2):73-7

 

Intravenous tenoxicam reduces dose and side effects of PCA morphine in patients

after thoracic endoscopic sympathectomy.

 

Liaw WJ, Day YJ, Wang JJ, Ho ST.

 

Department of Anesthesiology, Tri-Service General Hospital, Taipei, Taiwan,

R.O.C.

 

BACKGROUND: Among surgical modalities for treatment of palmar hyperhidrosis,

endoscopic sympathectomy is the most popular choice in recent years. After

surgery, the major complaint was anterior chest pain. This study was conducted

to evaluate the analgesic efficacy and side effects of tenoxicam (a

thienothiazine derivative) in combination with patient-controlled analgesia

(PCA) using morphine in patients who received thoracic endoscopic sympathectomy.

METHODS: Forty-one ASA class I patients who underwent endoscopic sympathectomy

(T2 and T3 ganglia) were randomly divided into two groups. Operation was

conducted under general anesthesia with single lumen endotracheal intubation. No

narcotic was given during the operation except for fentanyl (3 micrograms/kg)

during induction. After surgery, patients in group I received PCA morphine only

and patients in group II received PCA morphine plus tenoxicam (20 mg, i.v.)

immediately for pain relief. In addition, rescue analgesia with intramuscular

meperidine (1 mg/kg) was available to each patient every 4 h prn. The intensity

of pain was assessed with VAS pain score every 4 h for 24 h. The frequency of

demand and doses of delivered PCA morphine were recorded. RESULTS: Results

showed no statistically significant difference between groups in respect of age,

body height, body weight and pain scores. However, based upon similar

qualitative pain relief, patients in group II revealed less demand for

analgesic, less doses of morphine requirement and less side effects.

CONCLUSIONS: Tenoxicam may be an effective adjuvant to PCA morphine for

postoperative pain control. This combination reduces the total consumption of

PCA morphine with less side effects.

 

Publication Types:

Clinical Trial

Randomized Controlled Trial

 

PMID: 7663867 [PubMed - indexed for MEDLINE]

 

 

 

237: Acta Anaesthesiol Sin  1995 Jun;33(2):113-8

 

[Changes of arterial oxygen tension in supine position during one-lung

anesthesia]

 

[Article in Chinese]

 

Day YB, Lee CG, Tseng CC, Chiang MH, Chang CL.

 

Department of Anesthesiology, Navy General Hospital, Tainan, Taiwan, R.O.C.

 

BACKGROUND: One-lung ventilation during anesthesia (one-lung anesthesia) in

patients under lateral decubitus position to help performing intra-thoracic

surgical procedures was well known to have larger alveolar-to-arterial oxygen

tension difference and lower arterial oxygen tension (PaO2) as compared to

two-lung ventilation. In the present study, we investigate the changes of

arterial oxygen tension in the supine position during one-lung anesthesia.

METHODS: Forty-two patients of palmar hyperhidrosis, ASA class I-II, scheduled

to receive bilateral transthoracic endoscopic sympathectomy were studied. After

anesthetic induction (fentanyl, thiopental, and succinylcholine), a 35 (for

female) or 37 (for male) French left-sided Robertshaw double-lumen endobronchial

tube was intubated. Anesthesia was maintained with isoflurane 1.0-1.5% and 50%

O2-N2O. They were changed to isoflurane 1.5-2.0% and 100% O2 during one-lung

ventilation. Once the surgical operation is completed, they were changed to 100%

O2 and two-lung ventilation. Arterial blood gases were measured at 4 phases: 5

min after endobronchial intubation (two-lung ventilation), 5 min after left

one-lung ventilation, 5 min after right one-lung ventilation, and 5 min after

accomplishing operation (two-lung ventilation). RESULTS: The results showed PaO2

were significantly lower in left and right one-lung ventilation with 100% O2 as

compared with that obtained from two-lung ventilation with 50% O2 5 min after

endobronchial intubation (p < 0.05). Furthermore, right one-lung ventilation had

a lower PaO2 than left one-lung ventilation (p < 0.05). CONCLUSIONS: We conclude

that arterial oxygen tension can be safely maintained during one-lung anesthesia

with pure oxygen in healthy patients lying in a supine position.

 

PMID: 7663862 [PubMed - indexed for MEDLINE]

 

 

 

238: Lakartidningen  1995 May 31;92(22):2310-2

 

Comment in:

 Lakartidningen. 1995 Oct 4;92(4):3661

 

[Hand perspiration was his death. The cause was sympathetic imbalance]

 

[Article in Swedish]

 

Hedman A.

 

Medicinska kliniken, Ludvika lasarett.

 

PMID: 7783492 [PubMed - indexed for MEDLINE]

 

 

 

239: Clin Exp Dermatol  1995 May;20(3):230-3

 

Recurrence of hyperhidrosis after endoscopic transthoracic sympathectomy--case

report and review of the literature.

 

Orteu CH, McGregor JM, Almeyda JR, Rustin MH.

 

Dermatology Department, Royal Free Hospital, London, UK.

 

Publication Types:

Review

Review of Reported Cases

 

PMID: 7671419 [PubMed - indexed for MEDLINE]

 

 

 

240: J Auton Nerv Syst  1995 Apr 8;52(2-3):117-24

 

Mechanisms of physiological gustatory sweating and flushing in the face.

 

Drummond PD.

 

Division of Psychology, Murdoch University, Perth, Western Australia.

 

Mechanisms of physiological gustatory sweating and flushing were investigated in

21 patients with a facial nerve lesion compromising parasympathetic outflow to

the lacrimal gland, and in 13 patients undergoing diagnostic blockade of the

stellate ganglion. Vascular responses and electrodermal activity (which reflects

sweating) were monitored on each side of the forehead before and during

gustatory stimulation with chillies or Tabasco sauce (derived from chillies).

Vascular responses in the cheeks were also monitored in 14 patients with a

facial nerve lesion. Sympathetic blockade increased gustatory vasodilatation but

prevented gustatory sweating on the blocked side of the forehead. A facial nerve

lesion did not affect gustatory sweating in the forehead or vasodilatation in

the cheeks. However, a facial nerve lesion impaired vasodilatation in the

forehead in all six patients who ate chillies, and also in four of five patients

whose blood vessels dilated extensively on the normally-innervated side of the

forehead when the patients tasted Tabasco sauce. These findings suggest that

sympathetic sudomotor activity mediates physiological gustatory sweating in the

forehead, whereas sympathetic vasoconstrictor tone inhibits gustatory

vasodilatation in the forehead. A parasympathetic vasodilator reflex in the

facial nerve contributes actively to gustatory flushing in the forehead, but

some other unidentified mechanism influences vascular responses in the cheeks.

 

Publication Types:

Clinical Trial

 

PMID: 7615894 [PubMed - indexed for MEDLINE]

 

 

 

241: J Chir (Paris)  1995 Apr;132(4):222-3

 

[Palmar hyperhidrosis and arteritis of the finger: value of sympathectomy and

videothoracoscopy]

 

[Article in French]

 

Mouroux J, Bernard JL, Hassen Kodja R, Batt M, Lebas P, Richelme H.

 

Publication Types:

Letter

 

PMID: 7635902 [PubMed - indexed for MEDLINE]

 

 

 

242: Lancet  1995 Mar 25;345(8952):803-4

 

Comment on:

 Lancet. 1995 Jan 14;345(8942):97-8.

 

Thoracoscopic sympathicotomy.

 

Noppen M, Dendale P, Hagers Y.

 

Publication Types:

Comment

Letter

 

PMID: 7891518 [PubMed - indexed for MEDLINE]

 

 

 

243: Acta Anaesthesiol Sin  1995 Mar;33(1):21-6

 

Use of a single lumen endotracheal tube and continuous CO2 insufflation in

transthoracic endoscopic sympathectomy.

 

Wong RY, Fung ST, Jawan B, Chen HJ, Lee JH.

 

Department of Anesthesiology, Chang-Gung Memorial Hospital, Taiwan, R.O.C.

 

BACKGROUND: Transthoracic endoscopic sympathectomy (TES) is an accepted standard

surgical treatment for palmar hyperhidrosis. For anesthetic management, a double

lumen endobronchial tube is usually used to deflate the lung on the operative

side. Recently we have applied continuous insufflation of carbon dioxide (CO2)

into the pleural cavity to merely compress one lung while ventilating both lungs

with a conventional single lumen endotracheal tube. METHODS: We have studied 45

patients (ASA I and II) who underwent bilateral TES, Thirty-three were

ventilated by single lumen tube and the other 12 by double lumen endobronchial

tube with one lung ventilation. In both groups I and II, CO2 was insufflated

slowly through the scope to a intrapleural pressure of 20 cm H2O. Both lungs

were ventilated with peak pressure of less than 20 cmH2O at tidal volume of 5-12

ml/kg at 10-16 beats/min. RESULTS: In these patients, no CO2 retention was

noted. Oxygenation and cardiovascular stability were maintained and there were

no complications. In the double lumen series, we found that oxygen saturation

was less uniform and less stable than those in the single lumen series.

CONCLUSIONS: It is concluded that the use of single lumen endotracheal tube with

continuous insufflation of CO2 in TES is easy, simple and safe.

 

PMID: 7788194 [PubMed - indexed for MEDLINE]

 

 

 

244: J Pediatr Surg  1995 Mar;30(3):471-3

 

Thoracoscopic upper thoracic sympathectomy for primary palmar hyperhidrosis in

children and adolescents.

 

Cohen Z, Shinar D, Levi I, Mares AJ.

 

Department of Pediatric Surgery, Soroka Medical Center, Faculty of Health

Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

 

After 20 years of experience with the "open" transaxillary approach, the authors

are presently performing the thoracoscopic technique for upper thoracic

sympathectomy in severe primary hyperhidrosis. During a period of 14 months, 23

operations were performed and 22 patients had immediate and permanent relief of

palmar sweating. The immediate postoperative course was uneventful in all cases.

Hospitalization was short, and all patients returned to school and full activity

3 to 5 days after operation. These initial results compare favorably to the

"open" method and, pending further experience, are actually better in terms of

less pain, early discharge, quicker return to normal activity, and a smaller,

less conspicuous scar.

 

PMID: 7760245 [PubMed - indexed for MEDLINE]

 

 

 

245: Br J Anaesth  1995 Feb;74(2):141-4

 

Tracheal anaesthesia for transthoracic endoscopic sympathectomy: an alternative

to endobronchial anaesthesia.

 

Olsfanger D, Jedeikin R, Fredman B, Shachor D.

 

Department of Anaesthesia and Intensive Care, Meir Hospital, Kfar Saba, Israel.

 

When using endobronchial anaesthesia for the management of transthoracic

endoscopic sympathectomy (TES), excessive insufflation of carbon dioxide into

the pleural space may cause haemodynamic instability, hypoxaemia and tension

pneumothorax. We prospectively studied an alternative technique using a tracheal

tube, i.v. fentanyl, propofol, atracurium and nitrous oxide in 82 consecutive

healthy patients (31 male, 51 female; mean age 26.48 (range 14-50) yr, weight

61.26 (33-100)kg.) They were suffering from severe palmar hyperhidrosis and they

underwent bilateral TES (mean duration of operation 34.57 (15-90) min). After

being placed in a 30-40 degree head-up position, three patients required

ephedrine to treat arterial hypotension. A capnograph was used to confirm

correct placement of the Verres needle in the pleural space. In two groups of 13

patients undergoing ventilation with an FlO2 of either 0.3 or 0.4, during

partial collapse of the operative lung, PaO2 and the PaO2:FlO2 ratio decreased

significantly (P < 0.001). TES was unsuccessful in three patients because of

pleural adhesions. After operation five patients required chest drains; two for

haemothorax and three for pneumothorax. Seventy-seven patients without

complications were discharged from hospital within 24 h.

 

Publication Types:

Clinical Trial

Controlled Clinical Trial

 

PMID: 7696060 [PubMed - indexed for MEDLINE]

 

 

 

246: J Am Coll Surg  1995 Feb;180(2):253-4

 

Comment on:

 J Am Coll Surg. 1994 Jul;179(1):59-64.

 

Video-assisted thoracoscopic T2 sympathectomy for hyperhidrosis palmaris.

 

Kopelman D, Assalia A, Hashmonai M.

 

Publication Types:

Comment

Letter

 

PMID: 7850067 [PubMed - indexed for MEDLINE]

 

 

 

247: Ann Chir  1995;49(9):858-62

 

[Upper thoracic sympathectomy by thoracoscopic approach. A method of choice for

the treatment of palmar hyperhidrosis]

 

[Article in French]

 

Levy I, Ariche A, Sebbag G, Khodda J.

 

Service de Chirurgie A, Chirurgie Generale et Vasculaire, Centre

Hospitalo-Universitaire Soroka, Universite Ben-Gourion du Neguev, Beer Sheva,

Israel.

 

Palmar hyperhidrosis is excessive sweating beyond physiological needs in the

palm without recognized etiology. Although a benign disease, it is annoying to

most patients. Currently the best treatment for this condition is upper thoracic

sympathectomy via many different approaches. The video-thoracoscopic approach

has been recommended a a minimally invasive procedure. We report our 1-year

experience with transaxillary endoscopic sympathectomy in 99 patients with

palmar hyperhidrosis. Standard video-laparoscopy was used via a transaxillary

approach to perform sympathectomy. The mean operating time of this operation was

12 minutes and mean hospital stay was 32 hours. The results in terms of warm and

dry hands were excellent. Only one case of transitory Horner syndrome was noted.

Transaxillary thoracoscopic sympathectomy for palmar hyperhidrosis is a

relatively simple and effective procedure which can be performed with standard

laparoscopic instruments. The advantages are, short recovery time and hospital

stay along with excellent functional and cosmetic results. We are convinced that

thoracoscopic sympathectomy is the procedure of choice for the treatment of

palmar hyperhidrosis.

 

Publication Types:

Review

Review Literature

 

PMID: 8554286 [PubMed - indexed for MEDLINE]

 

 

 

248: Ann R Coll Surg Engl  1995 Jan;77(1):70

 

Comment on:

 Ann R Coll Surg Engl. 1994 Sep;76(5):311-4.

 

Endoscopic transthoracic sympathectomy: successful in hyperhidrosis but can the

indications be extended?

 

Cameron A.

 

Publication Types:

Comment

Letter

 

PMID: 7772180 [PubMed - indexed for MEDLINE]

 

 

 

249: Arch Phys Med Rehabil  1995 Jan;76(1):104-7

 

Gustatory facial sweating subsequent to upper thoracic sympathectomy.

 

Nesathurai S, Harvey DT, Schatz SW.

 

Department of Physical Medicine and Rehabilitation, McMaster University,

Hamilton, Ontario, Canada.

 

Gustatory facial sweating has been described as a consequence of upper thoracic

sympathectomy. Patients may also develop compensatory hyperhidrosis, sensory

deficits, nipple hypersensitivity, and Horner's syndrome. In this article, we

have reviewed three patients with reflex sympathetic dystrophy who developed

gustatory facial sweating subsequent to endoscopic T2 and T3 ganglionectomy.

This article also discusses the possible mechanisms of gustatory facial

sweating.

 

PMID: 7811168 [PubMed - indexed for MEDLINE]

 

 

 

250: Stereotact Funct Neurosurg  1995;64(4):214-20

 

Recordings of pre- and postoperative sympathetic skin response in patients with

palmar hyperhidrosis.

 

Chen HJ, Cheng MH, Lin TK, Chee EC.

 

Department of Neurosurgery, Chang Gung Medical College, Taiwan, R.O.C.

 

Transthoracic endoscopic sympathectomy is an accepted standard surgical

treatment for hyperhidrosis palmaris. During the past 4 years, more than 500

patients underwent this kind of surgical treatment at our institution with a 98%

success rate. About 50% of cases were found to have compensatory sweating. We

measured the sympathetic skin response (SSR) and R-R interval variation (RRIV)

in 38 normal control subjects, and 50 consecutive patients with palmar

hyperhidrosis before and 2 weeks after transthoracic endoscopic T2-3

sympathectomy. Before sympathectomy SSR was absent in 36% of patients on deep

inspiratory stimulation and in 20% on electrical stimulation. After T2-3

sympathectomy, SSR in the palms was absent in 64% of patients with deep

inspiration stimulation and in 76% on electrical stimulation. A decrease in the

SSR amplitude in the soles was found in 40% on deep inspiration and in 54% of

patients on electrical stimulation. RRIV was not significantly influenced 2

weeks after sympathectomy. The high abnormal rate of SSR in the patient group

indicated that an abnormal regulation of the sudomotor control center played an

important role in palmar hyperhidrosis.

 

PMID: 8817808 [PubMed - indexed for MEDLINE]

 

 

 

251: Otolaryngol Head Neck Surg  1994 Dec;111(6):838-40

 

Nasal obstruction and Horner's syndrome.

 

Shaari CM, Scherl MP.

 

Department of Otolaryngology, Mount Sinai School of Medicine, City University of

New York, NY 10029-6574.

 

Publication Types:

Review

Review of Reported Cases

 

PMID: 7991269 [PubMed - indexed for MEDLINE]

 

 

 

252: Acta Physiol Scand  1994 Nov;152(3):259-63

 

Is palmar and plantar sweating thermoregulatory?

 

Kerassidis S.

 

Department of Basic Sciences, School of Health Science, University of Crete,

Greece.

 

We tested the hypothesis that palmar and plantar sweating has a thermoregulatory

role and is mediated by the same thermoregulatory mechanisms that control

sweating in the rest of the body surface. In a series of empirical tests

involving 34 participants (five of whom exhibited palmar hyperhydrosis), the

effect of high environmental temperature on sweating was examined. Wilcott's

finding, that effects at the palm are of considerable magnitude, was confirmed

only in subjects who were in a state of excitement. In relaxed subjects, the

effects of high environmental temperature on palmar and plantar sweating was

negligible. We conclude that the palms and soles do not directly participate in

thermoregulation.

 

PMID: 7872003 [PubMed - indexed for MEDLINE]

 

 

 

253: J Vasc Surg  1994 Oct;20(4):511-7; discussion 517-9

 

Thoracoscopic cervicodorsal sympathectomy: preliminary results.

 

Ahn SS, Machleder HI, Concepcion B, Moore WS.

 

UCLA Center for the Health Sciences.

 

PURPOSE: The purpose of this study was to determine the feasibility, safety, and

efficacy of thoracoscopic cervicodorsal sympathectomy. METHODS: From March 1990

to December 1993, we performed 21 thoracoscopic sympathectomies in 19 patients.

There were 13 women and six men; age 17 to 64 years, mean 37 years. Thirteen

procedures were performed on the left side and eight on the right. Indications

for surgery were causalgia/reflex sympathetic dystrophy in nine patients,

Raynaud's/vasculitis in six, hyperhidrosis in five, and medically refractory

cardiac arrhythmia in one. RESULTS: The T1-4 sympathetic ganglia were readily

identified, dissected free, and resected thoracoscopically in 19 cases, and the

T3-7 ganglia were resected with thoracoscopy in one case. One case required

conversion to an open thoracotomy because of dense scar from a previous first

rib resection, which obscured the anatomy. Histologic confirmation of ganglia

were obtained in all 21 cases. Operative duration ranged from 1.0 to 3.5 hours.

Estimated blood loss was 5 to 300 cc, mean 42 cc, median 10 cc. No patient

required transfusion. All 21 patients had an excellent immediate sympathectomy

response. Transient Horner's syndrome developed in two patients. Postoperative

residual pneumothorax (< 10%) occurred in three cases and resolved spontaneously

without further treatment. In one patient pleural effusion and pneumothorax

developed, which were treated with the reinsertion of the chest tube.

Postoperative pain was well controlled with oral analgesics. Hospital stay was 1

to 4 days, mean 2 days, median 1 day. Follow-up at 1 to 42 months, mean 11

months, median 6 months, showed continued evidence of sympathectomy effect in

all patients, except one who died of her underlying disease 1 month after

operation. CONCLUSIONS: We conclude that thoracoscopic sympathectomy is

feasible, safe, and effective. Further studies are indicated to confirm its

long-term benefits and to determine optimal thoracoscopic techniques.

 

Publication Types:

Clinical Trial

 

PMID: 7933252 [PubMed - indexed for MEDLINE]

 

 

 

254: Singapore Med J  1994 Oct;35(5):460-3

 

Video-assisted endoscopic thoracic sympathectomy in the management of

intractable palmar hyperhydrosis.

 

Thomas J, Pillay P, Mack P, Ooi LL, Nachiappan M.

 

Department of Neurosurgery, Singapore General Hospital.

 

Minimally invasive endoscopic surgical techniques have revolutionised patient

management. We present our findings in our first 10 cases of bilateral

video-assisted endoscopic thoracic sympathectomy in the management of

intractable palmar hyperhydrosis including the first such procedure in

Singapore. We have found the procedure to have minimal morbidity, good patient

acceptance and all patients have remained with dry palms.

 

PMID: 7701362 [PubMed - indexed for MEDLINE]

 

 

 

255: Ann R Coll Surg Engl  1994 Sep;76(5):311-4

 

Comment in:

 Ann R Coll Surg Engl. 1995 Jan;77(1):70.

 

Endoscopic transthoracic sympathectomy: successful in hyperhidrosis but can the

indications be extended?

 

Nicholson ML, Dennis MJ, Hopkinson BR.

 

Department of Surgery, University Hospital Nottingham.

 

Endoscopic transthoracic sympathectomy (ETS) has recently become established as

a successful treatment for severe palmar and axillary hyperhidrosis. In this

unit the indications for ETS have been broadened to include patients with

Raynaud's syndrome and critical upper limb ischaemia and this paper is primarily

concerned with analysing outcome in relation to the indication for operation. In

all, 68 operations have been attempted in 40 patients and complete follow-up

details are available on 62 treated limbs. One operation was a technical failure

because of an obliterated pleural cavity. In the hyperhidrosis group (n = 28),

all the affected areas showed symptomatic improvement at a median follow-up of

17 months. In the Raynaud's group (n = 30), 28 limbs (93%) were improved to some

degree at the time of discharge, but at a median follow-up of 18 months only 15

limbs (50%) remained symtomatically improved to some degree. The four upper

limbs treated for critical ischaemia were improved by ETS and no amputations

were necessary. Significant postoperative chest pain was noted by nine patients

(23%). There were three postoperative pneumothoraces, two intercostobrachial

neuralgias and one transient Horner's syndrome. The cosmetic result was reported

as excellent or good by 97% of patients. As with other forms of surgical

thoracic sympathectomy, excellent early results are not maintained in the longer

term when ETS is used to treat Raynaud's syndrome. Nevertheless, the greater

simplicity and lower morbidity of the endoscopic method suggest that it can be

offered to Raynaud's sufferers with greater impunity than open sympathectomies.

 

PMID: 7979070 [PubMed - indexed for MEDLINE]

 

 

 

256: Eur J Vasc Surg  1994 Sep;8(5):627-31

 

Comment in:

 Eur J Vasc Surg. 1995 Oct;10(3):384-5

 

Transthoracic endoscopic sympathectomy for hyperhidrosis and Raynaud's

phenomenon.

 

Sayers RD, Jenner RE, Barrie WW.

 

Department of Surgery, Leicester General Hospital, U.K.

 

Over an 80 month period, 53 transthoracic endoscopic sympathectomies were

performed in 34 patients. The indications for surgery were palmar hyperhidrosis

in 20 procedures (38%), palmar and axillary hyperhidrosis in eight procedures

(15%), Raynaud's phenomenon in 23 procedures (43%), and combined palmar

hyperhidrosis and Raynaud's phenomenon in two procedures (4%). Follow-up data,

obtained by a self-assessment postal questionnaire, was available for 47

procedures in 30 patients (91%). Fourteen out of 15 procedures (93%) performed

for palmar hyperhidrosis, all eight procedures (100%) for palmar and axillary

hyperhidrosis and 14 out of 22 procedures (64%) performed for Raynaud's

phenomenon produced an immediate improvement in symptoms. These improvements

were sustained in 13 procedures (87%) performed for palmar hyperhidrosis, all

procedures performed for palmar and axillary hyperhidrosis (100%) but only 10

procedures (45%) performed for Raynaud's phenomenon at a median follow-up of 16,

34 and 44.5 months respectively. There were no deaths nor postoperative Horner's

syndrome in these patients. The only minor complications were two small

pneumothoraces. Compensatory sweating was observed after 24 procedures (51%).

These results confirm that transthoracic endoscopic sympathectomy is a simple,

safe and effective procedure. In patients with hyperhidrosis, the results are

excellent and prolonged; in patients with Raynaud's phenomenon, immediate

improvement can be achieved but the symptoms may return with time.

 

PMID: 7813733 [PubMed - indexed for MEDLINE]

 

 

 

257: Chirurg  1994 Aug;65(8):677-9

 

[Thoracoscopic sympathicotomy]

 

[Article in German]

 

Flora G.

 

Abteilung fur Gefasschirurgie, I. Universitatsklinik fur Chirurgie Innsbruck.

 

Surgical endoscopic endothoracic denervation (severing the n. vagus and the

sympathetic trunk with the nn. splanchnici) was developed by Kux at Innsbruck

University Surgical Clinic in the 1950's and applied in thousands of patients

with a very wide range of indications. The thoracoscopic sympathicotomy has

remained, in the hands of the experienced surgeon, a minor intervention with low

complication rate and no mortality. For functional and organic angiopathies as

well as for hyperhidrosis of the upper extremities it provides very good early

and satisfactory late results.

 

PMID: 7956532 [PubMed - indexed for MEDLINE]

 

 

 

258: J Dermatol  1994 Aug;21(8):575-81

 

Sympathetic ganglion blockade for the management of hyperhidrosis.

 

Kobayashi K, Omote K, Homma E, Abe T, Iitoyo M.

 

Department of Dermatology, Sapporo Hospital of Hokkaido Railway Company, Japan.

 

We present three patients with severe primary hyperhidrosis, refractory to

conservative medical treatment, who were successfully managed with sympathetic

ganglion blockade with ethanol. We also summarize 10 patients with hyperhidrosis

who underwent sympathetic ganglion blockade in the past 2 years. This closed

percutaneous method offers the patients considerably less discomfort and less

stress with minimal morbidity and has a efficacy similar to that of surgical

sympathectomy, which has previously been the only effective and permanent

therapy for severe primary hyperhidrosis. It is concluded that chemical

sympathectomy is an effective and useful method for treating severe

hyperhidrosis which has advantages over surgical sympathectomy.

 

PMID: 7962955 [PubMed - indexed for MEDLINE]

 

 

 

259: Neurosurgery  1994 Aug;35(2):330-2; discussion 332

 

Chylothorax after endoscopic sympathectomy: case report.

 

Cheng WC, Chang CN, Lin TK.

 

Department of Surgery, Chang Gung Medical College, Taiwan, Republic of China.

 

Endoscopic sympathectomy is a new trend for the treatment of hyperhidrosis

palmaris. It is a simple and effective technique; however, it carries some

recognized risks such as Horner's syndrome and pneumohemothorax. We recently

encountered a case complicated by the development of a chylothorax. The patient

was a 23-year-old healthy women with profuse palmar sweating. She developed an

intractable dry cough after a transthoracic endoscopic sympathectomy. A chest

x-ray revealed a left pleural effusion. A chylous effusion was found after

thoracentesis and fluid analysis. The pleural effusion resolved after chest tube

drainage and diet control. Although endoscopic sympathectomy is a simple and

quick procedure, unusual complications, such as chylothorax, may occur.

Appropriate early recognition and treatment can prevent a disastrous result.

 

PMID: 7969846 [PubMed - indexed for MEDLINE]

 

 

 

260: J Am Coll Surg  1994 Jul;179(1):59-64

 

Comment in:

 J Am Coll Surg. 1995 Feb;180(2):253-4.

 

Video-assisted thoracoscopic T2 sympathectomy for hyperhidrosis palmaris.

 

Hsu CP, Chen CY, Lin CT, Wang JH, Chen CL, Wang PY.

 

Department of Surgery, Taichung Veterans General Hospital, Taiwan, Republic of

China.

 

BACKGROUND: Hyperhidrosis palmaris is a functionally and socially disabling

problem. Thoracic sympathectomy of the T2 ganglion has proved to be the

time-honored treatment modality. STUDY DESIGN: The results of this study

demonstrate the effectiveness of video-assisted thoracoscope for treatment of

hyperhidrosis palmaris. The possibility to apply different anesthetic techniques

and to measure surface temperature change of the hand were documented as well.

RESULTS: Eighty consecutive cases (159 procedures) of essential hyperhidrosis

palmaris were treated by video-assisted thoracoscopic T2 sympathectomy between

January 1991 and December 1992. The surgical results were classified as

excellent (much improved, very dry) in 88.1 percent, good (improved, minimal

wet) in 9.4 percent, and fair (slightly improved, still wet) in 2.5 percent of

the patients. The postoperative complications included one prolonged air

leakage, one hemothorax, two wound infections, and 15 cases of facial

anhidrosis. There were no recurrent cases (mean follow-up, 14.5 months).

Fifty-six patients had concomitant hyperhidrosis pedum. Interestingly enough,

through unknown mechanism, 64.3 percent of the patients with concomitant

hyperhidrosis pedum were cured after this procedure. CONCLUSIONS: Video-assisted

thoracoscopy provides magnified surgical fields, which make thoracoscopic

sympathectomy for hyperhidrosis palmaris an effective, safe, easy to use, and

time-saving procedure. This technique is also excellent for teaching purposes

and allows the assistant to participate in the operation.

 

PMID: 8019726 [PubMed - indexed for MEDLINE]

 

 

 

261: Arch Surg  1994 Jun;129(6):630-3

 

Comment in:

 Arch Surg. 1995 Nov;130(11):1244.

 

Transthoracic endoscopic sympathectomy in the treatment of palmar hyperhidrosis.

 

Chen HJ, Shih DY, Fung ST.

 

Department of Surgery, Chang Gung Medical College, Kaohsiung, Taiwan, Republic

of China.

 

OBJECTIVE: Transthoracic endoscopic electrocauterization of the sympathetic

chain for palmar hyperhidrosis is presented. DESIGN: A retrospective study of

180 patients during a 2-year period was carried out. The duration of follow-up

was from 2 to 12 months. SETTING: General community, referral center, and

hospitalized care. PATIENTS: This study was carried out in 180 patients (116

female and 64 male). The age distribution was between 13 and 43 years (mean age,

21.6 years). They complained of palmar hyperhidrosis without other underlying

diseases. INTERVENTIONS: One-stage bilateral surgery except for three patients

with unilateral pleural adhesions. MAIN OUTCOME MEASURES: Patients were

interviewed 1 week after surgery and then they were contacted by a questionnaire

about improvement of hyperhidrosis and complications. RESULTS: This procedure

shows a success rate in 98% of the patients. No pneumothorax requiring a chest

tube drainage and no Horner's syndrome were recorded. The most common side

effect was compensatory sweating in 70% of these patients. CONCLUSION: This

procedure is effective, simple, and requires only an overnight study. It is

recommended as the method of choice for surgical treatment of upper extremity

hyperhidrosis.

 

PMID: 8204038 [PubMed - indexed for MEDLINE]

 

 

 

262: J Clin Laser Med Surg  1994 Apr;12(2):93-5

 

Craniofacial hyperhidrosis treated with video endoscopic sympathectomy.

 

Kao MC, Chen YL, Lee YS, Hung CC, Huang SJ.

 

Department of Surgery, Laser Medicine Research Center, National Taiwan

University Taipei, R.O.C.

 

Craniofacial hyperhidrosis as well as palmar hyperhidrosis is an abnormal state

of local excessive sweating of unclear etiology.  The hyperhidrosis may be

isolated in the craniofacial region or associated with palmar hyperhidrosis.

The patient's face is so wet with sweat that their daily activities are often

seriously disturbed.  To the best of our knowledge, there has been no

satisfactory medical therapy, nor any effective surgical treatment reported in

the literature.  In 1991, we started to treat a patient with such distress using

endoscopic ablation of the sympathetic T2 segment, because we mastered the

technique after treating a large series of palmar hyperhidrosis patients.

Furthermore, we were impressed by concomitant reduction of craniofacial sweating

after T2-3 sympathectomy resulting from the relatively different domination of

sympathetic supply between the eye and face.  It appears possible to relieve

excessive sweating of the head and face, without producing ptosis or miosis by

ablation of the T2 segment.  During the past 2 years, 7 patients with severe

craniofacial hyperhidrosis have been successfully treated with the method and

all obtained a satisfactory result.  No complete Horner's syndrome has been

produced except in one patient, who showed a mild and transient left eye ptosis,

in whom coagulation of the sympathetic trunk higher than the T2 segment was

performed. Intraoperative monitoring of forehead skin perfusion and observation

of the change of pupillary size is emphasized during the lesion making.  The

longest postoperative follow-up was 2 years, with a mean follow-up of 12.4

months.(ABSTRACT TRUNCATED AT 250 WORDS)

 

PMID: 10147184 [PubMed - indexed for MEDLINE]

 

 

 

263: Oral Surg Oral Med Oral Pathol  1994 Apr;77(4):317

 

Submandibular gustatory sweating.

 

Haddock A, Porter SR, Scully C, Smith I.

 

Publication Types:

Letter

 

PMID: 8015791 [PubMed - indexed for MEDLINE]

 

 

 

264: Dtsch Med Wochenschr  1994 Mar 4;119(9):321-2

 

[Hyperhidrosis]

 

[Article in German]

 

Nachbar F, Blecher P, Ruzicka T.

 

Dermatologische Klinik und Poliklinik, Universitat, Munchen.

 

PMID: 8119114 [PubMed - indexed for MEDLINE]

 

 

 

265: Acta Anaesthesiol Sin  1994 Mar;32(1):1-6

 

[Alternative one lung ventilation anesthesia for bilateral thoracoscopic

sympathectomy]

 

[Article in Chinese]

 

Ho CS, Kao MC.

 

Department of Anesthesiology, Taiwan Adventist Hospital.

 

Palmar hyperhidrosis (PH) is a common disorder in the oriental subtropical area.

There have been many therapeutic methods, such as: oral medication, local

treatment and traditional surgical operation, but none of them has proved

entirely satisfactory. Since the development of video endoscopic surgery,

transthoracic endoscopic sympathectomy has been increasing day by day. This

study consisted of 124 PH patients under alternative one lung ventilation

anesthesia for bilateral thoracoscopic laser sympathectomy. The age of patients

ranged from 13 to 64 years, male 45 and female 79. The average anesthesia

duration was 60 min. We used glycopyrrolate 0.03 mg/kg, decardon 1 mg/10 kg for

premedication. Induction was with fentanyl 0.07 ml/kg, atracurium 0.6 mg/kg and

thiopental 4 mg/kg. Maintenance was with isoflurane in 3L/min. oxygen

inhalation. The alternative one lung ventilation anesthesia was achieved with

double-lumen endobronchial tube. Fr 37, Fr 35, Fr 28 Sheridan Lt. double-lumen

bronchial tube were used depending upon the sex and fudgement of the individual

patient. All patients tolerated the procedure well so that sympathectomy could

be performed smoothly and uneventfully. Immediately after the operation, a

transient mild to moderate degree of difficult breathing and substernal

discomfort were experienced in the majority of patients. These suffering often

relieved spontaneously or with some common analgesic.

 

PMID: 8199806 [PubMed - indexed for MEDLINE]

 

 

 

266: Acta Anaesthesiol Sin  1994 Mar;32(1):13-20

 

[Experience of anesthesia during transthoracic endoscopic sympathectomy for

palmar hyperhidrosis: comparison between double-lumen endobronchial tube

ventilation and laryngeal mask ventilation]

 

[Article in Japanese]

 

Hsieh YJ, Chen CM, Lin HY, Young TF.

 

Department of Anesthesiology, Provincial Taichung General Hospital.

 

In the past year we had 36 patients operated for transthoracic endoscopic

sympathectomy to treat palmar hyperhidrosis. The first group composed of 17

patients receiving anesthesia with double-lumen endobronchial-tube ventilation

from July-92 to April-93, and the second group composed of 19 patients receiving

anesthesia with laryngeal mask ventilation from April-93 to August-93. During

right lung collapse for sympathectomy, the first group patients' SaO2 (oxygen

saturation) decreased from 99.65 +/- 0.62 mmHg (pre-operation) to 95.12 +/- 5.48

mmHg (at cauterization), 95.24 +/- 5.41 mmHg (5 minutes after cauterization) and

resumed 99.53 +/- 0.62 mmHg after the procedure completed. During left lung

collapse for left side sympathectomy, the same group patients' SaO2 decreased

from 99.59 +/- 0.62 mmHg to 97.35 +/- 3.06 mmHg, 97.82 +/- 2.53 mmHg and resumed

99.65 +/- 0.49 mmHg respectively. The second group using laryngeal mask

ventilation had SaO2 changes during right side sympathectomy from 99.68 +/- 0.58

mmHg (pre-cauterization) to 99.74 +/- 0.45 mmHg (when cauterization), 99.79 +/-

0.42 mmHg (5 minutes after cauterization) and resumed 99.84 +/- 0.37 mmHg after

the procedure completed. During left side sympathectomy the second group

patients' SaO2 changed from 99.84 +/- 0.39 mmHg to 99.42 +/- 1.50 mmHg, 99.47

+/- 1.46 mmHg and resumed 99.74 +/- 0.59 mmHg respectively. After 2-Way ANOVA

with repeated measures of the SaO2 value, we could see that no matter what side

operation, there were differences existed between these two groups (<

0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

 

PMID: 8199807 [PubMed - indexed for MEDLINE]

 

 

 

267: Acta Anaesthesiol Sin  1994 Mar;32(1):57-60

 

Experience of anesthesia for transthoracic endoscopic sympathectomy in palmar

hyperhidrosis--110 cases.

 

Chen YP, Ting MC, Hwang YS, Chow TC, Lin JC.

 

Department of Anesthesiology, Show Chwan Memorial Hospital, Changhua, R.O.C.

 

Transthoracic endoscopic sympathectomy (TES) is an effective treatment for

palmar hyperhidrosis. We review our experience and discuss the anesthetic

technique and perioperative complications encountered in 110 patients undergoing

TES for palmar hyperhidrosis. All patients were monitored with EKG, NIBP and

pulse oximetry (SPO2) during the operation. The trachea was intubated with a

single lumen endotracheal tube and ventilation was controlled manually. 100%

inspired oxygen was necessary during TES to avoid hypoxia. One patient developed

sudden cardiac arrest during electrocauterization of the left sympathetic chain

and two patients required underwater drainage for hemothorax. Minimal

pneumothorax was diagnosed in 4 patients and all cases resolved spontaneously

without active treatment.

 

Publication Types:

Review

Review, Multicase

 

PMID: 8199812 [PubMed - indexed for MEDLINE]

 

 

 

268: Acta Anaesthesiol Sin  1994 Mar;32(1):7-12

 

[Comparison of double-lumen endobnonchial versus single-lumen endotracheal tube

anesthesia in bilateral thoracoscopic sympathectomy]

 

[Article in Chinese]

 

Ho CS, Huang CL.

 

Department of Anesthesiology, Taiwan Adventist Hospital, Taipei, R.O.C.

 

Since the development of video endoscopic surgery, the number of transthoracic

endoscopic sympathectomy has been increasing. The use of double-lumen

endobronchial tube or single-lumen endobronchial tube during anesthesia for

these surgeries has been a controversial. 385 palmar hyperhidrosis patients

divided into three groups: group I, under alterative one lung ventilation

anesthesia with double-lumen endobronchial tube; group II, under alterative one

lung ventilation anesthesia with single-lumen endobronchial tube; group III,

under two lung ventilation anesthesia with single-lumen endobronchial tube were

studied. All had received bilateral thoracoscopic sympathectomy. The age of

patients ranged from 8 to 64 years old. There were 154 male and 231 female. The

average anesthesia durations for group I, II and III were 38.56 +/- 10.28, 34.14

+/- 5.21, 31.83 +/- 3.34 min respectively. The variables considered in the study

were: physique of the patients; duration of anesthesia; airway pressure changes;

SaO2 changes during the operation and post-anesthesia complaints. We found that

upon using double-lumen endobronchial tube, SaO2 levels was better maintained

especially in the obese patients and the patients who had received a traditional

surgical operation before.

 

PMID: 8199816 [PubMed - indexed for MEDLINE]

 

 

 

269: Arch Surg  1994 Mar;129(3):241-4

 

Endoscopic transthoracic sympathectomy in the treatment of primary

hyperhidrosis. A review of 290 sympathectomies.

 

Shachor D, Jedeikin R, Olsfanger D, Bendahan J, Sivak G, Freund U.

 

Department of Surgery, Meir Hospital, Kfar Saba, Israel.

 

OBJECTIVES: To describe the surgical technique of endoscopic transthoracic

sympathectomy for the treatment of palmar hyperhidrosis and to identify

associated complications. DESIGN: Prospective clinical study. SETTING:

University referral center. PATIENTS: A consecutive series of 150 patients with

primary palmar hyperhidrosis. INTERVENTION: The surgical procedure is performed

under general anesthesia. A trocar and endoscope are inserted into the chest

cavity. The sympathetic chain and the second, third, and fourth ganglia are then

identified, cauterized, and cut. After reinflation of the lung, the procedure is

repeated on the other side. RESULTS: Two hundred ninety sympathectomies were

performed with a 98% success rate. Complications of the procedure included

pneumothorax in seven patients (2.4%), hemothorax in three (1.0%), and temporary

Horner's syndrome in two (0.7%). Severe postoperative pain during the first 2 to

4 hours required treatment. Of 60 patients who were followed up for 12 months,

50% developed compensatory sweating and 8.3% developed rebound sweating.

Hyperhidrosis recurred in three patients. CONCLUSION: Endoscopic transthoracic

sympathectomy is an effective form of treatment for palmar primary

hyperhidrosis, is associated with a low morbidity, and can be performed as an

ambulatory procedure.

 

Publication Types:

Clinical Trial

 

PMID: 8129596 [PubMed - indexed for MEDLINE]

 

 

 

270: Eur J Vasc Surg  1994 Mar;8(2):129-37

 

The role of sympathectomy in current surgical practice.

 

Gordon A, Zechmeister K, Collin J.

 

University of Oxford, Nuffield Department of Surgery, John Radcliffe Hospital,

U.K.

 

Historically sympathectomy has been employed in the treatment of a variety of

disparate disorders but in most there is little if any objective clinical

evidence of its efficacy. Review of the literature confirms that sympathectomy

provides an effective and permanent cure for hyperhidrosis of the hands and

feet, and at present palmar hyperhidrosis is the major indication for its

regular use. Sympathetic denervation of the hands is currently most easily

achieved with minimal morbidity by thoracoscopic ablation of the second thoracic

ganglion. Some evidence testifies to the efficacy of sympathectomy in the rare

patients with true major causalgia. Clinical experience suggests that Raynaud's

phenomenon in the feet can be usefully ameliorated by sympathectomy but in the

hands any benefit is short lived and there is no effect on the prognosis of the

disease. A weak case can be made for sympathectomy for ischaemic rest pain when

arterial surgery is impractical but there is no reliable evidence to support its

use in Buerger's disease, intermittent claudication, diabetic vascular disease

or ischaemic ulceration or gangrene.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 8181604 [PubMed - indexed for MEDLINE]

 

 

 

271: J Pediatr Surg  1994 Mar;29(3):382-6

 

Transaxillary upper thoracic sympathectomy for primary palmar hyperhidrosis in

children and adolescents.

 

Mares AJ, Steiner Z, Cohen Z, Finaly R, Freud E, Mordehai J.

 

Department of Pediatric Surgery, Soroka Medical Center, Faculty of Health

Sciences, Ben-Gurion University of the Negev, Beer-Sheba, Israel.

 

Primary palmar hyperhidrosis is part of a triad of palmar, plantar, and axillary

hyperhidrosis of unknown etiology, affecting children, adolescents, and young

adults. Sixty-seven children and young adolescents were operated on during a

10-year period. A total of 103 transaxillary upper thoracic sympathectomies (36

bilateral) were performed, with no mortality. The immediate postoperative course

was uneventful in 90%; the other 10% had mostly minor problems. The average

hospitalization period was 3 to 4 days. Total abolition of palmar sweating was

achieved in all but two patients in whom some residual moisture remained.

Long-term extreme satisfaction was reported by 64 of 67 patients (94%). One was

moderately satisfied, and two were not satisfied because of excessive

"compensatory" sweating elsewhere. Compensatory sweating of some degree was

reported by 45% of patients but did not alter satisfaction. By further limiting

ganglionectomy to just one ganglion (T2 or T3), compensatory sweating possibly

may be reduced further. Early surgery for severe palmar hyperhidrosis will save

a child many years of agony and social discomfort because all types of

conservative therapy are ineffective and cause unnecessary delay. A limited

transaxillary upper thoracic sympathectomy is presently the authors' preferred

approach, although ablation via thoracoscopy should not be excluded as further

experience is gained with this modality.

 

PMID: 8201503 [PubMed - indexed for MEDLINE]

 

 

 

272: J Pediatr Surg  1994 Mar;29(3):387-91

 

Palmar hyperhidrosis in children: treatment with video endoscopic laser

sympathectomy.

 

Kao MC, Lee WY, Yip KM, Hsiao YY, Lee YS, Tsai JC.

 

Department of Surgery, College of Medicine, National Taiwan University, Taipei,

Republic of China.

 

Palmar hyperhidrosis (PH) often starts in childhood and can be a disabling

condition for a significant number of young children at the age they begin

primary school. There are few reports regarding the surgical treatment of PH in

children. The authors report on 40 PH patients under 16 years of age treated

with video thoracoscopic laser sympathectomy; there has been substantial

experience with this procedure for the treatment of adults with PH. A

satisfactory result, with very low morbidity, was achieved for all 40 children.

The surgical technique is described briefly. With the technique, the proper

sympathetic segment is visualized in almost all cases and then definitely

ablated with a fiberoptic low-power laser while under the aid of sympathetic

monitoring. Consequently, an adequate sympathectomy warranting a long-lasting

therapeutic effect can be achieved without the need of tissue diagnosis. No case

required conversion to open sympathectomy. Neither injury to the lung nor

bleeding was encountered. Horner's syndrome did not occur in any case. Bilateral

sympathectomy was accomplished generally within 30 minutes. All patients were

discharged after an overnight stay and are doing well with normal activities.

The most frequent complication was compensatory hyperhidrosis, which was

tolerable after reassurance. Based on the accumulated experience, it is

justified to recommend early surgery, with this refined technique, in cases of

severe PH in children.

 

PMID: 8201504 [PubMed - indexed for MEDLINE]

 

 

 

273: Cardiovasc Surg  1994 Feb;2(1):9-15

 

Sympathectomy: quo vadis?

 

Barnes RW.

 

Department of Surgery, University of Arkansas for Medical Sciences, Little Rock.

 

This paper reviews the evolution of sympathectomy in the management of vascular

disease, hyperhidrosis and reflex sympathetic dystrophy over the past 26 years.

The average general surgery resident has never been exposed to the procedure.

The author feels that sympathectomy should be part of the armamentarium of

vascular surgeons. An understanding of physiologic screening tests is necessary

for the proper selection of patients who may benefit from sympathectomy. There

has been a progressive decline in the number of publications on sympathectomy

during this period. While the procedure is less commonly performed for vascular

disease, sympathectomy remains a useful treatment for uncontrolled hyperhidrosis

and for reflex sympathetic dystrophy.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 8049934 [PubMed - indexed for MEDLINE]

 

 

 

274: Eur J Pediatr Surg  1994 Feb;4(1):3-6

 

Trans-axillary transpleural sympathectomy for Palmar hyperhidrosis in

children--a 3 to 7 year follow-up of 9 cases.

 

Millar AJ, Steiner Z, Rode H, Cywes S.

 

Department of Paediatric Surgery, University of Cape Town, South Africa.

 

Primary palmar hyperhidrosis can be a most unpleasant and distressing

affliction. When normal daily activities, viz. writing, schoolwork, are

interfered with and other treatments have failed, surgery is indicated. Between

1983-1987 9 children (6 F, 3 M), mean age 10.2 years (range 5-14 years)

underwent bilateral transaxillary sympathectomy, 4 simultaneous and 5 1-4 weeks

apart. On 14 sides a standard excision of dorsal ganglia (DG) 2, 3, and 4 was

performed. The technique of lateral displacement of the sympathetic chain after

transection distal to DG 4 and division of preganglionic fibres of DG 4, 3 and 2

was used on 5 sides. In addition to clinical evaluation a pilocarpine

stimulation test was performed on the palms of the hands before and at follow-up

3-7 years after surgery. 17/18 hands appeared sympathectomised at early

follow-up. One inadequate result required reoperation. Other complications

included 2 Horner's syndromes--1 transient and 1 mild but permanent; 3 temporary

intercostobrachial paraesthesias, 2 mild late recurrences of sweating and 2

compensatory increases in sweating. In 14 palms where sweat volume was measured

before and 3-7 years after surgery there was a mean decrease in sweat of 84%

(mg), those sweating the most prior to surgery having the best response. In 2

further palms insufficient sweat was obtained for testing. All but 1 considered

the procedure worthwhile. Transaxillary transpleural sympathectomy is a safe,

effective, and cosmetically acceptable operation to control symptoms of

excessive palmar sweating.(ABSTRACT TRUNCATED AT 250 WORDS)

 

PMID: 8199129 [PubMed - indexed for MEDLINE]

 

 

 

275: Neurosurgery  1994 Feb;34(2):262-8; discussion 268

 

Comment in:

 Neurosurgery. 2001 Mar;48(3):702.

 

Autonomic activities in hyperhidrosis patients before, during, and after

endoscopic laser sympathectomy.

 

Kao MC, Tsai JC, Lai DM, Hsiao YY, Lee YS, Chiu MJ.

 

Department of Surgery, National Taiwan University, Taipei, Republic of China.

 

Three hundred palmar hyperhidrosis (PH) patients have been treated with video

endoscopic laser sympathectomy during the last 2 years. Monitoring the palmar

skin perfusion (PSP) and palmar skin temperature (PST) has been used

intraoperatively to aid the confirmation of the correct sympathetic segment for

laser ablation. The preoperative and postoperative PSP and PST and sympathetic

skin response (SSR) also have been measured to evaluate the therapeutic effect

of this method. An apparent increase of PSP would occur intraoperatively after

the interruption of the T2 sympathetic segment, and then a gradual elevation of

PST would follow after the extirpation of the segment. A rise of PST of about 3

degrees C after laser ablation of the appropriate segment indicated sufficient

denervation of the hand and predicted long-lasting relief of PH. Furthermore,

both PSP and PST also significantly increased after the operation. The

postoperative elevation of the PST (usually about 3 degrees C) is similar to

that recorded during intraoperative monitoring. The amplitude and the latency of

SSR in the palm and sole were recorded both before and after sympathectomy. A

remarkable decrease of palmar SSR amplitude and its ratio was found

postoperatively by comparing it with that of plantar SSR in the same patient.

These autonomic activity changes have correlated well with the postoperative

satisfaction of the patients. Based on our study, the anatomic identification

confirmed by the sympathetic monitorings has proved essential to achieve a

definite and adequate sympathectomy leading to a satisfactory resolution of PH

without the need of a tissue diagnosis.(ABSTRACT TRUNCATED AT 250 WORDS)

 

PMID: 8177387 [PubMed - indexed for MEDLINE]

 

 

 

276: Lancet  1994 Jan 29;343(8892):247-8

 

Hyperhidrosis.

 

Claes G, Drott C.

 

Department of Surgery, Boras Hospital, Sweden.

 

PMID: 7905089 [PubMed - indexed for MEDLINE]

 

 

 

277: Ann Acad Med Singapore  1994 Jan;23(1):38-42

 

Video thoracoscopic laser sympathectomy for palmar hyperhidrosis.

 

Kao MC, Chern SH, Cheng LC, Hsiao YY, Lee YS, Tsai JC.

 

Department of Surgery, College of Medicine, National Taiwan University, Taipei,

ROC.

 

Palmar hyperhidrosis (PH) is common in Orientals from subtropical areas. Many

therapeutic modalities are used in practice, but none has proved to be entirely

satisfactory. We have developed a new therapeutic technique by combining a video

thoracoscopic system with a surgical laser unit (both waveguide CO2 laser and

fibre-optic Nd:YAG laser). The operation was performed under general anaesthesia

with alternative one-lung ventilation. With this technique, we are able to

identify the sympathetic trunk on the TV screen and confirm its proper level

with accurate ablation by intraoperative vasomotor monitoring. Consequently, an

adequate sympathectomy can be definitely achieved through laser extirpation. We

have successfully treated 300 PH patients with this technique from 1990 to 1992.

The ages ranged from six to 63 years with a mean of 26.6. There were 125 males

and 175 females. Most patients underwent en bloc ablation of the T2 segment

which includes a major part of the T2 ganglion with its adjacent trunk which

overlays the T2 rib head. All of them obtained a satisfactory relief of PH

except 13 patients. The procedure did not result in a change of vital signs.

There was neither obvious injury to lung nor bleeding. No Horner's syndrome was

produced. The commonest complication was compensatory hyperhidrosis in various

degrees encountered in about half of the cases. Two-thirds of the patients were

followed up for more than 12 months and only three had recurrence. Based on our

experience, the technique is considered to be a minor and safe procedure and

able to achieve a definite and long-lasting therapeutic effect. It causes

minimal discomfort and scarring. Particularly, the operation time and hospital

stay were markedly shortened in comparison with other conventional open

sympathectomy procedures.

 

PMID: 8185269 [PubMed - indexed for MEDLINE]

 

 

 

278: Eur J Surg Suppl  1994;(572):51-3

 

Thoracoscopic sympathicotomy for hyperhidrosis--surgical technique,

complications and side effects.

 

Gothberg G, Drott C, Claes G.

 

Department of Pediatric Surgery, East Hospital Goteborg, Sweden.

 

Thoracic sympathectomy is a very effective treatment of palmar hyperhidrosis.

The described endoscopic technique has given good primary results in 99% of

patients. After another session with this type of "minimal invasive surgery"

100% of the hands were satisfactorily dry. The hospital stay is just one

post-operative day and the sick-leave is about a week. The drawbacks are

minimal. Pain is tolerable and only eight patients needed a post-operative

Bulau-drainage because of pneumothorax or bleeding. About 50% of patients

experience a compensatory increased sweating of the trunk, but this is related

to a warm environment and regulation of body temperature and seems to decrease

with time. This technique makes it possible to treat all those suffering from

palmar hyperhidrosis which can be a substantial, but underestimated handicap. To

meet this kind of patient after a successful operation is extremely satisfying

even for the surgeon. The post-operative wet and cold hand has immediately

post-operatively become warm and dry.

 

PMID: 7524785 [PubMed - indexed for MEDLINE]

 

 

 

279: Eur J Surg Suppl  1994;(572):5-7

 

The history of cervicothoracic sympathectomy.

 

Drott C.

 

Department of Surgery, Boras Hospital, Sweden.

 

As early as in 1889 surgery on the cervical sympathetic nervous system was

performed. During the following decades this operation was tried for a variety

of diseases. In the early 1920s it was clarified that patients with

hyperhidrosis, vasospastic conditions, and angina pectoris would benefit from

stellectomy. It was, however, soon discovered that removal of the upper thoracic

ganglia was required in order to obtain complete sympathetic denervation of the

upper extremity. Several open surgical techniques for upper thoracic

sympathectomy were described. During the 1940s a few pioneers started to excise

sympathetic ganglia by thoracoscopy which had originally been described as a

diagnostic tool by Jacobaeus in 1910. The endoscopic approach, amply documented

by Kux in 1954, did not, however, gain widespread popularity until the 1980s.

Like the general upsurge of interest in endoscopic surgery, thoracoscopic

ablation of the upper thoracic sympathetic ganglia is now rapidly being adopted

by surgeons.

 

Publication Types:

Historical Article

 

PMID: 7524784 [PubMed - indexed for MEDLINE]

 

 

 

280: Eur J Surg Suppl  1994;(572):43-5

 

Intraoperative cardiac arrest: a rare complication of T2,3-sympathicotomy for

treatment of hyperhidrosis palmaris. Two case reports.

 

Lin CC, Mo LR, Hwang MH.

 

Surgical Department, Tainan Municipal Hospital, Taiwan.

 

Endoscopic surgery, including thoracoscopic sympathicotomy for treatment of

hyperhidrosis, is thought to be safe and entail fewer complications as compared

with open methods. A total of more than 719 patients with hyperhidrosis have

undergone thoracoscopic T2,3-sympathicotomy for treatment of hyperhidrosis at

Tainan Municipal Hospital since October 1, 1989. Most of the complications have

been minor; however, two of the patients suffered from sudden cardiac arrest at

the time when the left T2,3-sympathetic nerve trunk was transected by the

thoracoscopic method. Vigorous cardiopulmonary resuscitation was performed and

both patients recovered completely without any sequelae. The purpose of this

paper was to discuss the possible mechanism of cardiac arrest in thoracoscopic

sympathicotomy, and to emphasise this rare but potentially fatal complication in

the treatment of hyperhidrosis palmaris.

 

PMID: 7524782 [PubMed - indexed for MEDLINE]

 

 

 

281: Eur J Surg Suppl  1994;(572):65-70

 

Cardiac effects of endoscopic electrocautery of the upper thoracic sympathetic

chain.

 

Drott C, Claes G, Gothberg G, Paszkowski P.

 

Department of Surgery, Boraas Hospital, Sweden.

 

Bilateral endoscopic electrocautery of the upper thoracic sympathetic ganglia

(T2-4) was performed, mainly for palmar hyperhidrosis, on 535 patients. The aim

of this study was to evaluate the effects of this procedure on cardiac and

physical performance. A subgroup of 18 patients underwent cycle ergometer test

with ECG recordings before and three months after surgery. After the operation,

a significantly reduced heart rate at rest (12%) as well as during exercise and

during recovery after exercise was found. The systolic blood pressure was

reduced only at rest (7%) and the diastolic blood pressure was not significantly

altered. Maximal workload was not affected by the operation and only a few

patients had noticed their reduced heart rate. Three patients with angina

pectoris and three with incapacitating tachycardia related to mental stress were

operated on with excellent results. Thoracoscopic sympathicotomy is a safe,

fast, cheap and efficient method for cardiac sympathetic denervation. This

procedure might constitute an alternative to long-term thoracic epidural

anaesthesia and implantation of thoracic electric stimulation devices in

patients not suited for aortocoronary by-pass. Patients who require cardiac

beta-receptor blockers and suffer from side effects of these drugs might also

benefit from surgical cardiac sympathetic denervation.

 

PMID: 7524789 [PubMed - indexed for MEDLINE]

 

 

 

282: Eur J Surg Suppl  1994;(572):27-31

 

Single-lumen endotracheal intubated anaesthesia for thoracoscopic

sympathectomy--experience of 719 cases.

 

Lee LS, Ng SM, Lin CC.

 

Department of Anaesthesia, Tainan Municipal Hospital, Taiwan, Republic of China.

 

A total of 719 thoracoscopic sympathicotomies were performed at our hospital

from October, 1989 to December, 1992. We have been practicing single-lumen

endotracheal intubation for general anaesthesia in all of our cases. We will

review our experience and discuss our anaesthetic technique and the

intraoperative complications encountered as well as post-operative pain control.

General anaesthesia with controlled manual ventilation assisted the surgeon well

and created clear access for electro-cauterisation of the sympathetic chain.

Thirty patients were randomly chosen for arterial blood gas analysis. There was

no evidence of systemic hypoxaemia or clinically significant carbon dioxide

retention throughout the surgery or afterwards in the recovery room. In our

experience of 719 cases, single-lumen endotracheal intubated anaesthesia is safe

and economic for thoracoscopic sympathicotomy.

 

PMID: 7524778 [PubMed - indexed for MEDLINE]

 

 

 

283: Eur J Surg Suppl  1994;(572):23-5

 

Intraoperative anaesthetic management of hypoxaemia during transthoracic

endoscopic sympathectomy.

 

Jedeikin R, Olsfanger D, Shachor D.

 

Department of Anaesthesia and Intensive Care, Sackler School of Medicine,

University of Tel Aviv, Meir Hospital, Kfar Saba, Israel.

 

OBJECTIVE: To present our experience and evaluate intraoperative arterial oxygen

desaturation during anaesthesia for transthoracic endoscopic sympathectomy

(TES). DESIGN: Prospective open study. SETTING: University Hospital in Israel.

SUBJECTS: Consecutive series of patients (n = 210), suffering from upper limb

hyperhidrosis, anaesthetised for TES. MAIN OUTCOME MEASURES: Peripheral oxygen

saturation (SpO2), haemodynamic status, complications, postoperative pain (n =

210) and arterial blood gases (n = 10). RESULTS: 407 TES; 195 bilateral, 17

unilateral. Surgical time range 20-75 minutes. SpO2 decreased below 98% in 58

patients. Sudden hypotension and bradycardia in two patients. The mean PaO2 was

significantly (p = 0.03) decreased during two-lung ventilation (TLV), after

reinflation of the right lung, compared with TLV after endobronchial intubation.

There was no significant difference in mean PaO2 during one-lung ventilation of

both lungs. Lowest PaO2 observed during one-lung ventilation was less than 13.3

kPa in three sympathectomies. Postoperative pain, severe on awakening and mainly

retrosternal, was relieved with i.v. opiates. CONCLUSION: Controlled ventilation

with 100% inspired O2, SpO2 monitoring and one to two gentle manual ventilations

when it decreases is the cornerstone of the management of hypoxaemia, a

potentially serious complication of TES.

 

PMID: 7524777 [PubMed - indexed for MEDLINE]

 

 

 

284: Eur J Surg Suppl  1994;(572):21

 

Thoracoscopic surgery of palmar hyperhidrosis.

 

Svartholm E, Asking B.

 

Department of Surgery, Regional Hospital Ryhov, Jonkoping, Sweden.

 

New thoracoscopic methods have been reported to minimise the operative trauma

after surgical treatment of primary hyperhidrosis of the palms. We therefore

began with this minimally invasive technique for sympathetic ablation in 1990.

Our first 81 patients presented here confirm earlier results of excellent

effects, few complications and mild side-effects when treating palmar

hyperhidrosis with thoracoscopic sympathectomy.

 

PMID: 7524776 [PubMed - indexed for MEDLINE]

 

 

 

285: Eur J Surg Suppl  1994;(572):17-9

 

Present and future trends in thoracoscopic sympathectomy.

 

Hederman WP.

 

Mater Misericordiae Hospital, Dublin, Ireland.

 

PMID: 7524775 [PubMed - indexed for MEDLINE]

 

 

 

286: Eur J Surg Suppl  1994;(572):13-6

 

Thoracoscopic versus open supraclavicular upper dorsal sympathectomy: a

prospective randomised trial.

 

Hashmonai M, Kopelman D, Schein M.

 

Department of Surgery B, Rambam Medical Centre, Haifa, Israel.

 

The purpose of the present study was to compare the short term results of the

"open" supraclavicular approach with the thoracoscopic access for T2-T4

sympathetic ganglionectomy in patients with palmar hyperhidrosis. Patients were

randomly allocated into two groups of 12 each, and were operated on: one by the

open supraclavicular access; the other by the transthoracoscopic approach. The

effect on palmar perspiration, operative data, postoperative complications and

patients's satisfaction on short term follow up were examined. All operations

achieved dry hands. Only two significant differences were observed: longer

anaesthesia and poorer patient satisfaction in the thoracoscopic group one week

after surgery (probably because a higher proportion of cases developed prolonged

postoperative chest pain). Both techniques similarly achieve dry hands. The open

method is not longer or more difficult, is possibly associated with less

morbidity, and gives a higher subjective satisfaction.

 

Publication Types:

Clinical Trial

Randomized Controlled Trial

 

PMID: 7524774 [PubMed - indexed for MEDLINE]

 

 

 

287: Eur J Surg Suppl  1994;(572):9-11

 

Surgical treatment of palmar hyperhidrosis before thoracoscopy: experience with

475 patients.

 

Adar R.

 

Department of General and Vascular Surgery, Sheba Medical Center, Tel Hashomer,

Israel.

 

Between the years 1968-1992, 475 patients underwent simultaneous bilateral upper

dorsal sympathectomy by the supraclavicular approach for severe palmar

hyperhidrosis. For the purpose of comparing outcomes of the open surgical method

with the increasingly used thoracoscopic procedure, we reviewed the clinical

data of our patients. The incidence of severe palmar hyperhidrosis in the young

population in Israel is 1-2/1,000. Surgical excision of the T2 and T3 ganglia

was effective in drying the hands of all patients, who had frozen section

confirmation of removal of a ganglion. At follow-up, hyperhidrosis recurred in

5.3% of limbs. Mild transient Horner's syndrome occurred in 12% of procedures,

but only in 5 patients was it permanent. The main drawback of the open surgical

approach lies in the postoperative complications. The effectiveness of the

thoracoscopic approach will be judged by immediate and late results, and by the

expected reduction in postoperative morbidity.

 

PMID: 7524790 [PubMed - indexed for MEDLINE]

 

 

 

288: Eur J Surg Suppl  1994;(572):41-2

 

Degeneration activity: a transient effect following sympathectomy for

hyperhidrosis.

 

Asking B, Svartholm E.

 

Department of Surgery, Jonkoping Hospital, Sweden.

 

The degeneration activity of effector organs is due to a period of transmitter

release from degenerating sympathetic post-ganglionic nerve endings. This is the

theoretical explanation for a period of sweating some days following

sympathectomy for hyperhidrosis seen in some patients operated on with the

thoracoscopic technique in Jonkoping, Sweden. The reasons for degeneration

activity, well documented in animal experiments, are discussed in this paper.

 

PMID: 7524781 [PubMed - indexed for MEDLINE]

 

 

 

289: Eur J Surg Suppl  1994;(572):37-9

 

Total intravenous anaesthesia with single-lumen endotracheal intubation for

thoracoscopic sympathectomy.

 

Harlid R.

 

Department of Anaesthesia and Intensive Care, Boras Hospital, Sweden.

 

The aim of this paper was to discuss the stress applied to the circulatory and

respiratory systems by the combination of general anaesthesia and thoracoscopic

sympathectomy and to show the benefits of an intravenous anaesthetic technique

together with a single-lumen endotracheal tube as a safe method of anaesthesia

for this procedure. In a retrospective study, 125 cases of thoracoscopic

sympathectomy were reviewed. The anaesthesia was a totally intravenous technique

with propofol, alfentanil, and atracurium and a gas mixture of 40% oxygen in

air. The degree of hypoxaemia during inflation of carbon dioxide into the thorax

was assessed. The results showed that hypoxaemia caused no problems in any of

the patients. Three patients with severe angina pectoris were also studied using

the same anaesthetic technique and they showed marked haemodynamic instability

throughout the procedure requiring inotropic support. Haemodynamic values

obtained through a Swan-Ganz catheter in one patient showed marked changes

during the procedure, but values returned to normal after the operation.

Although these patients were haemodynamically unstable there was no problem with

hypoxaemia.

 

PMID: 7524780 [PubMed - indexed for MEDLINE]

 

 

 

290: Eur J Surg Suppl  1994;(572):33-6

 

Anaesthetic implications for transthoracic endoscopic sympathectomy.

 

Hartrey R, Poskitt KR, Heather BP, Durkin MA.

 

Department of Anaesthesia, Cheltenham General Hospital, England.

 

Transthoracic endoscopic sympathectomy is now considered the treatment of choice

for patients with upper limb hyperhidrosis requiring sympathetic ablation. This

procedure requires the use of an endobronchial double lumen tube and subsequent

one-lung anaesthesia, a technique that is associated with a number of potential

problems. Full patient monitoring is thus required and includes pulse, ECG,

non-invasive blood pressure measurement, pulse oximetry, end-tidal carbon

dioxide concentration and peak inspiratory airway pressure. We reviewed our

anaesthetic technique and peri-operative complications in 26 patients, to assess

patient safety. In our study hypoxaemia occurred commonly but was transient in

all bar one case where re-expansion of the lung was required. Hypotension

occurred at two stages of the procedure, but active intervention was not

required, and two patients required underwater drainage of the pleural cavity

for treatment of pneumothorax. With skilled anaesthetic personnel and adequate

monitoring this procedure may be carried out safely.

 

PMID: 7524779 [PubMed - indexed for MEDLINE]

 

 

 

291: Stereotact Funct Neurosurg  1994;63(1-4):198-202

 

Thoracoscopic ganglionectomy for hyperhidrosis.

 

Pillay PK, Thomas J, Mack P.

 

Department of Neurosurgery, Singapore General Hospital.

 

Thoracoscopic sympathectomy for the treatment of hyperhidrosis has been carried

out with techniques that involve either monopolar coagulation or laser injury to

the T2 ganglion. Although this has the advantage of being minimally invasive, it

has not been established whether these techniques are superior to complete

ganglion excision, as carried out during open surgery. A new technique of

complete T2 ganglion excision for palmar hyperhidrosis (with T3 ganglionectomy

for axillary sweating) was developed using thoracoscopic techniques. Sixteen

patients were treated with thoracoscopic T2 ganglion excision on the right side,

and simple coagulation (Nd-YAG laser or monopolar) on the left side. Results

were excellent with no posttreatment differences between hands at 1 year

follow-up. However, long-term follow-up of these patients will be carried out to

determine whether differences exist between these two techniques.

 

PMID: 7624635 [PubMed - indexed for MEDLINE]

 

 

 

292: Dtsch Med Wochenschr  1993 Dec 23;118(51-52):1910

 

[Palmoplantar hyperhidrosis]

 

[Article in German]

 

Lamminger C, Petzoldt D.

 

Abteilung Dermatologie I mit Poliklinik der Universitats-Hautklinik, Heidelberg.

 

PMID: 8287784 [PubMed - indexed for MEDLINE]

 

 

 

293: Clin Pediatr (Phila)  1993 Oct;32(10):629-31

 

Gustatory flushing syndrome. A pediatric case report and review of the

literature.

 

Kozma C, Gabriel S.

 

Department of Pediatrics, Georgetown University Medical Center, Washington, D.C.

20007.

 

Publication Types:

Review

Review of Reported Cases

 

PMID: 8261729 [PubMed - indexed for MEDLINE]

 

 

 

294: Endosc Surg Allied Technol  1993 Oct-Dec;1(5-6):261-5

 

Thoracoscopic sympathectomy.

 

Byrne J, Walsh TN, Hederman WP.

 

Dept. of Surgery, Liandough Hospital, Cardiff, Wales.

 

Surgical sympathectomy has traditionally been achieved by 'open' surgical

techniques. The transaxillary, cervical, or dorsal approaches have not been

without morbidity and cosmetically have been found to be less than ideal. The

main indication for sympathectomy in most units is palmar and axillary

hyperhidrosis refractory to medical treatment, although it has been used with

some success in troublesome causalgia. Use of sympathectomy in Raynaud's disease

remains disappointing. In our unit thoracoscopic sympathectomy has been

performed since 1980. A CO2 pneumothorax is initially created in the usual

manner. This is followed by electrocoagulation of the sympathetic chain under

direct vision using a unipolar diathermy. The lung is then reinflated under

direct vision. Chest drains are not inserted. Both sides are performed at the

same sitting, and the patient usually leaves hospital the following day. The

functional and cosmetic results are excellent on short and long term follow-up

with few side effects. Permanent Horner's syndrome has not been reported using

this technique. As with all upper limb sympathectomies, patients should be

warned of possible compensatory hyperhidrosis. Embracing the tenets of minimally

invasive surgery, thoracoscopic sympathectomy should be considered the approach

of choice for surgical sympathectomy.

 

PMID: 8081893 [PubMed - indexed for MEDLINE]

 

 

 

295: Surg Laparosc Endosc  1993 Oct;3(5):365-9

 

Transaxillary endoscopic sympathectomy--a report of experience in 150 patients

with palmar hyperhidrosis.

 

Chao C, Tsai CT, Hsiao HC, Wu WC, Lee CK.

 

Department of Surgery, Naval General Hospital, Kaohsiung, Taiwan, R.O.C.

 

We report our 1-year experience with transaxillary endoscopic sympathectomy in

150 patients with palmar hyperhidrosis (PH). The double-puncture technique of

video laparoscopy was used in a transaxillary approach to perform the

sympathectomy by either electrocautery (EC; 93.3%) or electroresection (ER;

7.7%). The procedure was successfully completed in 299 operated limbs and

required conversion to open surgery in 1 operated limb because of extensive

pleural adhesions. The mean operative time of EC was significantly less than

that of ER. In a total of 29 procedures, there were three technical

complications. Most patients (92.7%) were discharged after an overnight hospital

stay. On the seventh postoperative day, the cure rate was 99.3%. During the mean

follow-up period of 200.1 days, there was no recurrence in 130 patients.

Apparent compensatory hyperhidrosis occurred in 28 patients (21.5%). In

conclusion, transaxillary endoscopic sympathectomy offers a simple and effective

treatment to patients with PH, resulting in a shorter hospital stay and

convalescent period.

 

PMID: 8261263 [PubMed - indexed for MEDLINE]

 

 

 

296: Surg Laparosc Endosc  1993 Oct;3(5):391-4

 

Thoracoscopic sympathectomy.

 

Krasna MJ, Flowers J, Morvick R.

 

Department of Surgery, University of Maryland School of Medicine, Baltimore

21201.

 

With the advent of advanced video and laparoscopic techniques, new applications

have been found for thoracoscopy's expanding role in thoracic surgery. Described

herein are three cases of thoracoscopic sympathectomy for three different

indications. The evaluation and surgical technique are described in detail.

Thoracoscopic sympathectomy is an excellent alternative to open transthoracic

approach.

 

PMID: 8261268 [PubMed - indexed for MEDLINE]

 

 

 

297: Ann Thorac Surg  1993 Sep;56(3):715-6

 

Thoracoscopy for autonomic disorders.

 

Claes G, Drott C, Gothberg G.

 

Department of Surgery, Boras Hospital, Sweden.

 

Sympathetic denervation of the arm, the hand, and the heart may now be performed

using minimal thoracoscopic procedures. During a 5-year period more than 500

patients were operated on with no major and only a few minor complications. An

operation time of 25 minutes, a hospital stay of 1 day, and sick leave of less

than 1 week have made the operation suitable for autonomous disorders such as

hyperhidrosis. Other conditions such as causalgia, vascular insufficiency, and

angina pectoris may be improved or disappear after sympathectomy, but the

recurrence rate in Raynaud's disease is high.

 

PMID: 8379778 [PubMed - indexed for MEDLINE]

 

 

 

298: Br J Theatre Nurs  1993 Aug;3(5):17-9

 

How recovery helped me to recover. Experiences of hyperhydrosis.

 

Sumner J.

 

PMID: 8400531 [PubMed - indexed for MEDLINE]

 

 

 

299: J Neurosurg  1993 Aug;79(2):238-40

 

Video-assisted endoscopic thoracic ganglionectomy.

 

Robertson DP, Simpson RK, Rose JE, Garza JS.

 

Department of Neurosurgery, Baylor College of Medicine, Houston, Texas.

 

Sympathetic nerve disorders of the upper extremities can be treated by

neurosurgeons using upper thoracic sympathectomy via a posterior approach.

Descriptions have been published of alternative endoscopic procedures involving

thermocoagulation, laser coagulation, or nonvideo-assisted ganglionectomy using

equipment not widely available, with low morbidity and excellent results. The

authors describe the use of an endoscopic approach to the thoracic sympathetic

ganglia with systems designed for laparoscopic cholecystectomy. Thoracic

ganglionectomy is reported in 22 patients with primary palmar hyperhidrosis and

eight patients with reflex sympathetic dystrophy. The patients underwent

double-lumen endotracheal intubation, after which 11- and 5.5-mm trocars were

introduced into the chest cavity. Pneumothorax was produced with CO2

insufflation. Fiberoptic closed-circuit television was used to visualize the

structures to be dissected. The parietal pleura over the heads of the first and

second ribs was excised using 5-mm blunt and sharp insulated coagulating

microscissors. The stellate and upper thoracic ganglia were clearly identified

and dissected. The T-2 and T-3 ganglia were grasped with forceps and excised. A

No. 16 French chest tube was introduced through a trocar, placed under water

seal after the lungs were reinflated, and removed in the recovery room. The

average hospital stay was 15.4 hours. There were no intraoperative

complications. The average operating time was 30 minutes per side. Five patients

had mild pleuritic pain which resolved within 2 weeks after surgery. Six (75%)

of the eight patients with reflex sympathetic dystrophy had complete or partial

relief of their symptoms (average follow-up period 5 months), and all patients

had complete relief of hyperhidrosis (average follow-up period 8 months).

Endoscopic ganglionectomy requires readily available and easily used

instrumentation and provides a well-tolerated, cost-effective alternative to

posterior thoracic sympathectomy for primary palmar hyperhidrosis and reflex

sympathetic dystrophy.

 

PMID: 8331407 [PubMed - indexed for MEDLINE]

 

 

 

300: Thorac Cardiovasc Surg  1993 Aug;41(4):245-8

 

Selective video-assisted thoracoscopic sympathectomy.

 

Friedel G, Linder A, Toomes H.

 

Schillerhohe Hospital, Center for Pneumology and Thoracic Surgery, Gerlingen,

Germany.

 

Video-assisted and thermometrically controlled thoracoscopic sympathectomy

demonstrates new ways in the treatment of upper-limb hyperhidrosis. An

anatomical portrayal of the sympathetic chain is possible as a result of the

improved visualization and magnification of the operative area provided by the

video-optic technique. The difference in temperature, registered by means of a

thermometric sensor in the palm of the hand, indicates that the sympathetic

nerves responsible for the hyperhidrotic segments have been severed. The number

of postoperative Horner's syndromes will be reduced significantly with this

method. Until now, we have successfully treated six thermometrically controlled

patients. No recurrences have arisen during an 18 months observation period.

Neither intraoperative nor postoperative complications were recorded. One

patient complained of increased compensatory sweating of the trunk.

Thermometrically controlled thoracoscopic sympathectomy is expected to improve

the various forms of treatment available for sympathetic reflex dystrophies in

the future.

 

PMID: 8211930 [PubMed - indexed for MEDLINE]

 

 

 

301: Br J Surg  1993 Jul;80(7):862

 

Electrocautery of the upper thoracic sympathetic chain: a simplified technique.

 

Gothberg G, Claes G, Drott C.

 

Department of Surgery, Boras Hospital, Sweden.

 

PMID: 8369917 [PubMed - indexed for MEDLINE]

 

 

 

302: J Pediatr Surg  1993 Jul;28(7):909-11

 

Long-term results of limited thoracic sympathectomy for palmar hyperhidrosis.

 

Hehir DJ, Brady MP.

 

Department of Surgery, Regional Hospital Cork, Ireland.

 

Eighteen children (15 females, 3 males) aged 7 to 15 years underwent resection

of the thoracic sympathetic chain for severe palmar hyperhidrosis. A localized

section of chain immediately below the first thoracic ganglion and including the

second thoracic sympathetic ganglion was removed. Patients were followed for 24

to 136 months. All patients had immediate and permanent abolition of palmar

hyperhidrosis. There was no mortality, one patient developed intermittent ptosis

and myosis, three patients reported compensatory hyperhidrosis and one girl was

unhappy with the cosmetic results. We conclude that thoracic sympathectomy is a

safe and permanent treatment for severe palmar hyperhidrosis in children. In

addition, limited sympathetic resection is associated with a lower incidence of

compensatory hyperhidrosis than conventional more radical sympathectomy.

 

PMID: 8229566 [PubMed - indexed for MEDLINE]

 

 

 

303: BMJ  1993 Jun 26;306(6894):1752

 

Comment on:

 BMJ. 1993 May 8;306(6887):1221-2.

 

Treating hyperhidrosis. Reserve sympathectomy for palmar hyperhidrosis.

 

Gordon A, Collin J.

 

Publication Types:

Comment

Letter

 

PMID: 8343646 [PubMed - indexed for MEDLINE]

 

 

 

304: BMJ  1993 Jun 26;306(6894):1752

 

Comment in:

 BMJ. 1993 Jul 31;307(6899):326.

 

Comment on:

 BMJ. 1993 Jun 26;306(6894):1752

 

Treating hyperhidrosis. Complications of endoscopic sympathectomy.

 

Quinn AC, Edwards RE, Newman PJ, Fawcett WJ.

 

Publication Types:

Comment

Letter

 

PMID: 8343645 [PubMed - indexed for MEDLINE]

 

 

 

305: Harefuah  1993 Jun 15;124(12):748-50, 796

 

[Thoracoscopic resection of upper dorsal sympathetic chain for palmar

hyperhidrosis]

 

[Article in Hebrew]

 

Kopelman D, Schein M, Hashmonai M.

 

Dept of Surgery B, Rambam Medical Center, Haifa.

 

During the past year we have used the thoracoscopic approach in performing

bilateral upper dorsal sympathectomies for the treatment of palmar

hyperhidrosis. We present our first 16 patients. Histological examination proved

that sympathetic ganglia had been resected in all 32 procedures. Immediately

after operation all hands were completely dry and 31 of them remained so on

follow-up 5 months later (97% success rate). The main operative complications

were bleeding in 3 cases (9.4%; only 1 severe), and chest and back pain for more

than 1 week in 8 (50%). The main late sequela was compensatory hyperhidrosis of

the chest and back in 10 cases (62%).

 

PMID: 8375765 [PubMed - indexed for MEDLINE]

 

 

 

306: Br J Surg  1993 Jun;80(6):687-8

 

Comment in:

 Br J Surg. 1993 Oct;80(10):1351.

 

Endoscopic sympathectomy.

 

Hederman WP.

 

Department of Surgery, Mater Misericordiae Hospital, Dublin, Ireland.

 

PMID: 8305007 [PubMed - indexed for MEDLINE]

 

 

 

307: J Vasc Surg  1993 Jun;17(6):1137-9

 

Comment on:

 J Vasc Surg. 1992 Jul;16(1):121-3.

 

Thoracic dorsal sympathectomy for hyperhidrosis: a new approach.

 

Schein M, Kopelman D, Hashmonai M.

 

Publication Types:

Clinical Trial

Comment

Letter

Randomized Controlled Trial

 

PMID: 8505796 [PubMed - indexed for MEDLINE]

 

 

 

308: Thorac Cardiovasc Surg  1993 Jun;41(3):140-6

 

Prerequisites, indications, and techniques of video-assisted thoracoscopic

surgery.

 

Linder A, Friedel G, Toomes H.

 

Schillerhohe Hospital, Gerlingen, Germany.

 

During the last two years video-assisted operative thoracoscopy has introduced

new impetus into thoracic surgery. Today it is viewed as a sparing and safe

alternative to thoracotomy for a wide spectrum of indications. The

prerequisites, instruments, and operative techniques are discussed. In

oncological thoracic surgery it still remains to be verified whether the

criteria of radicality are fulfilled by this new technique. Using video-assisted

operative thoracoscopy, we have successfully operated on 209 patients with the

following indications: recurrent pneumothorax (n = 94), interstitial lung

disease (n = 25), coin lesion (n = 20), pleural effusion (n = 17), hyperhidrosis

(n = 14), mediastinal tumor or lymphoma (n = 10), thoracic empyema (n = 9),

bullous emphysema (n = 8), pleural tumor (n = 5), hematothorax (n = 3),

malignant pericardial effusion (n = 3), and chylothorax (n = 1). The advantages

of this minimally traumatizing operating technique lie in a better view of the

operative site, the objectively measurable reduction in postoperative

restriction, less pain, earlier postoperative mobilization, and shorter hospital

stay. This operating technique, in addition to being sparing, requires markedly

less time than a thoracotomy. The disadvantages are the two-dimensional monitor

picture and, especially, the loss of palpation.

 

PMID: 8367865 [PubMed - indexed for MEDLINE]

 

 

 

309: BMJ  1993 May 8;306(6887):1221-2

 

Comment in:

 BMJ. 1993 Jun 26;306(6894):1752.

 

Treating hyperhidrosis.

 

Quraishy MS, Giddings AE.

 

Publication Types:

Editorial

 

PMID: 8499848 [PubMed - indexed for MEDLINE]

 

 

 

310: Baillieres Clin Endocrinol Metab  1993 Apr;7(2):465-90

 

Sympathetic nervous system disorders in man.

 

Mathias CJ.

 

Department of Medicine, St Mary's Hospital Medical School, Imperial College of

Science, Technology and Medicine, London, UK.

 

The sympathetic nervous system innervates most organs in the body and controls

their function. A variety of disease processes, surgery or drugs can result in

disordered sympathetic nerve function, which can be either localized or more

generalized. Malfunction can result in either sympathetic underactivity (causing

postural hypotension, impotence or anhidrosis) or overactivity (causing

paroxysmal hypertension or hyperhidrosis). The investigation of sympathetic

disorders depends upon the system and organs involved and should include, where

relevant, investigation of the possible aetiological processes. The clinical

features and management of some of the major disorders affecting the sympathetic

nervous system, including the recently described syndrome of DBH deficiency, are

described.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 8489487 [PubMed - indexed for MEDLINE]

 

 

 

311: Arch Surg  1993 Feb;128(2):237-41

 

Comment in:

 Arch Surg. 1995 Nov;130(11):1243-4.

 

Endoscopic procedures of the upper-thoracic sympathetic chain. A review.

 

Drott C, Gothberg G, Claes G.

 

Department of Surgery, Boras Hospital, Sweden.

 

The upsurge of endoscopic surgical procedures now includes procedures of the

thoracic sympathetic chain. The number of articles on this issue is rapidly

increasing. This article reviews the indications for as well as the technique,

complications, side effects, and results of endoscopic upper-thoracic

sympathetic ablation. Since 1977, nearly 900 cases have been described in the

literature. The main indication is usually hyperhidrosis. The described

techniques vary in detail, but the common denominators are simplicity,

expedience, minimal surgical trauma, few complications, and low cost compared

with standard methods of open surgery. The results are excellent, durable, and

stand well compared with results of previous open techniques. Due to the

overwhelming advantages of endoscopic methods, we can foresee an increasing

adoption of these techniques and a subsequent relegation of the various open

surgical procedures of the upper-thoracic sympathetic chain.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 8431126 [PubMed - indexed for MEDLINE]

 

 

 

312: Neurosurgery  1993 Feb;32(2):327-9

 

Comment in:

 Neurosurgery. 2001 Mar;48(3):702.

 

Comment on:

 Neurosurgery. 1992 Jan;30(1):131-5.

 

Video endoscopic sympathectomy using a fiberoptic CO2 laser to treat palmar

hyperhidrosis.

 

Chung HY, Seo CG, Lee SG.

 

Publication Types:

Comment

Letter

 

PMID: 8437676 [PubMed - indexed for MEDLINE]

 

 

 

313: Surg Gynecol Obstet  1993 Feb;176(2):151-4

 

Limiting the anatomic extent of upper thoracic sympathectomy for primary palmar

hyperhidrosis.

 

O'Riordain DS, Maher M, Waldron DJ, O'Donovan B, Brady MP.

 

University Department of Surgery, University College and Regional Hospital,

Cork, Ireland.

 

Ninety-four consecutive patients undergoing bilateral sympathectomy of the upper

part of the thorax for primary palmar hyperhidrosis were reviewed. The

supraclavicular operative approach was used and a limited sympathectomy was

performed from below T1 to above T3, denervating the palm only. Follow-up

evaluation was complete in 86 patients at a median period of 31 months. All

patients had complete and permanent relief of palmar hyperhidrosis. However, 19

had compensatory hyperhidrosis and this was the common cause of patient

dissatisfaction. Although axillary denervation was not performed, axillary

sweating was a problem postoperatively in only two patients. Significant

morbidity was minimal; the only permanent disability was in one patient with

Horner's syndrome. Upper thoracic sympathectomy is a safe and effective method

of treatment for primary palmar hyperhidrosis. The low incidence of compensatory

sweating may be explained by the limited extent of the sympathectomy. Axillary

sweating is rarely a significant postoperative problem, and extensive

sympathectomy to include axillary denervation is unnecessary and should be

avoided to minimize compensatory hyperhidrosis.

 

PMID: 8421803 [PubMed - indexed for MEDLINE]

 

 

 

314: Ann Chir  1993;47(8):769-72

 

[Chylothorax: a rare complication of transaxillary thoracic sympathectomy]

 

[Article in French]

 

Levy I, Ariche A, Sebbag G, Hoda J.

 

Service de Chirurgie A, Hospitalo-Universitaire Soroka, Universite Ben Gourion

du Neguev, Beer Sheva 84101, Israel.

 

Transaxillary upper thoracic sympathectomy is a safe surgical procedure for the

treatment of palmar hyperhidrosis. Although thoracic complications such as

hemothorax and pneumothorax occasionally occur following this procedure

chylothorax is an extremely rare complication. From 1978 to 1991, 215

consecutive patients underwent upper thoracic sympathectomy for the treatment of

palmar hyperhidrosis in our institution. We report the surgical management of

one patient who developed an intractable chylous fistula which did not respond

to non-surgical treatment. Attempts at non-surgical management of the disease,

with aspiration therapy, tube thoracostomy and the administration of medium

chain triglyceride diet, should be tried first. If, however, this is not

successful within two weeks, one should not wait for further metabolic and

nutritional impairment before instituting surgical treatment. We believe that

proximal thoracic duct ligation is a relatively simple and effective means of

controlling chylothorax.

 

PMID: 8311411 [PubMed - indexed for MEDLINE]

 

 

 

315: Scand J Plast Reconstr Surg Hand Surg  1993;27(1):29-33

 

Endoscopic electrocautery of the thoracic sympathetic chain. A minimally

invasive way to treat palmar hyperhidrosis.

 

Claes G, Drott C, Gothberg G.

 

Department of Surgery, Boras Hospital, Sweden.

 

Four hundred and fifty patients with palmar hyperhidrosis have undergone

endoscopic thoracic sympathetic electrocautery since 1987 in our department. The

procedure requires only minor modifications of standard laparoscopic and

urological equipment. The median operating time for a bilateral procedure was 31

minutes (15-120), hospital stay was 1 day postoperatively (1-8), and patients

returned to work within 4 (1-40) days. Complications in the whole material were

few and mild, pneumothorax (n = 2), haemothorax (n = 1), and Horner's syndrome

(n = 1). Five patients required reoperation (four because of primary failure to

destroy the nerve and one for recurrent symptoms). The first consecutive 130 of

these patients have been followed up by a questionnaire. At follow-up (median

196 days after operation, range 35-1419) all patients but three, who are

awaiting reoperation were satisfied with the result. The discomfort and side

effects of the operation were in most cases mild and short. This technique makes

it possible to widen the indications for operation for people with palmar

hyperhidrosis.

 

PMID: 8493481 [PubMed - indexed for MEDLINE]

 

 

 

316: J Auton Nerv Syst  1992 Dec;41(3):215-9

 

Normal sympathetic nerve activity in a reflex sympathetic dystrophy with marked

skin vasoconstriction.

 

Casale R, Elam M.

 

Service of Clinical Neurophysiology, Foundation Clinica del Lavoro IRCCS-Pavia,

Montescano, Italy.

 

Intraneural recording in skin fascicles of the left ulnar nerve was performed in

a 51 year old patient with reflex sympathetic dystrophy (allodynia, marked

vasoconstriction in the ulnar part of the left hand) following Vth finger

amputation. Skin sympathetic activity showed normal characteristics with a weak

discharge at rest whereas bursts of impulses could be evoked by

sympatho-excitatory stimuli. Sympathetic bursts induced by painful stimuli were

few, also during long-lasting allodynic pain. Sympathetic bursts induced by

inspiratory gasps were not associated with excacerbation of pain. The

discrepancy between the marked skin vasoconstriction and the low resting

sympathetic discharge underlines the fact that sympathetic effector organ

hyperactivity (i.e. vasoconstriction and/or hyperhidrosis) cannot be taken as

evidence for increased sympathetic discharge. In the present case, the

neuropathic pain syndrome cannot be considered as maintained by an increased

sympathetic neural discharge to the symptomatic limb.

 

PMID: 1289385 [PubMed - indexed for MEDLINE]

 

 

 

317: Ma Zui Xue Za Zhi  1992 Dec;30(4):277-82

 

Sudden cardiac arrest during left thoracoscopic T2 sympathectomy.

 

Chow TC, Tan CT, Hwang YS, Ting MC, Chen YP, Lin JC, Lin CC.

 

Department of Anesthesiology, Show Chwan Memorial Hospital, Changhua.

 

PMID: 1344244 [PubMed - indexed for MEDLINE]

 

 

 

318: Semin Neurol  1992 Dec;12(4):394-407

 

Autonomic neurodermatology (Part II): Disorders of sweating and flushing.

 

Freeman R, Waldorf HA, Dover JS.

 

Division of Neurology, New England Deaconess Hospital, Boston, MA 02215.

 

Publication Types:

Review

Review, Academic

 

PMID: 1485049 [PubMed - indexed for MEDLINE]

 

 

 

319: Br J Anaesth  1992 Oct;69(4):349-51

 

Comment in:

 Br J Anaesth. 1993 Apr;70(4):491-2.

 Br J Anaesth. 1993 Apr;70(4):492.

 

Anaesthesia for transthoracic endoscopic sympathectomy in the treatment of upper

limb hyperhidrosis.

 

Jedeikin R, Olsfanger D, Shachor D, Mansoor K.

 

Department of Anaesthesiology and Intensive Care, Sackler School of Medicine,

University of Tel Aviv, Meir Hospital, Kfar Saba, Israel.

 

Renewed interest has been shown in transthoracic endoscopic sympathectomy (TES)

for the treatment of upper limb hyperhidrosis. We review our experience and

discuss the anaesthetic technique and perioperative problems encountered in 58

patients undergoing TES for hyperhidrosis. Patients were monitored for arterial

pressure, heart rate, ECG, pulse oximetry (SpO2), end-tidal carbon dioxide

concentration, peak inspired airway pressure and skin temperature. General

anaesthesia, with a double-lumen endobronchial tube, enabled the lungs to be

collapsed alternately, thereby ensuring easy and clear access to the sympathetic

chain. Controlled ventilation with 100% inspired oxygen was necessary to obviate

hypoxaemia. In two patients, severe hypotension and bradycardia occurred during

insufflation of carbon dioxide into the chest cavity. Four patients required

underwater drainage of the pleural cavity for treatment of pneumothorax or

haemothorax. The success and safety of the procedure depends on a scrupulous

anaesthetic technique.

 

PMID: 1419441 [PubMed - indexed for MEDLINE]

 

 

 

320: Can J Surg  1992 Oct;35(5):509-11

 

Thoracoscopic transthoracic dorsal sympathectomy.

 

Pace RF, Brown PM, Gutelius JR.

 

Department of Surgery, Queen's University, Kingston General Hospital, Ont.

 

The authors report on the three patients who underwent thoracoscopic

transthoracic dorsal sympathectomies by the techniques of minimal-access surgery

learned from laparoscopic cholecystectomy. All three had histologic confirmation

of removal of the sympathetic chain and have had an encouraging early

postoperative result. The authors believe that thoracoscopic transthoracic

dorsal sympathectomy can be accurately and safely performed and will become the

method of choice for dorsal sympathectomy.

 

PMID: 1393866 [PubMed - indexed for MEDLINE]

 

 

 

321: Clin Auton Res  1992 Oct;2(5):349-52

 

Endoscopic transthoracic sympathectomy for idiopathic upper limb hyperhidrosis.

 

Masters A, Rennie JA.

 

Department of Surgery, King's College Hospital, Denmark Hill, London, UK.

 

A 5-year experience of 51 endoscopic transthoracic dorsal sympathectomies for

idiopathic palmar hyperhidrosis in 26 patients is presented. Fifty-two percent

complained of excessive sweating over their hands, 28% of axillary sweating and

20% over both areas, with a mean duration of 10 years. The second, third and

fourth thoracic ganglia and their interconnecting fibres on the affected side

were ablated using diathermy cautery. Over a mean follow up time of 26 months,

this procedure was successful in curing or improving intractable sweating in

92%. However, axillary sweating was less well controlled than in the palms with

20% of patients describing residual wetness in the axilla. Compensatory sweating

(75%) and gustatory sweating (48%) were the commonest side effects; despite

this, most patients were satisfied with the functional and cosmetic outcome.

Other complications included a temporary Horner's syndrome in one patient, a

pneumothorax in the immediate post-operative period in another and a unilateral

non-infective reactionary pleural effusion in a third. Two patients developed

recurrence of palmar hyperhidrosis within 6 months of surgery. One has been

successfully treated by re-operation on the affected side. All patients

complained of mild to moderate interscapular chest pain which was easily

controlled by non-steroidal anti-inflammatory agents, and resolved within 7-10

days post-operatively. The technique of endoscope transthoracic sympathectomy is

effective, relatively simple to perform and usually requires only an overnight

stay. It is recommended as the surgical treatment of choice for upper limb

hyperhidrosis unresponsive to conservative measures.

 

PMID: 1422103 [PubMed - indexed for MEDLINE]

 

 

 

322: Br J Surg  1992 Sep;79(9):975-6

 

Comment on:

 Br J Surg. 1992 Mar;79(3):268-71.

 

Upper thoracic sympathectomy for primary palmar and axillary hyperhidrosis:

long-term follow up.

 

Byrne J, Walsh TN, Hederman WP.

 

Publication Types:

Comment

Letter

 

PMID: 1422775 [PubMed - indexed for MEDLINE]

 

 

 

323: Eur J Vasc Surg  1992 Sep;6(5):558-62

 

Endoscopic transthoracic sympathectomy: experience in the south west of England.

 

Adams DC, Wood SJ, Tulloh BR, Baird RN, Poskitt KR.

 

Department of Vascular Surgery, Cheltenham General Hospital, U.K.

 

Thoracic sympathectomy has an established role in the management of primary

palmar and axillary hyperhidrosis, Raynaud's phenomenon and occlusive vascular

disease. Potential problems with traditional surgical approaches to the

sympathetic chain include poor exposure, risk of damage to adjacent structures

and postoperative pain. A minimally invasive endoscopic approach helps to

overcome these problems. Using this technique, 45 procedures have been performed

on 26 patients in two districts in the South West of England over the past five

years. Follow-up information was available for 39 procedures. All 27 procedures

for hyperhidrosis and both for occlusive vascular disease have produced a

long-term improvement. Nine of the 10 procedures for Raynaud's phenomenon have

also produced some degree of long-term improvement. Complications included four

asymptomatic pneumothoraces, two patients with temporary unilateral Horner's

syndrome and two instances of intercosto-brachial numbness. On the positive

side, patients expressed satisfaction with the efficacy, rapid recovery and

small unobtrusive scars produced by the procedure. Endoscopic transthoracic

sympathectomy is effective, safe and well accepted by patients and we believe is

now the method of choice for this procedure.

 

PMID: 1397353 [PubMed - indexed for MEDLINE]

 

 

 

324: Br J Surg  1992 Aug;79(8):752

 

Efficacy of endoscopic transthoracic sympathectomy assessed by peroperative

palmar temperature measurement.

 

Chester JF, Jeddy TA, Taylor RS, Dormandy JA, Allt-Graham J.

 

Department of Surgery, Taunton and Somerset Hospital, Taunton, UK.

 

PMID: 1393460 [PubMed - indexed for MEDLINE]

 

 

 

325: Can J Surg  1992 Aug;35(4):414-6

 

Transaxillary endoscopic laser sympathectomy.

 

Austin JJ, Doobay B, Schatz SW.

 

McMaster University Clinic, Hamilton General Hospital, Ont.

 

The authors describe a technique of achieving sympathetic denervation of the

upper limbs in a 20-year-old woman with hyperhidrosis. A thoracoscope was

inserted through a short incision in the axilla. A fibreoptic wave guide was

passed through the thoracoscope to allow photocoagulation of the second thoracic

sympathetic ganglion by Nd:YAG laser irradiation. The procedure was well

tolerated and subsequent scar formation was unobtrusive.

 

PMID: 1498742 [PubMed - indexed for MEDLINE]

 

 

 

326: Ann Vasc Surg  1992 Jul;6(4):390-2

 

Transthoracic endoscopy for upper thoracic chemical sympathectomy.

 

Bardaxoglou E, Reigner B, Enon B, Tolstuchow N, Lescalie F, Peret M, Chevalier

JM.

 

Service de Chirurgie Vasculaire et Thoracique, Centre Hospitalier et

Universitaire, Angers, France.

 

Beginning in April 1989, we have performed eight upper thoracic chemical

sympathectomies by transthoracic endoscopy. The indications were occlusive

arterial disease in four patients and Raynaud's syndrome and palmar

hyperhidrosis in two patients each. Transthoracic endoscopy was performed under

general anesthesia, through the third costal interspace on the anterior

mid-clavicular line. Five ml of phenol were injected into the parietal pleura

covering the three proximal thoracic ganglia. The duration of thoracic drainage

was 24 hours. The postoperative course was uneventful except for one case of

subcutaneous emphysema and transient Horner's syndrome in three instances. There

were no initial failures. Because of its simplicity and the short

hospitalization period, chemical sympathectomy by transthoracic endoscopy

constitutes a valuable alternative to conventional surgery. This technique is,

however, limited in the case of antecedent pleuropulmonary disorders.

 

PMID: 1390030 [PubMed - indexed for MEDLINE]

 

 

 

327: J Vasc Surg  1992 Jul;16(1):121-3

 

Comment in:

 J Vasc Surg. 1993 Jun;17(6):1136.

 J Vasc Surg. 1993 Jun;17(6):1137-9.

 

Thorascopic dorsal sympathectomy for hyperhidrosis: a new approach.

 

Appleby TC, Edwards WH Jr.

 

Department of Surgery, St. Thomas Hospital, Nashville, TN.

 

PMID: 1619713 [PubMed - indexed for MEDLINE]

 

 

 

328: Lakartidningen  1992 Apr 22;89(17):1477-8

 

[Good results and low number of complications with minimal invasive endoscopic

surgery of palmar sweating]

 

[Article in Swedish]

 

Claes G, Drott C, Gothberg G.

 

Kirurgiska kliniken, bada vid Boras lasarett, Boras.

 

PMID: 1573936 [PubMed - indexed for MEDLINE]

 

 

 

329: Lakartidningen  1992 Apr 22;89(17):1478

 

[Endoscopic thoracic sympathectomy is a simple and effective method against

palmar sweating]

 

[Article in Swedish]

 

Norback B, Svartholm E.

 

Bada vid kirurgiska kliniken, Lanssjukhuset, Jonkoping.

 

PMID: 1573937 [PubMed - indexed for MEDLINE]

 

 

 

330: Angiology  1992 Apr;43(4):336-41

 

Telford's operation for primary palmar hyperhidrosis.

 

Gyftokostas D, Koutsoumbelis C, Daskalakis E, Bouhoutsos J.

 

Unit of Peripheral Vascular Surgery, 401 Army Hospital, Athens, Greece.

 

Bilateral upper dorsal sympathectomy via the supraclavicular approach was

performed in 42 patients for palmar hyperhidrosis. In 16 patients (32

extremities) the effect of sympathectomy on digital circulation was evaluated

objectively, in comparison with that of 15 control subjects. Mean values of

finger temperature and of digital systolic pressure increased by 6.9 degrees C

and 36 mmHg respectively after operation, whereas an increase of digital blood

flow and a decrease of the time of the clearance of 99mTc by approximately 60%

were recorded. Differences between preoperative and postoperative values and

those of controls were statistically significant. Clinical results of treatment

remain satisfactory after a mean follow-up period of thirty-two months with no

case of recurrence. Permanent decrease of plantar hyperhidrosis was recorded by

14 patients. The advantages of Telford's operation over other methods of upper

extremity sympathetic denervation are discussed.

 

PMID: 1558319 [PubMed - indexed for MEDLINE]

 

 

 

331: Ann Surg  1992 Mar;215(3):289-93

 

Endoscopic transthoracic sympathectomy in the treatment of hyperhidrosis.

 

Edmondson RA, Banerjee AK, Rennie JA.

 

Department of Surgery, King's College Hospital, Denmark Hill, London, England.

 

A 5-year experience of 50 endoscopic transaxillary dorsal sympathectomies is

presented. The procedure was successful in either curing or improving the

symptoms of hyperhidrosis in the great majority of patients. The commonest side

effects were compensatory sweating (75%) and gustatory sweating (48%); despite

this, there was an extremely high level of patient satisfaction. Permanent

Horner's syndrome did not occur. The procedure is effective, simple, cheap, and

requires only an overnight stay; and is recommended as the method of choice for

the surgical treatment of upper limb hyperhidrosis.

 

PMID: 1543403 [PubMed - indexed for MEDLINE]

 

 

 

332: Br J Surg  1992 Mar;79(3):268-71

 

Comment in:

 Br J Surg. 1992 Sep;79(9):975-6.

 

Upper thoracic sympathectomy for primary palmar hyperhidrosis: long-term

follow-up.

 

Hashmonai M, Kopelman D, Kein O, Schein M.

 

Department of Surgery B, Rambam Medical Centre, Haifa, Israel.

 

Primary palmar hyperhidrosis is a functionally and socially disabling condition.

Upper thoracic sympathectomy is the best curative treatment. Several surgical

approaches have been suggested and, recently, less invasive techniques have been

communicated. To evaluate which method is the best, the short- and particularly

the long-term results must be compared. A series is presented of 170 upper

thoracic sympathectomies by the supraclavicular approach performed on 85

patients with palmar hyperhidrosis. Follow-up for a mean of 8.3 years was

obtained on 124 operated limbs. The immediate failure rate for relief from

hyperhidrosis was 2.4 per cent and hyperhidrosis recurred in another 4.1 per

cent of limbs after a period of between 2 and 18 months. Thirteen per cent of

patients were dissatisfied with the results of operation, one because of

persisting vasomotor rhinitis, two because of Horner's syndrome and five because

of persisting or recurrent hyperhidrosis. Satisfactory results in approximately

87 per cent of cases make the operation rewarding. This outcome should be

compared with the long-term results of other methods, such as percutaneous

phenol injection and the transthoracoscopic approach, when such data are

compiled and published.

 

PMID: 1555100 [PubMed - indexed for MEDLINE]

 

 

 

333: J Laparoendosc Surg  1992 Feb;2(1):1-6

 

Extended thoracoscopic T2-sympathectomy in treatment of hyperhidrosis:

experience with 130 consecutive cases.

 

Lin CC.

 

Surgical Department, Tainan Municipal Hospital, Taiwan, Republic of China.

 

A new method of thoracoscopic T2-sympathectomy mentioned in a previous report

was used on 36 cases of hyperhidrosis at Tainan Municipal Hospital in Taiwan

between October 1, 1989 and July 31, 1990. To reduce the possibility of

incomplete resection of sympathetic nerve tracts, including ganglions and their

regeneration, the method was modified on August 1, 1990. Thereafter, routine

total removal of T2 and T3 sympathetic ganglions, as well as wide lateral

incisions of the pleura on the second, third, and fourth rib beds were performed

for treatment of hyperhidrosis. This newly modified method, "extended

thoracoscopic T2-sympathectomy," can be performed easily by thoracoscopic

approach in the treatment of hyperhidrosis palmaris. From August 1, 1990 to May

31, 1991, 130 consecutive cases of hyperhidrosis (56 males and 74 females)

ranging in age from 8 to 51 years underwent extended thoracoscopic

T2-sympathectomy. In addition to a nearly 100% cure rate of hyperhidrosis

palmaris, significant saving in operative time and hospital stay were achieved.

High simultaneous cure rate (70.6%) and subjective improvement (17.4%) of

excessive sweating of feet (hyperhidrosis plantaris) were also noted in the 109

cases followed up, and complications were minor. Extended thoracoscopic

T2-sympathectomy is not only a time-saving method but also a very simple and

effective method in the treatment of hyperhidrosis. It is worthy of being

propagated worldwide.

 

PMID: 1576368 [PubMed - indexed for MEDLINE]

 

 

 

334: Lasers Surg Med  1992;12(3):308-12

 

Laser endoscopic sympathectomy for palmar hyperhidrosis.

 

Kao MC.

 

Department of Surgery, College of Medicine, National Taiwan University, Taipei,

Republic of China.

 

Hyperhidrosis palmaris is a common disorder among the Orientals. Despite

numerous therapeutic modalities in practice, none has proved entirely

satisfactory. With the introduction of video-endoscopic surgery, we combined

this system with a fiber optic Nd-YAG laser unit, electrocautery, and a laser

Doppler flowmeter to design a new and promising therapeutic technique for palmar

hyperhidrosis. General anesthesia with alternating one-lung ventilation is

essential for a safe and smooth endoscopic sympathectomy. An operating endoscope

was introduced into thoracic cavity via the second intercostal space and then

attached to a CCD camera video system, which provided clear visibility of the

sympathetic trunk in most cases. The proper level of the sympathetic trunk was

further confirmed with the aid of vasomotor response of the palmar skin

resulting from electric stimulation on the related sympathetic trunk. Finally,

the confirmed target was precisely vaporized with a low power Nd-YAG laser

through an endoscope. Twenty patients underwent bilateral sympathectomy, mostly

on T2 and its adjacent trunk. This technique did not cause any injury to the

lung or bleeding. No Horner's syndrome was produced. It provided a precise

ganglionectomy on a confirmed target under clear magnified vision. Consequently,

a definite and long-lasting therapeutic effect seemed warranted. It was

considered to be a relative minor and safe procedure causing minimal discomfort

and an almost invisible scar without producing serious complications. It also

shortened the operation time and hospital stay remarkably in comparison with

other open sympathectomy procedures.

 

PMID: 1508026 [PubMed - indexed for MEDLINE]

 

 

 

335: Neurosurgery  1992 Jan;30(1):131-5

 

Comment in:

 Neurosurgery. 1993 Feb;32(2):327-9.

 Neurosurgery. 2001 Mar;48(3):702.

 

Video endoscopic sympathectomy using a fiberoptic CO2 laser to treat palmar

hyperhidrosis.

 

Kao MC.

 

Department of Surgery, Laser Medicine Research Center, College of Medicine,

National Taiwan University, Taipei, Republic of China.

 

Palmar hyperhidrosis is a common disorder among orientals. A new therapeutic

technique for this disorder has been designed by combining a computer compact

disc video endoscopic system with a fiberoptic CO2 surgical laser unit. The

operation is performed under general anesthesia with alternating one-lung

ventilation. There are three important aids in localizing the correct

sympathetic segment: 1) direct visualization of its magnified image on the

television monitor; 2) identification with an electrode probe palpation at its

presumed location; and 3) monitoring the microvasomotor changes on the skin of

the finger resulting from electrical stimulation of the sympathetic trunk.

Subsequently, the confirmed sympathetic target is vaporized using a low power

CO2 laser under direct vision on the television monitor. The laser is delivered

to the target by a small optical fiber passing through a throacoscope, which is

introduced into the thoracic cavity via the intercostal space between the second

and third ribs at the midclavicular line. Fourteen palmar hyperhidrosis patients

were successfully treated by this method. No complications, such as Horner's

syndrome, bleeding, or intercostal neuralgia, were encountered. Although the

number of cases treated was small, and the follow-up period was short, the

evidence indicates that a definite sympathectomy on a confirmed segment under

magnified vision is possible with this procedure, and could warrant a definite

and long-lasting therapeutic effect. Based on our experience, the method is

considered a relatively minor and safe procedure, causing minimal discomfort and

almost invisible scars. The operation time and hospital stay were remarkably

shortened in comparison with other conventional sympathectomy procedures.

 

PMID: 1738444 [PubMed - indexed for MEDLINE]

 

 

 

336: Br J Surg  1991 Nov;78(11):1401

 

Comment on:

 Br J Surg. 1991 Mar;78(3):279-83.

 

Surgical management of primary hyperhidrosis.

 

Pillay PK.

 

Publication Types:

Comment

Letter

 

PMID: 1760714 [PubMed - indexed for MEDLINE]

 

 

 

337: Br J Surg  1991 Aug;78(8):1019-20

 

Comment on:

 Br J Surg. 1991 Mar;78(3):279-83.

 

Surgical management of primary hyperhidrosis.

 

Adams DC, Poskitt KR.

 

Publication Types:

Comment

Letter

 

PMID: 1913099 [PubMed - indexed for MEDLINE]

 

 

 

338: Br J Surg  1991 Jun;78(6):760

 

Comment on:

 Br J Surg. 1990 Sep;77(9):1046-9.

 

Endoscopic transthoracic electrocautery of the sympathetic chain for palmar and

axillary hyperhidrosis.

 

Claes G, Gothberg G.

 

Publication Types:

Comment

Letter

 

PMID: 2070248 [PubMed - indexed for MEDLINE]

 

 

 

339: Br J Surg  1991 Jun;78(6):761

 

Comment on:

 Br J Surg. 1991 Mar;78(3):279-83.

 

Surgical management of primary hyperhidrosis.

 

Birnstingl M.

 

Publication Types:

Comment

Letter

 

PMID: 2070250 [PubMed - indexed for MEDLINE]

 

 

 

340: Br J Surg  1991 May;78(5):635

 

Comment on:

 Br J Surg. 1990 Sep;77(9):1046-9.

 

Endoscopic transthoracic electrocautery of the sympathetic chain for palmar and

axillary hyperhidrosis.

 

Weale F.

 

Publication Types:

Comment

Letter

 

PMID: 2059831 [PubMed - indexed for MEDLINE]

 

 

 

341: Singapore Med J  1991 Apr;32(2):119-20

 

Sympathectomy for wet, dripping palms.

 

Tan KK.

 

Department of Neurosurgery, Tan Tock Seng Hospital, Singapore.

 

An analysis of upper thoracic sympathectomy for palmar hyperhydrosis performed

in a Neurological Department for the past ten years via several surgical

approaches suggests that the posterior median approach is preferable.

Histological confirmation of ganglion cells at time of surgery is recommended.

 

PMID: 2042071 [PubMed - indexed for MEDLINE]

 

 

 

342: Br J Surg  1991 Mar;78(3):279-83

 

Comment in:

 Br J Surg. 1991 Aug;78(8):1019-20.

 Br J Surg. 1991 Jun;78(6):761.

 Br J Surg. 1991 Nov;78(11):1401.

 

Surgical management of primary hyperhidrosis.

 

Moran KT, Brady MP.

 

University Department of Surgery, Regional Hospital, Cork, Ireland.

 

Primary hyperhidrosis, although lacking a precise definition and of unknown

aetiology, disrupts professional and social life and may lead to emotional

problems. A variety of treatment methods are used to control or reduce the

profuse sweating which involves mainly the palms, soles and axillae. The

simplest method, the application of topical agents, is usually attempted first

for axillary and plantar sweating. Iontophoresis may provide relief especially

in patients with plantar or palmar involvement. In severe cases operative

intervention is necessary. Excision of sweat glands is successful in patients

with axillary hyperhidrosis but the role of suction-assisted removal of axillary

sweat glands remains to be determined. Sympathectomy remains the standard by

which other treatments must be judged. For upper thoracic sympathectomy a

variety of surgical approaches are used with satisfactory relief of

hyperhidrosis. Complications related to the surgical approach, such as Horner's

syndrome, brachial plexus injuries, pneumothorax and painful scars may occur,

while following sympathectomy compensatory hyperhidrosis is usual and

hyperhidrosis may recur. Plantar hyperhidrosis which may be exacerbated or

ameliorated by upper thoracic sympathectomy and which fails to respond to

non-operative intervention is relieved by lumbar sympathectomy.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 2021839 [PubMed - indexed for MEDLINE]

 

 

 

343: JAMA  1991 Feb 6;265(5):651

 

Hyperhidrosis.

 

Sato K.

 

University of Iowa Medical School, Iowa City.

 

PMID: 1987421 [PubMed - indexed for MEDLINE]

 

 

 

344: Br J Surg  1991 Feb;78(2):252

 

Comment on:

 Br J Surg. 1990 Sep;77(9):1046-9.

 

Endoscopic transthoracic electrocautery of the sympathetic chain for palmar and

axillary hyperhidrosis.

 

Cameron A.

 

Publication Types:

Comment

Letter

 

PMID: 2015492 [PubMed - indexed for MEDLINE]

 

 

 

345: J R Soc Med  1991 Feb;84(2):114-5

 

Thoracic endoscopic sympathectomy for palmar hyperhidrosis in an adolescent

female.

 

Salob SP, Atherton DJ, Kiely EM.

 

Department of Dermatology, Hospital for Sick Children, London.

 

PMID: 1999811 [PubMed - indexed for MEDLINE]

 

 

 

346: Br J Surg  1990 Dec;77(12):1435

 

Comment on:

 Br J Surg. 1990 Sep;77(9):1046-9.

 

Endoscopic transthoracic electrocautery of the sympathetic chain for palmar and

axillary hyperhidrosis .

 

Banerjee AK, Edmonson R, Rennie JA.

 

Publication Types:

Comment

Letter

 

PMID: 2276033 [PubMed - indexed for MEDLINE]

 

 

 

347: Lakartidningen  1990 Oct 10;87(41):3318-9

 

[Endoscopic thoracic sympathectomy. A surgical method employed in severe hand

sweating]

 

[Article in Swedish]

 

Gothberg G, Hyltander A, Claes G.

 

Sahlgrenska sjukhuset, Goteborg.

 

PMID: 2233003 [PubMed - indexed for MEDLINE]

 

 

 

348: J Invest Dermatol  1990 Oct;95(4):393-6

 

The innermost cell layer of the outer root sheath is positive with Ki-67.

 

Miyauchi S, Hashimoto K, Miki Y.

 

Department of Dermatology, University of Ehime, School of Medicine, Japan.

 

The expression of a cell proliferation-associated human nuclear antigen was

immunohistochemically studied in human anagen hair and hair follicles using the

monoclonal antibody Ki-67. The reaction of Ki-67 in mature anagen hair follicles

was observed in the hair matrix cells and outer root sheath (ORS) cells. Nuclear

 

staining was seen in a small number of matrix cells and in some ORS cells; this

finding corresponded to the thymidine or bromodeoxyuridine labeling studies

previously reported. In addition, there were two different patterns of

cytoplasmic staining in the ORS: strong staining of the innermost cells (IMC)

and weaker staining of the other ORS cells in the isthmus. Ki-67 reactivity of

the IMC layer was observed at each stage of anagen and was regularly seen from

the upper bulb to the isthmus. Ki-67 is a commercially available antibody that

detects cycling cells. However, the IMCs in anagen hair follicles showed

cytoplasmic labeling by Ki-67 from the matrix cells in the upper bulb to the

distal portion of the isthmus.

 

PMID: 2212724 [PubMed - indexed for MEDLINE]

 

 

 

349: Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr  1990 Oct;153(4):400-3

 

Palmar hyperhidrosis CT guided chemical percutaneous thoracic sympathectomy.

 

Adler OB, Engel A, Rosenberger A, Dondelinger R.

 

Department of Diagnostic Radiology, Rambam Medical Center, Faculty of Medicine,

Technion-Israel Institute of Technology, Haifa.

 

Palmar hyperhidrosis or excessive sweating of the hands causes, to those

affected, emotional and physical disturbance and impediment in professional and

social life. The cause is unknown. Sweat glands are innervated by the

sympathetic chain of the autonomous nervous system. The center of sympathetic

regulation of the upper extremities is located between the segments of D.2-D.9

of the spinal cord. Accepted treatment consists of surgery aimed to excise the

third thoracic sympathetic ganglion. Besides the surgical procedure as such, and

its complications, there are complications inherent to the excision of the

ganglion. These are Horner's syndrome, compensatory sweating in other parts of

the body, and recurrence of sweating. CT guided chemical percutaneous thoracic

sympathectomy presents an alternative, which in the event of failure does not

prevent ensuing surgery. The preliminary experience with this procedure in 50

patients is presented and discussed.

 

PMID: 2171085 [PubMed - indexed for MEDLINE]

 

 

 

350: Ugeskr Laeger  1990 Sep 24;152(39):2863-4

 

[Hyperhidrosis. Hypnotherapy of 2 patients with hyperhidrosis]

 

[Article in Danish]

 

Zachariae B, Bjerring P.

 

Psykologisk Institut, Aarhus Universitet.

 

Two cases of hypnotherapeutic treatment of psychogenic hyperhidrosis are

presented. In both cases, organic aetiology could be excluded and conventional

medical treatment modalities had no effect. In both cases, it was possible to

modulate sweating in the trance state within less than a minute, thus supporting

other reported cases of the effect of hypnotically induced modulation of

autonomic responses. In the first case the psychological dynamics behind the

physiological symptoms seemed unrelated to fundamental emotional and personal

problems and relaxation and conditioning techniques in hypnosis had a positive

effect in reducing the sweating to both objectively and subjectively socially

acceptable standards. In the second case the hyperhidrosis was related to more

fundamental personality problems and short term hypnotherapy proved ineffective

in treating the condition.

 

PMID: 2219522 [PubMed - indexed for MEDLINE]

 

 

 

351: Br J Surg  1990 Sep;77(9):1046-9

 

Comment in:

 Br J Surg. 1990 Dec;77(12):1435.

 Br J Surg. 1991 Feb;78(2):252.

 Br J Surg. 1991 Jun;78(6):760.

 Br J Surg. 1991 May;78(5):635.

 

Endoscopic transthoracic electrocautery of the sympathetic chain for palmar and

axillary hyperhidrosis.

 

Byrne J, Walsh TN, Hederman WP.

 

Department of Surgery, Mater Misericordiae Hospital, Dublin, Ireland.

 

Endoscopic transthoracic electrocautery of the sympathetic chain has been the

preferred treatment for palmar or axillary hyperhidrosis in this unit since

1980. A retrospective study was carried out of the first 112 patients with case

material derived from a postal questionnaire, chart review and outpatient

assessment. Eighty-five patients undergoing bilateral transthoracic

electrocautery who replied to the questionnaire (76 per cent response rate) form

the basis of this study. There were 65 females and 20 males with a mean age of

24.3 years (range 15-40 years). The hands alone were affected in 20 patients (24

per cent), the axillae alone in 17 (20 per cent) and both areas in 48 (56 per

cent). Mean hospital stay was 3.1 days (range 1-7 days). Outcome was assessed by

92 per cent of patients immediately after operation as 'very much improved' or

'moderately improved', and this assessment persisted in 85 per cent after a mean

follow-up of 43 months (range 3-95 months). Cosmetic results were rated as

satisfactory by 95 per cent. Apart from pain after operation, morbidity was

limited to transient Horner's syndrome in three patients, surgical emphysema in

three, and pneumothorax requiring a chest drain in one. A repeat procedure was

needed in one patient because of an inadequate first operation. Some

compensatory hyperhidrosis occurred in 54 (64 per cent) patients. As a minimally

invasive procedure, endoscopic transthoracic electrocautery should be considered

the treatment of choice for palmar and axillary hyperhidrosis.

 

PMID: 2131796 [PubMed - indexed for MEDLINE]

 

 

 

352: J Formos Med Assoc  1990 May;89(5):403-5

 

Bilateral simultaneous transaxillary sympathectomy in treatment of palmar

hyperhidrosis: report of 60 cases.

 

Chao C, Lin HE, Lo WT, Hung SY.

 

Department of Surgery, Naval General Hospital, Tsoying, Kaohsiung.

 

Bilateral simultaneous transaxillary sympathectomies (BSTS) were established in

order to achieve a one-stage transaxillary sympathectomy in the treatment of

palmar hyperhidrosis. The features of the BSTS were the patient's supine

operative position, parapectoral incision, and bilateral simultaneous

procedures. BSTS were safely performed on 60 patients during a 5-year period. No

serious complications or recurrences were encountered. The clinical results

suggest that BSTS is the technique of choice for one-stage transaxillary

sympathectomy in the treatment of palmar hyperhidrosis.

 

PMID: 1977853 [PubMed - indexed for MEDLINE]

 

 

 

353: J Am Acad Dermatol  1990 Apr;22(4):699-700

 

Comment on:

 J Am Acad Dermatol. 1989 May;20(5 Pt 1):713-26.

 

Biology of the sweat glands.

 

Tapper R.

 

Publication Types:

Comment

Letter

 

PMID: 2319034 [PubMed - indexed for MEDLINE]

 

 

 

354: Neurology  1990 Mar;40(3 Pt 1):556-7

 

A syndrome of hyperhidrosis, hypothermia, and bradycardia possibly due to

central monoaminergic dysfunction.

 

Arroyo HA, Di Blasi AM, Grinszpan GJ.

 

Hospital Nacional de Pediatrics Prof. Dr. Juan P. Garrahan, Buenos Aires,

Argentina.

 

PMID: 2314606 [PubMed - indexed for MEDLINE]

 

 

 

355: Neth J Med  1990 Feb;36(1-2):53-7

 

Orthostatic hypotension caused by sympathectomies performed for hyperhidrosis.

 

van Lieshout JJ, Wieling W, Wesseling KH, Endert E, Karemaker JM.

 

Department of Medicine, Academic Medical Centre, University of Amsterdam.

 

We studied sympathetic cardiovascular control in a patient after sympathectomies

and found severe hypoadrenergic orthostatic hypotension before and after, but

not during upright exercise. This report is the first to correlate in man

anatomical sympathetic lesions with autonomic function test results and to

document that in a sequence of sympathectomies orthostatic hypotension does not

develop until the major part of splanchnic sympathetic outflow is destroyed.

 

PMID: 2314521 [PubMed - indexed for MEDLINE]

 

 

 

356: Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir  1990;:1325-31

 

[Surgical thoracoscopy]

 

[Article in German]

 

Wittmoser R.

 

Institut fur Neurovegetative Chirurgie und Endoskopie, Dusseldorf.

 

Thoracoscopic adhesiolysis since 1913 (Jacobaeus). Thoracoscopic targets:

Sympathetic system, vagus system, lymphatic system, lung. Indications: Arterial

circulation disturbances, posttraumatic reflexdystrophy ("Sudeck"),

Hyperhidrosis syndromes, erythrodermy syndromes; pain syndromes: causalgiform,

splanchnicotomy for chronic pancreatitis. For peptic jejunal ulcer thoracoscopic

splanchnico-vagotomy. For bronchial asthma selective vagotomy of bronchial rami.

Operative techniques. Hemostasis: low-frequency thermocoagulation, unipolar and

bipolar high-frequency coagulation, with thermostabilisation. Videoendoscopy

with minicameras. Electronic frame freezing for colour slides.

 

PMID: 1983538 [PubMed - indexed for MEDLINE]

 

 

 

357: Surg Endosc  1990;4(4):224-6

 

A new method of thoracoscopic sympathectomy in hyperhidrosis palmaris.

 

Lin CC.

 

Department of Surgery, Tainan Municipal Hospital, Taiwan, Republic of China.

 

Although hyperhidrosis palmaris is a benign condition, it may cause considerable

psychological, social, and occupational disturbances. There are many

conservative measures used to treat hyperhidrosis, but surgical sympathectomy is

the only permanent cure. Of the various surgical approaches to the upper

thoracic sympathetic ganglia, one must select the approach that combines good

functional results and a satisfactory cosmetic outcome with only minor

complications. Twenty-one patients (10 men and 11 women) with hyperhidrosis

palmaris underwent synchronous bilateral T2 sympathectomy between 1 October 1989

and 30 April 1990. These patients underwent a new method of thoracoscopic

sympathectomy without preoperative pneumothorax. All were relieved of excessive

sweating in their upper extremities immediately after the operation. In

addition, the technique led to significant savings in operation and

hospitalization time. We recommend thoracoscopic sympathectomy as the best

approach for sympathectomy in cases of hyperhidrosis palmaris.

 

PMID: 2291165 [PubMed - indexed for MEDLINE]

 

 

 

358: Arch Phys Med Rehabil  1989 Jul;70(7):544-6

 

Management of reflex sweating in spinal cord injured patients.

 

Staas WE Jr, Nemunaitis G.

 

Department of Rehabilitation Medicine, Thomas Jefferson University,

Philadelphia, PA.

 

Reflex sweating can be a problem for cervical spinal cord injured patients.

Patient comfort and skin breakdown have been the major concerns. Five patients

were studied prospectively, using a patch containing 1.5mg of scopolamine.

Patches were changed every third day. Each patient was carefully monitored

before and after application of the patch for signs and symptoms of

anticholinergic side effects such as dizziness, blurred vision and dry mouth.

Patients were also monitored for changes in patch signs before and after use,

including residual urine volumes, blood pressure, heart rate, and mental status.

Our study indicates that topical scopolamine successfully controlled reflex

sweating in 5 patients without anticholinergic side effects.

 

PMID: 2742472 [PubMed - indexed for MEDLINE]

 

 

 

359: J Am Acad Dermatol  1989 May;20(5 Pt 1):713-26

 

Comment in:

 J Am Acad Dermatol. 1990 Apr;22(4):699-700.

 

Biology of sweat glands and their disorders. II. Disorders of sweat gland

function.

 

Sato K, Kang WH, Saga K, Sato KT.

 

Marshall Dermatology Research Laboratories, University of Iowa College of

Medicine, Iowa City 52242.

 

Part I of this article (J Am Acad Dermatol 1989; 20:537-63) focused on normal

sweat gland function. Part II provides a discussion of hyperhidrosis and

hypohidrosis. Hyperhidrotic disorders affect the palms and soles and the axillae

and are associated with previous spinal cord injuries, peripheral neuropathies,

brain lesions, intrathoracic neoplasms, systemic illness, and gustatory

sweating. Hypohidrotic disorders include anhidrotic ectodermal dysplasia,

hereditary sensory neuropathy, Holmes-Adie syndrome, and generalized anhidrosis.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 2654213 [PubMed - indexed for MEDLINE]

 

 

 

360: J Am Acad Dermatol  1989 Apr;20(4):537-63

 

Biology of sweat glands and their disorders. I. Normal sweat gland function.

 

Sato K, Kang WH, Saga K, Sato KT.

 

Marshall Dermatology Research Laboratories, University of Iowa College of

Medicine, Iowa City 52242.

 

The basic mechanisms of sweat gland function and an updated review of some

relatively common disorders of sweat secretion, are presented. Although sweat

secretion and ductal absorption are basically biophysical and biologic cellular

processes, a detailed description of the basic biophysical principles of

membrane transport has been avoided to make the discussion more readable. The

cited references will, however, help those readers primarily interested in the

basic details of sweat gland function. Part I of this article includes a

discussion of morphologic characteristics, central and peripheral nervous

control of sweat secretion, neurotransmitters, intracellular mediators and

stimulus secretion coupling, Na-K-Cl cotransport model for the ionic mechanism

of sweat secretion, ingredients of sweat, ductal function, the pathogenesis of

abnormal sweat gland function in cystic fibrosis, and the discovery of the

apoeccrine sweat gland. Part II, to be published in the May issue of the

Journal, reviews reports of all those major disorders of hyperhidrosis and

hypohidrosis that have appeared in the literature during the past 10 years. It

is hoped that this review will serve as a resource for clinicians who encounter

puzzling disorders of sweating in their patients, as well as for investigators

who wish to obtain a quick update on sweat gland function.

 

Publication Types:

Review

Review, Academic

 

PMID: 2654204 [PubMed - indexed for MEDLINE]

 

 

 

361: J Fam Pract  1989 Apr;28(4):412-5

 

Hyperhidrosis: a management dilemma.

 

Manusov EG, Nadeau MT.

 

475th Medical Group, Yokota Air Base, Japan.

 

Hyperhidrosis is excessive sweating in response to psychological stress and

emotional stimuli. The sweat is usually limited to the palms, soles, and

axillae, and is greatly accentuated by mental stimuli rather than temperature

and exercise. The severity is such that for many, sweating has become socially

and emotionally devastating and may predispose to other cutaneous diseases. More

than 60 research papers on eccrine glands and sweating have been published since

1978. Little progress, however, has been made on the control of hyperhidrosis,

and the process remains a treatment dilemma among both family physicians and

dermatologists. The many treatment modalities documented in the literature have

been for the most part unsuccessful or unacceptable. This report describes the

use of phenoxybenzamine, an alpha-adrenergic antagonist, for control of

excessive sweating in two patients. After a trial of topical medication,

phenoxybenzamine is useful for the reduction of sweating to an acceptable level.

 

PMID: 2703812 [PubMed - indexed for MEDLINE]

 

 

 

362: Neurosurgery  1989 Mar;24(3):449-52

 

Electrophysiological aid in high thoracic sympathectomy for palmar

hyperhidrosis.

 

Lindquist C, Fedorcsak I, Steig PE.

 

Department of Neurosurgery, Karolinska Institute, Stockholm, Sweden.

 

High upper thoracic sympathectomy using microsurgical techniques aided by

electrical stimulation of the sympathetic chain is described. Use of the

microscope facilitates identification and dissection of the sympathetic chain

and minimizes the risk of pleural damage. Electrical stimulation of the

sympathetic chain establishes the correct functional level for surgical

excision. At the correct level, the threshold for piloerection, sudomotor

response, and decrease in blood flow of the ipsilateral hand to electrical

stimulation was minimal, and a six-fold increase in stimulus current causing

current spread was required to dilate the ipsilateral pupil. After

identification of the proper level, surgical excision can be done without

risking postoperative Horner's syndrome. Excision of the appropriate ganglia and

intervening sympathetic chain with placement of surgical clips on the proximal

and distal nerve stumps provides tissue for histological analysis, decreases the

opportunity for regeneration, and facilitates localization on postoperative

x-rays.

 

PMID: 2927620 [PubMed - indexed for MEDLINE]

 

 

 

363: Pneumologie  1989 Feb;43(2):107-8

 

[Thoracoscopic sympathectomy in hyperhidrosis]

 

[Article in German]

 

Toomes H, Linder A.

 

The effectivity of sympathectomy performed via thoracoscopy as initiated by Kux,

has been confirmed by examining two cases reported here.

 

PMID: 2717549 [PubMed - indexed for MEDLINE]

 

 

 

364: Ann R Coll Surg Engl  1989 Jan;71(1):70-1

 

Transthoracic sympathectomy for palmar hyperhidrosis in children under 16 years

of age.

 

Law NW, Ellis H.

 

Professorial Surgical Unit, Westminster Hospital, London.

 

Palmar hyperhidrosis can be a disabling condition in children. We report the

results of transthoracic sympathectomy in 18 children aged 16 years or under.

Follow-up, 1 to 11 years after surgery, revealed a high incidence of late

sequelae, but these were not significant when compared to the primary condition.

Transthoracic sympathectomy is recommended for children with severe palmar

hyperhidrosis.

 

PMID: 2923427 [PubMed - indexed for MEDLINE]

 

 

 

365: Practitioner  1988 Sep 8;232(1454 ( Pt 1)):953-6

 

Comment in:

 Practitioner. 1989 Jun 22;233(1471):895.

 

Treating hyperhidrosis.

 

Grice K.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 3076945 [PubMed - indexed for MEDLINE]

 

 

 

366: Br Med J (Clin Res Ed)  1988 May 14;296(6633):1345

 

Treating hyperhidrosis.

 

Simpson N.

 

Glasgow Royal Infirmary.

 

PMID: 3134977 [PubMed - indexed for MEDLINE]

 

 

 

367: Surgery  1988 May;103(5):568-72

 

Dorsal sympathectomy for hyperhidrosis--the posterior paravertebral approach.

 

Golueke PJ, Garrett WV, Thompson JE, Talkington CM, Smith BL.

 

Department of Surgery, Baylor University Medical Center, Dallas, Texas.

 

Definitive therapy for hyperhidrosis is sympathectomy. The authors have used a

posterior approach to perform 36 dorsal sympathectomies for upper extremity

hyperhidrosis in 18 patients (12 female, 6 male). All 18 patients suffered from

excessive sweating of the upper extremity (17 palmar, 1 axillary) that caused

significant psychological and occupational problems. Eleven patients (61.1%) had

lower extremity involvement as well. For all 18 patients conservative medical

treatment had failed. Bilateral operations were performed, via a posterior

extrapleural approach, through the bed of the third rib. All 36 limbs were

relieved of excess sweating. There were no deaths and only two minor wound

complications. In no patient did Horner's syndrome develop. Long-term follow-up

did not reveal any recurrence of hyperhidrosis. Two patients did complain of

compensatory hyperhidrosis of the lower extremities. Dorsal sympathectomy was

effective in all of the patients with upper extremity hyperhidrosis in this

series. The posterior approach is technically simple, allows simultaneous

bilateral operations, and is associated with only infrequent minor

complications.

 

PMID: 3363492 [PubMed - indexed for MEDLINE]

 

 

 

368: Neurosurgery  1988 Mar;22(3):600-4

 

New stereotactic technique for percutaneous thermocoagulation upper thoracic

ganglionectomy in cases of palmar hyperhidrosis.

 

Chuang KS, Liou NH, Liu JC.

 

Department of Surgery, National Defense Medical Center, Taipei, Taiwan, Republic

of China.

 

To perform unilateral or bilateral upper thoracic ganglionectomy, we established

a three-dimensional system of coordinates for T2 and T3 ganglia. For this

purpose, the spatial relations were represented by drawings obtained from 50

Chinese cadavers. A simple stereotactic frame was constructed as an aid in

performing the procedure. Then, according to the established three-dimensional

system of coordinates, percutaneous thermocoagulation of both T2 and T3 ganglia

was performed on 10 patients (20 sides) with palmar hyperhidrosis, under local

anesthesia and fluoroscopic guidance at the posteroanterior projection.

Excellent relief of abnormal sweating in 19 of the 20 hands was achieved.

Partial relief was obtained in the remaining hand. No complication was observed

in our patients. The technique has been proved to be safe, effective, and

simpler than other methods now in use.

 

PMID: 3283596 [PubMed - indexed for MEDLINE]

 

 

 

369: Dig Dis Sci  1988 Feb;33(2):157-60

 

Effects of upper dorsal sympathectomy on esophageal motility in humans.

 

Soffer EE, Schneiderman J, Schwartz I, Halpern Z, Adar R, Weissberg D, Bar-Meir

S.

 

Department of Gastroenterology, Edith Wolfson Hospital, Holon, Israel.

 

To evaluate the role of the sympathetic nervous system in modulating esophageal

motility, esophageal manometry was performed on two groups of patients who

underwent upper dorsal sympathectomy for relief of palmar hyperhydrosis. In six

patients sympathectomy was done by the supraclavicular approach, with removal of

T2 and T3 ganglia. Manometry was performed before the operation and three weeks

after it. In seven other patients sympathectomy was done by the axillary

approach, with removal of T2-T4 ganglia. Manometry in this group was performed

28.4 +/- 22.4 months after the operation. Fifteen individuals with an intact

sympathetic system served as controls. Manometric parameters evaluated were

esophageal contraction amplitude and duration and lower esophageal sphincter

pressure. The difference between the results obtained in the pre- and

postoperative periods in the first group was not statistically significant. The

differences between the two patient groups and between the patient groups and

the control group were not statistically significant either. We conclude that

upper dorsal sympathectomy does not affect esophageal motility in man.

 

PMID: 3338363 [PubMed - indexed for MEDLINE]

 

 

 

370: Ann Dermatol Venereol  1988;115(10):1063-6

 

[Treatment of hyperhidrosis]

 

[Article in French]

 

Lazareth I, Priollet P.

 

Service de Pathologie vasculaire et de Medecine interne, Hopital Broussais,

Paris.

 

PMID: 3232914 [PubMed - indexed for MEDLINE]

 

 

 

371: ORL J Otorhinolaryngol Relat Spec  1988;50(4):246-50

 

Nasal obstruction after cervical sympathectomy: Horner's syndrome revisited.

 

Whittet HB, Fisher EW.

 

Royal National Throat, Nose and Ear Hospital, London, UK.

 

Horner's syndrome (cervical sympathetic paralysis) typically includes ptosis,

miosis, enophthalmos and facial anhidrosis. However, the effect of sympathetic

denervation upon the nasal mucosa should be included as a prominent feature,

since nasal obstruction is often the most disabling sequel. The anatomical,

physiological, and historical basis is discussed and surgical management

suggested.

 

PMID: 3174078 [PubMed - indexed for MEDLINE]

 

 

 

372: Gaoxiong Yi Xue Ke Xue Za Zhi  1987 Nov;3(11):703-7

 

Long-term follow up of upper dorsal sympathetic ganglionectomy for palmar

hyperhidrosis--a scale of evaluation.

 

Howng SL, Loh JK.

 

PMID: 3482266 [PubMed - indexed for MEDLINE]

 

 

 

373: S Afr Med J  1987 Oct 17;72(8):538-9

 

Surgical management of patients with hyperhidrosis.

 

Cilliers PH.

 

Department of Surgery, University of the Orange Free State, Bloemfontein.

 

Eighteen patients with hyperhidrosis affecting different anatomical areas were

treated with a variety of surgical methods. Bilateral axillary gland excision is

an appropriate and cosmetically acceptable method of treating axillary

hyperhidrosis (11 patients). Bilateral supraclavicular cervical sympathectomy

was performed for excessive sweating of the hands (7 patients). Bilateral lumbar

sympathectomy was necessary in only 3 patients with excessive sweating of the

feet. When perineal hyperhidrosis is present, the first lumbar ganglia must be

excised. Transaxillary, transpleural sympathectomy, removing the first to fourth

thoracic ganglia, is successful in treating failures of sweat gland excision or

troublesome sweating of hands and axillae.

 

PMID: 3672271 [PubMed - indexed for MEDLINE]

 

 

 

374: Clin Physiol  1987 Oct;7(5):403-9

 

A comparison between 133Xenon washout technique and Laser Doppler flowmetry in

the measurement of local vasoconstrictor effects on the microcirculation in

subcutaneous tissue and skin.

 

Kastrup J, Bulow J, Lassen NA.

 

Department of Clinical Physiology and Nuclear Medicine, Bispebjerg Hospital,

Copenhagen, Denmark.

 

Changes in skin blood flow measured by Laser Doppler flowmetry and changes in

subcutaneous blood flow measured by 133Xenon washout technique were compared

during activation of the local sympathetic mediated veno-arteriolar

vasoconstrictor reflex by lowering the area of investigation below heart level.

The measurements were performed in tissue with and without sympathetic

innervation. In five subjects, who all had been cervically sympathectomized for

manual hyperhidrosis, the Laser Doppler and 133Xenon blood flow measurements

were performed simultaneously on the sympathetically denervated forearm, and on

the calf with preserved sympathetic nerve supply. The Laser Doppler method

registered a 23% reduction in skin blood flow during lowering of the extremities

independently of the sympathetic nerve supply to the skin. The 133Xenon method

recorded a 44% decrease in blood flow in innervated and unchanged blood flow in

denervated subcutaneous tissue during lowering of the extremities. Our results

indicate that the Laser Doppler method and 133Xenon method are not comparable,

and that the Laser Doppler method is not useful in measuring local sympathetic

mediated blood flow changes.

 

PMID: 2959430 [PubMed - indexed for MEDLINE]

 

 

 

375: Acta Radiol  1987 Sep-Oct;28(5):511-5

 

Percutaneous phenol block of the upper thoracic sympathetic chain with computed

tomography guidance. A new technique.

 

Dondelinger RF, Kurdziel JC.

 

Department of Radiology, Centre Hospitalier, Luxembourg.

 

Twenty-one percutaneous neurolyses of the upper thoracic sympathetic chain were

performed in 12 patients with CT guidance by a single injection of 1 to 3 ml of

phenol at the level of Th3. Results were assessed after a follow-up period

varying from 4 to 33 months. Three patients with hyperhidrosis had immediate and

complete disappearance of symptoms, but only one patient remained dry. In 7/14

procedures done for Raynaud's disease symptoms disappeared or diminished. These

long term results are competitive with surgery. Three transitory Horner

syndromes and one pneumothorax occurred.

 

PMID: 2960340 [PubMed - indexed for MEDLINE]

 

 

 

376: Arch Dermatol  1987 Jul;123(7):883-4

 

Treatment of hyperhidrosis.

 

Dobson RL.

 

Publication Types:

Editorial

 

PMID: 3606165 [PubMed - indexed for MEDLINE]

 

 

 

377: Arch Dermatol  1987 Jul;123(7):925-9

 

Emotional eccrine sweating. A heritable disorder.

 

James WD, Schoomaker EB, Rodman OG.

 

A family with hereditary emotional hyperhidrosis is described. The inheritance

pattern is autosomal dominant. A simple quantitative palmar sweat test was used

to objectively confirm historical data. Of two family members tested, both had a

marked decrease in palmar sweat secretion during administration of diltiazem, a

calcium-channel blocker. Additional studies in a large group of patients are

needed to extend this observation.

 

PMID: 3606171 [PubMed - indexed for MEDLINE]

 

 

 

378: Br J Surg  1987 Jul;74(7):651

 

Upper dorsal sympathectomy for palmar hyperhidrosis.

 

Conlon KC, Keaveny TV.

 

PMID: 3620881 [PubMed - indexed for MEDLINE]

 

 

 

379: Hawaii Med J  1987 Jul;46(7):238, 259-60

 

Erratum in:

 Hawaii Med J 1987 Oct;46(10):372. Tsuhima WT[corrected to Tsushima WT]

 

Behavioral treatment of palmar hyperhidrosis.

 

Tsushima WT, Glamb RW, Pang DB, Tsuhima WT.

 

PMID: 3305418 [PubMed - indexed for MEDLINE]

 

 

 

380: Ann Surg  1986 Dec;204(6):715-8

 

Cardiovascular changes after bilateral upper dorsal sympathectomy. Short- and

long-term effects.

 

Papa MZ, Bass A, Schneiderman J, Drori Y, Tucker E, Adar R.

 

The effect of bilateral upper dorsal sympathectomy (UDS) on cardiac function was

investigated in two groups of young healthy patients who underwent bilateral

excision of T2 and T3 ganglia for palmar hyperhidrosis. In ten patients

echocardiography of left ventricular function (LVF) was performed before

operation and 2 weeks after operation. Electrocardiograms (ECG) were done before

operation, during operation immediately after sectioning each sympathetic chain,

and at 2 weeks after operation. The mean pulse rate decreased significantly in

patients after they underwent bilateral UDS. There were no clinical arrhythmias

or changes in LVF in any patient. Submaximal exercise testing and ECG tracings

done at rest and after effort were obtained for 29 patients before undergoing

bilateral UDS, 30 days after operation, and 1-3 more times within a 2-year

postoperative period. Pulse rates taken at rest and after effort were

significantly lower than those taken after operation, and the blood pressure

response to exercise was blunted. ECG tracings showed a significant change in

the electrical frontal plane axis and shortening of the QTc interval. These

changes were evident 30 days after operation and persisted for 2 years. In

conclusion, bilateral UDS has no overt arrhythmogenic effect in the young,

healthy heart and its beta-blocker-like effect persists for at least 2 years.

 

PMID: 3789841 [PubMed - indexed for MEDLINE]

 

 

 

381: Mayo Clin Proc  1986 Dec;61(12):951-6

 

Treatment of primary hyperhidrosis.

 

White JW Jr.

 

Primary hyperhidrosis is a physically and emotionally distressing condition.

Physicians should be aware of the various treatment modalities available for

controlling or reducing the profuse sweating, which involves mainly the palms,

soles, and axillas. The simplest methods, such as topical application of

aluminum chloride, should be attempted first. If topical medications are

ineffective, iontophoresis may provide relief, especially in patients with

plantar or palmar involvement. When patients are unresponsive to other treatment

options, surgical intervention may be warranted-excision of sweat glands in

patients with axillary hyperhidrosis and upper thoracic sympathectomy in those

with palmar involvement. Although excellent results have been reported,

complications and resumption of sweating have occurred.

 

PMID: 3095597 [PubMed - indexed for MEDLINE]

 

 

 

382: Clin Exp Dermatol  1986 Nov;11(6):543-52

 

Characterization and quantification of sweating in a systemic hyperhidrotic

patient.

 

Kenney MJ, Owen MD, Wall PT, Gisolfi CV.

 

PMID: 3665143 [PubMed - indexed for MEDLINE]

 

 

 

383: Ann R Coll Surg Engl  1986 Sep;68(5):292-3

 

Endoscopic thoracic sympathectomy in the treatment of upper limb hyperhydrosis.

 

Publication Types:

Letter

 

PMID: 3789630 [PubMed - indexed for MEDLINE]

 

 

 

384: Br J Dermatol  1986 Jul;115(1):81-4

 

The surgical treatment of upper limb hyperhidrosis.

 

Malone PS, Cameron AE, Rennie JA.

 

Primary hyperhidrosis is a common and poorly understood condition. Surgical

thoracic sympathectomy, either by the cervical or transaxillary route, entails

major surgery, so there is a tendency to offer this only to those most severely

affected. Endoscopic thoracic sympathectomy is a simple, safe and effective

procedure. The technique and results are described and it is recommended as the

appropriate procedure for treating upper limb hyperhidrosis, including localized

axillary sweating.

 

PMID: 3730280 [PubMed - indexed for MEDLINE]

 

 

 

385: Br J Hosp Med  1986 Feb;35(2):124-5

 

Lumbar sympathectomy.

 

Ellis H.

 

Lumbar sympathectomy is used in patients with threatened or early gangrene of

the toes where reconstructive arterial surgery is not possible--usually because

arteriography has demonstrated absence of a "run off" suitable for

endarteriectomy or a bypass graft. It may also be a supplement to reconstructive

surgery of the aorta or the common iliac arteries. It is indicated in

intractable Raynaud's disease affecting the feet and is particularly helpful in

severe hyperhidrosis of the feet. In many cases the procedure can be performed

nonoperatively by chemical sympathectomy using an injection of aqueous phenol

into the lumbar chain.

 

PMID: 3730665 [PubMed - indexed for MEDLINE]

 

 

 

386: Acta Neurochir (Wien)  1986;81(3-4):128-31

 

Hyperhidrosis and its surgical treatment.

 

Gruszkiewicz J, Doron Y, Guilburd JN, Zaaroor M.

 

111 sections of high thoracic sympathectomies in 60 cases suffering from primary

palmar hyperhidrosis are reported. Surgical results and postoperative

complications are discussed in detail. Complications were few in number and were

of a transitory nature. No mortality occurred in our series. Various surgical

and nonsurgical procedures of treatment are reviewed. Surgical intervention

remains the treatment of choice in essential idiopathic hyperhidrosis.

 

PMID: 3751696 [PubMed - indexed for MEDLINE]

 

 

 

387: Br J Hosp Med  1986 Jan;35(1):50-1

 

Transthoracic sympathectomy.

 

Ellis H.

 

Excision of the upper thoracic sympathetic chain can be performed effectively

and safely by a transthoracic approach. The most valuable indication is for

severe idiopathic hyperhidrosis of the hands for which it produces a most

satisfactory and lasting relief. It is also indicated for severe Raynaud's

phenomenon that does not respond to conservative measures but here there is a

tendency to progressive relapse following surgery so that only about half the

 

patients show improvement several years later.

 

PMID: 3955290 [PubMed - indexed for MEDLINE]

 

 

 

388: Cleve Clin Q  1986 Spring;53(1):83-8

 

Essential hyperhidrosis. Current therapy.

 

Tabet JC, Bay JW, Magdinec M.

 

PMID: 3708849 [PubMed - indexed for MEDLINE]

 

 

 

389: Am J Surg  1985 Dec;150(6):762-6

 

Upper dorsal sympathectomy.

 

Manart FD, Sadler TR Jr, Schmitt EA, Rainer WG.

 

Over a 20 year period, 60 patients underwent 76 procedures for upper dorsal

sympathectomy, usually with a transaxillary approach but occasionally with an

anterior approach. Procedures in male patients and in those that were carried

out on the right side were most frequent. There were few simultaneous

procedures. The extent of sympathectomy included resection of the lower half of

the stellate ganglion through the fourth thoracic ganglion. The results were

satisfying for patients with vasospastic disorders and hyperhidrosis and quite

acceptable for those with causalgia and vaso-occlusive disorders. Complication

rates and the incidence of postoperative Horner's syndrome were low. There were

prominent differences in results among the various age groups. In addition,

female patients and those with bilateral procedures had less favorable results.

Factors that did not appear to affect results included technique of surgical

approach, extent of sympathectomy, presence of Horner's syndrome, or the

addition of other procedures. Current indications for upper dorsal sympathectomy

include cases of Raynaud's and Buerger's diseases refractory to drug therapy,

causalgia, vaso-occlusive disorders, and hyperhidrosis.

 

PMID: 4073370 [PubMed - indexed for MEDLINE]

 

 

 

390: J R Coll Surg Edinb  1985 Aug;30(4):221-3

 

Transthoracic endoscopic sympathectomy.

 

Milewski PJ, Hodgson SP, Higham A.

 

PMID: 4057135 [PubMed - indexed for MEDLINE]

 

 

 

391: Tex Med  1985 May;81(5):49-53

 

Palmar hyperhidrosis.

 

Haar FL, Rosen T, Fayle RW.

 

PMID: 4002174 [PubMed - indexed for MEDLINE]

 

 

 

392: Acta Neurochir (Wien)  1985;74(3-4):152-3

 

Thoracodorsal sympathectomy en bloc. Anatomical variations versus results.

 

Lemmens HA, Drukker J.

 

PMID: 3984793 [PubMed - indexed for MEDLINE]

 

 

 

393: Acta Neurochir (Wien)  1985;74(3-4):153-4

 

Treatment of sweating and blushing by endoscopic surgery.

 

Wittmoser R.

 

PMID: 3984794 [PubMed - indexed for MEDLINE]

 

 

 

394: Acta Neurochir (Wien)  1985;74(3-4):154-5

 

"Gestalt" therapy in blushing and sweating.

 

Siemens H.

 

PMID: 3984795 [PubMed - indexed for MEDLINE]

 

 

 

395: Neurosurgery  1984 Dec;15(6):811-4

 

Percutaneous radiofrequency upper thoracic sympathectomy: a new technique.

 

Wilkinson HA.

 

The author describes a new technique for performing unilateral or bilateral

upper thoracic sympathectomy safely, effectively, and more easily than by any of

the surgical methods now in use. The technique described is one of percutaneous

radiofrequency sympathectomy, which is usually done on a day surgery or

outpatient surgery basis. The technique has been effective and well tolerated in

a small group of patients.

 

PMID: 6514152 [PubMed - indexed for MEDLINE]

 

 

 

396: N Engl J Med  1984 Jul 5;311(1):34-6

 

Radiofrequency percutaneous upper-thoracic sympathectomy. Technique and review

of indications.

 

Wilkinson HA.

 

PMID: 6727962 [PubMed - indexed for MEDLINE]

 

 

 

397: J R Coll Surg Edinb  1984 May;29(3):162-6

 

Modified supraclavicular approach for upper thoracic sympathectomy.

 

Soliman SM.

 

PMID: 6747921 [PubMed - indexed for MEDLINE]

 

 

 

398: Hautarzt  1984 Mar;35(3):142-7

 

[Tap water iontophoresis in the treatment of hyperhidrosis of the hands and

feet]

 

[Article in German]

 

Holzle E, Pauli M, Braun-Falco O.

 

Seven patients with hyperhidrosis of the palms or soles resistant to topical

application of aluminum chloride solution were treated successfully with tap

water iontophoresis. After an average of 10 or 11 treatments 80% sweating

suppression was found on palms and 74% suppression on soles. As side effects of

treatment discomfort and transient skin irritation were observed depending on

the amperage used. The effect lasts up to several weeks; however, maintenance

treatment on an individual schedule is required.

 

PMID: 6715169 [PubMed - indexed for MEDLINE]

 

 

 

399: J Vasc Surg  1984 Jan;1(1):202-14

 

Current status of thoracic dorsal sympathectomy.

 

Welch E, Geary J.

 

This article summarizes over 20 years of experience (1962 to 1982) with cervical

sympathectomy (thoracic dorsal sympathectomy) in 46 patients undergoing 68

sympathectomies. All operations were performed through an anterior

supraclavicular approach. Indications for surgery were intractable Raynaud's

disease (26 patients), atherosclerotic obliterative arterial disease (five),

causalgia (five), posttraumatic sympathetic dystrophy (seven), collagen vascular

disorders (eight), hyperhidrosis (12), occupational-related digital thrombosis

(four), and thrombosis secondary to intra-arterial injection (one). The

incidence of complications and side effects, both temporary and permanent,

including Horner's syndrome, is reviewed in detail. Particular reference is made

to the various surgical techniques of managing the stellate ganglion; four

patients had two-third to three-fourth resection of the stellate ganglion down

to and including the T-3 thoracic ganglion, two had preservation of the stellate

ganglion and resection of the T-2 through T-4 ganglia, seven had excision of the

entire stellate ganglion down to and including the T-4 ganglion, seven had

resection of the lower third of the stellate ganglion down to and including the

T-4 ganglion, and 48 had removal of the lower half of the stellate ganglion down

to and including the T-3 ganglion. The study reviews the literature germane to

anatomic considerations and suggests revisions in current texts and atlases. By

retrospective analysis of the records and a follow-up questionnaire, which

provided an 86% follow-up (average 8.4 years), the paper points to the

distinctive clinical characteristics of the different groups within the

population undergoing the operation and provides guidelines for patient

selection and conclusions on the place for this operation in the management of

vascular diseases involving the upper extremity.

 

PMID: 6481864 [PubMed - indexed for MEDLINE]

 

 

 

400: Arch Surg  1983 Sep;118(9):1065-7

 

Surgical treatment of primary hyperhidrosis. A report of 42 cases.

 

Bogokowsky H, Slutzki S, Bacalu L, Abramsohn R, Negri M.

 

Forty-two patients suffering from primary hyperhidrosis underwent upper dorsal

sympathectomy using the supraclavicular approach. The postoperative course and

results were devoid of complications. All the patients except one were satisfied

with the results of surgery, which greatly improved the quality of their lives.

 

PMID: 6615216 [PubMed - indexed for MEDLINE]

 

 

 

401: Ugeskr Laeger  1983 Aug 15;145(33):2536-8

 

[Treatment of sweating]

 

[Article in Danish]

 

Christensen JD.

 

PMID: 6612879 [PubMed - indexed for MEDLINE]

 

 

 

402: Anasth Intensivther Notfallmed  1983 Aug;18(4):174-6

 

[Endobronchial ventilation in transthoracic endoscopic sympathectomy]

 

[Article in German]

 

Eilenberger K, Lackner F, Funovics J, Porges P.

 

Thoracic endoscopic sympathectomy (TES) is a short surgical procedure used for

the treatment of axillary and palmar hyperhydrosis. It involves creation of

tension pneumothorax, lateral and head-up position and necessitates minimal lung

excursions during breathing, so that a special anaesthetic technique is

required. In six otherwise healthy patients an endobronchial double lumen tube

was used for one-lung ventilation with intravenous anaesthesia and muscular

relaxation, and circulatory response, FE CO2 and blood gases were monitored in

order to compare this anaesthetic technique to conventional endotracheal

intubation in previous patients. Some difficulties with inserting and securing

the double lumen tube were encountered, but were far outweighed by the

advantages of stable circulation, physiological blood gas values and easy access

to a calm surgical field.

 

Publication Types:

Clinical Trial

Controlled Clinical Trial

 

PMID: 6638418 [PubMed - indexed for MEDLINE]

 

 

 

403: Harefuah  1983 Jun;104(11-12):533-4

 

[Palmar hyperhidrosis--surgical treatment]

 

[Article in Hebrew]

 

Mozes M.

 

Publication Types:

Editorial

 

PMID: 6680716 [PubMed - indexed for MEDLINE]

 

 

 

404: J Auton Nerv Syst  1983 May;8(1):33-43

 

Autonomic dysfunction in palmar hyperhidrosis.

 

Shih CJ, Wu JJ, Lin MT.

 

The autonomic (including sudomotor, baroreceptor, and vasomotor) functions were

assessed in 3 groups of individuals, comprising normal, hyperhidrotic, and

denervated subjects. The normal group had no palmar hyperhidrosis, with intact

T2-3 ganglia, the hyperhidrotic group had palmar hyperhidrosis with intact T2-3

ganglia, and the denervated group had palmar hyperhidrosis treated with T2-3

ganglionectomy. Compared with both the normal and hyperhidrotic subjects, the

denervated subjects had a much smaller sweating response of both the forehead,

the upper chest region and the upper extremities, and a much greater sweating

response of both the lateral lumbar and ventral thigh regions in response to

body exercise. In addition, cardiovascular responses to either the Valsalva

manoeuver, face immersion, or finger immersion were evaluated in these groups of

subjects. When compared with those of either the normal or the denervated

subjects, the hyperhidrotic subjects had less reflex bradycardia in response to

either Valsalva manoeuver or face immersion. In contrast, when compared with

those of either the normal or the denervated subjects, the hyperhidrotic

subjects had a higher degree of cutaneous vasoconstriction in response to finger

(or cold) immersion. The data indicate that the sympathetic fibers passing

through the T2-3 ganglia play an important role in the elaboration or modulation

of autonomic function elsewhere. Probably, the hyperhidrotic subjects have an

over-functioning of the sympathetic nervous fibers which pass through the T2-3

ganglia, which leads to autonomic dysfunction. The autonomic dysfunctions

observed in the hyperhidrotic subjects could be eliminated after the

interruption of the excessive sympathetic activities passing through the T2-3

ganglia level. A preliminary report of this work was delivered at the 15th

Congress of the Pan-Pacific Surgical Association, January 12-18, 1980 and the

12th World Congress of Neurology, September 20-25, 1981.

 

PMID: 6875200 [PubMed - indexed for MEDLINE]

 

 

 

405: World J Surg  1983 May;7(3):437-9

 

Axillary transpleural sympathectomy: indication, technique, and results.

 

Linder F, Jenal G, Assmus H.

 

PMID: 6880233 [PubMed - indexed for MEDLINE]

 

 

 

406: J R Coll Surg Edinb  1983 Mar;28(2):116-20

 

The surgical treatment of associated axillary and palmar hyperhidrosis.

 

Kenawi MM, El Mofty M, Wishahy AH.

 

PMID: 6864604 [PubMed - indexed for MEDLINE]

 

 

 

407: Br Med J (Clin Res Ed)  1983 Feb 19;286(6365):580-1

 

Excessive sweating of the palms and armpits.

 

Savin JA.

 

Publication Types:

Editorial

 

PMID: 6402154 [PubMed - indexed for MEDLINE]

 

 

 

408: Isr J Med Sci  1983 Feb;19(2):112-5

 

Upper dorsal sympathectomy for palmar hyperhidrosis.

 

Bass A, Inovrotzlavski S, Adar R.

 

The treatment results in 133 patients who underwent bilateral upper dorsal

sympathectomy (BUDS) for palmar hyperhidrosis (HH) are reported. Group 1 (67

patients) was followed for 5 to 10 yr (mean 7) and Group 2 (66 patients) was

followed for 1 to 4 yr (mean 2). Early results and complications, early and late

sequelae, late recurrence and patient satisfaction with the results of the

operation were analyzed. The immediate success rate was 98%, and late recurrence

of HH was noted in 5.3% of the patients. The incidence of technical

complications was lower in Group 2 than in Group 1, otherwise both groups were

similar. Persistent, severe Horner's syndrome was present in only one patient at

late follow-up. Troublesome compensatory HH persisted in one-third of the

patients. Overall patient satisfaction was good, and only 10 patients regretted

having undergone the operation. BUDS appears to be the best solution for severe

palmar HH in properly selected patients.

 

PMID: 6841033 [PubMed - indexed for MEDLINE]

 

 

 

409: Annu Rev Med  1983;34:429-52

 

Sweating and its disorders.

 

Quinton PM.

 

Eccrine sweat is produced by millions of miniscule glands buried in the skin.

Eccrine sweating from the general body surface is an extremely important

function in human thermoregulation; disturbances either in the control of

sweating activity or in the glands themselves can result in problems ranging

from minor social embarrassment to fatal hyperpyrexia. A general review of the

function and control of normal sweating precedes an overview of sweating

abnormalities.

 

Publication Types:

Review

 

PMID: 6344770 [PubMed - indexed for MEDLINE]

 

 

 

410: Duodecim  1983;99(2):158-60

 

[Treatment of hyperhidrosis]

 

[Article in Finnish]

 

Hannuksela M.

 

Publication Types:

Review

 

PMID: 6347638 [PubMed - indexed for MEDLINE]

 

 

 

411: Minerva Chir  1982 Sep 15;37(17):1369-72

 

[Complications following thoracic gangliectomy. Analysis of cases]

 

[Article in Italian]

 

Giordanengo F, Odero A, Mingazzini P, Soleri V.

 

PMID: 7145146 [PubMed - indexed for MEDLINE]

 

 

 

412: World J Surg  1982 Jul;6(4):458-63

 

Transaxillary thoracic sympathectomy for primary hyperhidrosis of the upper

limbs.

 

Sternberg A, Brickman S, Kott I, Reiss R.

 

PMID: 7123983 [PubMed - indexed for MEDLINE]

 

 

 

413: Br J Surg  1982 Jun;69 Suppl:S29-31

 

Transaxillary sympathectomy--is a one-stage bilateral procedure safe?

 

Campbell WB, Cooper MJ, Sponsel WE, Baird RN, Peacock JH.

 

PMID: 7082970 [PubMed - indexed for MEDLINE]

 

 

 

414: Chirurgie  1982;108(2):197-201

 

[Sympathectomy in the palmar and plantar hyperhidrosis. Thirty seven operations]

 

[Article in French]

 

Bouchet A, Putot JP, Maurin T.

 

PMID: 7117025 [PubMed - indexed for MEDLINE]

 

 

 

415: Ir Med J  1982 Jan;75(1):20-1

 

Transthoracic electrocoagulation (T.T.E.C.)--a new and simple approach to upper

limb sympathectomy.

 

Malone PS, Duignan JP, Hederman WP.

 

PMID: 7085234 [PubMed - indexed for MEDLINE]

 

 

 

416: Harefuah  1981 Oct;101(7-8):166-7

 

[Surgical treatment of primary hyperhidrosis]

 

[Article in Hebrew]

 

Bogokowsky H, Abramsohn R, Bacalu L, Negri M.

 

PMID: 7333547 [PubMed - indexed for MEDLINE]

 

 

 

417: Przegl Dermatol  1981 Sep-Dec;68(5-6):593-7

 

[Surgical treatment of hyperhidrosis of the hands]

 

[Article in Polish]

 

Smolarek F, Olewinski J, Plachta H.

 

PMID: 7347413 [PubMed - indexed for MEDLINE]

 

 

 

418: Psychosomatics  1981 Jun;22(6):536-8

 

Treatment of essential hyperhidrosis by psychotherapy.

 

Lerer B, Jacobowitz J.

 

PMID: 7255644 [PubMed - indexed for MEDLINE]

 

 

 

419: Anaesthesist  1980 Nov;29(11):613-5

 

[Choice of anaesthesia technique in thoracic endoscopic sympathectomy (author's

transl)]

 

[Article in German]

 

Mauritz W, Czech K, Funovics J, Lackner F, Porges P, Schemper M.

 

Thoracic endoscopic sympathectomy (TES) is a short surgical procedure used for

the treatment of palmar and axillary hyperhidrosis. It involves pneumothorax,

the lateral and head up position, and necessitates minimal chest excursions

during breathing, so that a special type of anaesthesia is required. In 13

patients two different methods were compared and blood gas analysis as well as

circulatory parameters were studied. We therefore propose an anaesthetic method

using controlled mechanical ventilation; relaxation; intravenous anaesthesia; at

least 1 1 fluid replacement; and careful monitoring.

 

Publication Types:

Clinical Trial

Randomized Controlled Trial

 

PMID: 7457801 [PubMed - indexed for MEDLINE]

 

 

 

420: J Neurosurg  1980 Nov;53(5):684-9

 

Effects of cholinomimetic drugs on sudomotor, metabolic, respiratory, vasomotor,

and temperature response in palmar hyperhidrosis.

 

Shih CJ, Lin MT.

 

The effects of cholinomimetic drugs such as mecholyl (methacholine) and

pilocarpine on autonomic functions (including sudomotor, metabolic, respiratory,

vasomotor, and temperature responses) were assessed at room temperature (24

degrees C) in three groups of individuals, including normal, hyperhidrotic, and

denervated subjects. The normal group had no palmar hyperhidrosis, with intact

T2-3 ganglia, the hyperhidrotic group had palmar hyperhidrosis with intact T2-3

ganglia, and the denervated group had palmar hyperhidrosis treated with T2-3

ganglionectomy. Subcutaneous administration of mecholyl and pilocarpine each

produced a fall in oral temperature in the normal group. The hypothermia was

brought about by a decrease in metabolic rate, an increase in local sweating

rate (mainly of the upper limb and trunk), and an increase in cutaneous

circulation (estimated by an increase in the upper limb and trunk skin

temperatures). The autonomic functions induced by these cholinomimetic drugs

were antagonized by pretreatment with atropine sulfate (an antagonist of

cholinergic receptors). Moreover, the hypothermia induced by mecholyl or

pilocarpine was greatly reduced in the hyperhidrotic group. The reduction in the

cholinomimetic-induced hypothermia in the hyperhidrotic group was due to the

reduced sudomotor and metabolic responses after the injections of these

cholinomimetic drugs, as compared to those of the normal group. However, neither

the excessive sweating of the palms nor the reduced cholinergic responses in the

hyperhidrotic group was observed after T2-3 ganglionectomy. The data indicate

that the T2-3 ganglia play a role in the elaboration or modulation of the

sudomotor and metabolic responses induced by activation of certain cholinergic

receptors in humans.

 

PMID: 7431077 [PubMed - indexed for MEDLINE]

 

 

 

421: Lakartidningen  1980 May 21;77(21):1999-2000

 

[Quality of life and hyperhidrosis]

 

[Article in Swedish]

 

Mindus P.

 

PMID: 7401748 [PubMed - indexed for MEDLINE]

 

 

 

422: Ugeskr Laeger  1980 May 5;142(19):1199-201

 

[Surgical treatment of axillary hyperhidrosis. A comparison between 3 surgical

methods]

 

[Article in Danish]

 

Sorensen U.

 

PMID: 7404696 [PubMed - indexed for MEDLINE]

 

 

 

423: J Pediatr Surg  1980 Apr;15(2):172-4

 

Palmar primary hyperhidrosis in children.

 

O'Donoghue G, Finn D, Brady MP.

 

Palmar Primary Hyperhidrosis, though an uncommon problem in the paediatric age

group, is an unpleasant and socially disabling one for the affected child.

Although the condition occurring in adults has been extensively documented,

little, if any, attention has been given to the problem in children. We describe

the clinical presentation of four such patients who presented in our unit over

the past 4 yr. All had an upper dorsal sympathectomy performed with excellent

results.

 

PMID: 7373494 [PubMed - indexed for MEDLINE]

 

 

 

424: Int J Psychiatry Med  1980-81;10(1):59-67

 

Personality features in essential hyperhidrosis.

 

Lerer B, Jacobowitz J, Wahba A.

 

PMID: 7380618 [PubMed - indexed for MEDLINE]

 

 

 

425: Z Arztl Fortbild (Jena)  1980;74(2):60-1

 

[Excessive hyperhidrosis and possibilities of surgical therapy]

 

[Article in German]

 

Strauchmann G, Willenberg E.

 

PMID: 7415236 [PubMed - indexed for MEDLINE]

 

 

 

426: Br Med J  1979 Nov 10;2(6199):1225

 

Treatment of hyperhidrosis.

 

Bedford B, McKinnon EV.

 

Publication Types:

Letter

 

PMID: 519387 [PubMed - indexed for MEDLINE]

 

 

 

427: Pediatrics  1979 Nov;64(5):698

 

Excessive sweating in an apparently normal teenager.

 

Fan WJ, Cohen NM.

 

Publication Types:

Letter

 

PMID: 492848 [PubMed - indexed for MEDLINE]

 

 

 

428: Am Surg  1979 Sep;45(9):546-51

 

Transaxillary sympathectomy in the treatment of hyperhidrosis of the upper limb.

 

Ellis H.

 

Idiopathic (primary) hyperhidrosis is a common and distressing condition.

Excessive axillary sweating responds to local excision of the eccrine glands. In

severe cases, sympathectomy may be indicated to deal with hyperhidrosis of the

hands and feet. The surgical anatomy of transthoracic sympathectomy is

described.

 

PMID: 507560 [PubMed - indexed for MEDLINE]

 

 

 

429: J Neurosurg  1979 Sep;51(3):424-5

 

Compensatory sweating after upper dorsal sympathectomy.

 

Adar R.

 

Publication Types:

Letter

 

PMID: 469591 [PubMed - indexed for MEDLINE]

 

 

 

430: J Neurosurg  1979 Sep;51(3):425

 

Compensatory sweating after upper dorsal sympathectomy.

 

Shih GJ.

 

Publication Types:

Letter

 

PMID: 469592 [PubMed - indexed for MEDLINE]

 

 

 

431: Ann Ophthalmol  1979 Jul;11(7):1083-6

 

Ocular manifestations after upper dorsal sympathectomy.

 

Romano A, Kurchin A, Rudich R, Adar R.

 

Fifty patients underwent ophthalmologic examination before and after bilateral

upper dorsal sympathectomy performed for palmar hyperhidrosis. Postoperative

examination was done during the first week, at 3 to 4 weeks and at 6 to 12

months after the operation. Immediately after surgery there were 18 patients

with ptosis (6 severe) and 23 with miosis (12 severe). There were 19 patients

with excessive lacrimation and some degree of congestion of conjunctival blood

vessels was present in almost all patients. Uniocular decrease in tears was

present in 2 patients. Most of these manifestations decreased with passage of

time. At one year there remained only 3 patients with severe ptosis and 4 with

severe miosis. The results suggest that the classical anatomic explanation of

Horner's syndrome may require some modification.

 

PMID: 485002 [PubMed - indexed for MEDLINE]

 

 

 

432: J Cardiovasc Surg (Torino)  1979 May-Jun;20(3):283-8

 

The anatomy of the lumbar sympathetic trunks in man (with special reference to

the question of regeneration after sympathectomy).

 

Simeone FA.

 

Although possible to decentralize the sympathetic outflow to the leg, below the

knee, by resecting only the third lumbar sympathetic ganglion, the likelihood of

restoration of normal vasoconstrictor activity warrants a more extensive

resection to include at least the second and third lumbar ganglia, and

preferably the second, third, and fourth lumbar ganglia. When cross-over fibers

are suspected or demonstrated following unilateral sympathectomy, the

denervation should include the fourth and fifth lumbar ganglia. The first lumbar

ganglion should be spared at least unilaterally if interference with

reproductive function is to be avoided.

 

PMID: 447765 [PubMed - indexed for MEDLINE]

 

 

 

433: Med Hypotheses  1979 Mar;5(3):317-22

 

Hyperhidrosis and the sympatho-adrenal system.

 

Robertshaw D.

 

Some disorders in which excessive sweating, hyperhidrosis, is a symptom are also

characterized by increased sympatho-adrenal activity. Such disorders are

hypotension, hypoglycemia, pheochromocytoma and hyperthyroidism. Sweat glands

are controlled by a cholinergic innervation but can also be stimulated by

adrenergic agents whose effects can be blocked by both alpha- and beta-receptor

blocking drugs. An adrenergic innervation has also been demonstrated. There is

evidence that the adrenergic component of sweating particularly secretion of the

adrenal medulla, is responsible for the enhancement of sweating during exercise

but not for the hyperhidrosis present in these disorders since sweating in these

circumstances can be effectively blocked by cholinergic blocking compounds.

Cutaneous vasoconstriction due to elevated plasma catecholamines reduces the

rate of evaporation of sweat and allows sweat to accumulate on the skin. It is

suggested that in the case of hypotension and insulin hypoglycemia sweating

results from general sympathetic stimulation and that adrenal medullary hormones

are not an essential component of the response. Hyperhidrosis in

pheochromocytoma may be due to central activation of heat loss mechanisms

resulting from the passage of plasma catecholamines across the blood-brain

barrier combined with increased thermogenesis and cutaneous vasoconstriction.

The hyperhidrosis of hyperthyroidism is probably due to increased thermogenesis.

 

PMID: 459985 [PubMed - indexed for MEDLINE]

 

 

 

434: J Neurosurg  1979 Jan;50(1):88-94

 

Thermoregulatory sweating in palmar hyperhidrosis before and after upper

thoracic sympathectomy.

 

Shih CJ, Lin MT.

 

To assess thermoregulatory sweating in palmar hyperhidrosis, the authors

determined the responses of three groups of normal, hyperhidrotic, and

denervated subjects to a variety of ambient temperatures (TA's), 22 degrees, 28

degrees, and 41 degrees C. The normal group had no hyperhidrosis, with intact

T2-3 ganglia, the hyperhidrotic group had palm hyperhidrosis with intact T2-3

ganglia, and the denervated group had hyperhydrosis treated with T2-3

ganglionectomy. Both groups of hyperhidrotic and denervated subjects maintained

oral and mean skin temperatures within normal limits displayed by the normal

group over a wide range of TA's tested. The local sweating rate (LSR) of both

the palms and the soles of the feet in the hyperhidrotic group was decreased to

a minimal level by either the T2-3 ganglionectomy or the subcutaneous

administration of atropine sulfate. Furthermore, the denervated group had a

significantly lower LSR of both the forehead and the upper chest regions, but

showed a higher LSR or both the ventral thigh and the lateral lumbar regions at

a TA of 41 degrees C when compared to the LSR of either the normal or the

unoperated hyperhidrotic group. The data demonstrate that the surgical removal

of both the T-2 and the T-3 ganglia, although producing no alterations in the

thermal balance, does produce abnormalities in quantitative distribution of

thermoregulatory sweating in man.

 

PMID: 758384 [PubMed - indexed for MEDLINE]

 

 

 

435: Surg Neurol  1978 Nov;10(5):291-6

 

Thoracic sympathectomy for palmar hyperhidrosis: report of 457 cases.

 

Shih CJ, Wang YC.

 

A thoracic sympathetic ganglionectomy was performed on 457 patients with palmar

hyperhidrosis, resulting in a complete cessation of the excessive palmar

sweating but not a total abolition of the sweating of the upper extremity,

forehead, face, neck, upper chest and upper back. This procedure does not

produce a Horner's syndrome. The present data provide evidence that sympathetic

pathways for controlling sweating of the above-mentioned skin areas come mainly

through the second thoracic ganglion, and therefore from the spinal cord segment

below T1 in man.

 

PMID: 725736 [PubMed - indexed for MEDLINE]

 

 

 

436: JAMA  1978 Oct 6;240(15):1588

 

Gustatory sweating.

 

Schultz GT.

 

Publication Types:

Letter

 

PMID: 691144 [PubMed - indexed for MEDLINE]

 

 

 

437: Dermatol Monatsschr  1978 Oct;164(10):727-8

 

[Metal corrosion (rust) as a result of hyperhidrosis (author's transl)]

 

[Article in German]

 

Zschunke E.

 

PMID: 738492 [PubMed - indexed for MEDLINE]

 

 

 

438: Br Med J  1978 Aug 12;2(6135):503-4

 

Treatment of hyperhidrosis.

 

Publication Types:

Letter

 

PMID: 678946 [PubMed - indexed for MEDLINE]

 

 

 

439: Dtsch Med Wochenschr  1978 Jul 28;103(30):1198

 

[Hyperhidrosis]

 

[Article in German]

 

Brautigam W.

 

Publication Types:

Letter

 

PMID: 668559 [PubMed - indexed for MEDLINE]

 

 

 

440: Angiologia  1978 Jul-Aug;30(4):131-3

 

[Palm hyperhidrosis. 100 cases surgically treated by cervicodorsal

sympathectomy]

 

[Article in Spanish]

 

Galindo N, Osso J, Orti M, Conill C, Sainz de la Maza T.

 

PMID: 677524 [PubMed - indexed for MEDLINE]

 

 

 

441: Ann Dermatol Venereol  1978 May;105(5):555

 

[Surgical treatment for excessive sweating of the upper extremities]

 

[Article in French]

 

Bureau H, Magalon G, de Tadeo P, Tramier H.

 

PMID: 707949 [PubMed - indexed for MEDLINE]

 

 

 

442: Dtsch Med Wochenschr  1978 Apr 7;103(14):632

 

[Hyperhidrosis]

 

[Article in German]

 

Entzian W.

 

Publication Types:

Letter

 

PMID: 639699 [PubMed - indexed for MEDLINE]

 

 

 

443: Arch Surg  1978 Mar;113(3):264-6

 

Thoracic endoscopic sympathectomy in palmar and axillary hyperhidrosis.

 

Kux M.

 

An endoscopic technique is described for thoracic sympathectomy. After

establishment of a pneumothorax, the thoracoscope is introduced into the pleural

cavity. The telescope is equipped with a wire electrode, a grasping forceps, and

a suction coagulation probe for endoscopic electroresection of the sympathetic

trunk. In 63 patients, 124 endoscopic sympathectomies were performed. All

patients were relieved of sweating in the hands; 18.6% still had some

perspiration of the axilla. Side effects of thoracic sympathectomy were

compensatory and gustatory sweating that, in four patients, were more

embarrassing than the original form of hyperhidrosis. Fifty-five patients were

highly satisfied with the result of endoscopic sympathectomy, which is

considered the appropriate minor procedure for the treatment of upper limb

hyperhidrosis, causing minimal discomfort to the patient and almost invisible

scars.

 

PMID: 637691 [PubMed - indexed for MEDLINE]

 

 

 

444: Dtsch Med Wochenschr  1978 Feb 17;103(7):292

 

[Hyperhidrosis]

 

[Article in German]

 

von Eiff AW.

 

Publication Types:

Letter

 

PMID: 627189 [PubMed - indexed for MEDLINE]

 

 

 

445: Acta Chir Acad Sci Hung  1978;19(1):69-74

 

[Late results of thoracic sympathectomy in various diseases]

 

[Article in German]

 

Sebesteny M, Mogan I, Papp S, Szabo I, Soltesz L.

 

The late results of 171 thoracal sympathectomies performed on 142 patients in

the 20-year period 1952 to 1971 are described. Favourable results were achieved

in Raynaud's disease, obliterating endarteritis and other occlusive vascular

diseases, and also in hyperhidrosis.

 

PMID: 706955 [PubMed - indexed for MEDLINE]

 

 

 

446: AMB Rev Assoc Med Bras  1978 Jan;24(1):29-30

 

[Treatment of palmar hyperhidrosis by cervico-thoracic sympathectomy]

 

[Article in Portuguese]

 

Kauffman P, Cinelli M Jr, Wolosker M, Leao LE.

 

PMID: 305592 [PubMed - indexed for MEDLINE]

 

 

 

447: Clin Neurosurg  1978;25:637-50

 

Sympathectomy for vascular syndromes and hyperhidrosis of the upper extremities.

 

Dohn DF, Sava GM.

 

PMID: 710016 [PubMed - indexed for MEDLINE]

 

 

 

448: Psychosomatics  1977 Dec;18(5):28-31

 

Hyperhidrosis: a review of its psychological aspects.

 

Lerer B.

 

PMID: 605206 [PubMed - indexed for MEDLINE]

 

 

 

449: Angiology  1977 Nov;28(11):799-802

 

Phantom sweating.

 

Kurchin A, Mozes M, Walden R, Adar R.

 

Phantom sweating is a sensation in which the patient feels that sweat is about

to burst out of skin pores, but in which sweating never actually occurs. In a

series of 100 patients undergoing bilateral upper dorsal sympathectomy for

palmar hyperihidrosis, 82 patients were specifically questioned and 48 (59%)

reported phantom sweating. Phantom sweating started soon after the operation,

was triggered by the same stimuli that caused hyperhidrosis preoperatively,

lasted for a few seconds, and tended to diminish with time. In an average

follow-up of 18 months, the phenomenon disappeared in 11 patients (23%). Phantom

sweating is probably a symptom of residual sympathetic activity.

 

PMID: 911065 [PubMed - indexed for MEDLINE]

 

 

 

450: Arch Neurol  1977 Oct;34(10):619-23

 

Gustatory phenomena after upper dorsal sympathectomy.

 

Kurchin A, Adar R, Zweig A, Mozes M.

 

In a series of 100 bilateral upper dorsal sympathectomies performed for palmar

hyperhidrosis, gustatory sweating and other gustatory phenomena were reported by

68 of 93 patients (73%), followed up for an average of 1 1/2 years. These

gustatory phenomena were quite different from physiologic gustatory sweating: a

wide range of gustatory stimuli caused a variety of phenomena in varied

locations. There was a negative correlation between the incidence of these

phenomena and the occurrence of Horner's syndrome after sympathectomy. Analysis

of our observations, and of clinical and experimental work of others, leads to

the conclusion that gustatory phenomena after upper dorsal sympathectomy are the

result of preganglionic sympathetic regeneration or collateral sprouting with

aberrant synapses in the superior cervical ganglion.

 

PMID: 907534 [PubMed - indexed for MEDLINE]

 

 

 

451: Arch Phys Med Rehabil  1977 Oct;58(10):435-7

 

Reflex sweating in patients with spinal cord injury: a review.

 

Fast A.

 

Sweat glands derive their innervation from the sympathetic nervous system. The

spinal sympathetic structures that are located in the intermediolateral areas

extend from T1-L2 segments and are under the control of hypothalamic centers.

Cord transection abolishes the supraspinal control of sudorimotor function.

Since sympathetic innervation does not follow a clear segmental distribution,

normal sweating may be preserved at a higher or lower level than skin sensation.

Nonthermoregulatory reflex sweating is an indication of unchecked spinal cord

facilitation and is precipitated by afferent stimuli from bladder, rectum, and

various other sources. It is usually a manifestation of mass reflex or autonomic

crisis and occurs particularly in cervical or high thoracic lesions. Transection

below T8-T10 is not accompanied by reflex sweating. The phenomenon of thermal

relfex sweating is controversial. Although some aspects of nonthermoregulatory

reflex sweating are still unclear, proper immediate and continuing preventive

management will reduce the incidence of this and other autonomic manifestations.

Chemical sympathectomy should be a last resort in case of emergency or when the

source of facilitation cannot be ascertained.

 

Publication Types:

Review

 

PMID: 334108 [PubMed - indexed for MEDLINE]

 

 

 

452: Med J Aust  1977 Sep 10;2(11):348

 

Symposium on sweating.

 

Publication Types:

Editorial

 

PMID: 927260 [PubMed - indexed for MEDLINE]

 

 

 

453: Arch Neurol  1977 Sep;34(9):536-9

 

Hyperhydrosis in  paraplegia.

 

Kneisley LW.

 

A 20-year-old man suffered head, chest, and abdominal trauma in an auto accident

resulting in a traumatic dissecting aneurysm of the thoracic aorta. Hypotension

developed. The aneurysm was resected and replaced with a prosthetic graft.

Postoperatively, the patient was found to be paraplegic below T-9, areflexic and

anesthetic to pain and temperature, with preservation of vibration and position

senses. In the ensuing nine months, the patient regained considerable sensory

function in his lower extremities and had severe constant hyperhydrosis below

the T-9 dermatome. The exaggerated sweating was unaffected by temperature change

and anxiety. It was diminished by methantheline bromide treatment but never

abolished. The spinal cord lesion is postulated to be anterior horn cell loss,

with preservation of interneurons and intermediolateral gray columns.

Disinhibition of sympthetic circuits or sprouting of axons are proposed

mechanisms.

 

PMID: 889495 [PubMed - indexed for MEDLINE]

 

 

 

454: World J Surg  1977 Sep;1(5):667-74

 

Upper dorsal sympathectomy for palmar primary hyperhidrosis by the

supraclavicular approach.

 

Kurchin A, Zweig A, Adar R, Mozes M.

 

PMID: 602239 [PubMed - indexed for MEDLINE]

 

 

 

455: Br J Surg  1977 Aug;64(8):570-1

 

Surgical management of hyperhidrosis.

 

Keaveny TV, Fitzgerald PA, Donnelly C, Shanik GD.

 

Sixty-five patients with severe disabling hyperhidrosis were subjected to

operation. Eighty-nine sympathectomies and 42 axillary skin excisions were

performed to abolish sweating. Almost 90% of these patients were extremely

satisfied with the outcome of surgery which resulted in a change for the better

in their social and working lives. When conservative therapy fails, we recommend

these procedures, which often alleviate this most distressing symptom.

 

PMID: 890279 [PubMed - indexed for MEDLINE]

 

 

 

456: Ann Surg  1977 Jul;186(1):34-41

 

Palmar hyperhidrosis and its surgical treatment: a report of 100 cases.

 

Adar R, Kurchin A, Zweig A, Mozes M.

 

One hundred patients with primary palmar hyperhidrosis (HH) underwent bilateral

upper dorsal sympathectomy (UDS) by the supraclavicular approach. Pre-operative

epidemiological and clinical data are described. The immediate and late results,

as well as the complications and side-effects are detailed. Follow-up was

completed on 93 patients between four and 50 months after the operation (average

18 months). Of 93 patients, 91 had drying of the hands. In 58% some moisture

returned to the hands but in no case did the hyperhidrotic state recur.

Subjective patient evaluation was excellent or good in 83 patients (89%) and

only one patient (a technical failure) was completely dissatisfied. Reasons for

some degree of dissatisfaction with operation were mainly compensatory HH in non

denervated areas, and Horner's syndrome. Compensatory HH usually decreased with

passage of time and, permanent Horner's syndrome occurred in 8% of patients (4%

of procedures). Technical failure can be avoided by use of frozen section

examination intraoperatively. For severe cases of palmar HH that cause social,

professional and emotional embarassment, bilateral simultaneous UDS by the

supraclavicular approach is the procedure of choice: Morbidity is small, and

almost all patients enjoy improved quality of life after the operation.

 

PMID: 879872 [PubMed - indexed for MEDLINE]

 

 

 

457: Lancet  1977 Jun 18;1(8025):1320

 

Thoracic endoscopic sympathectomy for treatment of upper-limb hyperhidrosis.

 

Kux M.

 

Publication Types:

Letter

 

PMID: 68424 [PubMed - indexed for MEDLINE]

 

 

 

458: Anaesth Intensive Care  1977 Feb;5(1):76-7

 

Case report: hazards associated with cervico-thoracic sympathectomy.

 

Zee RF.

 

PMID: 320907 [PubMed - indexed for MEDLINE]

 

 

 

459: Australas J Dermatol  1976 Dec;17(3):90-1

 

Surgical aspects of hyperhidrosis.

 

Jepson RP, Harris JD.

 

PMID: 1023878 [PubMed - indexed for MEDLINE]

 

 

 

460: Australas J Dermatol  1976 Dec;17(3):82-6

 

Sweating--physiology and pathophysiology.

 

Frewin DB, Downey JA.

 

PMID: 1023876 [PubMed - indexed for MEDLINE]

 

 

 

461: Practitioner  1976 Sep;217(1299):416-9

 

The surgical treatment of hyperhidrosis.

 

Ellis H.

 

The diagnosis of primary hyperhidrosis is one of exclusion, but it is not a

difficult one to make. It is a common, embarrassing and even disabling

condition. If it does not respond to simple conservative therapy, the

practitioner should not hesitate to advise sympathectomy for hyperhidrosis of

the upper or lower limbs, or some simple local operation on the affected skin

area for localized excessive axillary sweating.

 

PMID: 981132 [PubMed - indexed for MEDLINE]

 

 

 

462: Acta Physiol Scand  1976 Jul;97(3):385-91

 

Local nervous mechanism in regulation of blood flow in human subcutaneous

tissue.

 

Henriksen O.

 

The effect of local venous stasis upon blood flow in human subcutaneous adipose

tissue on the distal part of the forearm was investigated in three healthy

subjects and two chronically sympathectomized patients suffering from manual

hyperhidrosis. The area under study was separated into two parts by means of a

lead shield exerting a pressure of about 360 mmHg on the skin. The effect of

venous stasis of about 40 mmHg on one side of the shield upon blood flow

measured simultaneously on both sides of the shield by the local 133Xenon

washout technique was investigated. During venous stasis on one side of the

shield, blood flow decreased about 40% on both sides. The vasoconstrictor

impulse could be transmitted over a distance of about 1-2 cm. The phenomenon was

unaffected by nerve blockade induced 3 cm proximally, medially, and laterally to

the area by infiltration the skin with lidocaine. Thus a vasoconstrictor impulse

could be transmitted from the side of stasis to the non stasis side of the lead

shield. The transmission was not affected by phentolamine but was blocked by

lidocaine and chronic sympathetic denervation. The vasoconstrictor impulse

elicited during venous stasis is therefore most likely transmitted by means of a

local nervous mechanism involving sympathetic adrenergic vasoconstrictor fibres.

 

PMID: 961451 [PubMed - indexed for MEDLINE]

 

 

 

463: Acta Physiol Scand  1976 Jul;97(3):377-84

 

Effect of chronic sympathetic denervation upon local regulation of blood flow in

human subcutaneous tissue.

 

Henriksen O.

 

The effect of chronic sympathetic denervation upon the vasoconstrictor response

to an increase of vascular transmural pressure in human subcutaneous adipose

tissue was investigated in 6 patients suffering from manual hyperhidrosis.

Changes in transmural pressure were obtained either by postural changes of a

forearm or by venous stasis of 30 mmHg. Blood flow was measured in the distal

part of the forearm or crus by means of the local 133Xenon washout technique. 2

patients were studied before and after sympathectomy. When the area under study

was lowered about 40 cm below the jugular notch, blood flow decreased about 50%

preoperatively, about 30% 24 h after the operation, but remained constant 4 days

after or later. Similar results were obtained during venous stasis. Hence about

4 days after sympathectomy, the vasoconstrictor response to an increase in

vascular transmural pressure was abolished. In 3 chronically sympathectomized

patients blood flow remained constant in the denervated limb, but decreased

significantly in the control limb. In another patient studied 580 days after

surgery blood flow remained constant during lowering of the denervated forearm

as well as during venous stasis. These findings might indicate that the

vasoconstrictor response to an increase in vascular transmural pressure in human

subcutaneous adipose tissue is due to a local nervous mechanism involving

symphathetic adrenergic nerves, but a myogenic mechanism cannot be definitively

excluded.

 

PMID: 961450 [PubMed - indexed for MEDLINE]

 

 

 

464: Harefuah  1976 Apr 1;90(7):309-11

 

[Phenomena associated with sympathectomy following hyperhidrosis]

 

[Article in Hebrew]

 

Shoenfeld Y, Kurchin A, Shapiro Y, Machtiger A, Adar R.

 

PMID: 1278790 [PubMed - indexed for MEDLINE]

 

 

 

465: Practitioner  1976 Feb;216(1292):149-53

 

Hyperhidrosis and hypohidrosis.

 

Tan SG, Cutliffe WJ.

 

Sweating has an important physiological function concerned with both temperature

and fluid balance. Hypohidrosis is uncommon and rarely recognized by the

patient. It usually represents damage to the central nervous system or

peripheral nerves. Hyperhidrosis may be a feature of general medical diseases

such as thyrotoxicosis and fevers. It may also be due to damage of the central

of peripheral sympathetic nerves. Localized hyperhidrosis tends to occur on the

palms, the soles, the axillae and, to a lesser extent, the face. Treatment of

local hyperhidrosis with topical aluminium salts, or with topical or oral

anticholinergics, may help some patients but surgery may be indicated in those

with severe hyperhidrosis.

 

Publication Types:

Review

 

PMID: 177967 [PubMed - indexed for MEDLINE]

 

 

 

466: Arch Surg  1976 Jan;111(1):13

 

Editorial: The treatment of axillary hyperhidrosis.

 

Goldwyn RM.

 

PMID: 1106354 [PubMed - indexed for MEDLINE]

 

 

 

467: Dermatologica  1976;152(5):257-62

 

Sweat studies in hyperhidrosis palmaris and plantaris. A survey of 60 patients

before and after cervical sympathectomy.

 

Shoenfeld Y, Shapiro Y, Machtiger A, Magazanik A.

 

60 patients suffering from excessive sweating in the hands underwent cervical

sympathectomy. At follow-up 1-7 years after operation the hands were dry in 55.

No differences in electrolyte concentrations were found in the sweat from palms,

arms, or body prior to and after the surgical intervention. Similarly no

differences were found in electrolyte concentrations between healthy subjects

and hyperhidrotics. Palmar sweat was hypertonic in comparison to arm or body

sweat. The Na and K sweat concentrations were: palmar 50 +/- 20 and 16 +/- 7

mEq/1; arm 30 +/- 11 and 8 +/- 2 mEq/1; and body 21 +/- 20 and 4 +/- 3 mEq/1,

respectively. Na/K ratio was: palmar 3.2; arms 3.6 and body 5.8. Total sweat

loss prior to the operation was 5.7 +/- 4.2 g/kg BW/h; afterwards it was 5.9 +/-

4 g/kg BW/h. These equal sweat rates were associated with compensatory sweating

in areas of the body not affected prior to the operation.

 

PMID: 955224 [PubMed - indexed for MEDLINE]

 

 

 

468: J Chir (Paris)  1976;112(5):307-14

 

[Surgical indications and results of thoracic sympathectomy]

 

[Article in French]

 

Gruss JD, Bartels D, Stojanovic R.

 

Between the 1st of July 1971 and the 31st of December 1974, among 1,459

operations on vascular surgery, we carried out 77 thoracic sympathectomies in 46

patients. In most patients there was an oblitering angiopathie of digital type,

stage II to IV, confirmed by angiography. Two patients had mixed type

obstructions, two others had hyperhidrosis, one patient suffered from

cleroderma, another had a thoracic outlet syndrome with digital arterial

obstruction. In all cases, the transaxillary approach was that which caused the

least complications and which permitted satisfactory exposure of the sympathetic

nerve. The cosmetic results were good. The second and third thoracic ganglia

were resected and the planes of cleavage marked with silver clips. In advanced

stage III and stage IV, we noted 92 p. 100 improvements i.e. return to stages I

or II. The operative mortality was nil. The most serious complication was a case

of hemothorax which required later pulmonary decortication. We noted in two

cases, a Horner's syndrome.

 

PMID: 1010860 [PubMed - indexed for MEDLINE]

 

 

 

469: J Physiol  1976 Jan;254(1):74P-75P

 

Proceedings: Physiological gustatory sweating.

 

Allen JA, Morton WS, Roddie IC.

 

PMID: 1249770 [PubMed - indexed for MEDLINE]

 

 

 

470: Scand J Plast Reconstr Surg  1976;10(2):107-12

 

Innervation of human axillary sweat glands. Histochemical and electron

microscopic study of hyperhidrotic and normal subjects.

 

Rechardt L, Waris T, Rintala A.

 

Adrenergic nerves were demonstrated by formaldehyde-induced fluorescence and

cholinergic nerves using thiocholine techniques to demonstrate

acetylcholinesterase activities at the light and electron microscopic levels.

The specimens were taken during surgery from the axillae of hyperhidrotic

patients and normal voluntary controls. No fluorescent nerves were found around

eccrine or apocrine sweat glands in hyperhidrotic or normally sweating axillae.

Both eccrine and apocrine sweat glands exhibited a nerve network showing

acetylcholinesterase activity. There was no marked difference in the innervation

patterns or in the intensity of the acetylcholinesterase reaction of the nerves

in the hyperhidrotic patients or normal subjects. Ultrastructurally the

acetylcholinesterase-positive nerves were seen in the vicinity of both eccrine

and apocrine glands, but these nerves were outside the basement membrane.

 

PMID: 1019585 [PubMed - indexed for MEDLINE]

 

 

 

471: Acta Physiol Scand  1975 Sep;95(1):83-8

 

Effect of spinal sympathetic blockade upon local regulation of blood flow in

subcutaneous tissue.

 

Henriksen O, Alsner T.

 

The influence of spinal sympathetic blockade upon local regulation of blood flow

in subcutaneous adipose tissue was investigated in six subjects. The effect of

changes in orthostatic pressure on blood flow in subcutaneous tissue in the crus

and distal forearm was measured before and after sympathetic blockade obtained

by epidural anesthesia in 4 subjects and by a bilateral sympathectomy in 2

patients suffering from manual hyperhidrosis. Blood flow in subcutaneous tissue

measured by 133Xe washout technique decreased by about 40 per cent when the limb

was lowered, and remained constant during 30 cm elevation. This was found both

before and after the blockade, though in one of the patients, the orthostatic

decrease in blood flow was less pronounced 24 h after sympathectomy. Hence

central sympathetic reflexes do not alter local orthostatic changes of blood

flow in subcutaneous tissue. These changes therefore are most likely due to

local mechanisms.

 

PMID: 1180107 [PubMed - indexed for MEDLINE]

 

 

 

472: Postgrad Med  1975 Sep;58(3):191-6

 

Hyperhidrosis and its surgical management.

 

Ellis H.

 

PMID: 1161657 [PubMed - indexed for MEDLINE]

 

 

 

473: Aust N Z J Surg  1975 May;45(2):143-6

 

A comparison of the supraclavicular and axillary approaches to upper thoracic

sympathectomy.

 

Little JM, May J.

 

Twenty-nine upper dorsal sympathectomies have been carried out in 18 patients

and a comparison made of the supraclavicular with the axillary approach to the

upper thoracic sympathetic chain. Thirteen of these operations were carried out

for essential hyperhidrosis, 15 for ischaemia in the hand and one for

post-traumatic pain syndrome. Fourteen sympathectomies were carried out through

the axilla and 15 through the supraclavicular approach. Post-operative pain was

felt to be somewhat more severe when the axillary approach was used, but other

complications were infrequent and hospital stay was slightly shorter in the

axillary group. The axillary approach was felt to offer superior exposure, the

capability for wider sympathetic excision, good cosmetic results, avoidance of

Horner's syndrome and low morbidity. In the absence of lung disease or the need

for a direct exploration of the root of the neck, the axillary approach is to be

preferred for upper dorsal sympathectomy.

 

PMID: 1059396 [PubMed - indexed for MEDLINE]

 

 

 

474: Med J Aust  1975 Mar 1;1(9):267-70

 

Upper dorsal sympathectomy.

 

Atkinson L.

 

PMID: 1128419 [PubMed - indexed for MEDLINE]

 

 

 

475: Acta Neurol Scand  1975 Feb;51(2):167-72

 

Palmar hyperhidrosis. Long-term results following high thoracic sympathectomy.

 

Gjerris F, Olesen HP.

 

Fourteen men and 22 wemon, with an average of 23 years (range 14-36 years) were

operated on for hyperhidrosis of the upper extremity during the period from 1955

to 1970. Twenty-eight had had symptoms for more than 10 years. Resection of the

2nd and 3rd thoracic ganglia and the connecting sympathetic chain was carried

out using a posterior approach; in 33 cases the operation was bilateral, and in

three unilateral. Thirty-five patients were followed up after an average of 7.8

years (range 2-17 years). In one patient unilateral reoperation was carried out

four months after the first operation. Since the first operation 34 patients had

suffered from neither palmar nor axillary sweating. However 20 had permanent

compensatory hyperhidrosis, and 15 suffered from gustatory facial sweating,

which had usually started within six months of operation. Four, in whom two

spinal thoracic nerves had also been resected, reported marked dysaesthesia over

the front of the chest and in the axilla, lasting for several years.

 

PMID: 1114879 [PubMed - indexed for MEDLINE]

 

 

 

476: Ir Med J  1974 Oct 26;67(20):544-5

 

The surgical treatment of hyperhidrosis.

 

Keaveny TV, Fitzpatrick J, Fitzgerald PA.

 

PMID: 4443195 [PubMed - indexed for MEDLINE]

 

 

 

477: Br J Plast Surg  1974 Apr;27(2):196-7

 

A serious complication of an operation for axillary hyperhidrosis.

 

Shaw MH.

 

PMID: 4834034 [PubMed - indexed for MEDLINE]

 

 

 

478: Harefuah  1974 Mar 1;86(5):238-9

 

[The electroencephalogram in hyperhidrosis palmo-plantaris]

 

[Article in Hebrew]

 

Shafrir A, Haim S, Cohen A, Yahel M.

 

PMID: 4830204 [PubMed - indexed for MEDLINE]

 

 

 

479: Otolaryngol Clin North Am  1974 Feb;7(1):217-50

 

Physiologic problems following ablative surgery of the head and neck.

 

Summers GW.

 

PMID: 4812642 [PubMed - indexed for MEDLINE]

 

 

 

480: Ann Chir Gynaecol Fenn  1974;63(4):318-25

 

Upper limb sympathectomy.

 

Koikkalainen K, Luosto R, Keskitalo E, Melartin E.

 

PMID: 4416798 [PubMed - indexed for MEDLINE]

 

 

 

481: Contemp Neurol Ser  1974;(11):179-98

 

Disorders of the autonomic nervous system.  Chapter 10.  Sweating.

 

Johnson RH, Spaulding JM.

 

Publication Types:

Review

 

PMID: 4375553 [PubMed - indexed for MEDLINE]

 

 

 

482: J Am Med Womens Assoc  1973 Nov;28(11):581-5

 

The surgical management of axillary hyperhidrosis.

 

Letterman G, Schurter M.

 

Publication Types:

Review

 

PMID: 4358475 [PubMed - indexed for MEDLINE]

 

 

 

483: Harefuah  1973 Oct 15;85(8):357-9

 

[Upper thoracic sympathectomy for palmar hyperhidrosis]

 

[Article in Hebrew]

 

Walden R, Adar R, Zur N, Mozes M.

 

PMID: 4775983 [PubMed - indexed for MEDLINE]

 

 

 

484: Dtsch Med Wochenschr  1973 Mar 9;98(10):518

 

[Hyperhidrosis]

 

[Article in German]

 

Delius L.

 

PMID: 4691577 [PubMed - indexed for MEDLINE]

 

 

 

485: Surg Gynecol Obstet  1972 Oct;135(4):586-8

 

Hyperhidrosis of the upper extremity and its treatment.

 

Hartfall WG, Jochimsen PR.

 

PMID: 5077726 [PubMed - indexed for MEDLINE]

 

 

 

486: Plast Reconstr Surg  1972 Jun;49(6):639-42

 

Further concepts in gustatory sweating.

 

McGibbon BM, Paletta FX.

 

PMID: 4337454 [PubMed - indexed for MEDLINE]

 

 

 

487: Med J Aust  1971 Aug 21;2(8):446-7

 

Essential hyperhidrosis.

 

Collison DR.

 

PMID: 5095712 [PubMed - indexed for MEDLINE]

 

 

 

488: Med J Aust  1971 Aug 14;2(7):390

 

Essential hyperhidrosis.

 

Grant G.

 

PMID: 5092900 [PubMed - indexed for MEDLINE]

 

 

 

489: Med J Aust  1971 Jul 17;2(3):135-8

 

Essential hyperhidrosis.

 

Harris JD, Jepson RP.

 

PMID: 5096178 [PubMed - indexed for MEDLINE]

 

 

 

490: Br Med J  1971 Feb 6;1(744):332-4

 

Role of sympathectomy for hyperhidrosis.

 

Greenhalgh RM, Rosengarten DS, Martin P.

 

PMID: 5100267 [PubMed - indexed for MEDLINE]

 

 

 

491: Cleve Clin Q  1969 Apr;36(2):79-83

 

Essential hyperhidrosis--pathogenesis and treatment. Report of seven cases

treated by upper horacic sympathectomy.

 

Dohn DF, Zraik O.

 

PMID: 5789155 [PubMed - indexed for MEDLINE]

 

 

 

492: Aust N Z J Surg  1969 Feb;38(3):221-3

 

Cervico-dorsal sympathectomy in the management of essential hyperhidrosis in the

upper limb.

 

Renwick S, Loewenthal J.

 

PMID: 5251158 [PubMed - indexed for MEDLINE]

 

 

 

493: Aust N Z J Surg  1968 Nov;38(2):98-103

 

Gustatory sweating.

 

Adie R.

 

PMID: 4302030 [PubMed - indexed for MEDLINE]

 

 

 

494: Fortschr Neurol Psychiatr Grenzgeb  1968 May;36(5):261-74

 

[The so-called gustatory sweating]

 

[Article in German]

 

Schiffter R, Schliack H.

 

PMID: 4307534 [PubMed - indexed for MEDLINE]

 

 

 

495: Nurs Mirror Midwives J  1968 Mar 29;126(10):40

 

Hyperhidrosis.

 

Corrigan MJ, Kildea MM.

 

PMID: 5184802 [PubMed - indexed for MEDLINE]

 

 

 

496: Eye Ear Nose Throat Mon  1967 Mar;46(3):316-20 passim

 

Gustatory sweating.

 

Holloway RM.

 

PMID: 4292468 [PubMed - indexed for MEDLINE]

 

 

 

497: Bull Soc Fr Dermatol Syphiligr  1967;74(6):730-3

 

[The surgical treatment of axillary hyperhidrosis]

 

[Article in French]

 

Preaux J.

 

PMID: 5590517 [PubMed - indexed for MEDLINE]

 

 

 

498: Arch Otolaryngol  1966 Mar;83(3):260-5

 

Gustatory sweating. Report of a case treated by tympanic neurectomy.

 

Hunt W, Joseph D, Newell R, Hanna HH.

 

PMID: 5904049 [PubMed - indexed for MEDLINE]

 

 

 

499: Berufsdermatosen  1965 Jun;13(3):159-70

 

[On experiments in the prevention of professional hyperhidrosis of the hands]

 

[Article in German]

 

Borelli S, Graf W.

 

PMID: 5851684 [PubMed - indexed for MEDLINE]

 

 

 

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